Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Gul, Muhammet(27)
- Celik, Erkan(14)
- Mete, Suleyman(10)
- Serin, Faruk(10)
- Yucesan, Melih(10)
- Serdar, Osman(9)
- Mahomoodally, Mohamad Fawzi(7)
- Zengin, Gokhan(7)
- Aslan, Alper(6)
- Onat, Onur(6)
- Topal, Murat(6)
- Yildirim, Numan(6)
- Ak, Gunes(5)
- Akkurt, Nevzat(5)
- Alataş, Mevlüt(5)
- Batan, Nevzat(5)
- Cevik, Mutlu(5)
- Erten, Fusun(5)
- Icier, Filiz(5)
- Yildirim, Nuran Cikcikoglu(5)
- Yön, Burak(5)
- Aksakal, B.(4)
- Angeloni, Simone(4)
- Aslan, N.(4)
- Cakilcioglu, Ugur(4)
- Caprioli, Giovanni(4)
- Erata, Hüseyin(4)
- Etli, Serkan(4)
- Gürler, Nedim(4)
- Ince, Muharrem(4)
- Işık, Erdem(4)
- Kaplan Serin, Emine(4)
- Kizilkoca, Mustafa(4)
- Kutlu, Banu(4)
- Maggi, Filippo(4)
- Orhan, Cemal(4)
- Paksoy, Mehmet Yavuz(4)
- Pıhtılı, Güzin(4)
- Sahin, Kazim(4)
- Sançar, Taylan(4)
Yayınlar
- MakaleYalnız künye2021Scopus SJRQ2Investigation of Tie Bars Axial Force Demands in Composite Plate Shear Walls—Concrete Filled
Polat, Erkan; Kenarangi, Hadi; Bruneau, Michel
Tie bars axial force demands due to concrete dilation and prying action were investigated through numerical studies. In the first part of this study, the Karagozian and Case Concrete model, which proved to provide reasonable in-plane flexural cyclic inelastic wall response while accounting for concrete dilation effect, was used to investigate the variation of confinement inside the infill concrete, the distribution of passive confining pressures at the steel–concrete interface, and the resulting tie bar axial force demands. Finite element analyses involving C-PSW/CF having different tie spacings, wall depths, and wall thicknesses were performed. In the second part of this study, the influence of plate local buckling on tie bar axial force demand was investigated and explained by prying action. A separate finite element study was performed to investigate the significance of prying action and equations were developed from free-body diagrams. The results showed the significance of the passive confining pressures due to concrete dilation, and prying action due to local plate buckling, on imparting axial forces in tie bars. Neither of these behavior are currently considered as design parameters for tie bars. The numerical analyses and results presented here are intended to provide useful insights and direction for the design and instrumentation of future C-PSW/CF experiments by the broader research community.
AtıfScopus9WoS8OpenAlex8
İncele - Kitap BölümüYalnız künye2021Economic and social impacts of COVID-19 on European tourism
Kazar, Gorkemli; Kazar, Altug; Akpinar, Tuba
European tourism has been largely disrupted by the pandemic throughout 2020. In this study, the economic and social effects of COVID-19 on the tourism sector of European countries were examined. To understand the extent of the pandemic on European tourism, policies followed by countries, physical tourism flows of the accommodation sector, tourism employment, and turnover rates were considered. The study showed that the European tourism sector, especially after the second half of 2020, was hit socially and economically by the devastating effects of the pandemic. In addition, the study revealed the necessity for radical regulations within the sector in the post-pandemic period.
