Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Gul, Muhammet(82)
- Akkurt, Nevzat(67)
- Güler, Ömer(66)
- Baskonus, Haci Mehmet(62)
- Bulut, Hasan(60)
- Tekin, H.O.(52)
- ALMisned, Ghada(49)
- Yucesan, Melih(43)
- Yildirim, Numan(42)
- Yildirim, Nuran Cikcikoglu(38)
- Paksoy, Mehmet Yavuz(36)
- Serdar, Osman(36)
- Zengin, Gokhan(36)
- Ince, Muharrem(34)
- Celik, Erkan(33)
- Benzer, Fulya(32)
- Kocabaş, Mehmet(30)
- Sulaiman, Tukur Abdulkadir(30)
- Tanyol, Mehtap(29)
- Yildirim, Ozal(28)
- Aslan, Naim(26)
- Kök, Mediha(26)
- Özkul, İskender(26)
- Ates, Mehmet(25)
- Danabas, Durali(25)
- Kutluyer, Filiz(25)
- Can, Erkan(24)
- Kutlu, Banu(23)
- Onat, Onur(23)
- Demir, Veysel(22)
- Erten, Fusun(22)
- Guler, Omer(22)
- Say, Yakup(22)
- Güler, Seval Hale(21)
- Yaman, Mehmet(21)
- Baykal, Duygu Sen(20)
- Sançar, Taylan(20)
- Susam, Selim Orhun(20)
- Cakilcioglu, Ugur(19)
- Orhan, Cemal(19)
Yayınlar
- MakaleYalnız künye2021Scopus SJRQ1Investigation of Some Metal Accumulation Ability of Phragmites australis from Poultry Slaughterhouse Wastewaters
Topal, Murat
In this study, the bioaccumulation of some metals by Phragmites australis plants exposed to poultry slaughterhouse wastewater was investigated. For this aim, Mo, As, Cd, Se, Cu, Zn, Cr, Ba, Ti, Fe, Al, and Mn metals were determined in slaughterhouse wastewaters, P. australis plants, and sediment samples. The uptake of metals by P. australis was investigated. Also, BCF and TF values were calculated and compared with reference plant values. The maximum metal accumulation in P. australis plants exposed to poultry slaughterhouse wastewaters was 5900% for Al and 33.5% for Mn when compared with reference plant values. According to the BCF values, P. australis was bioaccumulative for Mo, Se, and Al. As a result, it was determined that P. australis plant can be used in the remediation of metals found in poultry slaughterhouse wastewaters and would be a good accumulator.
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İncele - MakaleAçık Erişim2021Scopus SJRQ2The comparisons of fatty acid composition in some anaerobic gut fungi neocallimastix, orpinomyces, piromyces, and caecomyces
Kar, Bülent; Özköse, Emin; Ekinci, Mehmet Sait
The objective of this study were to identify the fatty acid composition for decanoic (C10:0), tridecanoic (C13:0), myristic (C14:0), pentadecanoic (C15:0), palmitic (C16:0), stearic (C18:0), oleic (C18:1n9c), linoleic (C18:2n6c), arachidic (C20:0), arachidonic (C20:4n6), heneicosanoic (C21:0), erucic (C22:1n9) and Cis-4,7,10,13,16,19-docosahexaenoic (C22:6n3) acids by Neocallimastix, Orpinomyces, Caecomyces and Piromyces species of rumen fungus during in vitro culture. Fatty acid (FA) profile of anaerobic fungi comprises carbon chains of length ranging from 10 to 22 were analyzed as methyl esters. Analysis of fatty acids was performed using Gas Chromatography-Mass Spectrophotometer (GC-MS). FA measures are presented as proportions of relative amounts (% total fatty acid). The highest amounts of fatty acids for all samples were found as myristic (C14:0) acid. The tridecanoic (C13:0) acid represented the second abundant FA in the fungi in all experimental groups. Stearic acid (C18:0) was the third major fatty acid for isolates investigated in the current study. In addition, another fatty acid was palmitic (C16:0) acid with relative amount representing >20% of total FA in all samples. Pentadecanoic (C15:0) acid could not be found in any other samples except Orpinomyces sp. (GMLF5). It is concluded that biohydrogenation of fatty acid composition by anaerobic gut fungi are very variable.
