Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleAçık Erişim2022Scopus SJRQ2
    Age- and Sex-Specific Bioaccumulation of Selected Metals in Freshwater Mussel (Unio elangatulus eucirrus Bourguignat, 1860) Populating from Keban Dam Lake (Elazig, Turkey)

    Danabaş, Durali; Kutluyer, Filiz; Ural, Mesut; Özçelik, Mehtap; Kocabaş, Mehmet

    In aquatic life, environmental chemicals are accumulated by mussels due to their sentinel nature and filter-feeding characteristics. Herein, the present study focused on assessing the concentrations of Cu, Zn, Mg, Mn, Fe, Cd, Pb, Ca, K, and Na levels in freshwater mussels (Unio elangatulus eucirrus) depending on sex and age. For all trace metals, some important differences of bioaccumulations were determined depending on ages and sex. In details, the results indicated that an important age-related accumulation of Mg, Cd, Ca, and K was in females and all trace elements, except Cu, Mg, and K levels in males (p < 0.05). No statistical differences were determined in mean concentrations of Cu, Zn, Mg, and Na. There are statistical differences in Mg, Mn, Fe, and Ca levels between females and males in four aged mussels (p < 0.05). Lead levels were under detectable limits. Overall, metal levels and their toxicity in freshwater mussels should be closely monitored for health of the environment, animals, and humans, since mussels and fish species fed on them are consumed highly in the research region and around.

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 14 · Sudaki Yaşam
    AtıfScopus5WoS6OpenAlex7
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  • MakaleAçık Erişim2022Scopus SJRQ1
    Relationship between the symptoms of COPD and the quality of sexual life

    Kaplan Serin, Emine; Alp Dal, Nursel; Gümüşsoy, Süreyya

    Objective: This study was conducted to assess the relationship between the symptoms experienced by women with COPD and the quality of their sexual life. Method: This study was designed as a descriptive cross-sectional study. The study was conducted at a hospital’s chest diseases clinic located in the western of Turkey. The sample comprises 62 female patients hospitalized with diagnosis of COPD. A questionnaire form, the Medical Research Council Scale (MRCS), the COPD Assessment Test (CAT) and the Sexual Quality of Life-Female (SQOL-F) applied to the women with COPD. Frequency, percentage, mean, standard deviation, Kruskal Wallis test, Mann-Whitney U Test, correlation and regression analysis, were used for the data analysis process. Findings: The decrease in the education level of the participants who have any accompanying chronic disease, and experience symptoms during sexual intercourse negatively affects their quality of sexual life. The quality of sexual life decreases as age, duration of marriage and duration of illness increase (p < 0.05). The results of the linear regression analysis carried out to predict the quality of sexual life of women with COPD shown that the increase in mMRC and CAT significantly decreased the quality of sexual life. These variables explain 58% of the variance. Conclusions: The result of the study shown the sexual quality of life of women with COPD was impaired and COPD symptoms affect them.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus7WoS6OpenAlex11
    ScopusWeb of SciencePubMedİncele
  • DüzeltmeAçık Erişim2022Scopus SJRQ2
    Correction to: Boron-Doped Hydroxyapatite Coatings on NiTi Alloys Using the Electrophoretic Deposition Method: Enhanced Corrosion and Adhesion Performances (Journal of Materials Engineering and Performance, (2021), 30, 10, (7365-7375), 10.1007/s11665-021-05968-x)

    Aksoy, M.E.; Aksakal, B.; Aslan, N.; Dikici, B.

    The following acknowledgment was inadvertently omitted from the originally published article: This work was supported by Yildiz Technical University, C¸ AP (Grant No. FCD-2019-3511).