- MakaleYayıncıda açık erişim2021Scopus SJRQ2Investigation of antioxidant properties of chamomile consumed as herbal tea
Karaaslan Ayhan, Nagihan
Common chamomile is consumed as herbal tea due to its antioxidant properties and biological activities in daily life. In this study, antioxidant activities and total phenolic contents of white and yellow chamomiles were investigated in terms of extraction methods and solvent types. In all extraction methods used for extraction of both chamomiles, the best antioxidant activity and total phenolic results were obtained with water extracts. Also, the best yield was found with sonication-assisted stirring for both chamomile extracts obtained using three extraction solvents. DPPH and ABTS radical scavenging activities obtained by sonication-assisted stirring for water extracts were 10.886 ± 0.244 mg TEAC/g and 8.702 ± 0.567 mg TEAC/g for white chamomile, and 11.709 ± 0.693 mg TEAC/g and 11.139 ± 0.514 mg TEAC/g for yellow chamomile. The total phenolic contents were determined as 3.863 ± 0.325 mg GAE/g for white chamomile and 5.225 ± 0.417 mg GAE/g for yellow chamomile. Novelty impact statement: In this study, the antioxidant properties of white and yellow chamomile were examined in detail in terms of different extraction methods and solvent types. Sonication-assisted stirring and water were determined to be the best extraction method and solvent for both chamomiles. According to the results, it can be stated that chamomile has higher antioxidant properties than white chamomile under the best extraction conditions.
AtıfScopus9WoS9OpenAlex8İncele - MakaleAçık Erişim2021Scopus SJRQ4Interpolation Of Surfaces With Asymptotic Curves In Euclidean 3-Space
Altın, Mustafa; Üna, İnan; Mofarreh, Fatemah
In this paper, we investigate the interpolation of surfaces which are obtained from an isoasymptotic curve in 3D-Euclidean space. We prove that there exists a unique C0-Hermite surface interpolation related to an isoasymptotic curve under some special conditions on the marching scale functions. Finally, we present some examples and plot their graphs.
- BildiriAçık Erişim2021Deep Neural Network Trained on Surface ECG Improves Diagnostic Accuracy of Prior Myocardial Infarction over Q Wave Analysis
Yildirim, Ozal; Baloglu, Ulas B; Talo, Muhammed; Ganesan, Prasanth; Tung, Jagteshwar S; Kang, Guson; Tooley, James; Alhusseini, Mahmood I.; Baykaner, Tina; Wang, Paul J.
Clinical screening of myocardial infarction is important for preventative treatment and risk stratification in cardiology practice, however current detection by electrocardiogram Q-wave analysis provides only modest accuracy for assessing prior cardiac events. We set out to evaluate the ability of a deep neural network trained on the electrocardiogram to identify patients with clinical history of myocardial infarction. We assessed 608 patients at two academic centers with adjudicated history of myocardial infarction. Surface electrocardiograms were used to train a neural network-based model that classifies patients with and without a history of infarction. Endpoints were assessed by clinical record review and accuracy of the model was compared against the manual assessment of pathologic Q waves. The neural network outperformed the accuracy of pathologic Q waves (62%). In training, the model accuracy converged to >98%. Validation was performed by cross-validation (k=5) with validation accuracy 71 ± 5%. Receiver-operator characteristics analysis resulted in a c-statistic of 0.730. Deep learning of a 12-lead ECG can identify features of prior myocardial injury more accurately than clinical Q-wave analysis and may serve as a valuable clinical screening tool.