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İncele - MakaleYalnız künye2021Scopus SJRQ4Body Perceptions of Female Athletes Aged Between 11 and 14
Şakar, Murat; Bayındır, Melek; Kılıç, Tahir
Study Objectives: This study aimed to examine the body perception levels of women aged between 11 and 14, including those not playing sports and playing sports according to their sports branches. Method: the study was carried out with 140 female participants between ages 11 and 14. The study group consists of 80 licensed women athletes playing volleyball (n:28), basketball (n:25), badminton (n:9), and swimming (n:18) and also 60 women who are educated in the same school but do not actively play sports. Participants were included in the study voluntarily. The data were measured for the 2017-2018 academic calendar by using the “The Multidimensional Body-Self Relations Questionnaire (MBSRQ)”. The Turkish validity and reliability of this scale were performed. Results: The appearance orientation scores of individuals who play individual and team sports were found to be significantly lower than those who do not. It was observed that there was a significant difference in the body perception levels of women playing and not playing sports. Moreover, there was a significant difference between the fitness evaluation, fitness orientation, and overall scale scores according to age, branch, and sports status. On the other hand, there was no significant difference between the scores of appearance evaluation, health orientation, body areas satisfaction, appearance orientation, and health evaluation. Conclusion: The formation of a positive body image can be achieved by actively participating in sports and physical activities in adolescence. It should be encouraged as a state policy that adolescents participate in social sportive communities where they can establish healthy relationships. To have adult behaviors and to struggle with life, for individuals with reduced anxiety levels, high self-esteem and self-confidence, and satisfaction with their body image, organized planning and precautions should be performed to adapt them to life.
AtıfWoS1OpenAlex1İncele - MakaleYalnız künye2021Scopus SJRQ2New national and regional bryophyte records, 66
Ellis, L.T.; Alataş, M.; Aleffi, M.; Álvaro Alba, W.R.; Becerra Infante, D.A.; Cárdenas Espinosa, K.A.; Aziz, Md N.; Bakalin, V.A.; Bergamo Decarli, G.; Boiko, M.
AtıfScopus12OpenAlex16İncele - MakaleAçık Erişim2021First Clinical Placement: Nursing Students’ Views
Korkmaz, Fatos; Tarakcioglu Celik, Gul Hatice; Kucukkelepce, Gulhan Erkus; Arslan, Sevda; Gul, Senay
Objective: Analyzing students’ experiences about clinical practice will help instructors prepare learning settings where students can have more positive experiences. The purpose of this article is to identify nursing students’ views regarding their clinical placement. Method: This descriptive study was conducted with fresher’s in a nursing department of university during spring term of the 2014-2015 academic year in Ankara/Turkey. The data was collected with the question forms prepared by the researchers after the final exam of the “Fundamentals of Nursing Course”. 253 students were provided questionnaires to answer, which were collected after completion. Results: Students mean age was 20.2; 85.4% of them were female and 40.3% of them choose this department for employment opportunities. Students evaluated professional competence and presence of nurses, as “Good” and “Very Good” (with 80% to 90%) and, communication between nurse and patient as “Moderate” and “Bad” (with 60%). Prejudices regarding clinical practice (with 38.7%), fear of making mistake (with 55.3%), prejudices toward clinical setting (with 58.5%), and grade anxiety (with 29.2%) were stated as factors that affect clinical learning negatively. Conclusion: Students’ learning was affected by healthcare professions especially nurses, they worked with, instructors as well as some factors stem from themselves (fear of making a mistake, grade anxiety).
