Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Erecevit, Pinar(3)
- Kirbag, Sevda(3)
- Emre, Mustafa Yunus(2)
- Adiguzel, Ragip(1)
- Aksakal, B.(1)
- Aksoy, A.(1)
- Aksoy, M.E.(1)
- Alataş, Mevlüt(1)
- Albayrak, S.(1)
- Arslan, Ali(1)
- Aslan, N.(1)
- Aydoğdu, Burcu(1)
- Aytar, Mehmet(1)
- Bagci, Eyup(1)
- Buldurun, Kenan(1)
- Canpolat, Erdal(1)
- Cinar, A. E. Korkmaz(1)
- Civelek, Semsettin(1)
- Coteli, Ebru(1)
- Digrak, Metin(1)
- Dikici, A.(1)
- Diraz, Emel(1)
- Emre, Irfan(1)
- Emre, İ.(1)
- Erecevi̇, P.(1)
- Gulec, Azime Kucukgul(1)
- Gurler, Nedim(1)
- Guvenc, Ayse Nilay(1)
- Göktaş, Bünyamin(1)
- Güngören, Muhammed(1)
- Gürler, Nedim(1)
- Karagulle, Burcu(1)
- Karaman, Sengul(1)
- Kok, Mediha(1)
- Korkoca, Hanifi(1)
- Kursat, Murat(1)
- Kurşat, M.(1)
- Paksoy, M. Y.(1)
- Paksoy, Mehmet Yavuz(1)
- Pekdemir, Mustafa Ersin(1)
Yayınlar
- MakaleAçık Erişim2026Scopus SJRQ2Multifunctional PLA/PHA-Based films incorporating Moluccella spinosa extract for sustainable and antimicrobial food packaging applications
Selcuk Pekdemir, Sibel; Gurler, Nedim; Yilmaz Sancar, Pelin; Karagulle, Burcu; Kok, Mediha; Pekdemir, Mustafa Ersin; Qader, Ibrahim Nazem
In this study, a novel plant-based shape memory biocomposite was developed for sustainable food packaging applications. A poly(lactic acid)/poly(hydroxyalkanoate) (PLA/PHA) blend was reinforced with the ethanolic extract of Moluccella spinosa, a plant recognized for its bioactive constituents. Structural and thermal analyses confirmed the successful incorporation of the extract without compromising the polymer matrix integrity. The results demonstrated improved barrier performance, characterized by lower water vapor permeability, reduced moisture content, and slightly increased opacity with increasing concentrations of M. spinosa extract. In addition, the composite films exhibited enhanced shape memory behavior, which became more pronounced at higher extract concentrations. Antimicrobial assays revealed a limited and selective inhibitory effect, primarily against Gram-positive bacteria (Enterococcus faecalis and Clostridium perfringens), while no notable activity was observed against Escherichia coli and Staphylococcus aureus. These findings indicate a preliminary antimicrobial potential, likely associated with a sustained-release mechanism rather than strong bactericidal activity. Overall, the integration of M. spinosa extract into the PLA/PHA matrix offers a promising route to design multifunctional, biodegradable packaging materials with shape memory capability, where antimicrobial functionality serves as a complementary feature, contributing to the advancement of environmentally friendly and active food packaging technologies.
- MakaleYayıncıda açık erişim2026Scopus SJRQ1Phenolic Profiling of Some Bryophyte Species: In Vitro and In Silico Assessment of Their Antimicrobial Potentials
Çambay, Zafer; Uslu, Harun; Coteli, Ebru; Göktaş, Bünyamin; Özdemir Bayçinar, Kevser; Emre, Mustafa Yunus; Güngören, Muhammed; Alataş, Mevlüt
This study explores the phytochemical composition and antimicrobial potential of Palustriella commutata, Philonotis calcarea, Cinclidotus riparius, Rhynchostegium riparioides, Plagiomnium ellipticum, and Porella platyphylla, with a focus on bryophyte species phenolic constituents and biological activities. HPLC analysis identified seven phenolic acids (4-hydroxybenzoic acid, 2,5-dihydroxybenzoic acid, 3,4-dihydroxybenzoic acid, caffeic acid, vanillic acid, syringic acid, and p-coumaric acid) across all species in varying concentrations. In in vitro antimicrobial tests, the bryophyte extracts used showed significant activity against Pseudomonas aeruginosa (ATCC 9027), while exhibiting relatively lower inhibition against Staphylococcus aureus (ATCC 25923). The study showed that all species extracts exhibited comparable activity to erythromycin against P. aeruginosa, while Cinclidotus riparius and Plagiomnium ellipticum extracts showed no activity against S. aureus, and the remaining species exhibited lower activity compared to erythromycin. Molecular docking studies demonstrated strong binding affinities of these phenolics to the active site of the target macromolecule (PDB ID: 3FRQ), suggesting meaningful interactions with residues such as ARG122 and ASN123, similar to erythromycin binding patterns. The findings indicate that bryophyte-derived phenolic compounds possess significant antimicrobial potential and may serve as promising candidates for the development of novel bioactive agents. This study provides a broad framework for the insufficiently researched antimicrobial potential of bryophytes by establishing direct links between species-specific phenolic fingerprints, experimentally observed antibacterial activities, and predicted receptor-level interactions. Further complementary biological studies are needed to confirm and expand upon these results.
