Sürdürülebilir Kalkınma Amaçları

• 4

Yazarlar

• Adigüzel, Ragip(2)
• Buldurun, Kenan(2)
• Körkoca, Hanifi(2)
• Turan, Nevin(2)
• Çolak, Naki(2)
• Aksakal, B.(1)
• Aksakal, Bunyamin(1)
• Aksakal, Bünyamin(1)
• Aslan, N.(1)
• Aslan, Naim(1)
• Ayhan, Nagihan Karaaslan(1)
• Bekler, F. Matpan(1)
• Cetin, Fadime(1)
• Cihangir, Salih(1)
• Dikici, A.(1)
• Fidan, F.(1)
• Gündüz, Bayram(1)
• Karadogan, S.A.(1)
• Karaman, Altuğ(1)
• Say, Yakup(1)
• Sezek, S.(1)
• Sinirlioglu, Zeynep A.(1)
• Torğut, Gülben(1)
• Yazdıç, Ferit Can(1)
• Yildirim, N.(1)
• Yildirim, N. Cikcikoglu(1)
• Yilmazer, Y.(1)
• Yilmazer, Yasemin(1)

• MakaleAçık Erişim2024Scopus SJRQ2/r/munzur/1830
  The influence of cold rolling and hydroxyapatite coating on the mechanostructure, corrosion resistance, cell viability, and antibacterial activity of ZnCu biodegradable implants

  Aksakal, B.; Karadogan, S.A.; Aslan, N.; Fidan, F.; Yilmazer, Y.; Sezek, S.

  Zinc (Zn) and its alloys exhibit great potential for utilization in biodegradable bone implants. Zn-1Cu biodegradable alloy was produced and were cold rolled at two different deformation rates of 47 and 61%. The samples have been bioceramic coated with the sol–gel method and microstructure-mechanical property changes, corrosion behavior and biocompatibility of the samples were investigated. They were characterized by Optical, SEM, XRD and wettability analysis. The rolled samples showed a significant increase in hardness when compared to the non-rolled samples. The unrolled and 47% rolled samples showed better corrosion resistance compared to 61% rolled samples. Antibacterial effects of the base and sol–gel-coated groups showed higher cell viability ratios than the uncoated groups. Cell viability increased significantly in 47% of the rolled samples after 24, 48, and 72 h, however decreased by up to 70% in 61% of the rolled samples. Graphical abstract: (Figure presented.).

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  AtıfScopus2·WoS2·OpenAlex2

  İncele
• MakaleYalnız künye2023Scopus SJRQ2/r/munzur/2104
  Antibacterial activity of novel synthesized chitosan-graft-poly(N-tertiary butylacrylamide)/neodymium composites for biomedical application

  Yazdıç, Ferit Can; Karaman, Altuğ; Torğut, Gülben; Ayhan, Nagihan Karaaslan

  In this present study, composites of chitosan-graft-poly(N-tertiary butylacrylamide) (CH-graft-poly(N‑tert‑BAAm)) copolymer, with Neodymium (Nd), an important rare earth element, were prepared by precipitation technique. Nd was successfully incorporated into the polymer of different weight percentages (0.5%, 1%, and 2%) without any degradation. The effect of neodymium additives on the structural, morphological, and antibacterial activities against gram-positive bacteria and gram-negative bacteria of the polymer was analyzed using various instrument techniques. X-ray diffraction (XRD) results together with Fourier Transform Infrared (FT-IR), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS) studies confirmed the morphology of Nd-doped CH-graft-poly(N‑tert‑BAAm) composites without any other impurities. The antibacterial effect of Nd was studied by adding it to the copolymer in a weight ratio of 0.5%–2%. The antibacterial effect of neodymium concentration on four different strains of bacteria was investigated: Escherichia coli (ATCC 25922) (E. coli), Pseudomonas aeruginosa (DSM 50071) (P. aeruginosa), Bacillus subtilis (DSM 1971) (B. subtilis), and Staphylococcus aureus subsp. aureus (ATCC 25923) (S. aureus). The antibacterial activities of the obtained composites were determined using the Agar Well Diffusion Assay Method. Experimental results show that Nd binds well to CH-graft-poly(N‑tert‑BAAm). Activity against E. coli, P. aeruginosa, B. subtilis, and S. aureus subsp. aureus creates a potential for pharmaceutical and biomedical applications.