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  • MakaleYalnız künye2022Scopus SJRQ2
    Effect of nonlinear modeling approaches used for composite elements on seismic behavior of composite framed buildings

    Etlİ, Serkan; Güneyİsİ, Esra Mete

    This study aims to assess the effect of nonlinear modeling approaches used for frame elements while appraising the seismic performance of the composite moment resisting frame (CMRF) buildings. To this, the accuracy and efficiency of two representative numerical models (namely, inelastic force-based frame element-distributed plasticity (DP) and inelastic force-based frame element-plastic hinge length (PHL) (lumped-plasticity)) for the columns and beams of CMRFs are evaluated comparatively. The number of stories of the buildings of the case study ranges from 5 to 15 and consists of columns made of concrete-filled steel tube sections and CMRFs designed with composite beams consisting of a combination of solid reinforced concrete slabs and steel beams. The structures are designed by considering high ductility level. Seismostruct software is used for design and performance analysis. During the performance evaluation of the structures, the nonlinear static pushover analysis is utilized as well as the incremental dynamic analysis. While performing the nonlinear static pushover analysis, the lateral loadings with uniform and triangular load distributions are used, and moreover, a series of earthquake ground motions are used in the incremental dynamic analysis. To evaluate the effect of the modeling approaches, the seismic response of the structures is assessed by comparing the load-displacement response, energy consumption, performance limit. Additionally, the behavior factor, dynamic behavior factor, inherent strength and overstrength factors, ductility factor and global yield value are discussed.

    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
    • SDG 11 · Sürdürülebilir Şehirler ve Topluluklar
    AtıfScopus2WoS2OpenAlex16
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  • MakaleYalnız künye2022Scopus SJRQ2
    Green Synthesis (Paeonia kesrouanensis) of Silver Nanoparticles and Toxicity Studies in Artemia salina

    Unal, İlkay; Egri, Sinan; Ates, Mehmet

    This study aims to describe a simple and environmentally friendly procedure for producing silver nanoparticles (AgNPs) using Paeonia kesrouanensis (P. kesrouanensis) extracts and to determine the toxic effect in the aquatic environment. The morphologies, size, size distributions, and structural properties were analyzed using SEM-EDX, TEM, DLS, zeta potential, FTIR, and XRD. AgNPs were applied to Artemia salina (A.salina), aquatic organism individuals at 7 different concentrations (0.0, 0.2, 1, 5, 10, 25, 50 mg/L) for 24, 48, and 72 h. AgNPs accumulation and elimination, ion release amounts, and the survival rates of organisms were determined at periods of 24, 48, and 72nd hours. The highest accumulation was observed at the 24th hour at the 50 mg/L exposure level. The survival rate decreased as exposure time increased at all concentrations.

    • SDG 6 · Temiz Su ve Sanitasyon
    AtıfScopus6WoS5OpenAlex6
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  • MakaleAçık Erişim2022Scopus SJRQ1
    Chitosan-graft-poly(N‑tert‑butylacrylamide) Copolymer: Synthesis, Characterization and Optimization of Tetracycline Removal Using RSM

    Tanyol, Mehtap; Torğut, Gülben

    In the present study, a graft copolymer was synthesized in accordance with the free radical method using N-tertiary butylacrylamide monomer on chitosan, which is an environmentally friendly polymer. The chemical structure and surface morphology of the newly synthesized graft copolymer were determined by Fourier transform infrared spectroscopy, scanning electron microscopy and X-ray diffraction. Moreover, the thermal behavior was analyzed by thermogravimetric analysis. The chitosan-graft-poly(N‑tert‑butylacrylamide) graft copolymer was used as an adsorbent for the rapid removal of tetracycline from aqueous solutions in order to investigate its applicability. Response surface methodology (RSM) was employed for the optimization of the study conditions, namely adsorbent dosage (0.01–0.04 g 100 mL−1), reaction time (10–90 min) and initial tetracycline concentration (10–100 mg 100 mL−1). The effects of these conditions on tetracycline uptake capacity were examined and the results were statistically analyzed. The RSM results showed that the maximum tetracycline uptake capacity of 104.81 mg g−1 was achieved under the following conditions: adsorbent dose of 0.03 mg 100 mL−1, reaction time of 51.12 min and initial tetracycline concentration of 97.99 mg L−1. ANOVA based on central composite design combined with RSM showed a good agreement between the experimental values and quadratic model estimates, thus resulting in a coefficient (R2) of 0.9118 for tetracycline uptake. The kinetics, isotherms, and thermodynamics of adsorption were examined, and results showed that equilibrium data fitted the Freundlich isotherm model, and the adsorption kinetics of tetracycline followed pseudo-second-order model. Thermodynamic parameters like the enthalpy − 10.39 kJ mol−1 (ΔH°), entropy 0.044 kJ mol−1 K−1 (ΔS°) and Gibbs free energy − 23.26 kJ mol−1 (ΔG°) were evaluated and also, ΔG° shows a negative values indicating that the adsorption process was exothermic and spontaneous. The findings demonstrated that the chitosan-graft-poly(N‑tert‑butylacrylamide) copolymer is an effective adsorbent for pharmaceutical wastewater treatment.

