Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Zengin, Gokhan(26)
- Erten, Fusun(20)
- Orhan, Cemal(17)
- Sahin, Kazim(17)
- Gul, Muhammet(15)
- Benzer, Fulya(12)
- Kocabaş, Mehmet(12)
- Aglar, Erdal(11)
- Serdar, Osman(11)
- Akkurt, Nevzat(10)
- Topal, Murat(10)
- Yeşiltepe, Akgün(10)
- Yucesan, Melih(10)
- Danabas, Durali(9)
- Er, Besir(9)
- Kutlu, Banu(9)
- Mahomoodally, Mohamad Fawzi(9)
- Uba, Abdullahi Ibrahim(9)
- Yildirim, Ozal(9)
- Öbek, Erdal(9)
- Acharya, U. Rajendra(8)
- Alp Dal, Nursel(8)
- Cakilcioglu, Ugur(8)
- Kandemir, Fatih Mehmet(8)
- Yildirim, Nuran Cikcikoglu(8)
- Arslan Topal, E. Işıl(7)
- Baloglu, Ulas Baran(7)
- Ozbey, Ulku(7)
- Sahin, Nurhan(7)
- Talo, Muhammed(7)
- Ates, Mehmet(6)
- Attar, Rukset(6)
- Dal, Nursel Alp(6)
- Gümüşsoy, Süreyya(6)
- Gürarslan Baş, Nazan(6)
- Ince, Muharrem(6)
- Kaplan Serin, Emine(6)
- Kutluyer, Filiz(6)
- Ozturk, Burhan(6)
- Aksu, Onder(5)
Yayınlar
- MakaleAçık Erişim2022Scopus SJRQ1Transportation of thermal and velocity slip factors on three-dimensional dual phase nanomaterials liquid flow towards an exponentially stretchable surface
Hussain, Azad; Akkurt, Nevzat; Rehman, Aysha; Alrihieli, Haifaa F.; Alharbi, Fahad M.; Abdussattar, Aishah; Eldin, Sayed M.
The fundamental purpose of this research is to elaborate on slip boundary conditions and the flow of three-dimensional, stable, incompressible, rotating movements of nanoparticles lying across a stretchable sheet. The mathematical model for fluid flow is created using the assumptions stated above. The partial differentials are produced after utilizing boundary layer estimates. The partial differential governing equations are reduced into three coupled ordinary differential equations by using similarity transformations. After, applying transformations the system is solved numerically. Numerical results are approved with the help of the MATLAB bvp4c algorithm. The analysis shows that velocity and temperature are strongly dependent on essential parameters like stretching ratio, velocity slip, rotation, thermal slip parameter, and Prandtl number. Numerical values of distinct parameters on heat flux and skin friction factors are shown in a tabulated form. Partial velocity and thermal slip are applied to the temperature surface. The comparison among the nano-sized particles copper oxide and silver with water base nanofluid affecting velocity and temperature fields are used for analysis. Moreover, the Graphical depiction designates that the velocity and temperature spreading of the thermal slip parameter is increasing. It is observed that Ag-water is the best heat carrier as compared to CuO-water nanofluid.
AtıfScopus15OpenAlex20
İncele - MakaleAçık Erişim2022Scopus SJRQ12D MHD Mixed Convection in a Zigzag Trapezoidal Thermal Energy Storage System Using NEPCM
Abderrahmane, Aissa; Younis, Obai; Al-Khaleel, Mohammad; Laidoudi, Houssem; Akkurt, Nevzat; Guedri, Kamel; Marzouki, Riadh
In a magnetic field, two-dimensional (2D) mixed convection is investigated within a zigzagged trapezoidal chamber. The lower side of the trapezoidal chamber is irregular, in particular, a zigzagged wall with different zigzag numbers N. The fluid particles move in the room due to the motion of the upper wall, while the porosity-enthalpy approach represents the melting process. The thermal parameters of the fluid are enhanced by what is called a nano-encapsulated phase change material (NEPCM) consisting of polyurethane as the shell and a nonadecane as the core, while water is used as the base fluid. In order to treat the governing equations, the well-known Galerkin finite element method (GFEM) is applied. In addition, the heat transfer (HT) and the dynamic behavior of flow are treated in terms of average Nusselt number and contours of streamlines. The main results show that the melt band curve of heat capacity behaves almost parabolically at smaller values of Reynolds number (Re) and larger values of Hartmann number (Ha). Moreover, minimizing the zigzag number is better in order to obtain a higher heat transfer rate.