- MakaleAçık Erişim2025Scopus SJRQ1Green Synthesis of Multi-Walled Carbon Nanotube-Reinforced Hydroxyapatite Doped with Silver and Silver-Core Selenium-Shell Nanoparticles: Synthesis, Characterization, and Biological Activity
Unal, İlkay
Hydroxyapatite (HAp) is widely used in biomedical applications due to its biocompatibility, osteoconductivity, and bioactivity. However, its low mechanical strength, tendency toward rapid corrosion, and lack of bactericidal properties present significant limitations in applications. This study aimed to improve the properties of HAp by reinforcing it with multi-walled carbon nanotubes (MWCNTs) and doping it with silver nanoparticles (AgNPs) and silver-core selenium-shell nanoparticles (Ag@SeNPs). Ocimum basilicum extract was used as both a reducing and stabilizing agent in the synthesis of nanoparticles using an environmentally friendly and non-toxic method as an alternative to traditional methods. The synthesized HAp, HAp/MWCNT, Ag-HAp/MWCNT, and Ag@Se-HAp/MWCNT nanocomposites were characterized by TEM, SEM, XRD, Raman spectroscopy, and BET analysis. BET analysis showed a reduction in surface area from 109.4 m2/g for pure HAp to 71.4 m2/g, 47.5 m2/g, and 35.3 m2/g for HAp/MWCNTs, Ag- HAp/MWCNTs, and Ag@Se-HAp/MWCNTs, respectively. Antimicrobial activities against P. aeruginosa, E. coli, S. aureus, E. faecalis, and C. albicans were evaluated. HAp and HAp/MWCNT did not show any antimicrobial activity, while Ag-HAp/MWCNTs showed inhibition zones of 14 mm for Escherichia coli and 18 mm for Pseudomonas aeruginosa at 5 mg/mL. Ag@Se-MWCNTs/HAp exhibited superior efficacy with inhibition zones of 18 mm, 12 mm, and 20 mm for S. aureus, E. faecalis, and Candida albicans, respectively. The incorporation of Ag@SeNPs enhanced HAp’s antibacterial and antifungal properties through a synergistic mechanism.
AtıfScopus12WoS10OpenAlex12
İncele - MakaleYalnız künye2024Scopus SJRQ2Plant extract-based biosynthesis of silver nanoparticle and silver–zinc nanocomposites-doped hydroxyapatite and its antimicrobial activity
Unal, Ilkay; Aydoğdu, Burcu; Aytar, Mehmet
Hydroxyapatite (HAp) is an essential material in the biomedical field because of its chemical composition, similar to the apatites found in bones. The lack of bactericidal properties of HAp-based materials cannot prevent the adhesion and growth of bacteria. However, it can develop composite biomaterials using nanoparticles (NPs) such as silver (Ag) and zinc (Zn), which exhibit biocidal behaviours to control resistant microorganisms. This study aimed to prepareHAp–AgNPs and HAp–Ag@ZnNPs nanocomposite and evaluate their antimicrobial properties against Gram-positive and Gram-negative bacteria. HAp powders were produced from sheep bone. An aqueous extract of Marrubium astracanicum was used as a reducing and stabilising agent for the synthesis of NPs. The composites were characterized by XRD, SEM–EDX, SEM and FTIR. In vitro biocompatibility assessment was determined by agar well diffusion tests. The HAp–Ag@ZnNPs nanocomposites showed stronger antimicrobial activity than HAp–AgNPs against bacteria and fungi, while pure HAp did not show any effect.
