Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleYalnız künye2023Scopus SJRQ2
    Physicochemical Properties for Food Packaging and Toxicity Behaviors Against Healthy Cells of Environmentally Friendly Biocompatible Starch/Citric Acid/Polyvinyl Alcohol Biocomposite Films

    Gürler, Nedim; Paşa, Salih; Erdoğan, Ömer; Cevik, Ozge

    The current study focuses on the fabrication, characterization, and cytotoxic effects of polymeric biocomposite films composed of starch, various concentrations of citric acid (3%, 6%, and 9%), and polyvinyl alcohol. The cross-linked corn starch (S)-polyvinyl alcohol (P) biocomposite films are prepared by casting technique using glucose (G) and fructose (F) as plasticizers. The chemical structure of obtained films is characterized by Fourier transform infrared and x-ray diffraction. Physicochemical parameters of the films such as solubility, swelling capacity, and water vapor permeability, optical and mechanical properties are investigated. Furthermore, the cytotoxicity is evaluated to determine the biocompatibility of samples. The physicochemical properties of S-P(Starch-Polyvinyl alcohol) films improve with the addition of citric acid during the esterification reaction. The tensile strength for Starch-Polyvinyl alcohol-Glucose blend composition with 3% citric acid (SPG3) and Starch-Polyvinyl alcohol-Fructose blend composition with 3% citric acid (SFG3) biocomposite films is determined as 10.17 and 8.24 MPa, respectively, compared to 8.16 and 7.94 MPa for without citric acid, respectively. The cell viability values of biocomposite films towards NIH-3T3 and L929 cells are calculated 90% compared to the control group. Thus, it demonstrates that they are also quite biocompatible materials.

    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus34WoS37OpenAlex37
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2023Scopus SJRQ3
    Structural, physical, and radiation absorption properties of a significant nuclear power plant component: A comparison between REX-734 and 316L SS austenitic stainless steels

    Say, Yakup; Güler, Ömer; Kavaz, Esra; ALMisned, Ghada; Ene, Antoaneta; Tekin, Huseyin Ozan

    Austenitic stainless steels (SSs) are commonly used as in-core and surrounding structural materials in today’s industrial BWR and PWR systems. Such adaptable steels have also been the primary materials studied and used in several advanced nuclear reactor technologies, such as fast breeding and magnetic fusion reactors. In this study, some critical material properties, such as structural, physical, and radiation-shielding properties of REX-734 and 316L SS, were experimentally evaluated and compared to those of a number of other alloys. In addition to homogeneous element distribution, both alloys exhibit strong crystal orientation. The REX-734 alloy has a tensile strength of 1,259 MPa, whereas the 316L SS alloy has a tensile strength of 495 MPa. Moreover, nitrogen in the REX-734 alloy formed ultra-hard nitrides with Cr, Nb, and Si and precipitated into the structure and increased the strength. According to our findings, the mass attenuation coefficient values of the 316L SS sample were slightly higher than those of the REX-734 sample at all energies. It can be concluded that the REX-734 sample, with its exceptional strength qualities and excellent radiation attenuation capabilities, may be a viable nuclear power plant material for future investigations.

    AtıfScopus7
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2023Scopus SJRQ2
    Analysis of awareness of gynaecological cancers İn women using social media

    Alp Dal, Nursel; Gümüşsoy, Süreyya; Ertem, Gül

    This study aimed to use social media to investigate the relationship between the demographic, obstetric and gynaecological characteristics and the awareness of gynaecological cancer among women. The data were collected between 1st March and May 2018 using an internet-baseline survey/surveymonkey/google form. The sample was consisted of 1227 women who were literate, active social media users and had volunteered to participate in the study via social media. The GCAS scores of women who were in the age range 20–24 years, primary school graduates, no social security, were not pregnant, had a miscarriage, did not examine their external genital organs, had not entered the menopause and who did not use any family planning methods, were lower than the other women. The GCA of the women was found to be high.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    • SDG 5 · Toplumsal Cinsiyet Eşitliği
    AtıfScopus3WoS2OpenAlex5
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2023Scopus SJRQ3
    Investigation of thermophysical properties of synthesized SA and nano-alumina reinforced polyester composites

