Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Zengin, Gokhan(26)
- Erten, Fusun(20)
- Orhan, Cemal(17)
- Sahin, Kazim(17)
- Gul, Muhammet(15)
- Benzer, Fulya(12)
- Kocabaş, Mehmet(12)
- Aglar, Erdal(11)
- Serdar, Osman(11)
- Akkurt, Nevzat(10)
- Topal, Murat(10)
- Yeşiltepe, Akgün(10)
- Yucesan, Melih(10)
- Danabas, Durali(9)
- Er, Besir(9)
- Kutlu, Banu(9)
- Mahomoodally, Mohamad Fawzi(9)
- Uba, Abdullahi Ibrahim(9)
- Yildirim, Ozal(9)
- Öbek, Erdal(9)
- Acharya, U. Rajendra(8)
- Alp Dal, Nursel(8)
- Cakilcioglu, Ugur(8)
- Kandemir, Fatih Mehmet(8)
- Yildirim, Nuran Cikcikoglu(8)
- Arslan Topal, E. Işıl(7)
- Baloglu, Ulas Baran(7)
- Ozbey, Ulku(7)
- Sahin, Nurhan(7)
- Talo, Muhammed(7)
- Ates, Mehmet(6)
- Attar, Rukset(6)
- Dal, Nursel Alp(6)
- Gümüşsoy, Süreyya(6)
- Gürarslan Baş, Nazan(6)
- Ince, Muharrem(6)
- Kaplan Serin, Emine(6)
- Kutluyer, Filiz(6)
- Ozturk, Burhan(6)
- Aksu, Onder(5)
Yayınlar
- MakaleAçık Erişim2018Scopus SJRQ1The investigation of the shelf life at 2 ± 1 °C of Luciobarbus esocinus fillets packaged with films prepared with the addition of different essential oils and chitosan
Karaton Kuzgun, Nermin; Gürel İnanlı, Ayşe
In this study, the chemical, microbiological and sensory changes during storage at 2 ± 1 °C of Luciobarbus esocinus fillets coated with edible films prepared with chitosan incorporation of thyme, clove, rosemary essential oils were examined. To create the experimental samples, a total of six groups of L. esocinus fillets coated with different edible films (normal, vacuum-packed, chitosan, chitosan with added thyme oil, chitosan with added clove oil, and chitosan with added rosemary) were used. The food composition of the fillets and experimental samples were determined after they had been coated with edible films. The results of analysis showed that, the preservation period of fresh fillets ended on day 12th, that of vacuum-packed fillets on day 15th, that of fillets coated with chitosan incorporation of rosemary on day 27th, that of fillets coated with chitosan incorporation of thyme and chitosan incorporation of cloves on day 30th. In comparison with the control group, fish spoilage was significantly delayed in samples coated with chitosan incorporation of thyme and chitosan incorporation of cloves (p < 0.05). The lowest bacterial growth, values of PV, TBA and TVB-N were obtained in fish samples coated with thyme + chitosan and cloves + chitosan. In terms of the general acceptability of the fish, as determined by qualified panelists, it was determined that the highest score was given to the experimental group to which essential oil of clove had been applied.
AtıfScopus16WoS12OpenAlex17
İncele - MakaleAçık Erişim2017Assessment of Crystal Morphology on Uptake, Particle Dissolution, and Toxicity of Nanoscale Titanium Dioxide on Artemia salina
Johnson, M; Ates, M; Arslan, Z; Farah, I; Bogatu, C
AtıfOpenAlex38İncele - MakaleYalnız künye2017Scopus SJRQ1A food waste utilization study for removing lead(II) from drinks
Ince, Olcay Kaplan; Ince, Muharrem; Yonten, Vahap; Goksu, Ali
This is the first study about removal of lead (Pb(II)) from energy drinks. In this paper, food waste, namely eggshell (hydroxyapatite) utilization, was used to remove Pb(II) from mineral water and energy drinks. Mineral water and energy drinks were chosen for removal of lead since the latter is severely hazardous to human health even in small amounts. Response Surface Methodology (RSM) was performed to optimize the application process by practice of the quadratic model united with the Central Composite Design (CCD) and quadratic combined program was utilized to study the most effective parameters on aforementioned liquids. Through the application of variance analysis (ANOVA) factors critical to removing of lead were identified for each experimental design response. Maximum adsorption capacity of eggshell was achieved as 923 mg g(-1) for Pb(II). The obtained optimum conditions were applied to drinks. Results showed that used adsorbent was quite effective in removing Pb(II) from drinks. (C) 2016 Elsevier Ltd. All rights reserved.