AtıfScopus6WoS5OpenAlex4İncele - MakaleYalnız künye2024Scopus SJRQ3Biogenic Silver and Zinc Enhanced MWCNTs: Nano-Decoration, Characterization, and Antimicrobial Effect
Ünal, İlkay
In this study, acid-treated multi-walled carbon nanotubes (MWCNTs) were decorated with silver (Ag), zinc (Zn), and Ag@Zn nanoparticles (NPs) synthesized using plant extract for reducing and stabilizing NPs. The nanocomposites were characterized by Scanning electron microscopy (SEM)-energy-dispersive X-ray spectroscopy (EDX), Transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), Raman spectroscopy, and Thermogravimetric analysis (TGA). The stability of functionalized MWCNTs (f-MWCNTs) and NP-decorated MWCNTs was visually evaluated for seven days in ethanol. The antimicrobial efficacy against Gram-positive (Staphylococcus aureus), Gram-negative (Pseudomonas aeruginosa, Escherichia coli) bacteria, and fungi (Candida albicans) was determined using the agar well diffusion assay. Results indicated that Ag-MWCNTs and Ag@Zn-MWCNTs nanocomposites exhibited superior antimicrobial activity against P. aeruginosa and C. albicans compared to other tested microorganisms. Conversely, f-MWCNTs and Zn-MWCNTs showed no antimicrobial effects.
AtıfScopus1WoS1OpenAlex1İncele - MakaleAçık Erişim2023Scopus SJRQ4Cu(II) Complexes of New Sulfa Drug Schiff Base Ligands: Synthesis, Structural Characterization, Antimicrobial Activities, and Time-Killing Kinetics
Şahal, Hakan; İdil, Önder; Canpolat, Erdal; Özkan, Mustafa
Abstract: Synthesis of three different new sulfonamide compounds (L1–L3) and their Cu(II) complexes were carried out. Their structures were characterized by spectroscopic methods such as Fourier transform infrared, Proton nuclear magnetic resonance and elemental analysis. Cu(II) complexes were screened for Gram-positive, Gram-negative bacteria and against yeast using the microdilution method. In particular, CuL2 was found to have significant antimicrobial effects on Gram (–), Gram (+) and eukaryotic yeast. The results showed that CuL2 exhibited better antimicrobial activity than other complexes. Depending on the antimicrobial activity results, time killing experiments of CuL2, the most effective complex, were performed.
AtıfScopus3WoS2OpenAlex2İncele - MakaleYalnız künye2022Scopus SJRQ3Boron-incorporated biocomposite coatings on 316L and NiTi alloys: Enhanced structural, antibacterial activity, and cell viability performances
Aslan, N.; Aksakal, B.; Aksoy, M.E.
Boron doped (5 %, 10%, and 15 wt.%) Hydroxyapatite (B-HA) biocomposites were syntesized and coated on 316L SS and NiTi (Ni-45Ti) metallic substrates by using the electrophoretic deposition process (EPD). The morphological and structural characterization of the coatings was executed using scanning electron microscopy (SEM) and X-ray diffraction devices (XRD). Antibacterial tests were conducted using Escherichia coli (E. coli, JM103) and Staphylococcus aureus (S. aureus, ATCC29293) microorganisms. The mitochondrial activity assay (MTT)-[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] was used to examine cell viability and cytotoxicity in Saos-2 osteoblast cells. HA and boron peaks, as well as B-TCP and metallic components, were detected in XRD examinations. Porous morphologies were generated on the surface with boron doped B-HA coatings, as revealed by SEM views. Antibacterial activity studies revealed that both metallic coating groups, notably with boron doping, demonstrated antibacterial activity against gram-negative E. coli and gram-positive S. aureus. The antibacterial activity of the 316L group was shown to be better than that of the NiTi group in comparisonal testing. The syntesized boron-doped biocomposite coatings did not have any detrimental effects on living cells, according to cell viability studies. The cell viability rate was found to be greater in NiTi coatings than in 316 SS coatings, and the impact was amplified by the addition of boron.