    Şahal, Hakan; Aydoğmuş, Ercan; Arslanoğlu, Hasan

    Synthesis and characterization of 4-[(E)-(5-bromo-2-hydroxybenzylidene) amino]-N-(4-methylpyrimidin-2-yl) benzenesulfonamide (SA) has been performed. Alumina (Al2O3) and SA reinforced polyester composites are synthesized, and characterization processes are carried out. SA formed has been characterized by Fourier transform infrared (FTIR) spektrofotometre and nuclear magnetic resonance (NMR) spectroscopy. The thermal decomposition behavior of the nanocomposites in a nitrogen environment under non-isothermal conditions from 298 to 973 K is investigated with proportional-integral-derivative (PID) system. Thermal conductivity, Shore D hardness, and thermal decomposition behaviors of the nanocomposites that are added with alumina filler and synthesized with SA reinforcement have been compared. Nano-alumina filler raises the thermal conductivity coefficient and Shore D hardness of the polyester composites. The addition of synthesized SA reduces both the thermal conductivity coefficient and Shore D hardness. The thermal conductivity coefficient has been measured at the lowest in the pure polyester (0.056 W/m·K), and highest in the nano-alumina reinforced composite (0.072 W/m·K). The lowest Shore D hardness (nearly 68) is determined in the synthesized SA reinforced composite. Also, the experimental study has been optimized with the help of response surface methodology (RSM), and the improved theoretical models have been evaluated by statistical analysis.

    AtıfScopus5WoS6OpenAlex13
    ScopusWeb of Scienceİncele
  • MakaleYayıncıda açık erişim2023Scopus SJRQ4
    Family Physician’s Opinions and Recommendations on the Family Medicine Practices

    Baş, Kazım

    Objectives: This study aims to evaluate the opinions and recommendations of family physicians working in family health centers regarding the practices of family medicine. Methods: This descriptive research was conducted with 307 family physicians working in family health centers of Elazığ and Muş provinces located in the east of Turkey between September and November 2021. The sample of this study was comprised of 193 (62.9%) family physicians who were available during the study period. The questionnaire created by the researcher was used to collect with the face-to-face interview technique and/or Google Forms data. Results: A total of 193 family physicians were included in the study. The mean age of the family physicians was 41.4±8.5 years, and their mean population was 3138.1±534.1 people. Of the family physicians, 184 (95.3%) stated professional devaluation, 179 (92.7%) excessive workload, the problems arising from the legislation, 173 (89.6%) performance, 158 (81.9%) the excess of the population to be served, 155 (80.3%) financial problems, coordination problems with senior management, 132 (68.4%) inadequate with the physical structure of the building and equipment, and 125 (64.8%) stated the insufficient number of non-physician personnel were among the factors negatively affecting work in family health centers. In addition, 180 (93.2%) family physicians stated that changes are needed in existing family medicine practices. Conclusion: According to the study results, there are negative situations that affect the effective and efficient implementation of family medicine practices. The current policy needs to be revised to carry out family medicine practices effectively and efficiently.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus2OpenAlex2TR Dizin2
    ScopusTR Dizinİncele
  • MakaleYalnız künye2023Scopus SJRQ1
    Mathematical modeling of vibration failure caused by balancing effect in hydraulic turbines

    Kahraman, Gökhan; Özdemir, Osman

    This article discusses the causes of vibrations depending on unbalanced hydraulic forces in rotating and non-rotating equipment in hydraulic plants within the scope of vibration measurement standards. The radial and axial positions of the turbine shaft, normal operating conditions, the absolute vibration of the signal output velocity during startup and shutdown during unbalance condition of the turbine, the proximity probes have been measured by TMO 793 accelerometer sensor and TMO 793 velocity sensor. The results obtained from the monitoring are analyzed and the first discussion is over the comparison of the current operating levels and vibration standards. Secondly, the comparison is analyzed in order to examine the improvement in vibration level of the elimination of hydraulic imbalance more comprehensively, considering the stability of the hydro turbine-generator unit, a proportional row damping force, proportional-order oil-film force and a hydraulic force and by creating a new non-linear proportional-order mathematical model. Changes in vibration levels and spectral bands for failure types are stated as well. The solution of this integrated and accurate mathematical model shows that it is useful and concise in the diagnosis and prediction of faults in hydropower plants.