AtıfScopus3OpenAlex3İncele - MakaleAçık Erişim2021Scopus SJRQ2Protective Effect of Lutein/Zeaxanthin Isomers in Traumatic Brain Injury in Mice
Gunal, Mehmet Yalcin; Sakul, Ayse Arzu; Caglayan, Ahmet Burak; Erten, Fusun; Kursun, Oznur Ece Durmaz; Kilic, Ertugrul; Sahin, Kazim
Previous studies revealed that oxidative stress and inflammation are the main contributors to secondary injury after traumatic brain injury (TBI). In an earlier study, we reported that lutein/zeaxanthin isomers (L/Zi) exert antioxidative and anti-inflammatory effects by activating the nuclear factor-kappa B (NF-κB) and nuclear factor-erythroid 2-related factor 2 (Nrf2) pathways. However, its precise role and underlying mechanisms were largely unknown after TBI. This study was conducted to investigate the potential mechanism of L/Zi isomers in a TBI model induced by a cold injury model in mice. To investigate the effects of L/Zi, male C57BL/6j mice-induced brain injury using the cold trauma model was allocated into two groups (n = 7): (i) TBI + vehicle group and (ii) TBI + L/Zi group (20 mg/kg BW). Brain samples were collected 24 h later for analyses. L/Zi given immediately after the injury decreased infarct volume and blood–brain barrier (BBB) permeability; L/Zi treatment also significantly reduced proinflammatory cytokines, including interleukin1 beta (IL-1β), interleukin 6 (IL-6), and NF-κB levels and increased growth-associated protein 43 (GAP-43), neural cell adhesion molecule (NCAM), brain-derived neurotrophic factor (BDNF), and Nrf2 levels compared with vehicle control. These data suggest that L/Zi improves mitochondrial function in TBI models, possibly decreasing inflammation and activating the Nrf2 pathway.
AtıfScopus39OpenAlex40
İncele - MakaleYalnız künye2021Scopus SJRQ2Recovery of Cu(II) by Acorga M5640 After Leaching of Malachite Ore in Perchloric Acid Solutions
Demirkıran, Nizamettin; Tanaydın, Mehmet Kayra
Abstract: In the present study, the recovery of Cu2+ from the resulting actual leach solution after the leaching of malachite ore in perchloric acid solutions was examined by applying the solvent extraction method. The organic phase was prepared using Acorga M5640 and kerosene. The effects of the initial pH of solution, extractant concentration, Cu2+ concentration, temperature, and stirring speed on the extraction process were investigated. It was determined that the extraction yield increased with an increase in the extractant concentration, initial pH of aqueous solution, stirring speed, and temperature, and with a decrease in the concentration of Cu2+. To prevent or minimize Zn2+ transfer to the organic phase and to ensure maximum Cu2+ extraction from the aqueous phase, the optimal values for the initial pH of the aqueous phase, initial concentration of Cu2+, extractant concentration, temperature, and stirring speed were selected to be 1, 0.152 g/L, 4% (v/v), 25 °C, and 400 rpm, respectively. The stoichiometry and mechanism of the extraction process were determined applying the equilibrium slope method. The changes in the Gibbs free energy, enthalpy, and entropy were determined. The changes in these thermodynamic parameters were calculated to be − 3.87 kJ/mol, 64.67 kJ/mol, and 0.23 kJ/(mol K), respectively. Graphical Abstract: The extraction percentage of Cu2+ increases substantially when the initial pH of the leach solution increases from 0.1 to 1. The further increase in the initial pH above 1 does not create an increase in the extraction extent of Cu2+. When the initial pH of the leach solution is higher than 1, the amount of Zn2+ transferred from the aqueous phase to the organic phase increases significantly.[Figure not available: see fulltext.].
AtıfScopus7WoS5OpenAlex9İncele - MakaleYalnız künye2021Scopus SJRQ4Reflection of eating awareness and life engagement of university students on the coronavirus (COVID-19) pandemic
Önen, Cihan; Sandikçi, Muhammed Bahadır
Study Objectives: With the restrictions in the pandemic process and the distance education process, changes have occurred in the diet of students. In such periods, which affect human life in a significant way in terms of public health, nutrition must be managed well. The study was conducted to evaluate the eating awareness of university students during the COVID-19 pandemic period and to examine its relationship with their engagement in life. Methods: The population of the cross-sectional study consists of the students of Munzur University. As a precaution regarding the COVID-19 pandemic, the participants were reached on the internet. Results: Eating awareness was statistically higher in men, married people, those with normal weight, and older students. While the life engagement among university students was high, the mean scores of eating awareness and its sub-components were moderate. Life engagement was significantly higher in sports science students than students in other academic units. There was a weak but significant relationship between eating awareness and engagement in life. Conclusion: Eating awareness of university students during the pandemic is at a moderate level. Students with high eating awareness are attached to life more. The highest life engagement among academic units is among sports science students. There is a need for public health initiatives to increase the awareness of eating among the students, against COVID-19 and possible future pandemics.
