Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Baskonus, Haci Mehmet(25)
- Sulaiman, Tukur Abdulkadir(22)
- Bulut, Hasan(21)
- Agoujil, S(8)
- Atangana, A(8)
- Baskonus, HM(8)
- Benzer, Fulya(8)
- Bulut, H(8)
- Cattani, C(8)
- Hammouch, Z(8)
- Mekkaoui, T(8)
- Gul, Muhammet(7)
- Can, Erkan(6)
- Celik, Erkan(6)
- Kutluyer, Filiz(6)
- Onat, Onur(6)
- Serdar, Osman(6)
- Demir, Yakup(5)
- Erişir, Mine(5)
- Kutlu, Banu(5)
- Yildirim, Ozal(5)
- Yıldırım, Özal(5)
- Aksu, Önder(4)
- Akyuz, Emre(4)
- Erguven, Gokhan Onder(4)
- Gürarslan Baş, Nazan(4)
- Karaaslan, Nagihan M.(4)
- Karatay, Gülnaz(4)
- Kizak, Volkan(4)
- Kocabaş, Mehmet(4)
- Çimen, Okay(4)
- Acharya, U. Rajendra(3)
- Aktürk, Tolga(3)
- Alataş, Mevlüt(3)
- Baloglu, Ulas Baran(3)
- Baskonus, H.M.(3)
- Bulut, H.(3)
- Cattani, Carlo(3)
- Celik, E.(3)
- Firat, Erhan(3)
Yayınlar
- MakaleYalnız künye2018Scopus SJRQ3Synthesis and Characterization of Hydroxyapatite/TiO2 Coatings on the β-Type Titanium Alloys with Different Sintering Parameters using Sol-Gel Method
Dikici, B.; Niinomi, M.; Topuz, M.; Say, Y.; Aksakal, B.; Yilmazer, H.; Nakai, M.
In this study, hydroxyapatite (HA) based composite films were successfully syntheses on the β-type Ti29Nb13Ta4.6Zr (TNTZ). The solutionized TNTZ substrates coated with HA and HA/Titania (TiO2) bioactive composite coatings by sol-gel method under various sintering parameters related to sintering temperatures and heating ramp rates. Microstructural observations of the coatings revealed that apatite was formed on the substrates. The hardness values of the coatings increase with increasing both the sintering temperature and the TiO2 concentration in the coatings layer. However, it was found that the heating ramp rate of the sintering was not affecting the hardness values so much. Also, the hardness values of the HA/TiO2 composite coatings at all sintering temperatures were higher than only HA coated TNTZ samples due to the existence TiO2 phases in the HA matrix. Results indicating that the doping of HA with TiO2, improve the physical consistency between the coating layer and the substrates and provide a better inter-particle bonding due to the existence TiO2 phases in the HA.
AtıfScopus42OpenAlex43
İncele - MakaleAçık Erişim2018Scopus SJRQ1An optimisation support for the design of hybrid production lines including assembly and disassembly tasks
Mete, Süleyman; Çil, Zeynel Abidin; Özceylan, Eren; Ağpak, Kürşad; Battaïa, Olga
The optimisation problems related to the assignment of tasks to workstations in assembly and disassembly lines have been largely discussed in the literature. They are known, respectively, as Assembly Line Balancing and Disassembly Line Balancing Problems. In this study, both types of task performed on the identical product are integrated in a common hybrid production system. Therefore, the logistic process is simplified and disassembly tasks can supply easier the assembly tasks with the required components. The considered production system has the layout of two parallel lines with common workstations. The product flow is conventional in the assembly line and reverse in the disassembly line. The paper provides a new mathematical model for designing such a hybrid system and an approximate approach based on ant colony optimisation for solving large-scale instances. The solution method is tested in a case study. The obtained results are compared with the solution provided by the design of two independent lines. The analysis of the results highlights the potential benefits of the hybrid production system.
