Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Gul, Muhammet(27)
- Celik, Erkan(14)
- Mete, Suleyman(10)
- Serin, Faruk(10)
- Yucesan, Melih(10)
- Serdar, Osman(9)
- Mahomoodally, Mohamad Fawzi(7)
- Zengin, Gokhan(7)
- Aslan, Alper(6)
- Onat, Onur(6)
- Topal, Murat(6)
- Yildirim, Numan(6)
- Ak, Gunes(5)
- Akkurt, Nevzat(5)
- Alataş, Mevlüt(5)
- Batan, Nevzat(5)
- Cevik, Mutlu(5)
- Erten, Fusun(5)
- Icier, Filiz(5)
- Yildirim, Nuran Cikcikoglu(5)
- Yön, Burak(5)
- Aksakal, B.(4)
- Angeloni, Simone(4)
- Aslan, N.(4)
- Cakilcioglu, Ugur(4)
- Caprioli, Giovanni(4)
- Erata, Hüseyin(4)
- Etli, Serkan(4)
- Gürler, Nedim(4)
- Ince, Muharrem(4)
- Işık, Erdem(4)
- Kaplan Serin, Emine(4)
- Kizilkoca, Mustafa(4)
- Kutlu, Banu(4)
- Maggi, Filippo(4)
- Orhan, Cemal(4)
- Paksoy, Mehmet Yavuz(4)
- Pıhtılı, Güzin(4)
- Sahin, Kazim(4)
- Sançar, Taylan(4)
Yayınlar
- MakaleYalnız künye2021Scopus SJRQ4Balneotherapy Features of Natural Thermal Source from Pertek (Turkey-Tunceli) Due to Its Some Chemical, Radioactivity and Biological Parameters
Sönmez, Pinar Erecevit
It can also be defined as a discipline that reviews the factors of balneology or hydrotherapy, which are alternative treatment methods for public health, from chemical, biological and medical aspects. In this study, it was aimed to investigate whether the underground waters in the Pertek district of Tunceli province are suitable for balneology. Chemical, radioactivity analysis, microbiological quality, antimicrobial activities were determined in relation to natural groundwater and its ability to be a natural healing source was investigated. When the chemical content is examined, it was determined to be bromide amount is 0.24 mg / L, Iodine (I); 1.9 mg / L, sulfur (S); 0.02 mg / L, boron (B): 2676 µg / L, silicium (Si); 1.9 mg / L. With respect to the results, thermal water has the feature to be used in balneolotherapy. According to the results of the radioactivity analysis, alpha (α) is 0.15 Bq / L; Beta (β) is <0.30 Bq / L and radon (Rn) is <13.4 Bq / L tritium (T) content is <10 Bq / L (<83.33 TB) and it is included in both mineral and young water group. This ground water and they comply with the standards in terms of microbiology (Total bacteria, coliform, Escherichia coli). Its antibacterial, antifungal and antidermatophyte properties prove to be a healing source. We confirmed the effectiveness of this healing water to both protect and promote human health as a drinking cure and reach the newest and most effective treatment modalities by using related water in Health and Thermal Tourism.