AtıfScopus6WoS4OpenAlex7İncele - MakaleYalnız künye2022Scopus SJRQ2Synthesis, characterization, pH-sensitive swelling and antimicrobial activities of chitosan–graft-poly(hydroxyethyl methacrylate) hydrogel composites for biomedical applications
Torğut, Gülben; Yazdıç, Ferit Can; Gürler, Nedim
In this paper, 2-hydroxyethyl methacrylate (HEMA) was graft copolymerized onto chitosan (CHI) at different ratios using a radical initiator. The grafted hydrogel composites were then characterized by attenuated total reflection Fourier transform ınfrared spectroscopy (ATR-FTIR) and thermo-gravimetric analysis (TGA). Swelling behavior of the hydrogels was investigated at different pH and different times. The antimicrobial activity of the chitosan-graft-HEMA (CHI-HEMA) against gram-negative bacteria and gram-positive bacteria was studied by the standard agar well diffusion assay method. The CHI-HEMA 1:1 and CHI-HEMA 1:2 showed an obvious antimicrobial effect against six test strains. The CHI-HEMA 1:1 and CHI-HEMA 1:2 exhibited a highly significant increase (p < 0.01) in diameter of the inhibition zones compared with the standard antibiotics. Furthermore, CHI-HEMA 1:1 presented the highest antimicrobial activity against all test strains with a significant difference (p < 0.01) compared with CHI-HEMA 1:2. Meanwhile, the decreasing order of the average sensitivity to CHI-HEMA 1:1 and CHI-HEMA 1:2 was observed to be S. marcescens > E. coli > S. aureus subsp. aureus > S. enteritidis > E. faecalis > E. aerogenes. These results indicate potential application of CHI-HEMA 1:1 and CHI-HEMA 1:2 graft hydrogels as a novel and efficient antimicrobial agent in biomedical fields.
AtıfScopus40WoS36İncele - MakaleYalnız künye2021Scopus SJRQ4Balneotherapy Features of Natural Thermal Source from Pertek (Turkey-Tunceli) Due to Its Some Chemical, Radioactivity and Biological Parameters
Sönmez, Pinar Erecevit
It can also be defined as a discipline that reviews the factors of balneology or hydrotherapy, which are alternative treatment methods for public health, from chemical, biological and medical aspects. In this study, it was aimed to investigate whether the underground waters in the Pertek district of Tunceli province are suitable for balneology. Chemical, radioactivity analysis, microbiological quality, antimicrobial activities were determined in relation to natural groundwater and its ability to be a natural healing source was investigated. When the chemical content is examined, it was determined to be bromide amount is 0.24 mg / L, Iodine (I); 1.9 mg / L, sulfur (S); 0.02 mg / L, boron (B): 2676 µg / L, silicium (Si); 1.9 mg / L. With respect to the results, thermal water has the feature to be used in balneolotherapy. According to the results of the radioactivity analysis, alpha (α) is 0.15 Bq / L; Beta (β) is <0.30 Bq / L and radon (Rn) is <13.4 Bq / L tritium (T) content is <10 Bq / L (<83.33 TB) and it is included in both mineral and young water group. This ground water and they comply with the standards in terms of microbiology (Total bacteria, coliform, Escherichia coli). Its antibacterial, antifungal and antidermatophyte properties prove to be a healing source. We confirmed the effectiveness of this healing water to both protect and promote human health as a drinking cure and reach the newest and most effective treatment modalities by using related water in Health and Thermal Tourism.
- MakaleAçık Erişim2021The antioxidant and antimicrobial capacities of phenolic profiles of some Salvia L. Seeds grown in Turkey
Emre, Irfan; Kursat, Murat; Kirbag, Sevda; Erecevit, Pinar; Emre, Mustafa Yunus; Yilmaz, Okkes; Civelek, Semsettin
The aim of current study is to show phenolics, antioxidant capacities and antimicrobial activities of seeds of five Salvia L. (S. frigida Boiss., S. candidissima subsp. candidissima Vahl., S. virgata Jacq., S. verticillata L. var. verticillata and S. russellii Benth.) taxa grown in Turkey. The flavonoid and phenolic acid contents were measured by using HPLC whilst the antioxidant capacities were determined by using different methods. In addition, agar well diffusion method was used to determine the antimicrobial activities of Salvia species in this study. It was found that S. frigida, S. verticillata var. verticillata and S. russellii have the highest catechin contents and S. frigida and S. verticillata var. verticillata have high rosmarinic acid while S. frigida, S. candidissima subsp. candidissima and S. verticillata var. verticillata have high vanilic acid. Also, it was determined that S. frigida and S. verticillata var. verticillata have high DPPH radical scavenging activities in 150 and 250 µL while S. frigida and S. verticillata var. verticillata have highest ABTS radical scavenging activity in all concentrations apart from 25 µL for S. frigida. Furthermore, S. frigida and S. verticillata var. verticillata have high total phenolic contents. On the other hand, Salvia species have similar lipid peroxidation inhibitions. However, the metal chelating activities of Salvia species are different. And also, it was demonstrated that Salvia taxa have antimicrobial activity.
