Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Gul, Muhammet(86)
- Güler, Ömer(69)
- Akkurt, Nevzat(68)
- Baskonus, Haci Mehmet(53)
- Tekin, H.O.(52)
- Bulut, Hasan(50)
- ALMisned, Ghada(49)
- Serdar, Osman(43)
- Yucesan, Melih(43)
- Paksoy, Mehmet Yavuz(42)
- Yildirim, Numan(41)
- Zengin, Gokhan(40)
- Yildirim, Nuran Cikcikoglu(39)
- Ince, Muharrem(37)
- Kocabaş, Mehmet(37)
- Celik, Erkan(35)
- Benzer, Fulya(33)
- Sulaiman, Tukur Abdulkadir(29)
- Aslan, Naim(27)
- Can, Erkan(27)
- Kutlu, Banu(27)
- Kök, Mediha(27)
- Tanyol, Mehtap(27)
- Danabas, Durali(26)
- Kutluyer, Filiz(26)
- Özkul, İskender(26)
- Ates, Mehmet(25)
- Yildirim, Ozal(25)
- Onat, Onur(23)
- Topal, Murat(23)
- Demir, Veysel(22)
- Erten, Fusun(22)
- Guler, Omer(22)
- Say, Yakup(22)
- Yaman, Mehmet(22)
- Alataş, Mevlüt(21)
- Güler, Seval Hale(21)
- Çimen, Okay(21)
- Baykal, Duygu Sen(20)
- Mete, Suleyman(20)
Yayınlar
- MakaleYalnız künye2010Scopus SJRQ3The Biochemical Parameters Having Economic Importance in Sheep and Fish Meats
Kayim, M.
In this study, 10 meat samples from fish (Trachurus trachurus L. 1758) and sheep (Akkaraman) were used. In the experiment, the used fish meat was a total body meat. However, the sheep longissimus muscle (lean) from 6th rib cut was sampled for determination of chemical components. The concentrations of total fat were lower (p < 0.01) for fish than sheep. However, the concentrations of pH were also lower (p < 0.05) for sheep material. There were no effects of animal species on the moisture concentrations. The rates of ash were lower (p < 0.01) for sheep group. The pH concentrations close to neutral in meat from fish may be advantage for eating quality. However, this pH level is disadvantage for shelf life of product. However, the high amounts of fat in the sheep meats may have a negative effect upon consumer's preference and health.
- MakaleYayıncıda açık erişim2010Scopus SJRQ3The Investigation of Quality Changes in Marinades Obtained from Frozen African Catfish (Clarias gariepinus, B., 1822)
Kaya, Gulderen Kurt; Gozu, Buket Busra; Basturk, Ozden
In this study, it is aimed to investigate the suitability of African catfish (Clarias gariepinus, B.,1822) caught intensively, especially in Mersin-Silifke for marinating and determine its shelf life. After their heads and tails were cut off and they were eviscerated first and then washed and drained of the water, the samples were put into plastic refrigerator bags and kept at -18 degrees C for 3 months. At the end of 3 months, the frozen samples were defrosted and boiled in boiling water for 5 min. They were put in brine after cooling and preserved at 4 +/- 1 degrees C. In the raw material, raw protein, lipid, moisture, raw ash analyses of the samples kept frozen for 3 months and the marinated samples were done in order to monitor the changes in the food composition at 3 month intervals and Thiobarbituric Acid number (TBA), Total Volatile Basic-Nitrogen (TVB-N), peroxide number, pH and sensory analyses were done in order to monitor the changes in chemical quality.
AtıfWoS1
İncele - MakaleYalnız künye2010Scopus SJRQ3The Suitable for Aquaculture Water Source Research and Water Quality Parameters in the Some Cities in the Gap Regions
Ural, Mesut; Memisoglu, Erdem; Ornekci, G. Nedim
In the culturel production aquaculture, first physical and chemical have suitable for flow owner a water source and ecological factor minimal level effection an appropriate to occupy a place. In this research Adiyaman, Diyarbakir, Gaziantep, Kilis and Sanliurfa cities were 25 L/sn and have more flow stream, river and source water for aquaculture production water source and in order to production appropriate to occupt a place.