AtıfScopus1WoS1İncele - MakaleAçık Erişim2021Scopus SJRQ2Pollen morphology of eight endemic Inula L. (Asteraceae) species in Turkey
Karlıoğlu Kılıç, Nurgül; Yılmaz Dağdeviren, Rüya; Paksoy, Mehmet Yavuz; Tuncalı Yaman, Tutku
The pollen morphology of eight endemic species of the genus Inula L. (Asteraceae)–I. helenium subsp. orgyalis (Boiss.) Grierson, I. helenium subsp. vanensis Grierson, I. macrocephala Boiss. & Kotschy ex Boiss., I. discoidea Boiss., I. sarana Boiss., I. fragilis Boiss. & Hausskn., I. anatolica Boiss. and I. sechmenii Hartvig & Strid–distributed in Turkey was studied with light microscopy and scanning electron microscopy. We found that the pollen of these Inula taxa are prolate-spheroidal in shape (except in Inula discoidea), with the polar axis ranging from 19.18 to 33.14 µm and the equatorial diameter ranging from 18.54 to 32.92 µm. The pollen grains are tricolporate and their ornamentation is echinate. The exine thickness ranges from 0.87 to 2.07 µm. As this study demonstrates, results of Principal Component Analysis are revealed that some of the pollen characters, such as spine length and width, are significant morphological characters for taxonomic discrimination of the eight endemic Inula taxa. According to cluster analysis, two main groups of examined taxa are constituted.
AtıfScopus9WoS9OpenAlex10İncele - MakaleAçık Erişim2021Scopus SJRQ4Regulation of cell signaling pathways by Wogonin in different cancers: Mechanistic review
Butt, Ghazala; Ozbey, Ulku; Malik, Durrshahwar; Attar, Rukset; Youssef, Lara; Farooqi, Ammad Ahmad
Natural products have historically been invaluable as a premium source of therapeutic agents. Recent advancements in genomics and structural biology have portrayed a high-resolution landscape of the diversity of proteins targeted by pharmacologically active products from natural sources. Natural product research has generated valuable wealth of information and cutting-edge research-works have leveraged our conceptual knowledge altogether to a new level. Wogonin (5,7-dihydroxy-8-methoxyflavone) is an O-methylated flavone and has attracted noteworthy appreciation because of its ability to pharmacologically target plethora of cell signaling pathways in different cancers. In this mini-review, we have gathered scattered pieces of available scientific evidence to summarize how wogonin pharmaceutically targeted Wnt/β-catenin, JAK/STAT, VEGF/VEGFR and TRAIL-driven apoptotic pathways in wide variety of cancers. We have also critically analyzed how wogonin prevented carcinogenesis and metastasis in tumor-bearing mice. Although researchers have uncovered pleiotropic role of wogonin in the regulation of different oncogenic signaling cascades but there are visible knowledge gaps in our understanding related to regulation of non-coding RNAs by wogonin. Future studies must converge on the unraveling of additional drug targets for wogonin to achieve a fuller and realistic understanding of the chemopreventive properties of wogonin.
AtıfScopus5WoS6İncele - MakaleYalnız künye2021Scopus SJRQ2Graphene-reinforced potato starch composite films: Improvement of mechanical, barrier and electrical properties
Gürler, Nedim; Torğut, Gülben
In this study, PSG composite films were prepared by casting method by adding graphene (G) to glycerol plasticized potato starch (PS) films. The structure and properties of the composite films were investigated attenuated total reflectance Fourier transform infrared (ATR-FTIR), X-ray analysis (XRD), and swelling capacity, total soluble matter, transparency, tensile strength, and electrical conductivity. When the G content of PSG composite films increased from 0% to 1%, tensile strength increased from 1.035 MPa to 1.681 MPa, but decreased to 1.175 MPa in composite films containing 2% G. It also increased electrical conductivity when the G concentration increased. Also, the G layers are among the PS films and their swelling and solubility properties are reduced. With increased G concentration, the light transmittance decreased and the films were more opaque. These improvements can refer to the interface interaction between PS and G.
AtıfScopus43WoS35OpenAlex39İncele - MakaleAçık Erişim2021Scopus SJRQ3Lutein/zeaxanthin isomers regulate neurotrophic factors and synaptic plasticity in trained rats
Orhan, Cemal; Erten, Füsun; Er, Beşir; Tuzcu, Mehmet; Şahin, Nurhan; Durmaz Kurşun, Öznur Ece; Juturu, Vijaya; Şahin, Kazim
Background/aim: This study was conducted to elucidate the effects of lutein/zeaxanthin isomers (L/Zi) on lipid metabolism, oxidative stress, NF-κB/Nrf2 pathways, and synaptic plasticity proteins in trained rats. Materials and methods: Wistar rats were distributed into four groups: 1) control, 2) L/Zi: rats received L/Zi at the dose of 100 mg/kg by oral gavage, 3) exercise, 4) exercise+L/Zi: rats exercised and received L/Zi (100 mg/kg) by oral gavage. The duration of the study was eight weeks. Results: Exercise combined with L/Zi reduced lipid peroxidation and improved antioxidant enzyme activities of muscle and cerebral cortex in rats (p < 0.001). In the Exercise + L/Zi group, muscle and cerebral cortex Nrf2 and HO-1 levels increased, while NF-κB levels decreased (p <0.001). Also, L/Zi improved BDNF, synapsin I, SYP, and GAP-43 levels of the cerebral cortex of trained rats (p < 0.001). The highest levels of BDNF, synapsin SYP, and GAP-43 in the cerebral cortex were determined in the Exercise+L/Zi group. Conclusion: These results suggested that exercise combined with L/Zi supplementation might be effective to reduce neurodegeneration via improving neurotrophic factors and synaptic proteins, and oxidative capacity in the cerebral cortex.