    AtıfScopus13WoS13OpenAlex16
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  • MakaleYayıncıda açık erişim2023Scopus SJRQ3
    Potassium chloride recovery from mechanically activated microcline through the chlorination roasting and leaching route

    Alyosif, Bahaa; Uysal, Turan; Erdemoğlu, Murat

    In this study, effects of mechanical activation in the chlorination roasting and water leaching route known as CaCl2 process and developed for the production of potassium chloride (KCl) from potassium feldspar ores were studied. A microcline containing K-feldspar ore with 10.89% K2O was first intensively dry milled by a planetary ball mill and mixed with calcium chloride (CaCl2) and then roasted at temperatures up to 1000 °C to obtain KCl that will be finally dissolved by the water leaching. Potassium recovery by water leaching increased rapidly up to 800 °C. At higher temperatures, the recovery decreased fast due to the evaporation of KCl. According to the K recovery values per unit energy consumed, the optimum roasting temperature was determined as 750 °C and the milling time was 15 min. It was concluded that intensive milling causes mechanical activation of the microcline to reduce the chlorination roasting temperature, which triggers a rise in the K recovery by the water leaching.

    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus9WoS8OpenAlex7
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2023Scopus SJRQ4
    Relationship between loneliness, hopelessness and social support experienced by mothers with disabled children

    Baş, Nazan Gürarslan; Karatay, Gülnaz; Baş, Kazım

    The aim of the study was to evaluate the relationship between loneliness, hopelessness and social support experienced by mothers with disabled children. This cross-sectional study was conducted with 106 mothers with disabled children. The data was collected by compiling the Personal Information Form and by applying three main scales: the UCLA Loneliness Scale (UCLA-LS), the Beck Hopelessness Scale (BHS) and the Multidimensional Scale of Perceived Social Support (MSPSS). The data obtained was analyzed using the number, percentage, mean, correlation, T test, Anova and Mann Whitney U tests. The UCLA-LS mean score of the mothers was 50.56 ± 11.94, the BHS mean score was 10.78 ± 4.93 and the MSPSS mean score was 40.97 ± 13.86. The results showed a positive correlation between the mean scores of the loneliness and hopelessness scale, and a negative correlation between the mean scores of the loneliness and hopelessness scale and the mean MSPSS score (p <.05). As a result of the research findings, mothers with disabled children experienced loneliness and hopelessness and did not receive sufficient social support.

    AtıfScopus2WoS2
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  • BildiriYalnız künye2023
    Investigation of corrosion behavior of ZrN-based PVD coatings on Ti-29Nb-13Ta-4.6Zr alloy in Hank's solution

    Ali, Leila Ait; Aslan, Naim; Yilmazer, Hakan; Niinomi, Mitsuo; Sen, Anil; Dikici, Burak; Benhala, B.; Raihani, A.; Mansouri, K.; Qbadou, M.

    In this study, the TiNbTaZr (TNTZ) alloys, which do not contain toxic and allergic elements, have been coated with hard ZrN physical vapor deposition (PVD) coatings to increase their in-vitro corrosion resistance. In-vitro electrochemical behavior of the ZrN coating and uncoated TNTZ alloy was evaluated using open circuit potential (OCP) and potentiodynamic polarization (PDS) techniques, respectively. The characterizations of the coatings were carried out using scanning electron microscopy (SEM), energy dispersion spectroscopy (EDS), and X-ray diffraction (XRD). The SEM examinations showed that ZrN coating is homogeneous. Besides, ZrN coating had a higher corrosion resistance than uncoated TNTZ alloy in Hank's solution.

  • MakaleAçık Erişim2023Scopus SJRQ3
    The effect of different boron compounds on nutrient digestibility, intestinal nutrient transporters, and liver lipid metabolism

    Şahin, Emre; Orhan, Cemal; Erten, Füsun; Şahin, Fikrettin; Şahin, Nurhan; Şahin, Kazim