AtıfWoS27OpenAlex28İncele - MakaleYalnız künye2017Scopus SJRQ3Synthesis and characterization of Bioglass-based bone grafts with Gelatine substitution for biomedical applications
Aksakal, B.; Demirel, M.
Background: Syntesizing alternative bone graft materials are important in biomedical applications. Their morphology, mechanical properties and cell viability plays an important role in tissue engineering. OBJECTIVE: Bioglass (B) based bone grafts with Gelatin (G) substitution were syntesized via the sol-gel method and were compared with various Gelatin and Bioglass concentrations (wt%). METHODS: Syntesized bone grafts were characterized by Scanning Electron Microscopy (SEM) and X-ray diffraction (XRD) to show the structural and morphological changes of the fabricated B-based bone grafts. RESULTS: It was demonstrated that the concentration of pore size increased with increasing amounts of Gelatin in wt%. The biograft-B40G20 produced the highest flexture strength and hardness. Increasing the pore size caused a decrease in hardness and flexture stress of B-based biografts. CONCLUSIONS: Cell viability tests were conducted on the fabricated biografts and it was shown that the cell viability increased in fabricated B-based bone grafts.
AtıfScopus1WoS1OpenAlex1İncele - MakaleYalnız künye2017Scopus SJRQ2Effect of Cobalt on Sperm Motility in an Endangered Trout Species, Salmo coruhensis
Kocabaş, Mehmet; Kutluyer, Filiz
Experiments were designed to examine the in vitro effect of cobalt on sperm motility of the endangered trout species (Salmo coruhensis). Sperm samples were diluted in an immobilizing solution, and activated in a motility-activation solution that was supplemented with cobalt at concentrations of 1, 10, 100 and 1000 mg/L. The percentage of motile sperm and duration of motility were determined. Cobalt concentrations of 1–100 mg/L had a positive effect on the percentage of motile sperm and duration of motility compared to the control group, while a concentration of 1000 mg/L resulted in decreases in these parameters (p < 0.05). The percentages of motile sperm at cobalt concentrations of 0, 1, 10, 100 and 1000 mg/L were 83.33% ± 0.25%, 88.33% ± 0.34%, 89.00% ± 0.57%, 90.00% ± 0.87% and 42.50% ± 0.45%, respectively; and the time durations over which the sperm remained motile were 72.00 ± 0.63, 74.83 ± 0.28, 77.40 ± 0.47, 81.14 ± 0.78, and 50.25 ± 0.67 s, respectively. This study has shown that sperm motility and duration were significantly enhanced (p < 0.05) at cobalt concentrations of 1, 10 and 100 mg/L, relative to controls, and significantly decreased at 1000 mg/L.