- MakaleYayıncıda açık erişim2021Scopus SJRQ4Effects of magnesium biotinate supplementation on serum insulin, glucose and lipid parameters along with liver protein levels of lipid metabolism in rats
Sahin, Kazim; Orhan, Cemal; Kucuk, Osman; Erten, Fusun; Tuzcu, Mehmet; Sahin, Nurhan; Ojalvo, Sara Perez; Komorowski, James Richard
The objective of this study was to investigate the effects of a novel form of biotin (magnesium biotinate) on serum glucose, lipid profile, and hepatic lipid metabolism-related protein levels in rats. Forty-two rats were divided into six groups and fed a standard diet-based egg white powdered diet supplemented with either d-biotin at 0.01, 1, or 100 mg/kg BW or magnesium biotinate at 0.01, 1, or 100 mg/kg BW for 35 days. Neither form of biotin influenced (p > 0.05) serum glucose or insulin concentrations. Serum total cholesterol and triglyceride decreased with biotin from both sources (p < 0.05). Concentrations were lower with magnesium biotinate when comparing the 1 mg/kg dose (p < 0.05). Serum, liver, and brain biotin and liver cyclic guanosine monophosphate (cGMP) concentrations were greater when rats were treated with magnesium biotinate versus d-biotin, particularly when comparing the 1 and 100 mg/kg dose groups (p < 0.05). Both biotin forms decreased the liver SREBP-1c and FAS and increased AMPK-a1, ACC-1, ACC-2, PCC, and MCC levels (p < 0.05). The magnitudes of responses were more emphasized with magnesium biotinate. Magnesium biotinate, compared with a commercial d-biotin, is more effective in reducing serum lipid concentrations and regulating protein levels of lipid metabolism-related biomarkers.
AtıfScopus5WoS5OpenAlex5
İncele - MakaleAçık Erişim2021Scopus SJRQ2The effect of nurses' compassion on burnout: A cross-sectional study
Kaplan Serin, Emine; Özdemir, Ahmet; Işik, Kevser
Purpose: This study was carried out to determine the effect of nurses' compassion on burnout. Design and Methods: This cross-sectional descriptive study was conducted with 177 nurses. An introductory information form, the compassion scale and the Maslach burnout inventory were used as the data collection tools. Frequency, percentage, t test, analysis of variance, Kruskal-Wallis, correlation, and regression were used in the analysis of the data. Findings: The majority of the participants were determined to be female, married and university graduates. It was determined that there was a significant negative relationship between the nurses' sense of compassion and burnout levels, and burnout decreased as compassion increased. Practical Implication: Burnout and compassion fatigue may lead to inadequate care for the patient. This situation will negatively influence nurses' care quality.
AtıfScopus13WoS10OpenAlex14İncele - MakaleYalnız künye2021Scopus SJRQ2Infrared drying of dill leaves: Drying characteristics, temperature distributions, performance analyses and colour changes
Tezcan, Derya; Sabancı, Serdal; Cevik, Mutlu; Cokgezme, Omer Faruk; Icier, Filiz
Thin-layer drying behaviour of dill leaves samples under three different infrared radiation power intensities was investigated. Diffusion Approach was found to be the best model that describes the drying behaviour of dill leaves. Effective diffusivity values were 6.97 × 10−9, 6.84 × 10−9 and 8.96 × 10−9 m2/s for power intensities of 1790, 1970 and 2070 W/m2, respectively. According to the first and second law efficiencies, the infrared drying system was more efficient at higher power intensities (p < 0.05). However, the total colour change was maximum at the highest power intensity. For the investigated infrared drying conditions, 1970 W/m2 was recommended as the best-infrared power intensity applied for drying of dill leaves by taking into account both performance analyses and quality changes.
AtıfScopus40WoS34OpenAlex44İncele - MakaleYalnız künye2021Scopus SJRQ1İkinci Katil [The Second Murderer]: A Turkish Adaptation of Shakespeare's Scottish Play, Macbeth
Öğütcü, Murat
Serhat Yiğit’s İkinci Katil (2017) is a Turkish adaptation of Shakespeare’s Macbeth. Reminiscent of Tom Stoppard’s Rosencrantz and Guildenstern are Dead (1966), it focuses on minor characters and their otherwise disregarded and peripheral microcosms. However, different from the post-modern self-reflexivity of Stoppard’s play, Yiğit uses an Aristotelian model in his play. Through its concentration on hitherto insignificant minor characters, non-self-reflexive intertextuality, and non-Brechtian acting, İkinci Katil departs both from conventional Shakespearean tragedies and conventionalised avant-garde post-Shakespearean interpretations of these tragedies. The construction of the stage and scenery allows to construct and to deconstruct the play and the source text’s interplay of textual allusions by setting the story of Macbeth to the periphery and the story of the Second Murderer, Warden, to the centre of the action. Therefore, this article will analyse Yiğit’s İkinci Katil and illustrate how the play borrows, adapts and transforms Shakespeare’s Macbeth.