AtıfScopus30OpenAlex34İncele - MakaleAçık Erişim2022Scopus SJRQ2The effect of COVID-19 restrictions on sleep quality of university students and variables predicting sleep quality
Bulut, Arzu; Sengul, Halil; Uslu, Yeter Demir; Bas, Kazim; Tosun, Nurperihan
BACKGROUND/AIM: The COVID-19 pandemic has created a long period of stress for people worldwide and has significantly affected sleep duration. The pandemic revealed new stress factors that are likely to affect sleep. Uncertainty is a factor that leads to anxiety and depression, which affects sleep. It should also be noted that reductions in sleep quality rather than sleep duration are associated with negative consequences on mental health. This study aims to investigate online that how this situation affected university students. MATERIALS AND METHODS: This research, with a descriptive study design, was conducted in Turkey between June 01, 2021 and July 30, 2021. The sample included 604 people who accepted voluntary participation, chosen by the random selection method. In the study, sociodemographic information form, Pittsburgh sleep quality index (PSQI), morningness-eveningness questionnaire scale (MEQ Scale), Beck depression inventory (BDI), and Beck anxiety inventory (BAI) were used as data collection tools. Pearson correlation analysis was utilized to examine the relationship between the scales. Multiple regression analysis was performed to investigate the role of morningness-eveningness, anxiety, depression, and insomnia severity on sleep quality. RESULTS: Sleep quality was negatively correlated with morningness-eveningness scores (r = -0.32, P < 0.01), and positively and significantly related with anxiety (r = 0.43, P < 0.01), depression (r = 0.40, P < 0.01) and insomnia severity (r = 0.55, P < 0.01). According to regression coefficients, while anxiety (β = 0.041, P < 0.001) and insomnia severity scores (β = 0.226, P < 0.001) positively predicted sleep quality, depression did not predict it significantly (β = 0.009, P > 0.05). A significant difference was found in sleep quality according to morning, evening, and intermediate types (F = 27.401, P < 0.001). CONCLUSION: Events related to the COVID-19 pandemic are associated with reduced sleep quality in connection with increasing negative moods. Considering the importance of sleep for a healthy life, efforts should be made to raise awareness about this issue and to provide psychological help to affected individuals.
AtıfScopus8WoS7OpenAlex10İncele - Derleme MakaleAçık Erişim2022Scopus SJRQ1Dietary exposure to acrylamide: A critical appraisal on the conversion of disregarded intermediates into acrylamide and possible reactions during digestion
Aktağ, Işıl Gürsul; Hamzalıoğlu, Aytül; Kocadağlı, Tolgahan; Gökmen, Vural
The amount of acrylamide in asparagine rich thermally processed foods has been broadly monitored over the past two decades. Acrylamide exposure can be estimated by using the concentration of acrylamide found in foods and alternatively, biomarkers of exposure are correlated. A better estimation of dietary acrylamide exposure is crucial for a proper food safety assessment, regulations, and public health research. This review addresses the importance of the presence of neglected Maillard reaction intermediates found in foods, that may convert into acrylamide during digestion and the fate of acrylamide in the gastrointestinal tract as a reactive compound. Therefore, it is questioned in this review whether acrylamide concentration in ingested foods is directly correlated with the dietary exposure to acrylamide.