AtıfScopus3WoS2OpenAlex3İncele - MakaleYalnız künye2021Scopus SJRQ2Effect of the Mixing Structure Parameters of a Self-reflux Burner on Combustion Characteristics and NOx Emission
Xu, Qian; Shen, Meng; Shi, Kejian; Liu, Zhihui; Akkurt, Nevzat; Xiong, Yaxuan; Liu, Lin; Feng, Junxiao; Wang, Jiulong
To solve the problem of low efficiency of NOx emission reduction in self-reflux burners, this study is based on the concept of coordinated control of self-reflux burner structural and thermal parameters. After completing the structural design and optimization of thermal parameters, we continue to adjust the two key structural parameters: the nozzle axis distance and the length of the cylindrical section, to minimize NOx emissions. These are the two parameters that chiefly affect the mixing of flue gas and fuel gas. The results show that increasing nozzle axis distance can delay the mixing of gas and air and create a more uniform oxygen concentration field for the combustion process. The maximum combustion temperature is reduced from 1973.65 K to 1935.88 K and the volume fraction of NOx in the flue gas is reduced from 188.08×10−6 to 143.47×10−6. However, compared with the nozzle axis distance, the length of the cylindrical section of the burner has little effect on the mixing of the flow field. Under different cylindrical section lengths, the maximum combustion temperature does not change more than 3 K, and the volume fraction of NOx in the flue gas changes within 5×10−6.
AtıfScopus3OpenAlex2İncele - MakaleYalnız künye2021Scopus SJRQ2Chrysin protects against testicular toxicity caused by lead acetate in rats with its antioxidant, anti-inflammatory, and antiapoptotic properties
Ileriturk, Mustafa; Benzer, Fulya; Aksu, Emrah Hicazi; Yildirim, Serkan; Kandemir, Fatih Mehmet; Dogan, Tuba; Dortbudak, Muhammet Bahaeddin; Genc, Aydin
In the present study, the protective effects of chrysin (CHR) against testicular damage caused by lead acetate (PbAc) were examined. In this way, 30 min after rats were given 25 and 50 mg/kg/b.w CHR orally for seven consecutive days, 30 mg/kg/b.w PbAc was administered orally. In biochemical analysis of testicular tissue, it was found that PbAc-reduced antioxidant parameters [glutathione peroxidase (GPx), glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT)], while it increased lipid peroxidation, inflammatory markers [nuclear factor kappa-B (NF-κB), cyclooxygenase-2 (COX-2), prostaglandin E2 (PGE-2), and inducible nitric oxide synthase (iNOS)], and 8-hydroxy-2′-deoxyguanosine (8-OHdG). In the immunohistochemical examination, it was determined that PbAc increased the expression of tumor necrosis factor-α (TNF-α) and caspase-3. Accordingly, PbAc was found to cause a decrease in sperm motility and an increase in the percentage of dead sperm. However, it has been observed that CHR relieves oxidative stress due to its antioxidant properties, thus protecting against inflammation and apoptosis. It also allowed the CHR sperm parameters to return to control group levels. The results revealed that CHR could be a natural substance to be used in Pb-induced testicular toxicity. Practical applications: Lead (Pb) is an important environmental contaminant heavy metal. Pb is believed to reduce fertility in men. Oxidative stress plays a significant role in the damage caused by Pb to testicular tissue. CHR is an antioxidant substance that occurs naturally in various plants and has various pharmacological properties. In the present study, it was investigated whether CHR has a protective effect against testicular toxicity induced by PbAc. The results revealed that in rats, CHR protects the testicular tissue from PbAc toxicity by showing antioxidant, anti-inflammatory and anti-apoptotic effects, thus bringing sperm parameters closer to normal.