- MakaleYalnız künye2010Scopus SJRQ3Effect of Potassium Sorbate on Some Microbiological Properties of Cokelek Stored at Different Temperatures
Öksüztepe, Gulsum; Ilhak, O. Irfan; Dikici, Abdullah; Çalicioglu, Mehmet; Patir, Bahri
In this study, the effect of potassium sorbate at 0.01%, 0.05% and 0.1% on the some microbiological (total aerobic mesophilic bacteria-IAMB, coliform bacteria, Lactobacillus-Leuconostoc-Pediococcus, Stapylococcus-Micrococcus. enterococcus and yeast-mold) and chemical (pH, acidity) properties of cokelek stored at 4 +/- 1 degrees C or 22 +/- 1 degrees C was investigated. It was seen that adding potassium sorbate at 0.01%, 0.05% and 0.1% to cokelek did not have an effect on numbers of TAMB, coliform bacteria, lactobacillus- leuconostoc- pediococcus, staphylococcus-micrococcus in cokelek stored at both 4 +/- 1 degrees C and 22 +/- 1 degrees C (P>0.05). However, adding potassium sorbate at 0.05% and 0.1% to cokelek had an effect on numbers of enterococci and yeast-mold in cokelek stored at 4 +/- 1 degrees C (P<0.05). It was also not observed significant difference in pH and acidity levels between control group and treatment groups containing potassium sorbate during storage period (P>0.05).
AtıfWoS5İncele - MakaleYalnız künye2010Scopus SJRQ3Presence of E. coli O157:H7 in Cakes Marketed in Elazig
Öksüztepe, Gulsum; Patir, Bahri; Çalicioglu, Mehmet; Ilhak, O. Irgan; Dikici, Abdullah
The present study was undertaken to investigate the presence of Escherichia coli O157:H7 in cakes (plain, with cacao, with fruit) marketed in Elazig. A total of 200 cake samples as 100 plain, 50 with cacao, and 50 with fruit were analysed. Following the enrichment, the samples were plated on to CT-SMAC agar. A total of 208 typical colonies (colourless) as 138 colonies from 65 plain cakes, 25 colonies from 8 cakes with cacao, and 45 colonies from 19 cakes with fruit were isolated. These colonies were subjected to further analysis given in the materials and methods section for identification of serotype O157:H7 of E. coli. However, no colonies representing E. coli O157 were detected in any of the samples. Therefore, analysis was not proceeded for determining H7 in any of the isolates. E. coli O157:H7 was not detected in any of the cake samples analyzed. Although this finding is a good news for public health, considering other pathogens, which may exist in cakes, it is concluded and reemphasized that strict hygienic practices should be applied at every stage of cake production.