AtıfScopus32WoS26OpenAlex31İncele - MakaleAçık Erişim2021Scopus SJRQ2The comparisons of fatty acid composition in some anaerobic gut fungi neocallimastix, orpinomyces, piromyces, and caecomyces
Kar, Bülent; Özköse, Emin; Ekinci, Mehmet Sait
The objective of this study were to identify the fatty acid composition for decanoic (C10:0), tridecanoic (C13:0), myristic (C14:0), pentadecanoic (C15:0), palmitic (C16:0), stearic (C18:0), oleic (C18:1n9c), linoleic (C18:2n6c), arachidic (C20:0), arachidonic (C20:4n6), heneicosanoic (C21:0), erucic (C22:1n9) and Cis-4,7,10,13,16,19-docosahexaenoic (C22:6n3) acids by Neocallimastix, Orpinomyces, Caecomyces and Piromyces species of rumen fungus during in vitro culture. Fatty acid (FA) profile of anaerobic fungi comprises carbon chains of length ranging from 10 to 22 were analyzed as methyl esters. Analysis of fatty acids was performed using Gas Chromatography-Mass Spectrophotometer (GC-MS). FA measures are presented as proportions of relative amounts (% total fatty acid). The highest amounts of fatty acids for all samples were found as myristic (C14:0) acid. The tridecanoic (C13:0) acid represented the second abundant FA in the fungi in all experimental groups. Stearic acid (C18:0) was the third major fatty acid for isolates investigated in the current study. In addition, another fatty acid was palmitic (C16:0) acid with relative amount representing >20% of total FA in all samples. Pentadecanoic (C15:0) acid could not be found in any other samples except Orpinomyces sp. (GMLF5). It is concluded that biohydrogenation of fatty acid composition by anaerobic gut fungi are very variable.
AtıfScopus5WoS3OpenAlex5İncele - MakaleAçık Erişim2021Scopus SJRQ4Regulation of cell signaling pathways by Wogonin in different cancers: Mechanistic review
Butt, Ghazala; Ozbey, Ulku; Malik, Durrshahwar; Attar, Rukset; Youssef, Lara; Farooqi, Ammad Ahmad
Natural products have historically been invaluable as a premium source of therapeutic agents. Recent advancements in genomics and structural biology have portrayed a high-resolution landscape of the diversity of proteins targeted by pharmacologically active products from natural sources. Natural product research has generated valuable wealth of information and cutting-edge research-works have leveraged our conceptual knowledge altogether to a new level. Wogonin (5,7-dihydroxy-8-methoxyflavone) is an O-methylated flavone and has attracted noteworthy appreciation because of its ability to pharmacologically target plethora of cell signaling pathways in different cancers. In this mini-review, we have gathered scattered pieces of available scientific evidence to summarize how wogonin pharmaceutically targeted Wnt/β-catenin, JAK/STAT, VEGF/VEGFR and TRAIL-driven apoptotic pathways in wide variety of cancers. We have also critically analyzed how wogonin prevented carcinogenesis and metastasis in tumor-bearing mice. Although researchers have uncovered pleiotropic role of wogonin in the regulation of different oncogenic signaling cascades but there are visible knowledge gaps in our understanding related to regulation of non-coding RNAs by wogonin. Future studies must converge on the unraveling of additional drug targets for wogonin to achieve a fuller and realistic understanding of the chemopreventive properties of wogonin.
AtıfScopus5WoS6İncele - MakaleAçık Erişim2021Scopus SJRQ3Lutein/zeaxanthin isomers regulate neurotrophic factors and synaptic plasticity in trained rats
Orhan, Cemal; Erten, Füsun; Er, Beşir; Tuzcu, Mehmet; Şahin, Nurhan; Durmaz Kurşun, Öznur Ece; Juturu, Vijaya; Şahin, Kazim
Background/aim: This study was conducted to elucidate the effects of lutein/zeaxanthin isomers (L/Zi) on lipid metabolism, oxidative stress, NF-κB/Nrf2 pathways, and synaptic plasticity proteins in trained rats. Materials and methods: Wistar rats were distributed into four groups: 1) control, 2) L/Zi: rats received L/Zi at the dose of 100 mg/kg by oral gavage, 3) exercise, 4) exercise+L/Zi: rats exercised and received L/Zi (100 mg/kg) by oral gavage. The duration of the study was eight weeks. Results: Exercise combined with L/Zi reduced lipid peroxidation and improved antioxidant enzyme activities of muscle and cerebral cortex in rats (p < 0.001). In the Exercise + L/Zi group, muscle and cerebral cortex Nrf2 and HO-1 levels increased, while NF-κB levels decreased (p <0.001). Also, L/Zi improved BDNF, synapsin I, SYP, and GAP-43 levels of the cerebral cortex of trained rats (p < 0.001). The highest levels of BDNF, synapsin SYP, and GAP-43 in the cerebral cortex were determined in the Exercise+L/Zi group. Conclusion: These results suggested that exercise combined with L/Zi supplementation might be effective to reduce neurodegeneration via improving neurotrophic factors and synaptic proteins, and oxidative capacity in the cerebral cortex.