AtıfScopus2WoS1OpenAlex3İncele - MakaleAçık Erişim2021Scopus SJRQ2The usage of Ohmic heating in milk evaporation and evaluation of electrical conductivity and performance analysis
Ariç Sürme, Seda; Sabancı, Serdal
Ohmic heating is based on the principle of heating by passing an alternating current through the product between two electrodes and is an increasingly current electrical heating technique in food applications. The main purpose of the present study is to evaporate milk (cow's milk) from 7.85 kg-water/kg-dry matter (DM) content to approximately 3 kg-water/kg-DM content under atmospheric conditions in different voltage gradients and to examine the electrical conductivity (EC) value during the evaporation process. Also, performance evaluation was determined and compared with the traditional method. It was determined that the total process time in the Ohmic heating assisted evaporation (OHAE) process was 31–92.5 min, while in the traditional evaporation process, the total process time was 41.10 ± 2.1 min. The EC value was 0.43–1.89, 0.44–1.89, and 0.44–1.92 S/m for 7, 9, and 11 V/cm, respectively. In the OHAE process, it was determined that as the voltage gradient increased, the energy and exergy efficiency increased. The lowest energy and exergy efficiency values were obtained in the traditional method. In general, OHAE can be applied to milk, and it was a highly efficient process. Practical applications: Ohmic heating is one of the current electrical heating techniques studied in many areas by researchers. In this study, the change in electrical conductivity and performance values during the milk evaporation process was examined and compared with the traditional method. The OHAE process was more efficient than the traditional method in terms of both energy and exergy efficiency. It is thought that this evaluation will contribute as a data source for both industry and pilot-scale designs. Besides, it will contribute data to the literature with the exergy analysis that is limited in the Ohmic heating process. As a result, a concentrated milk sample with high yield and approximately 3 kg water/kg DM content was obtained.
AtıfScopus21WoS16OpenAlex20İncele - MakaleAçık Erişim2021Scopus SJRQ2Intercultural awareness, communication, and empathy skills in nurses and midwives working in provinces with mass migration
Gümüşsoy, Süreyya; Dal, Nursel Alp; Beydağ, Kerime Derya; Toker, Eylem
Purpose: The study was to evaluate the intercultural awareness, communication, and empathy skills of midwives and nurses (n = 479). Design and Methods: The descriptive study data were collected using the Communication-Skills-Scale (CSS), the Basic-Empathy-Scale (BES), and the Intercultural-Awareness-Scale (IAS). Findings: The total average scores of the CSS, BES, and IAS were found to be 100.07 ± 13.03, 70.70 ± 13.99, and 83.51 ± 14.24, respectively. There was a statistically significant difference between age, education, position, experience and the BES and IAS; gender, providing care for Syrian patients and the CSS and BES; marital status and the BES (P %3C.05). Practice Implications: Nurses and midwives have important responsibilities in terms of protecting and improving the health of migrant women.
AtıfScopus7WoS6OpenAlex9İncele - MakaleYalnız künye2021Scopus SJRQ1Assessment of Seismic Behavior Factor of Code-Designed Steel–Concrete Composite Buildings
Etli, Serkan; Güneyisi, Esra Mete
In this study, the seismic behavior factor of steel–concrete composite buildings was examined. For this purpose, 5-, 10-, 15- and 20-story composite moment-resisting frame (CMRF) buildings having concrete-filled steel tube columns and composite beams were designed at medium ductility (DCM) and high ductility (DCH) levels as per the regulations of Eurocode 8. Examined DCM structures were designed for a PGA of 0.2 g while DCH structures were designed for a PGA of 0.4 g. SeismoStruct software was utilized in the design and performance assessment of the case study structures. Nonlinear static pushover and incremental dynamic analyses were used. In the pushover analysis, the uniform and triangular load distributions were adopted while 12 earthquake ground motions were employed in the dynamic analysis. The effect of ductility levels and number of stories on the seismic behavior of CMRFs was studied using the results of the nonlinear analysis. To this, the variation in the lateral response, global yielding value, code-based behavior factor and component, and dynamic behavior factor were presented for CMRF structures with DCM and DCH. It was observed that the behavior factor of all CMRFs exhibited well above the design assumptions, especially DCM class CMRFs.