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  AtıfScopus8·WoS7·OpenAlex8

  İncele
• MakaleAçık Erişim2023Scopus SJRQ2/r/munzur/1597
  ZrN and ta-C coatings on titanium for biomedical applications: Improved adhesion, corrosion, antibacterial activity, and cytotoxicity properties

  Aslan, Naim; Aksakal, Bünyamin; Cihangir, Salih; Cetin, Fadime; Yilmazer, Yasemin

  Commercially pure titanium (CP-Ti) is extensively used in biomedical applications. However, numerous qualities, including mechanical strength, corrosion resistance, and wear resistance, must be established for long-term performance as an implant material. This study investigates the enhancement of surface properties of CP-Ti through physical vapor deposition (PVD) with ZrN and ta-C (tetrahedral amorphous carbon). Among the coatings, ZrN revealed best overall results, such as adhesion, corrosion, microhardness, and wettability, excluding cell viability when compared to ta-C. E. coli and S. aureus were employed for antibacterial activity and MTS cell viability experiments. Compared to α-titanium, hardness tests revealed 91% increase in ZrN coating, and %22 increase in ta-C coating. Super-hydrophobicity and excellent antibacterial activity were found for ZrN coatings in comparison to ta-C. These findings emphasize the potential of ZrN and ta-C coatings to improve the surface properties of titanium, encouraging it to be used in biomedical devices. Graphical abstract: [Figure not available: see fulltext.].

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  AtıfScopus16·WoS16·OpenAlex19

  İncele
• MakaleYalnız künye2022Scopus SJRQ2/r/munzur/2576
  Silver/selenium/chitosan co-substituted bioceramic coatings of Ni–Ti alloy: Antibacterial efficiency and cell viability

  Say, Yakup; Aksakal, Bunyamin; Sinirlioglu, Zeynep A.

  The effects of silver (Ag), selenium (Se), and chitosan (Cht) additives on the antibacterial activity and cell viability of NiTi were investigated. Three different hydroxyapatite (HA)-based bioceramic coatings to improve the antibacterial activity and cell viability of NiTi; HA, HA/Ag, and HA/Se–Cht were applied to NiTi substrates by a sol–gel method. The coated samples were characterized by scanning electron microscopy–electron-dispersive spectroscopy and X-ray diffraction and surface hardnesses were measured. The antimicrobial efficiency of the coatings and uncoated surfaces were tested against Escherichia coli-JM 103 and Staphylococcus aureus-ATCC29293. In vitro cell–material interactions using Saos-2 osteoblast cells were characterized by a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mitochondrial activity test) assay for cell viability. A homogeneous, crack-free, and porous surface morphology is achieved in coatings. It has been shown that the Se–Cht additives did not have a significant effect on the surface hardness of the HA coating, but the Ag additive increased the hardness. Through in vitro antibacterial activity and cell viability tests, it was shown that Ag additive to bioceramic coatings significantly increased (p <.05) antibacterial properties but caused a decrease in cell viability. However, although Se–Cht additives did not have a significant effect on antibacterial properties (p <.05), it was observed that they increased cell viability.

  • 
  AtıfScopus8·WoS8·OpenAlex2

  İncele
• MakaleAçık Erişim2015Scopus SJRQ2/r/munzur/4423
  Synthesis, Structural Characterization and Biological Activity of Novel Cyclohexane-1,3-dione Ligands and Their Metal Complexes

  Turan, Nevin; Körkoca, Hanifi; Adigüzel, Ragip; Çolak, Naki; Buldurun, Kenan

  Some new Zn(II) and Cu(II) complexes [Cu(L-1)(OAc)(2)].H2O, [Cu(L-1)(NO3)H2O].NO3.3.5H(2)O, [Zn(L-1)(NO3)(2)].4.5H(2)O, [Zn(L-1)(OAc)(2)(H2O)(2)].3H(2)O, [Cu-2(L-2)(OAc)(4)].2H(2)O.2DMF, [Cu(L-2)(2)].2NO(3).1.5DMF.H2O, [Zn(L-2)(2)(NO3)(2)].DMF and [Zn-2(L-2)(OAc)(4)(H2O)(4)].5H(2)O; L-1 = 2-[2-(2-methoxyphenyl)hydrazono]cyclohexane-1,3-dione and L-2 = 2-[2-(3-nitrophenyl)hydrazono]cyclohexane-1,3-dione were synthesized and characterized by IR, H-1-NMR,C-13-NMR and ultraviolet (UV-Vis.) spectroscopy, elemental analysis, magnetic susceptibility, mass spectrometry and thermogravimetry-differential thermal analysis (TGA-DTA). The synthesized ligands and their complexes were tested for antibacterial activity against Escherichia coli ATCC 25922, Enterococcus faecalis ATCC 29212, Staphylococcus aureus ATCC 25923, and Salmonella typhimurium CCM 583. Some of complexes showed medium-level antibacterial activity against the test bacteria compared with ampicillin.