AtıfScopus15WoS13OpenAlex14
İncele - MakaleYalnız künye2021Scopus SJRQ1Evaluation of the efficiency of chlorpyrifos-ethyl remediation by Methylobacterium radiotolerans and Microbacterium arthrosphaerae using response of some biochemical biomarkers
Onder Erguven, Gokhan; Tatar, Şule; Serdar, Osman; Yildirim, Nuran Cikcikoglu
This study reveals out detoxifying and antioxidant enzyme response of Gammarus pulex exposed/polluted to chlorpyrifos-ethyl insecticide before and after biodegradation/bioremediation by Methylobacterium radiotolerans and Microbacterium arthrosphaerae. Cytochrome P450 1A1, glutathione S-transferase, catalase, and superoxide dismutase activities in G. pulex exposed to chlorpyrifos-ethyl before and after bioremediation/biodegradation by these two bacteria during 24 and 96 h tested by using commercial ELISA kits. The activity of catalase enzyme was decreased depending on chlorpyrifos-ethyl before and after bioremediation/biodegradation the enzyme activity was increased repeatedly. Superoxide dismutase activity level increased after chlorpyrifos-ethyl exposure in 96 h (p > 0.05). Following bioremediation, superoxide dismutase enzyme activity decreased again during 24 h (p > 0.05) and increased during 96 h (p < 0.05). Statistical differences were not found in cytochrome P450 1A1 enzyme activity before and after the process (p > 0.05). No significant differences were determined during the activity of glutathione S-transferase in 24 h (p > 0.05). The activities of glutathione S-transferase were increased after exposure of chlorpyrifos-ethyl during 96 h. After bioremediation; the activity of glutathione S-transferase increased even more (p < 0.05). The results determined that activities of G. pulex at superoxide dismutase, catalase, and glutathione S-transferase are common biomarkers for revealing out the efficiency of bioremediation of chlorpyrifos-ethyl with these two types of soil bacteria. [Figure not available: see fulltext.]
AtıfScopus15WoS14OpenAlex16İncele - MakaleYayıncıda açık erişim2021Scopus SJRQ4Effects of magnesium biotinate supplementation on serum insulin, glucose and lipid parameters along with liver protein levels of lipid metabolism in rats
Sahin, Kazim; Orhan, Cemal; Kucuk, Osman; Erten, Fusun; Tuzcu, Mehmet; Sahin, Nurhan; Ojalvo, Sara Perez; Komorowski, James Richard
The objective of this study was to investigate the effects of a novel form of biotin (magnesium biotinate) on serum glucose, lipid profile, and hepatic lipid metabolism-related protein levels in rats. Forty-two rats were divided into six groups and fed a standard diet-based egg white powdered diet supplemented with either d-biotin at 0.01, 1, or 100 mg/kg BW or magnesium biotinate at 0.01, 1, or 100 mg/kg BW for 35 days. Neither form of biotin influenced (p > 0.05) serum glucose or insulin concentrations. Serum total cholesterol and triglyceride decreased with biotin from both sources (p < 0.05). Concentrations were lower with magnesium biotinate when comparing the 1 mg/kg dose (p < 0.05). Serum, liver, and brain biotin and liver cyclic guanosine monophosphate (cGMP) concentrations were greater when rats were treated with magnesium biotinate versus d-biotin, particularly when comparing the 1 and 100 mg/kg dose groups (p < 0.05). Both biotin forms decreased the liver SREBP-1c and FAS and increased AMPK-a1, ACC-1, ACC-2, PCC, and MCC levels (p < 0.05). The magnitudes of responses were more emphasized with magnesium biotinate. Magnesium biotinate, compared with a commercial d-biotin, is more effective in reducing serum lipid concentrations and regulating protein levels of lipid metabolism-related biomarkers.