AtıfWoS2İncele - MakaleAçık Erişim2010Scopus SJRQ3Effects of cypermethrin on antioxidant status, oxidative stress biomarkers, behavior, and mortality in the freshwater mussel Unio elongatulus eucirrus
Köprücü, Kenan; Yonar, Serpil Mise; Seker, Engin
In this study, the effects of cypermethrin on antioxidant status, oxidative stress biomarkers, behavior, and mortality in the freshwater mussel Unto elongatulus eucirrus were examined. Cypermethrin was applied at concentrations of 5, 10, 20, 40, 80, and 160 mu g/L, for 1, 24, 48, 72, and 96 h. With increasing cypermethrin concentrations, the mussels showed significantly (P < 0.05) increased lipid peroxidation (MDA), which might be associated with decreased levels of reduced glutathione (GSH) and catalase (CAT) activity in the digestive glands and gills of the mussels. Negative correlations were observed between the MDA and the GSH and CAT levels after cypermethrin exposure, indicating a protective role of GSH and CAT against lipid peroxidation, and suggesting the use of these antioxidants as a potential biomarker of toxicity associated with contaminant exposure in freshwater mussels. In addition, at 5 mu g/L, cypermethrin had no effect on the duration of the active and rest periods. All higher concentrations caused inhibition of the filtration activity by reducing the active periods and lengthening the rest periods. The active periods shortened as the cypermethrin concentrations increased, the reduction being 90% of the control at 160 mu g/L. Rest periods were longest (237% longer than the control) at 160 mu g/L. The 48, 72, and 96 h LC50 values of cypermethrin for mussels were determined as 96.50, 77.96, and 59.20 mu g/L, respectively (P < 0.05). The results indicate that the insecticide cypermethrin has a harmful effect not only on nontarget aquatic arthropods and fish, but also on mollusks, although the sensitivity of mussels is less than that of fish. Being a general toxicant for aquatic life, cypermethrin should be used with great caution in agriculture to protect natural waters from contamination.
AtıfWoS34İncele - MakaleYalnız künye2010Scopus SJRQ3Age Determination Technique According to the Calcium Accumulation in Bony Structures of Capoeta umbla (Heckel, 1843)
Calta, Metin; Sen, Dursun; Aydin, Rahmi; Koprucu, Kenan; Canpolat, Ozgur; Coban, Mehmet Zulfu
In this study, the ages of individuals belonging to Capoeta umbla (Heckel, 1843) populations obtained from Keban Dam lake and Hazar lake were determined from 5 different bony structures and the level of calcium mineral of each bony structure was measured by atomic absorption spectrophotometer The results were compared between populations of Keban Dam lake and Hazar lake In addition, the determined calcium element was statistically examined according to age, length and weight of fishes The relationships between accumulation of calcium in some bony structures and fish size (both length and weight) and age were found insignificant (p>0 05) However, the best relationships between calcium accumulation and fish size and age were found in vertebra, otolith and dorsal fin ray In conclusion, although there were some differences of calcium accumulation in the same bony structures of fishes obtained from Keban Dam lake and Hazar lake in general there were similarities In addition, the accumulation of calcium on some bony structures was observed to increase with the increasing of age, length and weight of fishes but these Increases were not statistically important
AtıfWoS1İncele - MakaleAçık Erişim2010Scopus SJRQ2The Nature of the Crustal Structure of the Eastern Anatolian Plateau, Turkey
Yilmaz, Ali; Yilmaz, Huseyin; Kaya, Cemal; Boztug, Durmus
The Eastern Anatolian Plateau (EAP) of Turkey, with an elevation ranging from 1700 to 2000 m, is located between the Eastern Pontide Arc to the north and the Arabian Platform to the south. In this region, pre-Maastrichtian tectonic units representing the crust crop out in only a few localities. As they are covered by Maastrichtian-Quaternary rock units, it is difficult to study the nature and mutual relationships of these pre-Maastrichtian tectonic units. The palaeotectonic units of the EAP comprise two different levels in the present study: (1) The lower level consists of platform-type carbonates and their metamorphic equivalents. These units may represent the Taurus Platform and its metamorphic equivalents. (2) The upper level consists of an ophiolitic-melange prism which is made up mainly of oceanic crust; the prism comprises a complex of ophiolite, ophiolitic melange, and fore-arc deposits. This upper unit represents a subduction-accretion prism and may have