AtıfScopus11WoS9OpenAlex14İncele - MakaleAçık Erişim2017Scopus SJRQ1Change of mechanical properties of powder recyclate reinforced polyolefin based on gamma radiation
Kismet, Yilmaz
In this study, the changes observed in the mechanical properties of standard test specimens that were produced with powder coating reinforced polyolefin (polyethylene and polypropylene) due to gamma radiation were examined. Matrix material of these specimens included low density polyethylene and polypropylene and 5%, 10%, 20%, 30%, 40% and 50% electrostatic powder coating waste by weight, and the samples were exposed to 44 kGry gamma-radiation for twenty four hours. Mechanical tests applied to the specimens after radiation demonstrated that the physical bonding mechanism between matrix material and filler material was reinforced. In the mechanical tests, tensile strength, three-point bending strength, and Izod impact strength of the samples were investigated and the results were compared to the results obtained in the mechanical tests when they were not radiated. Thus, the effects of gamma radiation on the mechanical properties of the filler material, and the electrostatic powder coating reinforced polyethylene and polypropylene were determined. Furthermore, section images of the radiated samples were taken with a scanning electron microscope and compared to the section images of irradiated samples to observe the physical bonding mechanism.
AtıfScopus12WoS12OpenAlex15İncele - MakaleYalnız künye2017Scopus SJRQ1A novel overlapped nuclei splitting algorithm for histopathological images
Serin, Faruk; Erturkler, Metin; Gul, Mehmet
Background and objective Nuclei segmentation is a common process for quantitative analysis of histopathological images. However, this process generally results in overlapping of nuclei due to the nature of images, the sample preparation and staining, and image acquisition processes as well as insufficiency of 2D histopathological images to represent 3D characteristics of tissues. We present a novel algorithm to split overlapped nuclei. Methods The histopathological images are initially segmented by K-Means segmentation algorithm. Then, nuclei cluster are converted to binary image. The overlapping is detected by applying threshold area value to nuclei in the binary image. The splitting algorithm is applied to the overlapped nuclei. In first stage of splitting, circles are drawn on overlapped nuclei. The radius of the circles is calculated by using circle area formula, and each pixel's coordinates of overlapped nuclei are selected as center coordinates for each circle. The pixels in the circle that contains maximum number of intersected pixels in both the circle and the overlapped nuclei are removed from the overlapped nuclei, and the filled circle labeled as a nucleus. Results The algorithm has been tested on histopathological images of healthy and damaged kidney tissues and compared with the results provided by an expert and three related studies. The results demonstrated that the proposed splitting algorithm can segment the overlapping nuclei with accuracy of 84%. Conclusions The study presents a novel algorithm splitting the overlapped nuclei in histopathological images and provides more accurate cell counting in histopathological analysis. Furthermore, the proposed splitting algorithm has the potential to be used in different fields to split any overlapped circular patterns.
AtıfScopus6WoS7OpenAlex7İncele - MakaleYalnız künye2017Scopus SJRQ2Optimizing electrocoagulation process using experimental design for COD removal from unsanitary landfill leachate
Ogedey, Aysenur; Tanyol, Mehtap
Leachate is the most difficult wastewater to be treated due to its complex content and high pollution release. For this reason, since it is not possible to be treated with a single process, a pre-treatment is needed. In the present study, a batch electrocoagulation reactor containing aluminum and iron electrodes was used to reduce chemical oxygen demand (COD) from landfill leachate (Tunceli, Turkey). Optimization of COD elimination was carried out with response surface methodology to describe the interaction effect of four main process independent parameters (current density, inter-electrode distance, pH and time of electrolysis). The optimum current density, inter-electrode distance, pH and time of electrolysis for maximum COD removal (43%) were found to be 19.42 mA/m2, 0.96 cm, 7.23 and 67.64 min, respectively. The results shown that the electrocoagulation process can be used as a pre-treatment step for leachate.
AtıfScopus15WoS16İncele - Derleme MakaleYayıncıda açık erişim2017Scopus SJRQ3Regulation of signaling pathways by tanshinones in different cancers
Lin, X.; Qureshi, M.Z.; Romero, M.A.; Khalid, S.; Aras, A.; Ozbey, U.; Farooqi, A.A.