AtıfScopus5WoS5OpenAlex5İncele - MakaleAçık Erişim2021Scopus SJRQ2The effect of nurses' compassion on burnout: A cross-sectional study
Kaplan Serin, Emine; Özdemir, Ahmet; Işik, Kevser
Purpose: This study was carried out to determine the effect of nurses' compassion on burnout. Design and Methods: This cross-sectional descriptive study was conducted with 177 nurses. An introductory information form, the compassion scale and the Maslach burnout inventory were used as the data collection tools. Frequency, percentage, t test, analysis of variance, Kruskal-Wallis, correlation, and regression were used in the analysis of the data. Findings: The majority of the participants were determined to be female, married and university graduates. It was determined that there was a significant negative relationship between the nurses' sense of compassion and burnout levels, and burnout decreased as compassion increased. Practical Implication: Burnout and compassion fatigue may lead to inadequate care for the patient. This situation will negatively influence nurses' care quality.
AtıfScopus13WoS10OpenAlex14İncele - MakaleYalnız künye2021Scopus SJRQ2Infrared drying of dill leaves: Drying characteristics, temperature distributions, performance analyses and colour changes
Tezcan, Derya; Sabancı, Serdal; Cevik, Mutlu; Cokgezme, Omer Faruk; Icier, Filiz
Thin-layer drying behaviour of dill leaves samples under three different infrared radiation power intensities was investigated. Diffusion Approach was found to be the best model that describes the drying behaviour of dill leaves. Effective diffusivity values were 6.97 × 10−9, 6.84 × 10−9 and 8.96 × 10−9 m2/s for power intensities of 1790, 1970 and 2070 W/m2, respectively. According to the first and second law efficiencies, the infrared drying system was more efficient at higher power intensities (p < 0.05). However, the total colour change was maximum at the highest power intensity. For the investigated infrared drying conditions, 1970 W/m2 was recommended as the best-infrared power intensity applied for drying of dill leaves by taking into account both performance analyses and quality changes.
AtıfScopus40WoS34OpenAlex44İncele - MakaleAçık Erişim2021Scopus SJRQ2Intercultural awareness, communication, and empathy skills in nurses and midwives working in provinces with mass migration
Gümüşsoy, Süreyya; Dal, Nursel Alp; Beydağ, Kerime Derya; Toker, Eylem
Purpose: The study was to evaluate the intercultural awareness, communication, and empathy skills of midwives and nurses (n = 479). Design and Methods: The descriptive study data were collected using the Communication-Skills-Scale (CSS), the Basic-Empathy-Scale (BES), and the Intercultural-Awareness-Scale (IAS). Findings: The total average scores of the CSS, BES, and IAS were found to be 100.07 ± 13.03, 70.70 ± 13.99, and 83.51 ± 14.24, respectively. There was a statistically significant difference between age, education, position, experience and the BES and IAS; gender, providing care for Syrian patients and the CSS and BES; marital status and the BES (P %3C.05). Practice Implications: Nurses and midwives have important responsibilities in terms of protecting and improving the health of migrant women.
AtıfScopus7WoS6OpenAlex9İncele - MakaleAçık Erişim2021Scopus SJRQ1Attitudes of Married Muslim Women Regarding Family Planning Methods During the COVID-19 Pandemic in Western Turkey
Dal, Nursel Alp; Beydağ, Kerime Derya
COVID-19 had negative effects upon family planning. Women cannot visit healthcare facilities because of a fear of curfew-related sanctions or exposure to COVID-19. It is seen that religious beliefs are influential especially in terms of family planning method preference and having abortions. This study was conducted to determine the attitudes of married Muslim women regarding family planning methods during the COVID-19 pandemic period. The descriptive and cross-sectional study was conducted with 611 married Muslim women who presented to the family planning outpatient clinic of a public hospital in Western Turkey between 1 September 2020 and 1 March 2021. The mean Family Planning Attitude Scale score of the women was found to be 137.53 ± 27.11. It was observed that, as the mean age of the women increased, their family planning attitudes were more positive, and as their number of pregnancies, abortions and living children increased, their attitudes were more negative (p < 0.05). Women do not want to get pregnant during the pandemic process. This is because the effects of COVID-19 on both themselves and the baby to be born are not known, which worries women. Therefore, in order to transform positive attitudes regarding family planning into behavior, it is recommended to provide effective training and consultancy services during the pandemic period.