AtıfScopus76WoS71OpenAlex81İncele - MakaleYalnız künye2021Scopus SJRQ2Investigation of time effect on pectin production from citrus wastes with ohmic heating assisted extraction process
Sabanci, Serdal; Çevik, Mutlu; Göksu, Ali
Pectin is usually extracted by exposure to a high temperature and a specific pH value by conventional methods. However, due to reasons such as low energy efficiency of the process and damage to the pectin, alternative thermal and non-thermal methods are used in the pectin extraction process. In this study, the effect of different processing times (0, 5, 15, 30, 60, 120, 180 min) on pectin extraction was investigated for grapefruit, lemon, and orange samples at 80°C. Besides, it was determined that the electrical conductivity value ranged between 1.46–2.06 S/m during heating, the electrical conductivity value of the pH solution adjusted with sulfuric acid. Accordingly, it was figured out that the total amount of energy consumed increases as the process holding time increases. However, it was determined that there was a decrease in the average power value by turning on–off the system. Practical Application: Pectin is one of the additives used in many areas in the food industry. Pectin is now produced especially from agricultural waste peel. During this production, it is subjected to long processes at certain pH and certain temperatures. With the present study, determination of pectin yield over a wide period of time by using ohmic heating process and total ohmic heating energy was determined. In this way, it is thought that a serious contribution will be made to the literature and industry regarding different industrial agricultural waste peel (orange, grapefruit, lemon) during pectin production.
AtıfScopus36WoS31OpenAlex36İncele - MakaleYalnız künye2021Scopus SJRQ2Developing Antibacterial Cotton Fabric with Zinc Borate Impregnation Process
İpek, Yeliz; Ertekin, Özlem
Cotton fabric is a commonly used textile because of its natural and healthy properties. The chemical structure of cotton consists cellulose with a ratio of over 90 %. Cellulose is a natural polymer and cotton fabric is a quiet useful textile because of its better moisture absorption, softness, and easy care properties. Moisture absorbtion property comes from the cellulosic structure of the fabric. However, its features such as being hydrophilic and inclinable to bacterial growth limits its application areas. Antibacterial cotton fabric may be used for hospital textiles such as hospital gowns, patient clothes, wound bandages; food packaging and storage textiles; home textiles like curtain, bed cover; clothing, etc. In this study, a novel environmentally friendly antibacterial cotton fabric was developed. Flame retardant zinc borate was used as antibacterial agent. For this purpose, zinc borate with a formula of ZnO·3B2O3·7H2O had been synthesized with wet chemical precipitation method and cotton fabric was treated with this material via sol-gel impregnation method. The impregnation method for cotton fabric provided a uniform distribution of zinc borate particles and processing the entire volume of the fiber. This method is also suitable for large quantity production processes. In the microbiological studies, Enterococcus which is commonly associated with the nosocomial infections and food spoilage was used. As a result, the antibacterial activity was observed in the fabrics treated with 0.1 mol·l−1 and 0.2 mol·l−1 concentration of zinc borate solutions.