AtıfScopus7OpenAlex7TR Dizin2
İncele - MakaleAçık Erişim2021Scopus SJRQ2Chemical compositions, radical scavenging capacities and antimicrobial activities in seeds of satureja hortensis l. And mentha spicata l. subsp. spicata from turkey; [Composições químicas, capacidades radicais eliminadoras e atividades antimicrobianas em sementes de satureja hortensis l. E mentha spicata l. subsp. spicata da turquia]
Emre, İ.; Kurşat, M.; Yilmaz, Ö.; Erecevi̇, P.
The present study determined some biological compounds, radical scavenging activity and antimicrobial capacity in seeds of Satureja hortensis L. and Mentha spicata L. subsp. spicata. Alpha-linolenic acid (C18:3 n3) has been found to be the major polyunsaturated fatty acid of Satureja hortensis L. (66.24 ± 1.24%) and Mentha spicata L. subsp. spicata (48.17 ± 1.01%). Linoleic acid (C18:2 n6) is identified as the second major polyunsaturated fatty acid in the present study and oleic acid (C18:1 n9) is determined as the major monounsaturated fatty acid. Current study showed that Satureja hortensis L. and Mentha spicata L. subsp. spicata have low levels of saturated fatty acids. It has been demonstrated that ergosterol (263.1 ± 2.14 µg/g), stigmasterol (39.07 ± 0.91 µg/g) and beta-sitosterol (14.64 ± 0.49 µg/g) have been found in Mentha spicata L. subsp. spicata, while ergosterol (69.41 ± 1.75 µg/g) and beta-sitosterol (19.81 ± 1.14 µg/g) have been determined in Satureja hortensis L. Also, this study determined that Satureja hortensis L. and Mentha spicata L. subsp. spicata have low lipide-soluble vitamin content. Furthermore, it has been found that Satureja hortensis L. contains naringenin (612.57 ± 2.57 µg/g), morin (86.97 ± 1.12 µg/g), quercetin (22.87 ± 0.75 µg/g), and kaempferol (20.11 ± 0.94 µg/g) while naringenin (135.91 ± 1.91 µg/g), naringin (61.23 ± 2.15 µg/g) and quercetin (47.51 ± 1.17 µg/g) have been detected as major flavonoids in the seeds of Mentha spicata L. subsp. spicata. The results of the present study suggest that methanol extracts of Satureja hortensis L. and Mentha spicata L. subsp. spicata have significant free radical scavenging activity. The present results revealed that Satureja hortensis L. and Mentha spicata L. subsp. spicata showed major activity against gram-positive and gram-negative microorganisms, fungi and yeast.