AtıfScopus5WoS4OpenAlex11İncele - MakaleAçık Erişim2021Scopus SJRQ2Towards the circular economy: Analysis of barriers to implementation of Turkey’s zero waste management using the fuzzy DEMATEL method
Ayçin, Ejder; Kayapinar Kaya, Sema
Zero waste has an important position in the circular economy model in terms of manufacturing recyclable products instead of products to be consumed quickly, reducing the amount of waste, developing and implementing recycling/reuse technologies, and thus ensuring resource efficiency. A zero-waste strategy is one of the basic steps to achieve the goal of the circular economy. The number of studies conducted on Turkey’s zero waste management strategies referring to the circular economy is quite limited. To fill this gap in the literature, this study aims to identify the potential barriers which have an important role in zero waste management practices in Turkey. Through a broad literature review and expert opinions, 12 key barriers for zero waste implementation in Turkey have been defined in view of circular economy principles. Then, fuzzy DEMATEL methodology is employed to examine which is the most influential barrier affecting zero waste management success and to identify the interdependence of these barriers. The results indicate that uncertainty of the goals and tactics relevant to the circular economy and lack of financial and economic aid are key causal barriers that affect Turkey’s zero waste management.
AtıfScopus65WoS49OpenAlex85İncele - MakaleAçık Erişim2021Scopus SJRQ1Teachers' views related the middle school curriculum for distance education during the COVID-19 pandemic
Aslan, Seda Akti; Turgut, Yigit Emrah; Aslan, Alper
This qualitative study aims to examine teachers’ opinions concerning the middle school curricula that have been in use for years, in order to determine its suitability for distance education during the COVID-19 pandemic. The participants consisted of eighteen middle school teachers from different subject areas in Turkey. A maximum variation sampling method was employed for participant selection. The data was collected through semi-structured interviews. Due to the pandemic, the interviews were conducted using video conferencing applications. The data was analyzed through content analysis. According to the findings, the teachers report that while they are effective in achieving cognitive objectives, they have difficulties in achieving affective and psychomotor objectives. In addition, the teachers do not prefer to design their own materials, rather they mainly benefit from ready-to-use materials during emergency distance education. The teachers also reveal that direct instruction and questioning were the teaching methods and techniques they preferred in online courses and that they were unable to adapt other methods and techniques to distance education, which resulted in students experiencing teacher-centered activities. Moreover, the teachers complain about students not attending the online courses on time or even at all, their disinterest, a lack of instant feedback, limited communication with students, and insufficient course lengths. Another critical finding was that the teachers only use homework, end-of-unit quizzes, and participation to online courses as measurement and evaluation tools and agree that they are unable to administer reliable and valid evaluation tools. The limitations of the study and implications for future research are later discussed.
AtıfScopus18WoS16OpenAlex40İncele - MakaleYalnız künye2021Scopus SJRQ1Relationship of knowledge about and attitudes towards violence with recognition of violence against women among health staff in pre-hospital emergency medical services
Gümüşsoy, Süreyya; Dönmez, Sevgül; Ekşi, Ali; Dal, Nursel Alp
Background: Domestic violence, specifically, violence against women, is prevalent in all segments of society regardless of social class, ethnicity, culture or country. In other words, domestic violence is a global concern. Aim: The study aims to investigate the relationship between the attitude and knowledge of the health staff in pre-hospital emergency medical services about violence against women and their recognition of such form of violence. Methods: This descriptive study was conducted on 1023 paramedics and emergency medicine technicians who work in the pre-hospital emergency health setting and are members of the Paramedic and Pre-hospital Emergency Medicine Association. The Attitudes towards Violence against Women Scale (ATVAWS) and Health Staff's Recognition of Signs of Violence against Women Scale (HPRSVAWS) were used for data collection. Results: The mean scores for the ATVAWS and HPRSVAWS were 46.68 ± 6.92 and 20.31 ± 3.23, respectively. Of the participants, 48.5% had been subjected to violence, 43.93% had been subjected to violence perpetrated by their mothers, 41.53% had been exposed to physical violence and 4.2% remain exposed to domestic violence. Participants who had been exposed and those who remain exposed to domestic violence produced high scores in ATVAWS, which indicates an improvement in the traditional approach (less opposing view) to violence. High scores in the ATVAWS for (a) those who were exposed to violence in their workplaces, (b) who had never attended to actual or suspected cases of violence against women in their professional life, (c) who had attended to seven or more cases of violence against women, (d) who were less competent in physically examining actual or suspected cases of violence and (e) who had not been trained on violence against women, which indicates an increase in the traditional approach to violence. Conclusion: The study found that health staff in emergency health stations better recognised the signs of violence against women as their attitudes towards violence were less similar to the traditional approach. That is, they mostly held non-violent views. The characteristics, attitudes, perceptions and values of health professionals were considered important factors in addressing violence.