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İncele - MakaleYalnız künye2021Determination of Antioxidant Capacity, Phenolic and Elemental Composition in Syriac (Mardin) Wines by using Chromatographic and Spectrophotometric Methods
Sanyurek, Nesrin Karaca; Ince, Olcay Kaplan; Aydogdu, Burcu; Ince, Muharrem
Free radicals are responsible for many health problems, especially oxidative stress-related diseases. With conscious nutrition and the use of natural antioxidants, it is now possible to cope with these diseases or minimize their effects. The aim of this study was to determine pH, total acidity, total SO2, free SO2, relative SO2, dry matter, density, alcohol content, reducing sugar, ash, CUPRAC, DPPH free radical scavenging capacity, total phenolic content, elemental composition, and some phenolic compounds of Syriac (Mardin) wines. Estimated daily intake (EDI), target hazard quotients (THQ), total target hazard quotients (TTHQ), and relative risk (RR) were calculated, to assess a health risk resulting from regular consumption of Syriac wines. The elements EDI values through consumption of wines were less than the recommended dietary allowance values. Obtained THQ values were less than 1. When the obtained results are compared with the levels set by regulatory authorities, the investigated wine consumption does not pose a toxicological risk based on EDI, THQ, TTHQ, and RR values. In addition, this study showed that the Syriac wine’s antioxidant capacities are high and rich in phenolic compounds and elements.
AtıfScopus1WoS1OpenAlex3İncele - MakaleYalnız künye2021Scopus SJRQ1Experimental design approach for ultra-fast nickel removal by novel bio-nanocomposite material
Ince, Olcay K.; Aydogdu, Burcu; Alp, Hevidar; Ince, Muharrem
In the present study, novel chitosan coated magnetic magnetite (Fe3O4) nanoparticles were successfully biosynthesized from mushroom, Agaricus campestris, extract. The obtained bio-nanocomposite material was used to investigate ultra-fast and highly efficient for removal of Ni2+ ions in a fixed-bed column. Chitosan was treated as polyelectrolyte complex with Fe3O4 nanoparticles and a Fungal Bio-Nanocomposite Material (FBNM) was derived. The FBNM was characterized by using X-Ray Diffractometer (XRD), Scanning Electron Microscopy-Energy Dispersive X-Ray Spectroscopy (SEM-EDS), Fourier Transform Infrared spectra (FTIR) and Thermogravimetric Analysis (TGA) techniques and under varied experimental conditions. The influence of some important operating conditions including pH, flow rate and initial Ni2+ concentration on the uptake of Ni2+ solution was also optimized using a synthetic water sample. A Central Composite Design (CCD) combined with Response Surface Modeling (RSM) was carried out to maximize Ni2+ removal using FBNM for adsorption process. A regression model was derived using CCD to predict the responses and analysis of variance (ANOVA) and lack of fit test was used to check model adequacy. It was observed that the quadratic model, which was controlled and proposed, was originated from experimental design data. The FBNM maximum adsorption capacity was determined as 59.8 mg g−1. Finally, developed method was applied to soft drinks to determine Ni2+ levels. Reusability of FBNM was tested, and the adsorption and desorption capacities were not affected after eight cycles. The paper suggests that the FBNM is a promising recyclable nanoadsorbent for the removal of Ni2+ from various soft drinks.