AtıfScopus16WoS11OpenAlex34İncele - MakaleYalnız künye2021Scopus SJRQ2Effect of graphene reinforcement on hybrid bioceramic coating deposited on the produced porous Ti64 alloys
Aslan, N.; Aksakal, B.
Porous-Ti64 alloys (P-Ti64), produced at various porosities by hot-pressing technique with the help of Mg spacer, were coated by hybrid-Graphene Oxide (rGO) reinforced-hydroxyapatite (HAp), using the sol–gel method. The synthesized rGO powder was used in reinforcing HAp by the Modified Hummers method having 30 µm particle size and nano (nm) scale layer thickness. Hybrid coatings were executed on Ti64 substrates in four different groups as single-HAp, HAp reinforced with 0.5 wt%, 1.0 wt% and 1.5 wt% rGO for three different porosities (41, 52, and 64%) were characterized by FT-IR, Raman, XRD and SEM. The average 21 µm coating film thicknesses were obtained and desirably, the only superficial pores of the substrates were closed by coating material rather than the inner connected open pores. It was also shown that 0.5 wt% and 1.0 wt% rGO reinforcements into HAp prevented crack formation on the Ti64 surfaces, whereas 1.5 wt% rGo reinforcement and single-HAp coatings caused. The highest adhesion strength values were achieved at low porosities (41–52%) and of 0.5–1.0 wt% rGO reinforcements through the adhesion tests.
AtıfScopus14WoS12OpenAlex20İncele - MakaleAçık Erişim2021Scopus SJRQ3A BAYESIAN NETWORK-BASED APPROACH FOR FAILURE ANALYSIS IN WEAPON INDUSTRY
Yucesan, Melih; Gul, Muhammet; Guneri, Ali Fuat
Gun and rifle manufacturing contain various failures in the process of CNC machining, material supply, research & development, infrastructure and, operator. Due to these failures, the enterprise is exposed to great economic losses and a decrease in competition in the global market. In addition, failures in production cause events that seriously threaten human health. Failure analysis can increase safety by determining the cause of potential errors and taking measures for identified errors in the life cycle of the products. Therefore, this study employs a Bayesian Network (BN)-based modeling approach for capturing dependency among the basic events and obtaining top event probability. Firstly, a fault tree analysis (FTA) diagram is constructed, since its target is to pinpoint how basic event failures result in a top event (system) failure by an AND/OR logical gate. While, AND logical gate should take place in both cases, it is sufficient to realize one of the states in the OR logical gate. Then, a BN-based on fault tree transformation is applied. A case study in a leading weapon factory that produces various types of guns and rifles in the Black Sea region of Turkey is performed. For the application viewpoint, appropriate control measures can be taken into account to decrease the number of failed products based on the performed failure analysis.
AtıfScopus6WoS5OpenAlex7İncele - MakaleAçık Erişim2021Scopus SJRQ1Attitudes of Married Muslim Women Regarding Family Planning Methods During the COVID-19 Pandemic in Western Turkey
Dal, Nursel Alp; Beydağ, Kerime Derya
COVID-19 had negative effects upon family planning. Women cannot visit healthcare facilities because of a fear of curfew-related sanctions or exposure to COVID-19. It is seen that religious beliefs are influential especially in terms of family planning method preference and having abortions. This study was conducted to determine the attitudes of married Muslim women regarding family planning methods during the COVID-19 pandemic period. The descriptive and cross-sectional study was conducted with 611 married Muslim women who presented to the family planning outpatient clinic of a public hospital in Western Turkey between 1 September 2020 and 1 March 2021. The mean Family Planning Attitude Scale score of the women was found to be 137.53 ± 27.11. It was observed that, as the mean age of the women increased, their family planning attitudes were more positive, and as their number of pregnancies, abortions and living children increased, their attitudes were more negative (p < 0.05). Women do not want to get pregnant during the pandemic process. This is because the effects of COVID-19 on both themselves and the baby to be born are not known, which worries women. Therefore, in order to transform positive attitudes regarding family planning into behavior, it is recommended to provide effective training and consultancy services during the pandemic period.