AtıfScopus7WoS4OpenAlex10İncele - MakaleAçık Erişim2021Scopus SJRQ2Fabrication of porous-Ti6Al4V alloy by using hot pressing technique and Mg space holder for hard-tissue biomedical applications
Aslan, N.; Aksakal, B.; Findik, F.
Porous-Ti6Al4V (P-Ti6Al4V) alloys were produced using the hot pressing and spacer methods for hard tissue biomedical applications and in particular, the effects of porosity on the mechanical and morphological properties of the structures were investigated. P-Ti6Al4V structures having the homogeneously distributed porosities at 41.08, 52.37 and 64.10% were fabricated by adding 40, 50 and 60% spherical magnesium (Mg) powder with 350 μm particle sizes in average as spacers and evaporating magnesium via the atmosphere-controlled sintering. The obtained porous structures were characterized by SEM, XRD and EDS. Furthermore, the strength and elastic modulus were evaluated by performing compression tests. Elastic modulus and densities were found to be 40–171 MPa, 2–5 GPa and 1.59–2.61, respectively and these values have been shown to decrease with an increase in porosity. The achieved density and mechanical property values, in particular, elastic modulus are close to human bone and within acceptable ranges for with biomedical application purposes. In addition, it was also found out from the analysis of produced P-Ti6Al4V that macropores were responsible for mechanical anisotropy contributed to formation of homogeneous and inter-connected open pores. [Figure not available: see fulltext.]
AtıfScopus40WoS37OpenAlex39İncele - MakaleAçık Erişim2021Scopus SJRQ4Presence of Neospora caninum DNA of Wild Birds from Turkey; [Türkiye’deki Vahşi Kuşlarda Neospora caninum DNA’sının Varlığı]
Karakavuk, Muhammet; Can, Hüseyin; Aldemir, Duygu; Döndüren, Ömer; Karakavuk, Tuğba; Karakavuk, Emrah; Özdemir, Hüseyin Gökhan; Muz, Mustafa Necati; Gürüz, Adnan Yüksel; Döşkaya, Mert
Objective: Neospora caninum is a protozoon parasite that has a worldwide distribution and mainly causes abortion in cattle and current serological evidence shows that the disease may be also zoonotic. Wild birds play a role as a reservoir of the disease in nature. The study aimed to determine the prensence of N. caninum in wild birds. Methods: In this study, the presence of neosporosis in wild birds (n=55) including 22 different species found in the western side of Turkey, was investigated by polymerase chain reaction (PCR). In addition, PCR positive samples were confirmed by sequencing, BLAST, and phylogenetic analysis using MEGA7. Results: Obtained results showed that the presence of N. caninum DNA was 5.45% (3/55) in brain-heart homogenates wild birds. The bird species which were found positive for N. caninum were little owl (Athene noctua), common buzzard (Buteo buteo), and little tern (Sternula albifrons). According to phylogenetic analysis and BLAST, all samples were compatible with reference N. caninum isolates. Conclusion: To the best of authors’ knowledge, this is the first study detecting N. caninum in little tern. In future studies, it may be interesting to investigate the prevalence of N. caninum in other wild animals to elucidate the transmission properties.