AtıfScopus53OpenAlex51İncele - MakaleAçık Erişim2018The antiiflammatory effect of Ginkgo biloba in lipopolysaccharide-induced rat sepsis model
Ilhan, Nevin; Susam, Solmaz; Ak, Tuba Parlak; Baykalir, Burcu Gul
Background: Sepsis is characterized dysregulated inflammatory response and is the leading cause of organ failure or injury and death in critical care units. Ginkgo biloba extract 761 (EGb 761) is characterized by antioxidant activity. There is no clear data in the functional role of EGb 761 that inhibiting of proinflammatory cytokines exist in sepsis. The purpose of this study was to investigate the antiinflammatory effect of EGb 761 on the levels of vascular endothelial growth factor (VEGF), matrix metalloproteinase-9 (MMP-9) and inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS) induced rat sepsis model. Methods: The animals were randomly divided into the following six groups: the control, LPS, flunixin meglumine (FM), EGb 761, LPS + FM and LPS + EGb 761 groups. Enzyme-linked immunosorbent assay (ELISA) analysis was applied to measure serum levels of VEGF, MMP-9, and iNOS. Results: Serum iNOs (p < 0.05), VEGF (p < 0.01) and MMP-9 (p < 0.05) levels were significantly higher in the sepsis group. Treatment with EGb 761 decreased serum iNOs levels (p < 0.01), VEGF and MMP-9 levels decreased significantly (p < 0.05). Also, treatment with FM decreased iNOs (p < 0.01), VEGF and MMP-9 levels significantly (p < 0.05). Conclusions: It is suggested that sepsis may lead to increase serum iNOs, MMP-9, and VEGF levels and treatment of EGb 761 may have a potential antiinflammatory effect against LPS-induced sepsis.
AtıfOpenAlex1İncele - MakaleAçık Erişim2018Scopus SJRQ4Comparing transperineal ultrasonography and vaginal examination for discomfort in labor follow-up
Saridoǧan, Erdinç; Alp Dal, Nursel; Özdemir, Çaǧdaş; Şimşek, Erkan; Aǧlamiş, Özgür; Özgü, Burçin
Objective: This study aimed at knowing the difference between the pain scores of intrapartum transperineal ultrasonography and vaginal examination. Material and Methods: A total of 146 pregnant women who were in cephalic presentation and active phase of labor at term with low risk were evaluated prospectively by transperineal ultrasonography (TU) and vaginal examination (VE). The active phase of labor was accepted to be 5-6 cm of cervical dilatation, >60% of cervical effacement, and >250 Montevideo units or at least three regular uterine contractions in ten minutes in cardiotocography. Descriptive characteristics and pain scores (using a visual analogue scale) were assessed. Results: The mean value of transperineal ultrasonography pain scores was 5.48±1.39 (minimum 2 and maximum 8) and the mean value of vaginal examination pain scores was 7.12±1.28 (minimum 4 to maximum 10) (p<0.001). The mean transperineal pain scores of nulliparous and multiparous women were 5.93±1.36 and 5.15±1.32, respectively (p<0.001). The mean vaginal examination pain scores of nulliparous women and multiparous women were 7.54±1.23 and 6.82±1.24, respectively (p<0.001). Conclusion: The use of ultrasonography in the follow-up of labor seems to be more acceptable and a less painful method.
- MakaleYayıncıda açık erişim2018Scopus SJRQ2Application of Computational Intelligence Methods for the Automated Identification of Paper-Ink Samples Based on LIBS
Rzecki, Krzysztof; Sośnicki, Tomasz; Baran, Mateusz; Niedźwiecki, Michał; Król, Małgorzata; Łojewski, Tomasz; Acharya, U. Rajendra; Yildirim, Özal; Pławiak, Paweł
Laser-induced breakdown spectroscopy (LIBS) is an important analysis technique with applications in many industrial branches and fields of scientific research. Nowadays, the advantages of LIBS are impaired by the main drawback in the interpretation of obtained spectra and identification of observed spectral lines. This procedure is highly time-consuming since it is essentially based on the comparison of lines present in the spectrum with the literature database. This paper proposes the use of various computational intelligence methods to develop a reliable and fast classification of quasi-destructively acquired LIBS spectra into a set of predefined classes. We focus on a specific problem of classification of paper-ink samples into 30 separate, predefined classes. For each of 30 classes (10 pens of each of 5 ink types combined with 10 sheets of 5 paper types plus empty pages), 100 LIBS spectra are collected. Four variants of preprocessing, seven classifiers (decision trees, random forest, k-nearest neighbor, support vector machine, probabilistic neural network, multi-layer perceptron, and generalized regression neural network), 5-fold stratified cross-validation, and a test on an independent set (for methods evaluation) scenarios are employed. Our developed system yielded an accuracy of 99.08%, obtained using the random forest classifier. Our results clearly demonstrates that machine learning methods can be used to identify the paper-ink samples based on LIBS reliably at a faster rate.