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus11WoS12OpenAlex11
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  • MakaleYayıncıda açık erişim2022Scopus SJRQ2
    Dental Material Detection based on Faster Regional Convolutional Neural Networks and Shape Features

    Imak, Andaç; Çelebi, Adalet; Türkoğlu, Muammer; Şengür, Abdulkadir

    In this paper, a novel approach is proposed to detect the dental materials in dental Panoramic images. In general, dental Panoramic images are examined by the dentists to detect the dental materials of the patients. Examining the dental Panoramic images is a time-consuming procedure and necessitates highly skilled dentists. Thus, computer imaging and decision support systems based on machine learning are in demand for dental applications. In this study, a semi-automatic, image processing and machine learning based approach is proposed for detection of dental materials in dental Panoramic images. More specifically, the dental materials namely dental filling, dental bridge and tooth crown are targeted by the proposed approach. Within the approach developed, the dental Panoramic images used as input are initially pre-processed for noise removal and tooth region is determined using a deep learning approach. To this end, a faster Regional Convolutional Neural Networks (RCNN) method is employed. A tooth region correction procedure is applied after application of faster RCNN to determine the exact location of the tooth region as faster RCNN may produce more tooth regions than one correct tooth region. Graph cut (GC) based image segmentation is applied to segment the tooth region into foreground and background regions. Shape based feature extraction and classification are applied to determine the tooth problem. A dataset has been established in dental faculty hospital of private dental clinics. The proposed approach is simple yet quite effective. In all classification methods, the average accuracy scores were around 90%.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus9WoS7OpenAlex10
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  • MakaleAçık Erişim2022Scopus SJRQ2
    Investigation of the Effects of Deformation Aging Applied to AA 7075 Aluminum Alloy on Mechanical and Metallographic Properties

    Taşgın, Yahya; Ergin, Ramazan

    Aging is quite important in improving the mechanical properties of aluminum alloys. One of the most widely used Al alloys is AA7075 aluminum alloy. Since AA7075 aluminum alloys contain aluminum-zinc-magnesium-copper, various aging processes have been applied to improve their mechanical qualities, and as a result, they have become commercially available. When this aluminum alloy series with increased strength is subjected to any thermal effect in industrial use, the loss of mechanical properties can be reduced by applying deformation aging. In this study, the effect of deformation aging on the mechanical properties of commercially available aluminum alloy has been determined and the relationship between mechanical properties and microstructure examined. Deformation aging was applied to 7075 Al alloy in our study by cooling in air, water and oil at temperatures of 120–180 °C for 2–24 hours. Structural differences were revealed by examining the effects of heat treatment on the mechanical properties and machinability properties of the alloy. As a result of the study, it was observed that metallographic precipitation occurred in the AA7075 Al alloy, and accordingly, intermetallic phases were formed. It is thought that various nanoscale fine precipitates occurring in the matrix of this alloy can also prevent dislocation movements. The study has positive effects on the mechanical properties of the material.

    AtıfScopus9WoS6OpenAlex8
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  • MakaleAçık Erişim2022Scopus SJRQ1
    Cadmium exposure in population: alcoholic beverage consumption and health risk assessment