Past several years have witnessed dramatic leaps in our understanding of rewiring of gene expression at the translation level during cancer developmentthat provides linchpin support to the transformed phenotype. Most recent and ground-breaking developments in the field of molecular oncology aredriven by an explosion in technological advancements and have started to reveal previously unimagined regulatory mechanisms and how they intricately co-ordinate to modulate cancer progression, loss of apoptosis and development of resistance against different therapeutics. However, the insights gained from work in this natural product research have far-reaching impact because of rapidly increasing repertoire of medicinally and biologically efficient phytochemicals. How Tanshinones mediate targeting of JAK-STAT, ER stress associated signaling cascade,PI3K/AKT/mTOR pathway,autophagy, TRAIL pathway and microRNAs are being discovered and will prove to be helpful in getting a step closer to personalized medicine.
AtıfScopus12OpenAlex12İncele - MakaleYalnız künye2017Scopus SJRQ1Heavy metal and arsenic concentrations in rainbow trout (Oncorhynchus mykiss) farmed in a dam reservoir on the Firat (Euphrates) River: Risk-based consumption advisories
Varol, Memet; Kaya, Gülderen Kurt; Alp, Alper
The concentrations of ten metals in rainbow trout (Oncorhynchus mykiss) farmed in the Karakaya Dam Reservoir (Turkey) on the Firat River were determined. The metal concentrations in rainbow trout did not exceed the maximum permissible levels. Biomagnification factors (BMF) of ten metals were < 1, indicating that these metals were not biomagnified. The estimated daily intake (EDI) of each metal was much lower than the respective tolerable daily intake (TDI). The target hazard quotient (THQ) for individual metal and total THQ for combined metals were lower than 1, indicating no health risk for consumers due to the intake of either individual metal or combined metals. The cancer risk (CR) value for toxic inorganic As was below 10–6, indicating no carcinogenic risk. According to the calculated maximum allowable consumption rates (CRmm), an adult may safely consume 28 meals of rainbow trout from the dam reservoir per month with no adverse carcinogenic and non-carcinogenic health effects. According to these results, the consumption of rainbow trout farmed in this dam reservoir is completely safe for human health.
AtıfScopus193WoS169OpenAlex201İncele - MakaleAçık Erişim2017Scopus SJRQ3Effects of role-playing scenarios on the self-efficacy of students in resisting against substance addiction: A pilot study
Karatay, Gülnaz; Baş, Nazan Gürarslan
During the first phases of adolescent development, young people have little self-efficacy and resistance against substance use. The aim of this study was to demonstrate the effectiveness of role-playing scenarios on the self-efficacy of students in resisting substance use. A pre test and post test study design was used with a single group. The study was carried out with 245 secondary school students. The scenario-based training, developed by the researchers, was presented by the school counselors once a week for 4 weeks. For this purpose, a booklet of scenarios was prepared for the teachers. The role-playing scenarios were intended to improve adolescents’ abilities to say "no" to substance offers, to prevent them from becoming addicted to certain substances, and to call for help if needed. The data of the study were collected using the Personal Information Form and the Self-Efficacy for Adolescences Protecting Substance Abuse Scale. The obtained data were assessed using percentages, chi-square, t test, and F test in the SPSS software. Results showed that, after the training, the mean score in the Self-Efficacy for Adolescences Protecting Substance Abuse Scale increased significantly (103.20 ± 20.00) compared with before the training (92.11 ± 17.08) (P <.05). Short-term outcomes of the class-based scenario training were observed to be effective in the development of students’ self-efficacy to resist the temptations of substance use.
AtıfScopus13WoS9OpenAlex23İncele - MakaleAçık Erişim2017Scopus SJRQ2Calibration-free extraction of constitutive parameters of magnetically coupled anisotropic metamaterials using waveguide measurements
Hasar, U.C.; Buldu, G.; Bute, M.; Muratoglu, A.