AtıfScopus11WoS11OpenAlex7İncele - MakaleYalnız künye2021Scopus SJRQ2The assessment of basic blue 41 textile dye decolorisation using the Fenton process: response surface methodology optimisation and toxicity evaluation
Tanyol, Mehtap; Cikcikoglu Yildirim, Nuran; Tatar, Sule; Serdar, Osman; Yildirim, Numan
The biochemical biomarkers (Catalase (CAT), glutathione s-transferase (GST), cytochrome P4501A1 (CYP1A1450) activities and glutathione (GSH), malondialdehyde (MDA) levels) of D. polymorpha exposed to the basic blue 41 (BB41) solutions for 24 and 96 h before and after the Fenton process (FTP) were evaluated to investigate the efficiency of the FTP. The optimum conditions for the removal of BB41 were set using central composite design (CCD), which is a response surface methodology (RSM) module in the Design-Expert® software. The optimal conditions were found to be 27.87 min, 3.49 mg/L, and 0.04 for reaction time, initial BB41 concentration, and Fe2+/H2O2 molar ratio, respectively, resulting in maximum (99%) removal efficiency. After FTP, the MDA and GSH levels decreased significantly during the 24 and 96 h. CAT activities were increased after treatment. No statistically significant changes were observed in the CYP1A1 levels after FTP. GST activities decreased during 24 h but increased during 96 h after FTP. CYP1A1450, catalase, GST activities and MDA, GSH levels of D. polymorpha are useful biomarkers to evaluate the efficiency of FTP. This study suggests that BB41 dye must be further treated after the FTP to minimise the ecotoxicological risk.
AtıfScopus8WoS6OpenAlex8İncele - MakaleAçık Erişim2021Scopus SJRQ3Determination of fatty acids in Allium tuncelianum (Tunceli garlic) by gas chromatography with flame ionization detection (GC–FID)
Ugur, Yilmaz; Karaaslan-Ayhan, Nagihan; Icen, M. Sina; Bicim, Tulin; Erdogan, Selim; Yaman, Mehmet
Garlic has an important place in daily nutrition. It is consumed by people because of its antimicrobial, antibacterial, and antioxidant properties, and it is also known to be good for many diseases. Along with these properties of garlic, its fatty acid content is also important. The goal of this study is to determine the fatty acids in Allium tuncelianum (Tunceli garlic), which grows naturally in Tunceli, Turkey, by gas chromatography with flame ionization detection (GC–FID). Fifteen of 37 fatty acids studied were detected in Allium tuncelianum, and the primary fatty acids in the sample extracts were determined to be the polyunsaturated fatty acid (PUFA) linoleic acid (C18:2n6c, 41.595%) and the monounsaturated fatty acid (MUFA) oleic acid (C18:1n9c, 33.302%). Small quantities of saturated fatty acids (SAFAs) were also present, including palmitic acid (C16:0, 11.739%), henoicosanoic acid (C21:0, 6.946%), and stearic acid (C18:0, 2.362%).
AtıfScopus12WoS8OpenAlex11İncele - MakaleAçık Erişim2021Scopus SJRQ3Determination of anthocyanins and anthocyanidins in the wild grape (Vitis sylvestris Gmelin) by high-performance liquid chromatography-diode array detection (HPLC-DAD)
Karaaslan-Ayhan, Nagihan; Yaman, Mehmet
The determination of anthocyanins and anthocyanidins in wild grapes (Vitis sylvestris Gmelin) from Tunceli-Turkey are reported together with the influence of the extraction conditions on the results. Representative sets of anthocyanins (delphinidin-3-o-glucoside, cyanidin-3-o-glucoside, pelargonidin-3-o-glucoside, malvidin-3-o-glucoside) and anthocyanidins (delphinidin, cyanidin, pelargonidin, malvidin) were simultaneously determined by high performance liquid chromatography with diode array detection (HPLC-DAD). The extraction conditions including the solvent type, extraction time and liquid:solid ratio (v:w) were optimized. The anthocyanin and anthocyanidin contents changed significantly depending on the extraction conditions. Malvidin-3-o-glucoside was identified to be the primary compound.