    Kaplan Ince, Olcay; Ince, Muharrem; Onal, Ali

    Risk assessment of cadmium (Cd) for human health play a key role because of toxic effect. Researchers are undergoing constant development for modelling approaches to make a risk assessment. It was carried out a central composite design combining with response surface modeling to optimize and modeling of Cd2+ ions in this study. Also, this study was performed to provide information about possible risk associated with alcoholic beverage consumption. Some independent process parameters including contact time and pH were chosen for optimization. Under optimal parameters, 142.9 mg g−1 was determined as Cd2+ ions removal effectiveness. Significance independent parameters and their interactions were checked using analysis of variance. These results were verified by correlation coefficients (R2 = 0.9967) of the statistical prediction. Estimated daily intake (EDI) and target hazard quotients (THQ) were calculated, to assess health risk. The Cd2+ ions EDI values (µg/day/person) were less than the recommended dietary allowance values and also, its THQ value was less than 1, also. When the obtained results compared with the levels set by regulatory authorities, the studied alcoholic beverages consumption do not pose a toxicological risk. Graphical abstract: [Figure not available: see fulltext.]

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus3OpenAlex3
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  • MakaleYalnız künye2022Scopus SJRQ2
    Corrosion potential and electromagnetic shielding effectiveness of geopolymer tiles produced with waste metal particles

    Gülmez, Nihan; Koçkal, Niyazi Uğur; Özen, Şükrü; Ateş, Kayhan

    This study is related to the production of special geopolymer specimens, where high effectiveness is provided in terms of electromagnetic interference (EMI) shielding and corrosion resistance. The study is important for the preparation of silica fume/slag based geopolymers by using waste steel and iron powder as a partial substitute for slag aggregate and thus to provide an effective solution to the disposal problems of waste metals. The electromagnetic interference shielding effectiveness (SE) of geopolymer tiles of 7.6 ± 0.1 mm thickness with different metal contents was measured at 4.9–7.05 GHz. Corrosion activity was monitored by measuring the half-cell potential of copper/copper sulphate (Cu/CuSO4) on specimens kept under controlled laboratory conditions for a period of 90 days at %60 relative humidity according to ASTM C876. In addition, anextensive evaluation of the optimization research on the design and proportion of mortar mixtures is presented here. EMI shielding effectiveness of slag based geopolymer tile with 10% steel particles has been determined as 26.1 dB in the frequency range 4.9–7.05 GHz. The results show that the shielding effectiveness reached a maximum of 23.1 decibels (dB) for geopolymer tiles in 40% iron powder content. Also, from experimental results, it was learned that geopolymer specimens with high slag content as binders in the mixtures showed better corrosion resistance.

    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus10WoS10OpenAlex10
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  • MakaleAçık Erişim2022Scopus SJRQ1
    Preparation of ε-Caprolactone/Fe3O4 Magnetic Nanocomposite and Its Application to the Remazol Brilliant Violet 5R Dye Adsorption from Wastewaters by Using RSM

    Pekdemir, Mustafa Ersin; Tanyol, Mehtap; Torğut, Gülben

    In this study, poly (ε-caprolactone)/Fe3O4 magnetic nanocomposite (PCL/Fe3O4 MNC) was synthesized by ring-opening polymerization. Then, PCL/Fe3O4 MNC was used as a novel adsorbent to remove remazol brilliant violet 5R (RBV 5R) from the aqueous media. The effects of PCL/Fe3O4 MNC dosage, process time, and initial RBV 5R concentration on the removal of RBV 5R were studied using the central composite design (CCD) method. The adsorption process was optimized using the response surface methodology, and the optimum conditions were defined. Optimum RBV 5R removal of 95.40% was obtained at a contact time of 167.98 min, PCL/Fe3O4 MNC dosage of 0.40 g, and RBV 5R concentration of 7.18 mg L−1. The process was also designed using the adsorption kinetic models and isotherm. The experimental data of RBV 5R adsorption on PCL/Fe3O4 MNC followed the Langmuir isotherm and pseudo-second-order kinetic models than the other models. Morphological and chemical properties of the adsorbent-adsorbate system indicated the high adsorption yield of RBV 5R on PCL/Fe3O4 MNC was achieved. The structural characteristics of the PCL/Fe3O4 MNC were analyzed by Fourier-transform infrared, attenuated total-reflectance (ATR), and X-ray diffraction. ATR tests showed that no significant change in chemical bond is found in PCL/Fe3O4 MNC before and after the adsorption process. The morphology of composites was investigated by scanning electron microscopy. A vibrating sample magnetometer (VSM) was used for the measurement of the magnetic property. Thermal analysis of MNC was studied using thermogravimetric analysis and differential scanning calorimetry instruments.