    Background/aim: Gastrointestinal health is essential for maintaining a healthy lifestyle. Improving nutrient absorption and energy metabolism are the critical targets for intestinal health. This study aimed to determine the effects of different boron (B) derivatives on nutrient digestibility, intestinal nutrient transporters, and lipid metabolism in rats. Materials and methods: Twenty-one rats were allocated to three groups (n = 7) as follows: (i) Control, (ii) Sodium pentaborate pentahy-drate (SPP), and (iii) boric acid (BA). The rats were fed a chow diet (AIN-93M) and supplemented with 8 mg/kg elemental B from SPP (45.2 mg/kg BW) and BA (42.7 mg/kg BW) via oral gavage every other day for 12 weeks. The nutrient digestibility of rats in each group was measured using the indigestible indicator (chromium oxide, Cr2 O3, 0.20%). At the end of the experiment, animals were decapitated by cervical dislocation and jejunum, and liver samples were taken from each animal. The nutrient transporters and lipid-regulated transcription factors were determined by RT-PCR. Results: The nutrient digestibility (except for ash) was increased by SPP and BA supplementation (p < 0.05). SPP and BA-supplemented rats had higher jejunal glucose transporter 1 (GLUT1), GLUT2, GLUT5, sodium-dependent glucose transporter 1 (SGLT1), fatty acid transport protein-1 (FATP1), and FATP4 mRNA expression levels compared to nonsupplemented rats (p < 0.0001). BA-supplemented rats had remarkably higher peroxisome proliferator-activated receptor gamma (PPARγ) levels than nonsupplemented rats (p < 0.0001). In contrast, sterol regulatory element-binding protein 1c (SREBP-1c), liver X receptor alpha (LxR-α), and fatty acid synthase (FAS) levels decreased by SPP supplementation compared to other groups (p < 0.05). Conclusion: SPP and BA administration enhanced nutrient digestibility, intestinal nutrient transporters, and liver lipid metabolism in rats.

    • SDG 2 · Açlığa Son
    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus8WoS7OpenAlex9TR Dizin1
    ScopusWeb of SciencePubMedTR Dizinİncele
  • MakaleAçık Erişim2023Scopus SJRQ2
    Expression of phoenixin-14 and nesfatin-1 in the hypothalamo–pituitary–gonadal axis in the phases of the estrous cycle

    Parlak Ak, Tuba; Yaman, Mine; Bayrakdar, Ali; Bulmus, Ozgur

    Phoenixin-14 (PNX-14) and nucleobindin 2 (NUCB2)/nesfatin-1 are regulatory neuropeptides expressed in the hypothalamus. These neuropeptides can be effective in hormonal regulation of the hypothalamo–pituitary–gonadal (HPG) axis and reproductive functions. In the present study, the distribution of PNX-14 and NUCB2/nesfatin-1 in the hypothalamus, pituitary, ovary, and uterus tissues during the phases of the estrous cycle in female rats was investigated. Eighteen Wistar Albino rats determined among animals showing regular estrous cycle by vaginal smear method were divided into three groups: proestrus (Group I), estrus (Group II) and diestrus (Group III). Serum gonadotropin-releasing hormone (GnRH), plasma PNX-14, and NUCB2/nesfatin-1 concentrations were the highest, moderate, and lowest in estrus, diestrus, and proestrus phases, respectively. PNX-14 immunoreactivity in the supraoptic and arcuate nuclei of the hypothalamus and NUCB2/nesfatin-1 immunoreactivity in the paraventricular nuclei were particularly evident in the estrus phase. These neuropeptide immunoreactivities were decreased in different cells of anterior pituitary during proestrus compared with those during estrus and diestrus. PNX-14 immunoreactivity in the ovary, especially during the estrus phase, was diffuse and intense in the granulosa and luteal cells and oocytes, and it was few and weak in theca cells. In addition, NUCB2/nesfatin-1 immunoreactivity was abundant and strong in granulosa and luteal cells, theca and interstitial cells, and oocytes during estrus. In the estrus phase, PNX-14 immunoreactivity was strong in the glandular epithelial cells and stromal cells of the endometrium, also NUCB2/nesfatin-1 immunoreactivity was strong in the epithelial and glandular epithelial cells. As a result, when the estrous cycle was evaluated, it was concluded that the changes in the distribution of PNX-14 and NUCB2/nesfatin-1 at all phases were related to GnRH and that these neuropeptides showed the highest immunoreactivity especially in the HPG axis and uterus tissues of estrus rats.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus21OpenAlex22
    ScopusPubMedİncele
  • MakaleYalnız künye2023Scopus SJRQ2
    A novel electrochemical sensor for metoprolol analysis based on glutardialdehyde–zinc oxide modified boron doped diamond electrode