AtıfScopus16WoS13OpenAlex14İncele - MakaleYalnız künye2021Scopus SJRQ1Protective Effects of Chrysin Against Oxidative Stress and Inflammation Induced by Lead Acetate in Rat Kidneys: a Biochemical and Histopathological Approach
Kucukler, Sefa; Benzer, Fulya; Yildirim, Serkan; Gur, Cihan; Kandemir, Fatih Mehmet; Bengu, Aydin Sukru; Ayna, Adnan; Caglayan, Cuneyt; Dortbudak, Muhammet Bahaeddin
In this study, the protective effects of chrysin (CR) on lead acetate (PbAc)-induced renal toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and immunohistochemical methods. In the study, rats were given orally at 30 mg/kg/body weight (BW) PbAc after CR of 25 and 50 mg/kg/BW was administered to them orally (a total of 7 administrations for 7 days). The results showed that CR reduced urea and creatinine levels by alleviating PbAc-induced kidney damage. It was determined that CR decreases PbAc-induced lipid peroxidation due to its antioxidant properties and increases catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx) activities, and glutathione (GSH) levels. It was also detected that CR protects DNA from the toxic effects of PbAc and reduces 8-hydroxy-2′-deoxyguanosine (8-OHdG) levels. Biochemical and immunohistochemical findings demonstrated that CR had anti-inflammatory and antiapoptotic effects and reduced nuclear factor kappa-B (NF-κB), interleukin-33 (IL-33), prostaglandin-E2 (PGE-2), tumor necrosis factor-α (TNF-α), p53 levels, and the activities of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), which were increased with PbAc administration. Moreover, CR was found to increase the levels of aquaporin-1 (AQP-1) and nephrine in PbAc-induced kidney tissue. CR decreased the contents of lead (Pb), zinc (Zn), iron (Fe), sodium (Na), and copper (Cu) and increased those of potassium (K) calcium (Ca) in renal tissue. These results indicated that CR considerably alleviates kidney toxicity caused by PbAc.
AtıfScopus136WoS118OpenAlex145İncele - MakaleAçık Erişim2021Scopus SJRQ1Thermoset powder coating wastes as filler in LDPE – Characterization of mechanical, thermal and morphological properties
Kismet, Yilmaz; Dogan, Akar; Wagner, Manfred H.
In this study, three different electrostatic powder coating wastes of thermoset structure were used as fillers for low-density polyethylene (LDPE). The mechanical, thermal, and morphological properties of these composites materials are reported. The thermoset powder coating wastes were hydrolyzed using water and alcohol, and then 10%, 20%, and 30% by weight of the deactivated wastes were mixed with LDPE, first in a mechanical dry mixer, and subsequently homogenized by melt compounding in an extruder at about 160 °C. Standard tensile test bars and plate-shaped samples were produced from these homogeneous compounds by injection molding. The effects of adding hydrolyzed powder coating wastes on the properties of LDPE were determined by mechanical, thermal, and morphological tests. Tensile strength and perforation threshold of the sample filled with powder coating wastes decreased to some extent compared to un-filled sample. However, an increase in izod impact and bending strengths has been observed. The results of this investigation demonstrate that powder coating wastes with thermoset structure can be used as fillers in LDPE.
AtıfScopus13WoS15OpenAlex16İncele - MakaleAçık Erişim2021Scopus SJRQ1Chemical profiling and biological evaluation of nepeta baytopii extracts and essential oil: An endemic plant from turkey
Zengin, Gokhan; Mahomoodally, Mohamad Fawzi; Aktumsek, Abdurrahman; Jekő, József; Cziáky, Zoltán; Rodrigues, Maria João; Custodio, Luisa; Polat, Rıdvan; Cakilcioglu, Ugur; Ayna, Adnan
Nepeta baytopii is a poorly studied, endemic Nepeta species (Lamiaceae) of Turkey. For the first time, the biological activities (antioxidant, enzyme inhibition, and cytotoxicity properties) of the hexane, ethyl acetate, methanol, water/methanol, and water extracts and essential oil prepared from N. baytopii aerial parts were assessed. Hydro-methanol (41.25 mg gallic acid equivalent (GAE)/g) and water extracts (50.30 mg GAE/g), respectively showed the highest radical scavenging (94.40 and 129.22 mg Trolox equivalent (TE)/g, for 2,2-diphenyl-1-picrylhydrazyl radical and 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid radical scavenging assays) and reducing (229.37 and 129.55 mg TE/g, for ferric-reducing antioxidant power and cupric-reducing antioxidant capacity assays) capacities in vitro. An interestingly high inhibition was observed for ethyl acetate extract against butyrylcholinesterase (10.85 mg galantamine equivalent/g). The methanol extract showed high cytotoxicity (31.7%) against HepG2 cells. Caryophyllene oxide was identified in high concentrations in the essential oil (39.3%). Luteolin and apigenin and their derivatives were identified from the methanol and water extracts. The results obtained from this study highlighted that the abundance of highly bioactive compounds from Nepeta baytopii ensures the multiple biological activities of the tested extracts, and this suggests a potential use in the pharmaceutical and nutraceutical fields, and therefore should be investigated further.