AtıfScopus10WoS8OpenAlex11İncele - MakaleYalnız künye2021Scopus SJRQ1Evaluation of the efficiency of chlorpyrifos-ethyl remediation by Methylobacterium radiotolerans and Microbacterium arthrosphaerae using response of some biochemical biomarkers
Onder Erguven, Gokhan; Tatar, Şule; Serdar, Osman; Yildirim, Nuran Cikcikoglu
This study reveals out detoxifying and antioxidant enzyme response of Gammarus pulex exposed/polluted to chlorpyrifos-ethyl insecticide before and after biodegradation/bioremediation by Methylobacterium radiotolerans and Microbacterium arthrosphaerae. Cytochrome P450 1A1, glutathione S-transferase, catalase, and superoxide dismutase activities in G. pulex exposed to chlorpyrifos-ethyl before and after bioremediation/biodegradation by these two bacteria during 24 and 96 h tested by using commercial ELISA kits. The activity of catalase enzyme was decreased depending on chlorpyrifos-ethyl before and after bioremediation/biodegradation the enzyme activity was increased repeatedly. Superoxide dismutase activity level increased after chlorpyrifos-ethyl exposure in 96 h (p > 0.05). Following bioremediation, superoxide dismutase enzyme activity decreased again during 24 h (p > 0.05) and increased during 96 h (p < 0.05). Statistical differences were not found in cytochrome P450 1A1 enzyme activity before and after the process (p > 0.05). No significant differences were determined during the activity of glutathione S-transferase in 24 h (p > 0.05). The activities of glutathione S-transferase were increased after exposure of chlorpyrifos-ethyl during 96 h. After bioremediation; the activity of glutathione S-transferase increased even more (p < 0.05). The results determined that activities of G. pulex at superoxide dismutase, catalase, and glutathione S-transferase are common biomarkers for revealing out the efficiency of bioremediation of chlorpyrifos-ethyl with these two types of soil bacteria. [Figure not available: see fulltext.]
AtıfScopus15WoS14OpenAlex16İncele - MakaleAçık Erişim2021Scopus SJRQ2Metaheuristic Approaches Integrated with ANN in Forecasting Daily Emergency Department Visits
Pekel, Engin; Gul, Muhammet; Celik, Erkan; Yousefi, Samuel
The overall service quality level of Emergency Departments (EDs) can be improved by accurate forecasting of patient visits. Accordingly, this study aims to evaluate the use of three metaheuristic approaches integrated with Artificial Neural Network (ANN) in forecasting daily ED visits. To do this, five performance measures are used for evaluating the accuracy of the proposed approaches, including Bayesian ANN, Genetic Algorithm-based ANN (GA-ANN), and Particle Swarm Optimization algorithm-based ANN (PSO-ANN). The outputs of this study show that the PSO-ANN model provides the most dominant performance in both the training and testing process. The lowest error is obtained with a mean absolute percentage error (MAPE) of 6.3%, Mean Absolute Error (MAE) of 42.797, Mean Squared Error (MSE) of 2499.340, Root Mean Square Error (RMSE) of 49.933, and R-squared (R2) of 0.824 on the training dataset. The lowest error with an MAPE of 6.0%, MAE of 40.888, MSE of 2839.998, RMSE of 53.292, and R2 of 0.791 is also obtained on the testing process.
AtıfScopus7WoS5OpenAlex7İncele - MakaleYalnız künye2021Scopus SJRQ4Balneotherapy Features of Natural Thermal Source from Pertek (Turkey-Tunceli) Due to Its Some Chemical, Radioactivity and Biological Parameters
Sönmez, Pinar Erecevit
It can also be defined as a discipline that reviews the factors of balneology or hydrotherapy, which are alternative treatment methods for public health, from chemical, biological and medical aspects. In this study, it was aimed to investigate whether the underground waters in the Pertek district of Tunceli province are suitable for balneology. Chemical, radioactivity analysis, microbiological quality, antimicrobial activities were determined in relation to natural groundwater and its ability to be a natural healing source was investigated. When the chemical content is examined, it was determined to be bromide amount is 0.24 mg / L, Iodine (I); 1.9 mg / L, sulfur (S); 0.02 mg / L, boron (B): 2676 µg / L, silicium (Si); 1.9 mg / L. With respect to the results, thermal water has the feature to be used in balneolotherapy. According to the results of the radioactivity analysis, alpha (α) is 0.15 Bq / L; Beta (β) is <0.30 Bq / L and radon (Rn) is <13.4 Bq / L tritium (T) content is <10 Bq / L (<83.33 TB) and it is included in both mineral and young water group. This ground water and they comply with the standards in terms of microbiology (Total bacteria, coliform, Escherichia coli). Its antibacterial, antifungal and antidermatophyte properties prove to be a healing source. We confirmed the effectiveness of this healing water to both protect and promote human health as a drinking cure and reach the newest and most effective treatment modalities by using related water in Health and Thermal Tourism.