    Koçak, Berna; İpek, Yeliz; Keçeci, Ali

    In this study, glutardialdehyde–zinc oxide modified boron doped diamond electrode (GA2–ZnO/BDDE) was developed as a new electrochemical sensor for the rapid, sensitive and selective determination of metoprolol (MTP). By using boron doped diamond electrode (BDDE), glutardialdehyde modified boron doped diamond electrode (GA2/BDDE) and glutardialdehyde–zinc oxide modified boron doped diamond electrode (GA2–ZnO/BDDE) separately, the electrochemical behavior of MTP on the surfaces of these electrodes was determined by applying cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. According to the results, the linear working range was 9.99 × 10−7–3.85 × 10−5 mol·L−1 and the limit of detection (LOD) was 7.53 × 10−8 mol·L−1 in pH 7 Britton–Robinson buffer solution. In addition, intraday reproducibility of peak current and peak potential were measured on the GA2–ZnO/BDDE surface and the results were calculated as 0.56 and 1 (RSD%), respectively. In order to investigate the reproducibility of GA2–ZnO/BDDE, 5 different modified electrodes were prepared with the same composition and conditions. The interday repeatability of the modified electrode was calculated as 3.13 (RSD%) and 1.05 (RSD%) for interday peak current and peak potential, respectively. The applicability of this method was confirmed by analysis of commercial drug tablets containing MTP as active ingredient. The mean recovery of the developed sensor was 95.6 % ± 1.7.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus14WoS12OpenAlex13
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2023Scopus SJRQ3
    Bioremediation of herbicide diquat dibromide from aqueous solution with white rot fungus Phanerochaete chrysosporium

    Yildirim, Numan; Ciftci, Emine; Erguven, Gokhan Onder; Durmus, Barbaros

    In this study, the fungal bioremediation of herbicide diquat dibromide (DD) by white rot fungus Phanerochaete chrysosporium was studied. After bioremediation, the reduction in toxicity of the remediated media was evaluated by Daphnia magna as a model organism. For bioremediation studies, flask-level batch experiments were performed at different DD concentrations (10, 20 and 50 ppm) under static and agitated conditions. The highest reduction rates of chemical oxygen demand and total organic carbon were determined as 85.92 (for 20 ppm DD) and 87.46% (for 10 ppm DD), respectively under agitated conditions. After bioremediation, D. magna bioassay was used for toxicity assessment during 24, 48 and 72-h periods. In current study, it was observed that P. chrysosporium has very effective bioremediation capacity for diquat dibromide. The D. magna bioassay revealed that P. chrysosporium provides effective reduction in toxicity of diquat dibromide.

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 12 · Sorumlu Üretim ve Tüketim
  • Kitap BölümüAçık Erişim2023Scopus SJRQ4
    The Effects of Knowledge Extraction Approaches on Cryptanalysis Studies and Analysis of the Success of Chaos-Based Countermeasures

    Bürhan, Yücel; Özkaynak, Fatih

    Each new approach and scientific progress provides many advantages and innovations from theory to practice yet, its disadvantages should be evaluated comprehensively from different perspectives. In this study, the effects of knowledge extraction approaches on the cryptanalysis process have been evaluated. It is known that the secret key of the encryption algorithm can be obtained by using knowledge extraction approaches, especially with application oriented attacks such as side channel analysis. It is known that chaotic masks can be used as a countermeasure to prevent the success of these attacks. In this study, side-channel analyzes of the chaos-based substitution box structures that have been proposed in recent years have been carried out. The side channel analysis results of the existing studies in the literature have been carried out for the first time in this study. The results obtained showed that the approaches in the field of knowledge extraction should be handled more comprehensively in the cryptanalysis processes, and also pointed out that a new evaluation criterion should be analyzed for future studies for chaos-based design studies.

    AtıfScopus2OpenAlex2
    Scopusİncele
  • MakaleYalnız künye2023Scopus SJRQ1
    Analysis of the mechanical behavior and prediction of the plastic zone of a large-diameter buried gas pipeline under ground overload

    Xu, Qian; Zhong, Liqiong; Shu, Mengjie; Zou, Zhenwei; Yang, Gang; Zheng, Qiang; Chen, Xingli; Akkurt, Nevzat; Zhang, Hui; Qiang, Yujie