AtıfScopus32OpenAlex32İncele - MakaleYalnız künye2021Scopus SJRQ1Ghost scalar field dark energy models from an extended Kaluza-Klein perspective
Korunur, Murat
Reconstruction process of scalar field models (quintessence, tachyon, dilaton and K-essence), which can be performed by making use of some dark energy density definitions such as holographic, Ricci, new agegraphic and ghost types proposals, has been an interesting and very attractive area to many physicists in literature. In this work, in a five-dimensional framework, we establish a correspondence between the quintessence, tachyon and the dilaton type scalar field definitions and the generalized ghost dark energy model by considering the extended form of the Kaluza-Klein (EKK) gravity. Accordingly, we numerically study the associated equation of state parameters, as well as their kinetic energy and scalar potential terms.
AtıfScopus5WoS5OpenAlex6İncele - MakaleYalnız künye2021Scopus SJRQ3Enzyme inhibition and antioxidant functionality of eleven Inula species based on chemical components and chemometric insights
Ceylan, Ramazan; Zengin, Gokhan; Mahomoodally, Mohamad Fawzi; Sinan, Kouadio Ibrahime; Ak, Gunes; Jugreet, Sharmeen; Cakır, Oguz; Ouelbani, Rayene; Paksoy, Mehmet Yavuz; Yılmaz, Mustafa Abdullah
The members of the genus Inula have been widely used in traditional medicinal. In the present study, 11 Inula species were investigated for their phytochemical composition, antioxidant and enzyme inhibitory effects. While quinic acid was the principal compound in I. anatolica, I. britannica, I. inuloides, I. oculus-christi, I. peacockiana, I. sechmenii, I. thapsoides and I. viscidula extracts (22.43–42.02 mg/g dry extract (DE)), I. aucheriana and I. discoidea extracts contained rutin as their most abundant compound (23.28 and 79.10 mg/g extract, respectively). Interestingly, all the Inula extracts were active inhibitors of the five key clinical enzymes (acetylcholinesterase (3.56–5.13 mg galantamine equivalent (GALAE)/g), butyrylcholinesterase (1.49–7.34 mg GALAE/g), tyrosinase (112.31–122.13 mg kojic acid equivalent (KAE)/g), α-glucosidase (0.77–2.08 mmol acarbose equivalent (ACAE)/g) and α-amylase (0.73–0.90 mmol ACAE/g)). Furthermore, the extracts were observed to exhibit substantial antioxidant capacity (1,1-diphenyl-2-picrylhydrazyl (DPPH): 58.99–188.22 mg trolox equivalent (TE)/g); 2,2-azino-bis(3-ethylbenzo-thiazoline-6-sulfonic acid) (ABTS): 90.51–220.97 mg TE/g; cupric reducing antioxidant capacity (CUPRAC): 169.88–460.53 mg TE/g; ferric reducing antioxidant power (FRAP): 81.57–237.99 mg TE/g; metal chelating activity: 8.31–25.39 mg ethylenediamine tetraacetate equivalent (EDTAE)/g; phosphomolybdenum: 1.55–2.49 mmol TE/g). In conclusion, the Inula species studied herein showed promising pharmacological potentials justified by the presence of a panoply of bioactive compounds.