  AtıfWoS20·OpenAlex18

  İncele
• MakaleYalnız künye2014Scopus SJRQ3/r/munzur/4216
  Study of Structure and Spectral Characteristics of the Zinc(II) and Copper(II) Complexes With 5,5-Dimethyl-2-(2-(3-nitrophenyl) hydrazono)cyclohexane-1,3-dione and Their Effects on Optical Properties and the Developing of the Energy Band Gap and Investigation of Antibacterial Activity

  Turan, Nevin; Gündüz, Bayram; Körkoca, Hanifi; Adigüzel, Ragip; Çolak, Naki; Buldurun, Kenan

  A new chelating ligand, 5,5-dimethyl-2-(2-(3-nitrophenyl)hydrazono)cyclohexane-1,3-dione (L), and four transition metal complexes were synthesized. The ligand and its complexes were characterized by IR, H-1 and C-13-NMR spectra, elemental analyses, magnetic susceptibility, mass spectra, UV-Vis. and thermogravimetry-differential thermal analysis (TGA-DTA). The metal complexes showed different geometric structures. Antibacterial tests of the ligand and complexes were also done. The Zn(II) complexes showed antibacterial activity against Staphylococcus aureus ATCC-25923 at middle level. The optical properties of the ligand and its complexes were extensively investigated by optical measurements. The average transmittance value of the ligand was the highest value, while the average transmittance value of the [CuL2(NO3)(2)]center dot 6H(2)O complex was the lowest value. The optical band gap of the ligand, [(Zn)(2)L(OH)(4)]center dot 2DMF, [ZnL(NO3)(2)(H2O)(2)]center dot 5H(2)O, [CuL2(OAc)]center dot OAc center dot 3.5H(2)O and [CuL2(NO3)(2)]center dot 6H(2)O complexes were calculated and 3.121 eV, 2.180 eV, 1.551 eV, 2.489 eV and 1.556 eV values were found, respectively. The complexes decreased the optical band gap of the ligand. The optical band gap value of the [ZnL(NO3)(2)(H2O)(2)]center dot 5H(2)O complex is the lowest value. The optical band gap value of the ligand is the highest value. The complexes decrease the angle of incidence of the ligand, while complexes increase the angle of refraction of the ligand. The electric susceptibility of the ligand decreases with its complexes.

  AtıfWoS28

  İncele
• MakaleYalnız künye2010Scopus SJRQ2/r/munzur/4295
  IN VITRO ANTIMICROBIAL EVALUATION OF COMMERCIAL TEA EXTRACTS AGAINST SOME PATHOGEN FUNGI AND BACTERIA

  Yildirim, N.; Bekler, F. Matpan; Yildirim, N. Cikcikoglu; Dikici, A.

  The in vitro antimicrobial activity of crude ethanol, methanol, hexane and aqueous extracts of commercial tea types such as fennel (Foeniculum sp.), senna (Cassia sp.), basilrosemary (Ocimum sp.-Rosmarinus sp), daisy (Bellis sp.) and sage (Salvia sp) against pathogen fungi (Colletotrichum coccodes, Epicoccum nigrum, Scopulariopsis brevicaulis) and foodborne pathogen bacteria (Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 25923, Bacillus cereus, Klebsiella pneumoniae, Enterobacter sp.) were investigated with disk diffusion method. Senna (Cassia sp.) exhibed the most effective antimicrobial activity in both ethanolic and methanolic extracts. The best antimicrobial effect (30.6 mm) against E. nigrium was seen in methanolic senna (Cassia sp.) extract. The results of the study indicate that commercial tea types have showed various levels of antimicrobial activity depend on the type of solvent used in the extraction procedure.

  AtıfWoS5

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