AtıfScopus5WoS4OpenAlex11İncele - DüzeltmeYalnız künye2021Scopus SJRQ1Corrigendum to “Influence of partial sodium replacement on proximate composition, physical and sensory quality of marinated anchovy (Engraulis encrasicolus)” [LWT 137 (2021) (February 2021) 110476] (LWT (2021) 137, (S002364382031464X), (10.1016/j.lwt.2020.110476))
Erol, Nida Demirtas; Erdem, Ömer Alper; Cakli, Sukran
The authors regret Arzu Burcu Yavuz who is one of the authors of our article requested to withdraw her name from our article titled “Influence of Partial Sodium Replacement on Proximate Composition, Physical and Sensory Quality of Marinated Anchovy (Engraulis encrasicolus).” As the other authors of the article, we agree with this request and have removed Dr. Burcu from this article. The updated authorship is as listed above. The authors would like to apologise for any inconvenience caused.
AtıfScopus1İncele - MakaleYalnız künye2021Scopus SJRQ2High temperature effect on quasi-static and low velocity impact behaviors of advanced composite materials
Karakuzu, Ramazan; Djele, Akim; Dogan, Akar
In this study, the effect of ambient temperatures on the punch shear and low-velocity impact behavior of S2 glass fabric and carbon-kevlar hybrid fabric reinforced epoxy composites was investigated. The quasi-static tests (QST) were performed by using a Universal Shimadzu Tensile Testing Machine with various crosshead speeds. Low-velocity impact (LVI) tests were also carried out by using the CEAST Fractovis Plus impact test machine at different impact energies. Flat-nose impactors with a cylindrical punch diameter of 12.70 mm were mounted to the test machines. Both tests have been carried out at various temperatures. After the experiments, the load-displacement, the absorbed energy-impact energy/crosshead speed and punch shear strength graphs are plotted. From the obtained results it can be said that, in penetration cases of low-velocity impact and quasi-static tests, absorbed energy and punch shear strength values show similar behavior for hybrid carbon-kevlar/epoxy at each temperature except for 80 °C while these values are different from each other for S2 glass/epoxy at all temperatures.
AtıfScopus16WoS14OpenAlex14İncele - MakaleAçık Erişim2021Scopus SJRQ2Towards the circular economy: Analysis of barriers to implementation of Turkey’s zero waste management using the fuzzy DEMATEL method
Ayçin, Ejder; Kayapinar Kaya, Sema
Zero waste has an important position in the circular economy model in terms of manufacturing recyclable products instead of products to be consumed quickly, reducing the amount of waste, developing and implementing recycling/reuse technologies, and thus ensuring resource efficiency. A zero-waste strategy is one of the basic steps to achieve the goal of the circular economy. The number of studies conducted on Turkey’s zero waste management strategies referring to the circular economy is quite limited. To fill this gap in the literature, this study aims to identify the potential barriers which have an important role in zero waste management practices in Turkey. Through a broad literature review and expert opinions, 12 key barriers for zero waste implementation in Turkey have been defined in view of circular economy principles. Then, fuzzy DEMATEL methodology is employed to examine which is the most influential barrier affecting zero waste management success and to identify the interdependence of these barriers. The results indicate that uncertainty of the goals and tactics relevant to the circular economy and lack of financial and economic aid are key causal barriers that affect Turkey’s zero waste management.