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus6WoS5OpenAlex6
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  • MakaleYalnız künye2021Scopus SJRQ2
    Effect of graphene reinforcement on hybrid bioceramic coating deposited on the produced porous Ti64 alloys

    Aslan, N.; Aksakal, B.

    Porous-Ti64 alloys (P-Ti64), produced at various porosities by hot-pressing technique with the help of Mg spacer, were coated by hybrid-Graphene Oxide (rGO) reinforced-hydroxyapatite (HAp), using the sol–gel method. The synthesized rGO powder was used in reinforcing HAp by the Modified Hummers method having 30 µm particle size and nano (nm) scale layer thickness. Hybrid coatings were executed on Ti64 substrates in four different groups as single-HAp, HAp reinforced with 0.5 wt%, 1.0 wt% and 1.5 wt% rGO for three different porosities (41, 52, and 64%) were characterized by FT-IR, Raman, XRD and SEM. The average 21 µm coating film thicknesses were obtained and desirably, the only superficial pores of the substrates were closed by coating material rather than the inner connected open pores. It was also shown that 0.5 wt% and 1.0 wt% rGO reinforcements into HAp prevented crack formation on the Ti64 surfaces, whereas 1.5 wt% rGo reinforcement and single-HAp coatings caused. The highest adhesion strength values were achieved at low porosities (41–52%) and of 0.5–1.0 wt% rGO reinforcements through the adhesion tests.

    AtıfScopus14WoS12OpenAlex20
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  • MakaleAçık Erişim2021Scopus SJRQ1
    Attitudes of Married Muslim Women Regarding Family Planning Methods During the COVID-19 Pandemic in Western Turkey

    Dal, Nursel Alp; Beydağ, Kerime Derya

    COVID-19 had negative effects upon family planning. Women cannot visit healthcare facilities because of a fear of curfew-related sanctions or exposure to COVID-19. It is seen that religious beliefs are influential especially in terms of family planning method preference and having abortions. This study was conducted to determine the attitudes of married Muslim women regarding family planning methods during the COVID-19 pandemic period. The descriptive and cross-sectional study was conducted with 611 married Muslim women who presented to the family planning outpatient clinic of a public hospital in Western Turkey between 1 September 2020 and 1 March 2021. The mean Family Planning Attitude Scale score of the women was found to be 137.53 ± 27.11. It was observed that, as the mean age of the women increased, their family planning attitudes were more positive, and as their number of pregnancies, abortions and living children increased, their attitudes were more negative (p < 0.05). Women do not want to get pregnant during the pandemic process. This is because the effects of COVID-19 on both themselves and the baby to be born are not known, which worries women. Therefore, in order to transform positive attitudes regarding family planning into behavior, it is recommended to provide effective training and consultancy services during the pandemic period.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus5WoS4OpenAlex11
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  • MakaleAçık Erişim2021Scopus SJRQ3
    New exact solutions for the doubly dispersive equation using the improved Bernoulli sub-equation function method

    Dusunceli, Faruk; Celik, Ercan; Askin, Muzaffer; Bulut, Hasan

    In this study, the doubly dispersive equation is presented by the application of the improved Bernoulli sub-equation function method (IBSEFM). The doubly dispersive equation which is a nonlinear partial differential equation is transformed into nonlinear ordinary differential equation using a wave transformation and then is solved by IBSEFM. Some new solutions are successfully constructed. All the obtained solutions in this study have been satisfied the doubly dispersive equation. In the present study, we have used Wolfram Mathematica 9 software for all of the computations and graphic plottings.