AtıfScopus14OpenAlex18İncele - MakaleYayıncıda açık erişim2018Scopus SJRQ3Spectral, thermal and antimicrobial properties of novel mixed ligand-metal complexes derived from saccharinate complexes and azo dye ligand
Adiguzel, Ragip; Turan, Nevin; Buldurun, Kenan; Korkoca, Hanifi
Background and Objective: Saccharin and saccharinate (sac) complexes and its anion have critical importance with biological, biochemical and pharmacological properties. The main objective of this study was to synthesize the novel mixed ligand complexes from the complexes [M(Sac)2(H2O)4]·2H2O [M: Mn(II), Co(II), Ni(II), Cu(II) and Cd(II)] with a second neutral ligand [L:(mmppa): 5-Methyl-4-(4-methylphenylazo)-2H-pyrazole-3-ylamine]. Methodology: The structures of the complexes were characterized by elemental analysis, magnetic susceptibility, FT-IR, mass and electronic spectral studies and thermal analysis. Antimicrobial (antibacterial and anticandidal) activities of the complexes were tested against Enterococcus faecalis ATCC 51299, Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 35218, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 700603 and Candida albicans ATCC 64548. Results: According to the experimental results, it was determined that in Mn(II), Co(II) and Cd(II) complexes, two coordinated H2O molecules are replaced with two neutral ligands, on the other hand, in Ni(II) and Cu(II) complexes, all coordinated H2O molecules are replaced with four neutral ligands. It was established that the second neutral ligand was coordinated to the metal ions via nitrogen atom of-NH2 group in pyrazole ring. In antimicrobial activity, study was determined to occur significant inhibition zones (20-24 mm) against Candida albicans ATCC 64548 strain. Conclusion: As a result, mononuclear and monomeric structure in octahedral geometry including both saccharin and azo dye ligands were synthesized and their characterizations were accomplished. The result of this study shows that novel mixed ligand-saccharinate complexes can be utilized for the development of anticandidal agents.
AtıfScopus11WoS10OpenAlex11İncele - MakaleYalnız künye2016Scopus SJRQ1Essential oil composition and antimicrobial activity of two endemic Kundmannia SCOP. species from Turkey
Paksoy, Mehmet Yavuz; Diraz, Emel; Digrak, Metin; Tutar, Esen; Karaman, Sengul
Kundmannia anatolica HUB.-MOR. and Kundmannia syriaca BOISS. are two endemic species of Apiaceae diversified in Turkey. In the present study, the essential oil composition and antimicrobial activity of these endemic species collected from Southeast Anatolia region of Turkey were investigated. Essential oils of aerial parts were obtained by hydro distillation method and analyzed by GC-MS/FID. Acetone, chloroform and methanol extracts of aerial parts of the plants were tested against seven bacteria and three yeasts by disc diffusion method for antimicrobial assays and minimum inhibition concentrations (MIC) were determined. Spathulenol, curdione, apritone, germacrene-d and- (-) globulol were the major components of K. anatolica. In the essential oil of K. syriaca, spathulenol, germacrene-d, bioallethrin, 12-norcyercene-B and beta methadol were determined as the main compounds. The most abundant compound of K anatolica and K. syriaca was spathulenol with 17.40%-19.53% ratio in the GC-MS and 19.7%, 24.99% ratio in GC-FID results, respectively. Aerial parts extracts of K. anatolica and K. syriaca exhibited remarkable antimicrobial activity to all tested microorganisms except for Candida albicans. (C) 2015 Elsevier B.V. All rights reserved.
AtıfWoS12OpenAlex13İncele - MakaleYalnız künye2015Scopus SJRQ3An investigation on antioxidant and antimicrobial activities of four Inula helenium L. taxa
Albayrak, S.; Cinar, A. E. Korkmaz; Paksoy, M. Y.; Aksoy, A.
The antioxidant activities of methanol (ME), ethanol (EE), water (WE) and ethyl acetate (EAE) extracts of four Inula helenium L. taxa (I. helenium ssp. orygalis (Boiss.) Grierson, I. helenium ssp. pseudohelenium Grierson, I. helenium ssp. turcarasemosa Grierson and I. helenium ssp. vanensis Grierson) were investigated. The phosphomolybdenum assay, beta-carotene linoleate bleaching and DPPH radical scavenging activity were used to evaluate the antioxidant capacity. The total phenolic contents determined by Folin-Ciocalteu assay of the extracts ranged from 4.18 to 102.91 mg gallic acid equivalents (GAE)/g dry extract. The extracts showed considerable effect on reducing the oxidation of beta-carotene. The highest radical scavenging activity was obtained for ME of I. helenium ssp. orygalis in DPPH assay. ME, EE and EAE of four Inula helenium taxa showed significant antibacterial activity against 13 bacteria tested. WEs had no inhibitory effect against bacteria tested except for I. helenium ssp. orygalis. EE of I. helenium ssp. orygalis was only effective against C. albicans.