AtıfScopus65WoS49OpenAlex85İncele - MakaleYalnız künye2021Scopus SJRQ1Problem- based learning in live online classes: Learning achievement, problem-solving skill, communication skill, and interaction
Aslan, Alper
The purpose of the study is to investigate the effect of first aid training in live online classes using the problem-based learning approach on students' learning achievement, problem-solving skills, communication skill, and interaction. The pre-test and post-test quasi-experimental design with a control group was used in the quantitative dimension of the study. The study group was conducted with forty-five university students. While live online classes in the experimental group were carried out via the PBL approach, live online classes in the control group were traditionally carried out via teacher-based methods without any intervention. Zoom application was used in both groups during live online classes. Group work in the experimental group was conducted using breakout rooms. The process of data collection and the experimental procedure of the study was completed in six weeks. Within the scope of the study, courses took three 40 min periods every week. The Learning Achievement Test, the Perceived Problem-solving Skills Scale, the Communication Skills Scale, and the Online Course Interaction Level Determination Scale were used for data collection tools. The results of study show that students who attended live online classes using PBL had higher levels of learning achievement, problem-solving skills and live online class interaction than students who attended live online classes using teacher-based methods. No significant difference between the communication skills of the groups was observed.
AtıfScopus143WoS76OpenAlex229İncele - MakaleAçık Erişim2021Scopus SJRQ3New exact solutions for the doubly dispersive equation using the improved Bernoulli sub-equation function method
Dusunceli, Faruk; Celik, Ercan; Askin, Muzaffer; Bulut, Hasan
In this study, the doubly dispersive equation is presented by the application of the improved Bernoulli sub-equation function method (IBSEFM). The doubly dispersive equation which is a nonlinear partial differential equation is transformed into nonlinear ordinary differential equation using a wave transformation and then is solved by IBSEFM. Some new solutions are successfully constructed. All the obtained solutions in this study have been satisfied the doubly dispersive equation. In the present study, we have used Wolfram Mathematica 9 software for all of the computations and graphic plottings.
AtıfScopus41OpenAlex48İncele - MakaleYalnız künye2021Scopus SJRQ2Examination of contact problem between functionally graded punch and functionally graded layer resting on elastic plane
Polat, Alper
In this study, continuous contact problem in the functionally graded (FG) layer loaded with a FG flat punch resting on the elastic semi-infinite plane was analyzed by the finite element method (FEM). It was assumed that the shear modulus and density of the layer and punch varied according to exponentially throughout their depth. FG layer's weight was included to the problem and additionally all surfaces were considered as frictionless. Analysis of FG materials was performed with a special macro which was added to the ANSYS program. Firstly, the shear modulus of the punch was considered to be very rigid and the results of initial separation load (λcr) and distance (xcr) were compared with the analytical solution. Afterwards, results obtained from the contact analysis made according to the inhomogeneity parameters (β, γ) between FG punch-FG layer which had been unprecedented in the literature were discussed. As a result, FG punch's stress values at the punch edges where stress accumulations occurred were found to be smaller than the rigid punch. The security of the structure, longer life of the material and ease of production are directly related to the reduction of the stress values. The results obtained in this study are important in this respect. Also this work is the first study that investigates the effect of FG punch on the FG layer.
AtıfScopus8WoS10OpenAlex2İncele - MakaleAçık Erişim2021Scopus SJRQ1Control of switched reluctance generator in wind power system application for variable speeds
Omaç, Zeki; Cevahir, Ceren
Switched reluctance generators (SRGs) come into prominence in other electrical machines with its simple structure, only stator winding, reliability, high fault tolerance and the possibility of working within wide speed range. These generators are used especially in wind power plants due to their ability to operate in variable speed range and applications of aviation and electric cars. In this study, the control of the SRG was performed. A simulation of SRG driver in Matlab/Simulink was performed and the real-time implementation control of SRG is carried out on DS1103 Ace kit digital signal processor to determine the performance of the SRG. The output voltage of the SRG is controlled by the proportional-integral (PI) voltage controller. As a result, the graphs of change in SRG phases currents and SRG output voltage were obtained according to different parameters. Simulation results compared with experimental results. Consequently, they overlap on experimental results.