    AtıfScopus41OpenAlex48
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  • MakaleAçık Erişim2021Scopus SJRQ1
    Teachers' views related the middle school curriculum for distance education during the COVID-19 pandemic

    Aslan, Seda Akti; Turgut, Yigit Emrah; Aslan, Alper

    This qualitative study aims to examine teachers’ opinions concerning the middle school curricula that have been in use for years, in order to determine its suitability for distance education during the COVID-19 pandemic. The participants consisted of eighteen middle school teachers from different subject areas in Turkey. A maximum variation sampling method was employed for participant selection. The data was collected through semi-structured interviews. Due to the pandemic, the interviews were conducted using video conferencing applications. The data was analyzed through content analysis. According to the findings, the teachers report that while they are effective in achieving cognitive objectives, they have difficulties in achieving affective and psychomotor objectives. In addition, the teachers do not prefer to design their own materials, rather they mainly benefit from ready-to-use materials during emergency distance education. The teachers also reveal that direct instruction and questioning were the teaching methods and techniques they preferred in online courses and that they were unable to adapt other methods and techniques to distance education, which resulted in students experiencing teacher-centered activities. Moreover, the teachers complain about students not attending the online courses on time or even at all, their disinterest, a lack of instant feedback, limited communication with students, and insufficient course lengths. Another critical finding was that the teachers only use homework, end-of-unit quizzes, and participation to online courses as measurement and evaluation tools and agree that they are unable to administer reliable and valid evaluation tools. The limitations of the study and implications for future research are later discussed.

    • SDG 4 · Nitelikli Eğitim
    AtıfScopus18WoS16OpenAlex40
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  • MakaleAçık Erişim2021Scopus SJRQ2
    Fabrication of porous-Ti6Al4V alloy by using hot pressing technique and Mg space holder for hard-tissue biomedical applications

    Aslan, N.; Aksakal, B.; Findik, F.

    Porous-Ti6Al4V (P-Ti6Al4V) alloys were produced using the hot pressing and spacer methods for hard tissue biomedical applications and in particular, the effects of porosity on the mechanical and morphological properties of the structures were investigated. P-Ti6Al4V structures having the homogeneously distributed porosities at 41.08, 52.37 and 64.10% were fabricated by adding 40, 50 and 60% spherical magnesium (Mg) powder with 350 μm particle sizes in average as spacers and evaporating magnesium via the atmosphere-controlled sintering. The obtained porous structures were characterized by SEM, XRD and EDS. Furthermore, the strength and elastic modulus were evaluated by performing compression tests. Elastic modulus and densities were found to be 40–171 MPa, 2–5 GPa and 1.59–2.61, respectively and these values have been shown to decrease with an increase in porosity. The achieved density and mechanical property values, in particular, elastic modulus are close to human bone and within acceptable ranges for with biomedical application purposes. In addition, it was also found out from the analysis of produced P-Ti6Al4V that macropores were responsible for mechanical anisotropy contributed to formation of homogeneous and inter-connected open pores. [Figure not available: see fulltext.]

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus40WoS37OpenAlex39
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  • MakaleYalnız künye2021Scopus SJRQ2
    Characterization of Various Carbon-Based Polypropylene Nanocomposites

    Kaya, Ozge; Buran, Dincer; Akkurt, Nevzat; Yapici, Kerim; Sarac, Mehmet Fahri

    Pure and three types of carbon additives including graphite, graphene, and multi-walled carbon nanotube added into polypropylene (PP) composites as a vibration damping component and sound insulator material in the automotive sector were investigated by using vibrational damping, dynamic mechanical analysis (DMA), tensile, hardness and acoustic behavior tests. According to the obtained results, porosity and distribution of carbon in the polymer matrix are key parameters on the composite parameters causing its reduction of tensile strength and its brittle behavior. Moreover, it seems that 0.01 wt.% graphene and 1 wt.% graphite added PP composites show the highest impact damping properties and also increase the storage and loss modulus of the composite while decreasing the glass transition temperature. The loss factor obtained from DMA and vibration damping test indicated the damping capacity in the interphase of carbon added PP composites depends only on the load applied and not sensitivity upon the natural frequency of the composite system. Depending on the morphological differentiation, graphene added PP composites decrease the sound transmission loss while the 0.1 wt.% MWCNT added PP composites increase sound transmission loss which makes it an alternative vibration damping component.