- MakaleYayıncıda açık erişim2021Scopus SJRQ4Effects of magnesium biotinate supplementation on serum insulin, glucose and lipid parameters along with liver protein levels of lipid metabolism in rats
Sahin, Kazim; Orhan, Cemal; Kucuk, Osman; Erten, Fusun; Tuzcu, Mehmet; Sahin, Nurhan; Ojalvo, Sara Perez; Komorowski, James Richard
The objective of this study was to investigate the effects of a novel form of biotin (magnesium biotinate) on serum glucose, lipid profile, and hepatic lipid metabolism-related protein levels in rats. Forty-two rats were divided into six groups and fed a standard diet-based egg white powdered diet supplemented with either d-biotin at 0.01, 1, or 100 mg/kg BW or magnesium biotinate at 0.01, 1, or 100 mg/kg BW for 35 days. Neither form of biotin influenced (p > 0.05) serum glucose or insulin concentrations. Serum total cholesterol and triglyceride decreased with biotin from both sources (p < 0.05). Concentrations were lower with magnesium biotinate when comparing the 1 mg/kg dose (p < 0.05). Serum, liver, and brain biotin and liver cyclic guanosine monophosphate (cGMP) concentrations were greater when rats were treated with magnesium biotinate versus d-biotin, particularly when comparing the 1 and 100 mg/kg dose groups (p < 0.05). Both biotin forms decreased the liver SREBP-1c and FAS and increased AMPK-a1, ACC-1, ACC-2, PCC, and MCC levels (p < 0.05). The magnitudes of responses were more emphasized with magnesium biotinate. Magnesium biotinate, compared with a commercial d-biotin, is more effective in reducing serum lipid concentrations and regulating protein levels of lipid metabolism-related biomarkers.
AtıfScopus5WoS5OpenAlex5İncele - MakaleAçık Erişim2021Scopus SJRQ2The effect of nurses' compassion on burnout: A cross-sectional study
Kaplan Serin, Emine; Özdemir, Ahmet; Işik, Kevser
Purpose: This study was carried out to determine the effect of nurses' compassion on burnout. Design and Methods: This cross-sectional descriptive study was conducted with 177 nurses. An introductory information form, the compassion scale and the Maslach burnout inventory were used as the data collection tools. Frequency, percentage, t test, analysis of variance, Kruskal-Wallis, correlation, and regression were used in the analysis of the data. Findings: The majority of the participants were determined to be female, married and university graduates. It was determined that there was a significant negative relationship between the nurses' sense of compassion and burnout levels, and burnout decreased as compassion increased. Practical Implication: Burnout and compassion fatigue may lead to inadequate care for the patient. This situation will negatively influence nurses' care quality.
AtıfScopus13WoS10OpenAlex14İncele - MakaleYalnız künye2021Scopus SJRQ2Infrared drying of dill leaves: Drying characteristics, temperature distributions, performance analyses and colour changes
Tezcan, Derya; Sabancı, Serdal; Cevik, Mutlu; Cokgezme, Omer Faruk; Icier, Filiz
Thin-layer drying behaviour of dill leaves samples under three different infrared radiation power intensities was investigated. Diffusion Approach was found to be the best model that describes the drying behaviour of dill leaves. Effective diffusivity values were 6.97 × 10−9, 6.84 × 10−9 and 8.96 × 10−9 m2/s for power intensities of 1790, 1970 and 2070 W/m2, respectively. According to the first and second law efficiencies, the infrared drying system was more efficient at higher power intensities (p < 0.05). However, the total colour change was maximum at the highest power intensity. For the investigated infrared drying conditions, 1970 W/m2 was recommended as the best-infrared power intensity applied for drying of dill leaves by taking into account both performance analyses and quality changes.
AtıfScopus40WoS34OpenAlex44İncele