originated partly from the North Anatolian Suture to the north, and partly from the South-eastern Anatolian Suture to the south. Continental crustal rocks were thrust over by the ophiolitic melange prism; thus outcrops of them are scarce in the region as they are exposed in tectonic windows through the ophiolitic thrust sheets. The pre-Maastrichtian tectonic units of the EAP are blanketed by Maastrichtian to Quaternary volcanic and sedimentary rock units; these sequences include successive transgressive and regressive intervals and overlie the palaeotectonic units along a pronounced unconformity. Olistostromal units are abundant in the Eocene sedimentary units and were derived from the ophiolites and ophiolitic melange. The Maastrichtian-Quaternary cover is made up of collisional and post-collisional deposits across the whole region. Although the EAP has been experiencing considerable N-S compression, it has not been affected by significant crustal thickening because of the strike-slip tectonic regime that is dominant in the region. (C) 2010 Lavoisier SAS. All rights reserved
AtıfWoS33OpenAlex28İncele - MakaleYalnız künye2010Scopus SJRQ3Bioconversion Efficiencies of Lignocellulosic Soy Stalk by Pleurotus eryngii Strains
Yildirim, Numan; Yildiz, Abdunnasir
The bioconversion of soy stalk (SS) lignocellulose by three different starins of Pleurotus eryngii from various origins by solid state fermentation was studied during 40 days. The effect of rice bran ratio, 5% or 10% (w/w), on lignin degradation and laccase activity were measured througout the fermentations while, total crude protein and C/N ratio of the remaining substrate were determined at the end of the fermentations. The degradation of lignocellulose was found by the determination of acid soluble lignin (Klason lignin) content. All the strains degraded lignin with different extents. The amount of lignin degradation was decreased by the addition of the higher quantities of rice bran (SS+10% RB). The highest lignin degradation was obtained as 24.43% by P eryngii var. ferulae (E) and the highest protein level was found to be %13.32 by P eryngii (H). We determined that the laccase activity was generally decreased by the addition of the higher quantities of rice bran (10%). Maximum laccase activity (204.39 U/L) was obtained by P. eryngii (E) on SS + 5% RB at the end of the fermentation. This study showed that, after fungal treatment soy stalk can be used as a feed for ruminants with its higher feeding value.
AtıfWoS2OpenAlex1İncele - MakaleYalnız künye2010Scopus SJRQ3The Milk Biochemical Parameters Having Economic Importance in Machine Milked Cows
Tekelioglu, O.; Cimen, M.; Bayril, T.
This research was aimed to investigate the effect of machine milking on milk biochemical components having economic importance. In the experiment, 10 Machine Milked (MM) and 10 suckled + Hand Milked (HM) cows were used. The milk fat rates were lower for MM animals in 1st, 2nd and 4th weeks (p<0.05). Protein and total solid rates of milks were similar for both groups during study. There was found positive correlation between milk fat and total solids (r = 0.53; p<0.05), but there were no significant correlations among other milk parameters. Suckling treatment (in BM group) to increase production of milk with maximum levels of milk fat is essential for achieving the economic benefits. Producers, who utilize the MM system during lactation should expect commercial milk to be low in fat content, which may affect cheese processing characteristics.
AtıfWoS6İncele - MakaleYalnız künye2010Scopus SJRQ3EVALUATION OF THREE STRAINS OF Pleurotus eryngii ISOLATED FROM GEOGRAPHICALLY DIFFERENT REGIONS OF TURKEY FOR THEIR ABILITY TO DECOLORIZE METHYLENE BLUE AND CHRYSTAL VIOLET
Yildirim, Numan; Yildirim, Nuran Cikcikoglu; Yildiz, Abdunnasir
In this study, the ability to decolorize two chemically different synthetic dyes (methylene blue and crystal violet) by Pleurotus eryngii strains collected from geographically different regions of Turkey was evaluated on agar plates in static liquid cultures. For all strains, growth and decolorization halos were determined on malt extract agar plates containing 0.4 and 0.6 g/L of crystal violet (CV) or methylene blue (MB). Each P. eryngii strain showed certain decolorization capacities and was able to decolorize both MB and CV under static liquid culture conditions, but not to the same extent. The presence of the dyes in static liquid culture reduced the biomass production of all strains in comparison with control culture growing in the medium without dyes. In solid medium, a positive correlation was found between growth halo and decolorization halo.