AtıfScopus60OpenAlex60İncele - MakaleYalnız künye2021Scopus SJRQ2Structural, photovoltaic and optoelectronic properties of graphene–amorphous carbon nanocomposite
Aslan, Naim
Reduced graphene oxide–amorphous carbon nanocomposites were coated on p-Si wafers to prepare graphene-based photodiodes or photodetectors. Electrophoretic deposition was used to prepare electronic devices. Scanning electron microscopy, energy-dispersive spectra, X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy were used in the morphological and structural characterization. Characterization methods confirm that deposited films are in reduced graphene oxide–amorphous carbon nanocomposite structure. Photoresponsive characteristics were checked using I–V, I–t and C–t techniques. It was seen that diodes are responsive to illumination where increased photocurrent and photocapacitance were obtained for increased illumination intensity. Electrical properties were assessed; C–V, G–V properties were found to depend on AC signal frequency. Signal frequency-dependent behavior was attributed to interface states. The density of interface states was calculated, and it was seen that the density of interface states increases with increasing AC signal frequency. It was illustrated that electrical characteristics of photodiodes were affected by signal frequency and the density of interface states.
AtıfScopus15WoS15OpenAlex18İncele - MakaleAçık Erişim2021Scopus SJRQ2Evaluation of chemical constituents and biological properties of two endemic Verbascum species
Zengin, Gokhan; Mahomoodally, Mohamad Fawzi; Sinan, Kouadio Ibrahime; Sadeer, Nabeelah; Maggi, Filippo; Caprioli, Giovanni; Angeloni, Simone; Mollica, Adriano; Stefanucci, Azzurra; Ak, Gunes
Members from the Verbascum genus are well appraised for their traditional uses against a variety of ailments including anti-inflammatory related disorders. This study thus attempts at validating the biological properties of two underexplored Verbascum members namely Verbascum euphraticum Benth. (V. euphraticum) and Verbascum oocarpum Murb. (V. oocarpum) in terms of their antioxidant and enzymatic inhibitory activities. Concentration of specific bioactive compounds was also established and molecular dynamic analysis were conducted on amassed data. Results showed that total phenolic and total flavonoid contents were higher for the methanolic extract of V. oocarpum compared to the methanolic extract of V. euphraticum. Phytochemical quantification revealed that the extraction solvents influenced the phytochemical composition of the extracts. Derivatives of phenolic acids such as 3-caffeoylquinic acid and 3,5-dicaffeoylquinic acid together with some phenolic acids i.e., gallic, vanillic, caffeic, syringic, p-coumaric and ferulic acid, have been detected in the extracts of both Verbascum species. Methanolic extracts of V. euphraticum and V. oocarpum yielded the highest total content of monitored compounds resulting in 162.758 and 3716.861 μg/g of dried weight extract, respectively. The methanolic extracts of both plants showed highest antioxidant potential while the ethyl acetate and hexane extracts were potent inhibitors of cholinesterase, α-amylase and α-glucosidase. Molecular dynamic results indicated that vanillic acid is able to make strong interactions with copper ions of tyrosinase, resulting into an effective anti-tyrosinase activity. In light of the above, both Verbascum species could be considered for future phytopharmaceutical development.
AtıfScopus36OpenAlex36İncele - MakaleYalnız künye2021Opinions of coaches regarding their professional self-efficacy in Elazig province
Namli, Aysel Kizilkaya; Kizilkoca, Mustafa
This research was carried out in order to determine the opinions of the coaches in Elazig province regarding their professional self-efficacy. Qualitative research model was used in the research and case study was used from qualitative research models. The study group consists of 30 coaches who are still actively coaching in Elazig province, which was created with the maximum variety method of the purpose sample included in non-selective sampling methods. A semi-structured interview form was used to collect data in the research. In the analysis of the data obtained as a result of the research; descriptive analysis was used in the creation of themes and content analysis was used to analyze the answers. The coaches stated various opinions such as that their profession is a special field, entertaining, personal development provider, health protection in the research. The research concluded that all coaches need to improve themselves. Besides, coaches think that professional development has an impact on personal development. According to the results of the research, the strengths of the coaches are such characteristics as being patient, being willing, being conscientious, loving the profession, being ambitious, being tolerant; features such as having communication problems, getting angry quickly, being sensitive and emotional are determined as the weakest aspects.
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