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  • MakaleAçık Erişim2021Scopus SJRQ2
    Protective Effect of Lutein/Zeaxanthin Isomers in Traumatic Brain Injury in Mice

    Gunal, Mehmet Yalcin; Sakul, Ayse Arzu; Caglayan, Ahmet Burak; Erten, Fusun; Kursun, Oznur Ece Durmaz; Kilic, Ertugrul; Sahin, Kazim

    Previous studies revealed that oxidative stress and inflammation are the main contributors to secondary injury after traumatic brain injury (TBI). In an earlier study, we reported that lutein/zeaxanthin isomers (L/Zi) exert antioxidative and anti-inflammatory effects by activating the nuclear factor-kappa B (NF-κB) and nuclear factor-erythroid 2-related factor 2 (Nrf2) pathways. However, its precise role and underlying mechanisms were largely unknown after TBI. This study was conducted to investigate the potential mechanism of L/Zi isomers in a TBI model induced by a cold injury model in mice. To investigate the effects of L/Zi, male C57BL/6j mice-induced brain injury using the cold trauma model was allocated into two groups (n = 7): (i) TBI + vehicle group and (ii) TBI + L/Zi group (20 mg/kg BW). Brain samples were collected 24 h later for analyses. L/Zi given immediately after the injury decreased infarct volume and blood–brain barrier (BBB) permeability; L/Zi treatment also significantly reduced proinflammatory cytokines, including interleukin1 beta (IL-1β), interleukin 6 (IL-6), and NF-κB levels and increased growth-associated protein 43 (GAP-43), neural cell adhesion molecule (NCAM), brain-derived neurotrophic factor (BDNF), and Nrf2 levels compared with vehicle control. These data suggest that L/Zi improves mitochondrial function in TBI models, possibly decreasing inflammation and activating the Nrf2 pathway.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus39OpenAlex40
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  • MakaleYalnız künye2021Scopus SJRQ2
    Structural, photovoltaic and optoelectronic properties of graphene–amorphous carbon nanocomposite

    Aslan, Naim

    Reduced graphene oxide–amorphous carbon nanocomposites were coated on p-Si wafers to prepare graphene-based photodiodes or photodetectors. Electrophoretic deposition was used to prepare electronic devices. Scanning electron microscopy, energy-dispersive spectra, X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy were used in the morphological and structural characterization. Characterization methods confirm that deposited films are in reduced graphene oxide–amorphous carbon nanocomposite structure. Photoresponsive characteristics were checked using I–V, I–t and C–t techniques. It was seen that diodes are responsive to illumination where increased photocurrent and photocapacitance were obtained for increased illumination intensity. Electrical properties were assessed; C–V, G–V properties were found to depend on AC signal frequency. Signal frequency-dependent behavior was attributed to interface states. The density of interface states was calculated, and it was seen that the density of interface states increases with increasing AC signal frequency. It was illustrated that electrical characteristics of photodiodes were affected by signal frequency and the density of interface states.

    AtıfScopus15WoS15OpenAlex18
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  • MakaleYalnız künye2021Scopus SJRQ2
    Investigation of Microstructural and Mechanical Properties of Different Titanium Alloys for Gamma Radiation Properties and Implant Applications

    Taşgın, Yahya

    In this study, the advantages and disadvantages of different titanium alloys used as industrial and biomedical implant materials are evaluated within the scope of multiple parameters. This research is supported by simulations and aims to understand how titanium and titanium alloys differ mechanically, micro-structurally and in terms of radioactivity. The matrix material of the eight samples used in this research is titanium. The effects of different elements such as Al, V, Sn, Ni, Pb, Mo, Cr, Zr, Fe, Nb, Co on titanium have been examined, the results are compared by considering multiple parameters, and the superior properties of the prominent alloys are highlighted. As a result of the mechanical and electrical tests performed on the alloys, it is obvious that the titanium alloy consisting of Mo and Nb has the highest Brinell hardness, elastic modulus, tensile strength and electrical conductivity parameters compared to other alloys examined within the scope of this research. In the metallographic studies and analyses on samples made up of different alloys, different structures and images emerge for each alloy. These elements rapidly lower the solidification temperature of the material, allowing the β phase to be formed. It has been observed that the two-phase situation has positive effects on the material. On the other hand, the results of gamma ray attenuation tests reveal that Mo and Nb, which make up the alloy, have superior performance compared to other alloy samples due to their high atomic number. Graphical abstract: [Figure not available: see fulltext.]

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