AtıfWoS1İncele - MakaleYalnız künye2010Scopus SJRQ3THE ROLE OF METHYLATED ADRENOMEDULLIN IN ENZYMATIC ANTIOXIDANT DEFENSE RESPONSE TO COLD STRESS
Yildirim, Nuran Cikcikoglu; Yurekli, Muhittin
The aim of our study was to investigate the effects of methylated adrenomedullin (met-AdM) on some antioxidant enzymes, such as catalase (CAT), glutathione peroxidase (GSH-P-X) and superoxide dismutase (SOD) in rat kidney and heart tissues after cold stress treatment. Male Wistar rats were divided into 4 groups (control, met-AdM, cold stress and cold stress + met-AdM treatments). The rats were kept at room temperature, exposed to a 16/8-hours light/dark cycle. The rats were maintained at ad libitum (free) feeding habit. In met-AdM treated group, animals received intraperitoneal injection of met-AdM (2 mg/g body weight) once a day during a week. For the cold stress exposure, the rats were kept in separate cages at 10 degrees C for a week. Control group rats were kept at laboratory conditions. CAT, GSH-P-X and SOD enzyme activities were investigated in kidney and heart tissues. In kidney tissue compared to control, CAT and GSH-P-X enzyme activity was decreased but SOD was increased in met-AdM-treated group. In met-AdM+cold stress group, only the SOD enzyme activity was significantly increased but CAT and GSH-P-X decreased. SOD and GSH-P-X enzyme activities were increased by cold stress but CAT was decreased in kidney. In heart tissue, CAT and GSH-P-X activities were decreased but SOD was increased in met-AdM-treated group compared to control. All enzyme activities were decreased in met-AdM+cold stress group as well as by cold stress in heart, with regard to control. Cold stress can disrupt the balance in an oxidant/antioxidant system and cause oxidative damage to kidney and heart tissues by altering the enzymatic and non-enzymatic antioxidant status. We can suggest that met-AdM has possible roles in regulation of stress but we need further studies revealing responses of met-AdM in different tissues.
AtıfWoS3İncele - MakaleYalnız künye2010Scopus SJRQ3Use of Flame Atomic Absorption Spectrometry in Diagnosis of Cancerous and Non-Cancerous Breast Tissues: Comparison of Metal Concentrations
Kaya, Gokce; Akdeniz, Ismail; Ozcan, Cemile; Kilinc, Ersin; Yaman, Mehmet
- MakaleAçık Erişim2010Scopus SJRQ2A method for designing strong S-Boxes based on chaotic Lorenz system
Özkaynak, Fatih; Özer, Ahmet Bedri
It is important to design cryptographically strong S-Boxes in order to design secure systems. In this study, a strong, chaos-based S-Box design is proposed. Continuous-time Lorenz system is chosen as the chaotic system. Proposed methodology is analyzed and tested for the following criteria: Bijective property, nonlinearity, strict avalanche criterion, output bits independence criterion and equiprobable input/output XOR distribution. The results of the analysis show that the proposed cryptosystem is a highly reliable system suitable for secure communication. (C) 2010 Elsevier B.V. All rights reserved.