AtıfWoS8İncele - MakaleAçık Erişim2014Scopus SJRQ4Antimicrobial Activity of the Methanol Extracts and Essential Oil with the Composition of Endemic Origanum acutidens (Lamiaceae)
Gulec, Azime Kucukgul; Erecevit, Pinar; Yuce, Ebru; Arslan, Ali; Bagci, Eyup; Kirbag, Sevda
The chemical composition of hydro distilled essential oil from Origanum acutidens (Hand. and Mazz.) Ietswaart was collected from Tunceli (Turkey) were analyzed by GC and GC-MS. Essential oil and methanol extract of Origanum acutidens were tested against Yersinia ruckeri (ATCC 29473), Aeromonas hydrophila (ATCC 607920), Lactococcus garviae (ATCC 43921) Staphylococcus aureus (ATCC 29213) fish pathogenic bacterial strains. The analysis of the essential oil of Origanum acutidens showed the presence of 6 components accounting for 93.8 % of the total amount. Calvacrol (61.8 %), p-cymene (15.5 %) and thymol (12.7 %) that possessed antimicrobial activity were found as the major component. The final concentrations of the methanol extract and the essential oil were determined by using disk diffusion assay. Mean inhibition zones of bacterial strains for Origanum acutidens essential oil varied from 28.0 +/- 1.2 and 36.7 +/- 0.7 mm. The inhibition zones of methanol extract (10 mu L and 20 mu L) of Origanum acutidens against bacterial strains were in the range 8.7 +/- 0.7 - 11.0 +/- 0.6 mm and 12.7 +/- 0.67 - 22.7 +/- 1.3 mm, respectively. Our results suggest that both the methanol extract and the essential oil of Origanum acutidens may be valuable as potential antibacterial agents against the major fish pathogens.
AtıfWoS7OpenAlex12İncele - MakaleAçık Erişim2013Scopus SJRQ3ANTIMICROBIAL ACTIVITIES OF SOME EUPHORBIA SPECIES
Kirbag, Sevda; Erecevit, Pinar; Zengin, Fikriye; Guvenc, Ayse Nilay
In this study, the antimicrobial activities of methanolic extracts and latex of some Euphorbia species used for medical purposes in Turkey were investigated. The extracts of Euphorbia aleppica L., Euphorbia szovitsii Fisch.&Mey. var. harputensis Aznav. ex M. S. Khan, Euphorbia falcata L. sub. falcata var. falcata, Euphorbia denticulata Lam., Euphorbia macroclada Boiss., Euphorbia cheiradenia Boiss.&Hohen, Euphorbia virgata Waldst.&Kit., Euphorbia petiolata Banks&Sol. were prepared with methanol. The antimicrobial activities of these extracts were examined on test microorganisms as follows: Staphylococcus aureus COWAN 1, Bacillus megaterium DSM 32, Proteus vulgaris FMC 1, Klebsiella pneumonia FMC 5, Escherichia coli ATCC 25922, Pseudomonas aeruginosa DSM 50071, Candida albicans FMC 17, Candida glabrata ATCC 66032, Epidermophyton sp. and Trichophyton sp. by the disc diffusion methods and well agar method. The MIC values of extracts were determined according to the broth microdulitions method. Results indicated that extracts of Euphorbia species inhibited the growth of tested microorganisms in the different ratio. Also, the MIC values of extracts were determined as 31,2-1000 mu g.
AtıfWoS29OpenAlex30İncele - MakaleYalnız künye2011Scopus SJRQ2Antibacterial Effects of Some Fermented Commercial and Homemade Dairy Products and 0.9% Lactic Acid against Selected Foodborne Pathogens
Yesillik, S.; Yildirim, N.; Dikici, A.; Yildiz, A.
In this study, the antibacterial effects of homemade yoghurt, commercial yoghurt, commercial kefir and probiotic yoghurt on viability of Salmonella typhimurium (ATCC 14028), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853) and Staphylococcus aureus (ATCC 25923) was investigated by using disc diffusion method. Antibaterial effects of the samples were tested at 24, 48 h and the 7 day intervals. Homemade yoghurt showed the maximum antibacterial effect against the pathogens. It was determined that the most sensitive pathogenic bacteria to dairy products were Salmonella typhimurium whereas the least sensitive pathogen was Pseudomonas aeruginosa. Comparing to the antimicrobial effect of 0.9% lactic acid which was used as positive control, our results concluded that the bacteria found in fermented dairy products have an antibacterial activity and this activity is not caused by only lactic acid.
AtıfWoS23OpenAlex38İncele