A calibration-free method for extraction of electromagnetic properties of magnetically coupled anisotropic biaxial metamaterial (MM) slabs from waveguide measurements is proposed. It relies on three measurement steps (thru, empty line, and the same line arbitrarily loaded by the MM slab) to extract electromagnetic properties. It is evaluated against another calibration-dependent method for retrieval of electromagnetic properties of a MM slab constructed by C-shaped resonators. From evaluation analysis, we note that our method, as compared to the calibration-dependent method, not only accurately extracts electromagnetic properties without requiring the use of expensive calibration standards but also is reference-invariant.
AtıfScopus10OpenAlex11İncele - MakaleAçık Erişim2017Scopus SJRQ2Antioxidant Response in Duckweed After Exposure to Secondary Effluent from Municipal Wastewater Treatment Plant, Elazığ, Turkey
Tatar, Sule Yuksel; Obek, Erdal; Cikcikoglu Yildirim, Nuran
The aim of this study is to evaluate the effects of the effluent of Elazig Municipality Wastewater Treatment Plant on the oxidative defense capacity of aquatic plants (Lemna minor L. and Lemna gibba L.). For this purpose, malondialdehyde (MDA), glutathione (GSH), oxidized glutathione (GSSG), vitamin A (retinol), vitamin E (α-tocopherol), and vitamin C (Ascorbic acid) levels were determined by the HPLC (high performance liquid chromatography) in the control groups and the groups adapting to reactors fed with discharge water. The depletion of vitamins (A, E, and C), decrease of GSH/GSSG ratio, and increase of MDA that reflect a precarious state of the cell in L. minor L. and L. gibba L. were observed after exposure to wastewater. It can be suggested that the selected biomarkers are useful in understanding the biochemical mechanisms of the secondary effluents from wastewater treatment plant in L. minor L. and L. gibba L. as early warning indicators.
AtıfScopus6WoS8İncele - MakaleYalnız künye2017Scopus SJRQ2Phase-ambiguity-free and accurate permittivity determination from waveguide measurements
Hasar, U.C.; Buldu, G.
A microwave method has been proposed for accurate and unique extraction of relative complex permittivity (ϵr) of dielectric materials from 2π phase-ambiguity-free amplitude-only two-port and one-port scattering parameter measurements. Improved accuracy has been shown by the applied uncertainty analysis. For the validation of our method, ϵr of low-loss and lossy samples was extracted.
AtıfScopus2WoS2OpenAlex2İncele - Derleme MakaleAçık Erişim2017Scopus SJRQ3Regulation of signal transduction cascades by Pterostilbenes in different cancers: Is it a death knell for oncogenic pathways
Butt, Ghazala; Attar, Rukset; Tabassum, Sobia; Aras, Aliye; Qadir, Muhammad Imran; Ozbey, Ulku; Alaaeddine, Nada; Ozcelik, Beraat; Farooqi, Ammad Ahmad
Interdisciplinary research has revolutionized the field of medicine and we have witnessed exponential increase in the high-impact research in past few decades. However, the road to this burgeoning research field is obstacle-ridden because of intratumor heterogeneity, loss of apoptosis and dysregulation of spatio-temporally controlled signaling pathways. Ground-breaking findings obtained through genetic, genomic and proteomic studies have considerably improved our concepts related to the complexity of protein network and excitingly, discovery of miRNAs has added another layer of intricacy to quantitatively regulated gene networks. In this review, we chronicle the milestone achievements and discuss how Pterostilbenes effectively regulated different cellular pathways. We have provided detailed mechanistic insights related to regulation of JAK-STAT signaling, Notch pathway, Wnt mediated intracellular signaling by pterostilbene. Underlying mechanisms about regulation of PI3K/AKT and MAPK pathways by pterostilbene in different cancers. Regulation of Metastasis-associated protein 1 (MTA1) proteins and Human telomerase reverse transcriptase (hTERT) in cancer cells by pterostilbene. Pterostilbene has also been reported to modulate the expression of various oncogenic and tumor suppressor microRNAs in cancer cells. Better and sharper comprehension of the concepts associated with the modes of action of pterostilbene in different cancers will be useful in identification of cancers which can be efficiently targeted by pterostilbene.
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