    Plastic failure of pipelines caused by ground overload is increasing. The one-dimensional model based on mechanical nodal parameters cannot predict the plastic failure characteristics of the three-dimensional structure of the pipeline. In order to predict the evolution of the plastic failure of the pipeline with the yield strength as the evaluation criterion, a multidimensional model is needed to consider the changes in the external loads and the changes in the mechanical properties of the pipeline along the circumferential and axial directions. In this study, a finite element calculation model for a large-diameter gas pipeline underground overload was established to investigate the law of stress change in the plastic zone. The nonlinear surface fitting method was used to establish the angle fitting model of the plastic zone and the depth fitting model of the plastic zone. The variation of the area of the plastic zone was described, and the reliability of the results was verified. In addition, the accuracy of the fitting model and the cost of the finite element calculation were evaluated. The results showed that the pipeline entered plasticity at a ground load of P = 25 MPa, and the plastic zone developed continuously in the axial and circumferential directions as the ground load increased. The angle and depth increased to 36° and 1.8 m, respectively, at P = 50 MPa. The average absolute errors for the plastic zone depth fitting model and the plastic zone angle fitting model were 6.42% and 6.64%, respectively, both of which can provide an accurate description of the plastic zone. The calculation results of the plastic zone angle fitting model could meet requirements of data processing and analysis. The plastic zone depth fitting model could be used to obtain solutions with higher accuracy, but it increases the cost of finite element simulation.

    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
    AtıfScopus6OpenAlex6
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2023Scopus SJRQ1
    Effects of a Combination of Arginine Silicate Inositol Complex and a Novel Form of Biotin on Hair and Nail Growth in a Rodent Model

    Demir, Betul; Cicek, Demet; Orhan, Cemal; Er, Besir; Erten, Fusun; Tuzcu, Mehmet; Ozercan, Ibrahim Hanifi; Sahin, Nurhan; Komorowski, James; Ojalvo, Sara Perez

    The purpose of this study was to examine the effects of a combination of inositol-stabilized arginine silicate complex (ASI) and magnesium biotinate (MgB) on hair and nail growth in an animal model. Twenty-eight female Sprague–Dawley rats (8 weeks old) were randomized into one of the following groups: (i) group (control), shaved; (ii) group (ASI), shaved + ASI (4.14 mg/rat/day); (iii) group (ASI + MgB I), shaved + ASI (4.14 mg/rat/day) + MgB (48.7 μg/rat/day); and (iv) group (ASI + MgB II), shaved + ASI (4.14 mg/rat/day) + MgB (325 μg/rat/day). On day 42, compared with the control group, while hair density (p < 0.05, p < 0.01, and p < 0.0001, respectively) and anagen ratio (p < 0.01, p < 0.01, and p < 0.001) increased in the ASI, ASI + MgB I, and ASI + MgB II groups, telogen ratio decreased (p < 0.01, p < 0.01, and p < 0.001, respectively). In the molecular analysis, VEGF, HGF, and KGF-2 increased in the ASI (p < 0.01, p < 0.01, and p < 0.05, respectively), ASI + MgB I (p < 0.0001 for all), and ASI + MgB II (p < 0.0001 for all) groups when compared to the control group. FGF-2 (p < 0.01) and IGF-1 (p < 0.001) were found to be increased in the ASI + MgB I and ASI + MgB II groups. SIRT-1 and β-catenin increased in the ASI (p < 0.05 and p < 0.01), ASI + MgB I (p < 0.001 for both), and ASI + MgB II (p < 0.0001 for both) groups. Wnt-1 increased in the ASI + MgB I (p < 0.001) and ASI + MgB II (p < 0.0001) groups. In conclusion, the combination of ASI and MgB could promote hair growth by regulating IGF-1, FGF, KGF, HGF, VEGF, SIRT-1, Wnt, and β-catenin signal pathways. It was also established that ASI did not affect nail growth, whereas the MgB combination was effective using a higher dose of biotin.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus11WoS9OpenAlex11
    ScopusWeb of SciencePubMedİncele
  • MakaleYalnız künye2023Scopus SJRQ3
    A goodness-of fit improvement based on τ-preserving transformation for semiparametric family of copulas

    Susam, Selim Orhun; Hudaverdi, Burcu

    In this paper, we study on improving the goodness-of fit for the data by using τ-preserving transform for the semiparametric family of bivariate copulas. We estimate the generator function (Formula presented.) using the Bézier polynomial function and define τ- preserving transformation on the generator function under positive quadrant dependence assumption. We investigate the performance of our methodology on real data example contained life expectancy study. The findings indicate that the model fitting is improved by using τ- preserving transformation.

    AtıfScopus3WoS3OpenAlex2
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  • MakaleAçık Erişim2023Scopus SJRQ4
    Deep Learning Based Classification for Hoverflies (Diptera: Syrphidae)

    Utku, Anıl; Ayaz, Zafer; Ciftci, Derya; Ali Akcayol, M.