AtıfScopus25WoS8OpenAlex27İncele - MakaleAçık Erişim2021Scopus SJRQ3The protective effect of chrysin against carbon tetrachloride-induced kidney and liver tissue damage in rats
Baykalir, Burcu Gul; Arslan, Aslihan Sur; Mutlu, Seda Iflazoglu; Parlak Ak, Tuba; Seven, Ismail; Seven, Pinar Tatli; Yaman, Mine; Gul, Huseyin Fatih
The aim of this study was to investigate the possible protective effects of chrysin on oxidative status and histological alterations against carbon tetrachloride (CCl4)-induced liver and kidney tissue in rats. The animals were randomly divided into four groups; the control, chrysin (100 mg/kg), CCl4 (0.5 ml/kg) and chrysin + CCl4 groups. Liver and kidney injuries were assessed by biochemical and histopathological examinations. The levels of malondialdehyde (MDA), reduced glutathione (GSH), and superoxide dismutase (SOD) activity were measured in tissues. Serum tumor necrosis factor-α (TNF-α), aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea, and creatinine levels were also measured in blood samples. MDA, serum TNF-α, AST, ALT, urea, and creatinine levels (p < 0.05) were significantly higher, and SOD activity and GSH level were significantly (p < 0.05) lower in the CCl4 group than in the control group. Treatment with chrysin in the chrysin + CCl4 group decreased MDA, AST, ALT, creatinine, and TNF-α levels (p < 0.05), and increased SOD activity, GSH levels (p < 0.05), and serum TNF-α levels (p < 0.05). In addition, body weight change (BWC) (p < 0.05) and feed intake (FI) were significantly lower (p < 0.001) in the CCl4 group than in the control group. Moreover, treatment with chrysin increased BWC and FI in the chrysin + CCl4 group compared with that in the CCl4 group. These findings also confirmed by histopathological examination. The chrysin treatment ameliorated the CCl4-induced biochemical and pathological alterations. These results demonstrated that chrysin provided amelioration on the rat liver and kidney tissues CCl4-induced injury by increasing the antioxidant activity.
AtıfScopus20İncele - MakaleYalnız künye2021Scopus SJRQ2Cellular responses of spirlin Alburnoides bipunctatus spermatozoa exposed to Bisphenol A: Biochemical response and sperm quality alterations evaluation
Kocabaş, Mehmet; Kutluyer, Filiz; Çakir Sahilli, Yeliz; Aksu, Önder
Plastics are one of the global environmental problems owing to their highest production. Bisphenol A (BPA) is used in the manufacturing of plastics including polycarbonate, polyvinyl chloride and resins. In particular, aquatic ecosystems are adversely affected by the occurrence of micropollutants. In addition, BPA as a typical endocrine-disrupting chemical (EDC) seriously influences androgenic activity and reproduction of aquatic organisms, particularly fish as non-target organism. In toxicological assays, sperm cells can be used as a potential tool for reliable and practical assessment. For these reasons, sperm cells were exposed to lower concentrations (0 µg/L, 0.5 µg/L, 1.25 µg/L, 2.5 µg/L and 5 µg/L) of BPA and the study focused on BPA-induced oxidative stress. The enzymatic [glutathione peroxidase (GSH-Px), catalase (CAT) and superoxide dismutase (SOD)] activities and lipid peroxidation (MDA) were analyzed in spermatozoa. The study findings showed that the activities of SOD and GSH-Px were significantly decreased by BPA but lipid peroxidation (MDA) and CAT acticity increased. Notably, the percentage and duration of motile sperm cells decreased. Collectively, spermatozoa clearly showed the sensitivity even at extremely low concentrations. This is first report to assess the impact of BPA on sperm cells of spirlin Alburnoides bipunctatus.
AtıfScopus6WoS6OpenAlex5İncele