AtıfWoS192OpenAlex235İncele - MakaleYalnız künye2010Scopus SJRQ3Disinfection of Gilthead Sea Bream (Sparus aurata), Red Porgy (Pagrus pagrus), and Common Dentex (Dentex dentex) Eggs from Sparidae with Different Disinfectants
Can, Erkan; Saka, Sahin; Firat, Kuersat
The aim of this study is to determine suitable conditions for egg disinfection of gilthead sea bream (Sparus aurata), red porgy (Pagrus pagrus), and common dentex (Dentex dentex) with glutaraldehyde, hydrogen peroxide and iodine. The eggs were disinfected with 200 ppm glutaraldehyde (T= 2, 4, 8, 16 min), 300 ppm hydrogen peroxide and iodine (T= 5, 10, 15, 20 min) at four different contact times. The hatching rate was determined in triplicates for each treatment. Also, bacteria colonies were counted on tryptic soy agar (TSA) and thiosulphate citrate bile salt sucrose agar (TCBS). At the end of the experiment, bacterial load and hatching rate were assessed together. For glutaraldehyde treatment, optimal hatching rates and bacterial colonies were estimated as CT (Disinfectant concentration in mg.l(-1)* exposure time in minute) 800 for sea bream eggs, CT 1600 for red porgy eggs and CT 800-1600 for common dentex eggs. Also, for hydrogen peroxide treatments, they were determined as CT 3000 for sea bream and red porgy and CT 4500 for common dentex. Finally, in iodine treatments, these parameters were measured as CT 4500-6000 for all species' eggs. However, in our study, it is clear that the glutaraldehyde showed the optimum disinfection effect against the microorganisms because the bacteria could be eliminated completely.
AtıfWoS12İncele - MakaleYalnız künye2010Scopus SJRQ3The effects of commercial diets supplemented with mannanoligosaccharide (MOS) and vitamin B12 on the growth and body composition of the shabbout fries (Tor grypus H. 1843)
Atar, Hasan Huseyin; Ates, Mehmet
Four hundred shabbout fries (Tor grypus L. 1758), with average initial weight of 0.95+/-0.02 g and total average length of 4.10+/-0.05 cm, were fed for a period of 90 days commercial feed with addition of mannanoligosaccharide (MOS) and vitamin B-12. The shabbouts were divided into four different groups and fed by different feeds (Control, Group A with MOS, Group B with vitamin B-12, Group C with the combination of MOS + vitamin B-12). The effects of feeding through MOS and vitamin B-12 in different proportions on growth in view of live weight and total length, survival rate, feed conversion, condition factor and protein efficacy were studied. The best growth in view of live weight of 4.51+/-0.16 g and length of 7.71+/-0.08 cm was maintained through vitamin B-12 in Group B. As a consequence, the growth parameters of the shabbout fries fed through commercial feeds with the addition of MOS and vitamin B-12 in different doses under empirical conditions showed affirmative effects on the survival rate, feed assessment, condition factor and protein efficacy.
- MakaleAçık Erişim2010Scopus SJRQ2Flame Atomic Absorption Spectrometric Determination of Pb, Cd, and Cu in Pinus nigra L. and Eriobotrya japonica Leaves Used as Biomonitors in Environmental Pollution
Kaya, Gokce; Ozcan, Cemile; Yaman, Mehmet
The assessment of trace metal pollution in Gaziantep city-Turkey has been studied using plant leaves of Pinus nigra L. and Eriobotrya japonica as biomonitor. The concentrations up to 3,056 mg Pb kg(-1) in the needles of Pinus nigra L., and 367 ng Cd g(-1) in the leaves of Eriobotrya japonica were determined. The observed Cu concentrations were in range of 1.6-7.1 mg kg(-1). The Pb, Cd, and Cu levels in soils were determined to be in the range of 17-602, 0.142-0.656, and 12-38 mg kg(-1), respectively. It was concluded that Pinus nigra L. can be considered as both biomonitor of atmospheric Pb pollution and hyperaccumulator plant.
AtıfWoS41OpenAlex37
İncele - MakaleYalnız künye2010Scopus SJRQ3Synthesis and Structural Characterization of Ni(II), Cu(II), Zn(II) and Cd(II) Complexes of Bis(2-amino-1,3,4-thiadiazole)
Adiguzel, R.; Ergin, Z.; Sekerci, M.