    Syrphidae is essential in pollinating many flowering plants and cereals and is a family with high species diversity in the order Diptera. These family species are also used in biodiversity and conservation studies. This study proposes an image-based CNN model for easy, fast, and accurate identification of Syrphidae species. Seven hundred twenty-seven hoverfly images were used to train and test the developed deep-learning model. Four hundred seventy-nine of these images were allocated to the training set and two hundred forty-eight to the test dataset. There are a total of 15 species in the dataset. With the CNN-based deep learning model developed in this study, accuracy 0.96, precision 0.97, recall 0.96, and f-measure 0.96 values were obtained for the dataset. The experimental results showed that the proposed CNN-based deep learning model had a high success rate in distinguishing the Syrphidae species.

    AtıfScopus3WoS3OpenAlex3TR Dizin1
    ScopusWeb of ScienceTR Dizinİncele
  • MakaleYalnız künye2023Scopus SJRQ3
    MOLECULAR CHARACTERIZATION OF Dittrichia viscosa (L.) GREUTER (ASTERACEAE) POPULATIONS REVEALED BY ISSR MARKERS AND CHLOROPLAST (cpDNA) trnL INTRON SEQUENCES; [MOLEKULARNA KARAKTERIZACIJA POPULACIJA Dittrichia viscosa (L.) GREUTER (ASTERACEAE) POMOĆU ISSR MARKERA I HLOROPLAST (cpDNA) trnL INTRONSKIH SEKVENCI]

    Sevindik, Emre; Bozkurt, Makbule; Yilmaz, Mehmet; Şenyüz, Ezginur; Paksoy, Mehmet Yavuz

    In this study, molecular characterization of Dittrichia viscosa (L.) Greuter populations collected from Aydın province was carried out based on ISSR technique and chloroplast DNA trnL intron sequences. 10 ISSR primers were used to determine the molecular characterization among the populations. For cpDNA trnL intron amplification, trnC and trnD primers were used. In ISSR analysis, a total of 70 bands were obtained. The polymorphism rate was determined to be approximately 94.28%. According to the ISSR analysis, the UPGMA dendrogram consisted of three groups. For cpDNA trnL intron sequences, phylogenetic analyses were obtained along with genetic distances. For populations, cpDNA trnL intron sequences were determined between 454 and 472 bases. The maximum likelihood phylogenetic tree consist of two clades. In addition, cpDNA trnL intron sequences of some species (Chrysophthalmum Pulicaria Inula Jasonia Stenachaenium Carpesium Blumea Iphiona Limbarda Rhanterium Lifago Duhaldea Chiliadenus) of Asteraceae family from NCBI with Dittrichia viscosa populations phylogenetic tree was constructed. As a result of the study, it was determined that the polymorphism rate of Dittrichia viscosa populations obtained by ISSR-PCR was higher than the results obtained from trnL intron sequences.

    AtıfScopus3WoS4
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2023Scopus SJRQ3
    Mechanical property and structural-elemental analysis of marine bivalve mollusc shells: Cerastoderma edule, Chamelea gallina, Donax trunculus, Ruditapes decussatus

    Kocabaş, Filiz Kutluyer; Kocabaş, Mehmet; Çanakçi, Aykut; Karabacak, A. Hasan

    Mussels have great annual production in the world and their shells are discarded as a waste. Shells are calcium and carbon accumulators and, formed as a consequence of calcium carbonate biomineralisation. They can be used as bio‐based composite materials in different fields. Hence, assessment of the chemical compound content and microstructure of shells is important for the prospective utility. For these reasons, structure of Cerastoderma edule, Chamelea gallina, Donax trunculus, Ruditapes decussatus shells were analyzed with X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FT-IR) and Scanning Electron Microscope-Energy Dispersive Spectroscopy (SEM-EDS). In addition, microhardness was measured in shells. Our results indicated that shells have a flake like structure with irregular grains appearance morphologically at micrometric scale. The fractions of aragonite in particular shells were assessed. EDS analysis showed that Ca, C and O were major elements of C. edule, C. gallina, D. trunculus, R. decussatus in accordance with XRD data. The lowest microhardness (2.68±0.16 GPa) was in D. trunculus while the highest microhardness (4.28±0.32 GPa) was in C. edule.

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