AtıfScopus3OpenAlex3İncele - MakaleAçık Erişim2021Scopus SJRQ2Protective Effect of Lutein/Zeaxanthin Isomers in Traumatic Brain Injury in Mice
Gunal, Mehmet Yalcin; Sakul, Ayse Arzu; Caglayan, Ahmet Burak; Erten, Fusun; Kursun, Oznur Ece Durmaz; Kilic, Ertugrul; Sahin, Kazim
Previous studies revealed that oxidative stress and inflammation are the main contributors to secondary injury after traumatic brain injury (TBI). In an earlier study, we reported that lutein/zeaxanthin isomers (L/Zi) exert antioxidative and anti-inflammatory effects by activating the nuclear factor-kappa B (NF-κB) and nuclear factor-erythroid 2-related factor 2 (Nrf2) pathways. However, its precise role and underlying mechanisms were largely unknown after TBI. This study was conducted to investigate the potential mechanism of L/Zi isomers in a TBI model induced by a cold injury model in mice. To investigate the effects of L/Zi, male C57BL/6j mice-induced brain injury using the cold trauma model was allocated into two groups (n = 7): (i) TBI + vehicle group and (ii) TBI + L/Zi group (20 mg/kg BW). Brain samples were collected 24 h later for analyses. L/Zi given immediately after the injury decreased infarct volume and blood–brain barrier (BBB) permeability; L/Zi treatment also significantly reduced proinflammatory cytokines, including interleukin1 beta (IL-1β), interleukin 6 (IL-6), and NF-κB levels and increased growth-associated protein 43 (GAP-43), neural cell adhesion molecule (NCAM), brain-derived neurotrophic factor (BDNF), and Nrf2 levels compared with vehicle control. These data suggest that L/Zi improves mitochondrial function in TBI models, possibly decreasing inflammation and activating the Nrf2 pathway.
AtıfScopus39OpenAlex40İncele - MakaleYalnız künye2021Scopus SJRQ2Chrysin protects against testicular toxicity caused by lead acetate in rats with its antioxidant, anti-inflammatory, and antiapoptotic properties
Ileriturk, Mustafa; Benzer, Fulya; Aksu, Emrah Hicazi; Yildirim, Serkan; Kandemir, Fatih Mehmet; Dogan, Tuba; Dortbudak, Muhammet Bahaeddin; Genc, Aydin
In the present study, the protective effects of chrysin (CHR) against testicular damage caused by lead acetate (PbAc) were examined. In this way, 30 min after rats were given 25 and 50 mg/kg/b.w CHR orally for seven consecutive days, 30 mg/kg/b.w PbAc was administered orally. In biochemical analysis of testicular tissue, it was found that PbAc-reduced antioxidant parameters [glutathione peroxidase (GPx), glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT)], while it increased lipid peroxidation, inflammatory markers [nuclear factor kappa-B (NF-κB), cyclooxygenase-2 (COX-2), prostaglandin E2 (PGE-2), and inducible nitric oxide synthase (iNOS)], and 8-hydroxy-2′-deoxyguanosine (8-OHdG). In the immunohistochemical examination, it was determined that PbAc increased the expression of tumor necrosis factor-α (TNF-α) and caspase-3. Accordingly, PbAc was found to cause a decrease in sperm motility and an increase in the percentage of dead sperm. However, it has been observed that CHR relieves oxidative stress due to its antioxidant properties, thus protecting against inflammation and apoptosis. It also allowed the CHR sperm parameters to return to control group levels. The results revealed that CHR could be a natural substance to be used in Pb-induced testicular toxicity. Practical applications: Lead (Pb) is an important environmental contaminant heavy metal. Pb is believed to reduce fertility in men. Oxidative stress plays a significant role in the damage caused by Pb to testicular tissue. CHR is an antioxidant substance that occurs naturally in various plants and has various pharmacological properties. In the present study, it was investigated whether CHR has a protective effect against testicular toxicity induced by PbAc. The results revealed that in rats, CHR protects the testicular tissue from PbAc toxicity by showing antioxidant, anti-inflammatory and anti-apoptotic effects, thus bringing sperm parameters closer to normal.
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