In this study, the ligand bis(2-amino-1,3.4-thiadiazole) (L) has been synthesized by the reactions of oxalic acid with thiosemicarbazide The ligand and Ni(II), Cu(II), Zn(II), Cd(II) complexes have been synthesized and its structures of these compounds have been deter-mined by elemental analysis. spectrometric and TGA/DTA, magnetic susceptibility and molar conductivity measurements. Coordination numbers of monomeric Ni(I I) and Cd(II) complexes are six and four, respectively. The coordination numbers of dimeric Cu(II) and Zn(II) complexes are live and four. From the elemental analysis and mass spectral data, the complexes were pi posed to have the formula[Ni(L)(2)(SO4)H2O]0 5DMF 2H(2)O center dot[Cu(L)(SO4)H2O](2)center dot DMF 2H(2)O, [Zn(L)(NO3)](2) 2NO(3)center dot 2DMF center dot H2O and [Cd(L)(2)] 2NO(3)center dot 1.5DMF center dot H2O. Ni (II) and Cu(II) complexes are paramagnetic and non-electrolytes. The molar conductance data revealed that zinc(II) and cadmium(II) complexes are 1 2 electrolytes.
AtıfWoS5İncele - MakaleYalnız künye2010Scopus SJRQ4Is it Possible to Transform Hatchery-Reared Abnormal Juveniles of Sea Bass (Dicentrarchus labrax L. 1758) into Normal Individuals?
Kayim, M.; Can, E.; Güner, Y.
Lordosis, which is one of the skeletal deformations, was frequently encountered in the culture of sea bass (Dicentrarchus labrax L. 1758) and it affects the biological performance and marketing image of the fish negatively. Thus it causes big economic losses. In larger natural environments, this abnormality in wild-caught individual is rare, whereas the case is the other way round in hatchery-reared sea bass. This problem can be caused by swim bladder malformations, environmental conditions, bacterial factors, water flow rate and swimming activity. However, many researchers reported that all of these factors cause these malformations in different regions of the skeletal system, commonly known as V-shaped curvatures. But in this study, it is not aimed to investigate the possible causes of the observed abnormalities. We focused on whether the abnormal individuals can be transformed into individuals with normal skeletal systems. In this study, a total number of 5636 juvenile individuals (0.09-1.93 g of live weight) were used. Lordosis rates were identified between the days 54 and 110 by randomly taking at least 30 samples from every group on a weekly basis, at triplicate. In this study, 100% of the individuals with this type of deformation were successfully transformed into individuals with the normal skeletal system in a large volume and rectangular ponds with semi-intensive rearing method.
AtıfWoS9İncele - MakaleYalnız künye2010Scopus SJRQ3Investigation of Some Antioxidant Enzymes Activities Depending on Adrenomedullin Treatment and Cold Stress in Rat Liver Tissue
Yildirim, Nuran Cikcikoglu; Yürekli, Muhittin; Yildirim, Numan
Purpose: The aim of this study is to investigate the compensating effects of adrenomedullin on liver tissue after cold stress treatment. Materials and Methods: Male Wistar rats were divided into four groups as control, adrenomedullin, cold stress and cold stress + adrenomedullin treated. Adrenomedullin was given by intraperitoneal injection (2 mg/g body weight) once a day for a week. For cold stress the rats were kept at 10 C for a week. Catalase, glutathione peroxidase and superoxide dismutase activities were measured in liver tissue. Results: Catalase activity was decreased significantly as compared to control in adrenomedullin treated group (p<0.05). There was no significant difference in superoxide dismutase activity (p>0.05). Glutathione peroxidase activity was increased in adrenomedullin treated group but this was statistically insignificant (p>0.05). All enzyme activities were decreased by cold stress (p<0.05). In Adrenomedullin+cold stress group, only the glutathione peroxidase activity was significantly decreased (p<0.05). Conclusion: It is concluded that cold stress induces decrease in catalase, superoxide dismutase and glutathione peroxidase activities in rat liver. Adrenomedullin treatment corrected only glutathione peroxidase activity while decreasing catalase and superoxide dismutase activities further. The discrepancy may be explained by different responses of antioxidant systems to oxidative stress. It can be concluded that oxidative factors may display unexpected effects on the regulation of glutathione peroxidase activities in the adrenonmedullin case.
AtıfWoS8İncele