AtıfScopus39
İncele - MakaleYalnız künye2018Scopus SJRQ3Anesthetic efficacy of cymbopogon citratus essential oil as a herbal agent in two ornamental fish species
Kizak, Volkan; Can, Erkan; Can, Şafak Seyhaneyildiz; Özçiçek, Esin
The efficacy of Cymbopogon citratus essential oil (CcEO) as a herbal anesthetic agent was evaluated for two ornamental fish species, Sciaenochromis fryeri and Labidochromis caeruleus. Fish were exposed to various essential oil concentrations and the lowest effective concentrations were determined according to deep anesthesia (AD<3 min) and full recovery (RF<10 min) times. CcEO showed anesthetic traits and induced AD in S. fryeri and L. caeruleus. The lowest effective concentrations was 200 µl/L for S. fryeri (AD; RF → 122 ± 1.8 s; 638 ± 8.9 s) and 200 µl/L for L. caeruleus (AD; RF → 139 ± 6.9 s; 625 ± 11.1 s). At concentration of 25 µl/L C. citratus essential oil did not induce AD in both of ornamental fish species. No significant differences were found between fish species in terms of induction and recovery times for same concentrations excluding AD time of 200 µl/L concentration. Although the fastest AD were obtained by 300 µl/L, recovery times were prolonged and fish did not full recover in 20 min. Induction and recovery times for CcEO were significantly dependent on concentrations and negative relationships were recorded between AD and RF. Neither mortality nor adverse effects were observed on two fish species. As a result, CcEO showed anesthetic properties for S. fryeri and L. caeruleus.
AtıfScopus8İncele - MakaleYalnız künye2018Scopus SJRQ2The using of Gammarus pulex as a biomonitor in ecological risk assessment of secondary effluent from municipal wastewater treatment plant in Tunceli, Turkey
Tatar, Sule; Cikcikoglu Yildirim, Nuran; Serdar, Osman; Yildirim, Numan; Ogedey, Aysenur
The objectives of this research are the assessment of secondary effluents (SEs) quality by evaluating chemical parameters and biomarkers. For this purpose, MDA and GSH levels were determined by spectrofotometer. SOD, CAT, and GPX activities were determined by using ELISA kit in the groups of control and the groups exposed to SE. The level of MDA and the activities of SOD in Gammarus pulex vary depending on the exposure time. GSH levels and GSH-PX activities increased in G. pulex exposed to the effluent compared to the control during 24 h and 96 h. CAT activities were in SE group were found lower than the control in G. pulex during 24 h and 96 h. Current experimental results show that SOD, CAT, GPX activities, and GSH and MDA levels in G. pulex are sensitive and appropriate responses for assess the effects of anthropogenic contaminants on the aquatic ecosystems, particularly effluent complex mixtures.
AtıfScopus19WoS19OpenAlex22İncele - Kitap BölümüYalnız künye2018Scopus SJRQ4Nonlinear dynamical model for DNA
Baskonus, Haci Mehmet; Cattani, Carlo; Agarwal, P; Dragomir, SS; Jleli, M; Samet, B
This chapter deals with a nonlinear dynamical system arising in the analysis of the double-chain model in deoxyribonucleic acid (DNA). Bernoulli sub-equation function method and modified exp (-Ω(ξ))-expansion function method to obtain some novel dynamical structures to the nonlinear dynamical system are used. We construct some new exponential, hyperbolic and complex periodic wave solutions to this model. Under some suitable values of parameters, we plot the 2D and 3D graphics of the solutions obtained in this study. All the solutions found in this study satisfy the nonlinear dynamical system. Moreover, these solutions can be used to explain some new significant physical meanings of the nonlinear dynamical model for DNA.
AtıfScopus10WoS9OpenAlex8İncele - MakaleYalnız künye2018Scopus SJRQ1Application of Artificial Neural Networks to the prediction of out-of-plane response of infill walls subjected to shake table
Onat, Onur; Gul, Muhammet
The main purpose of this paper is to predict missing absolute out-of-plane displacements and failure limits of infill walls by artificial neural network (ANN) models. For this purpose, two shake table experiments are performed. These experiments are conducted on a 1:1 scale one-bay one-story reinforced concrete frame (RCF) with an infill wall. One of the experimental models is composed of unreinforced brick model (URB) enclosures with an RCF and other is composed of an infill wall with bed joint reinforcement (BJR) enclosures with an RCF. An artificial earthquake load is applied with four acceleration levels to the URB model and with five acceleration levels to the BJR model. After a certain acceleration level, the accelerometers are detached from the wall to prevent damage to them. The removal of these instruments results in missing data. The missing absolute maximum out-of-plane displacements are predicted with ANN models. Failure of the infill wall in the out-of-plane direction is also predicted at the 0.79g acceleration level. An accuracy of 99% is obtained for the available data. In addition, a benchmark analysis with multiple regressionis performed. This study validates that the ANN-based procedure estimates missing experimental data more accurately than multiple regression models.
AtıfScopus33WoS29OpenAlex14İncele - MakaleAçık Erişim2018Scopus SJRQ3Morphological, anatomical and cytological investigations on three taxa of Centaurea L. (Asteraceae) from Turkey
Tasar, Neslihan; Doğan, Gülden; Kiran, Yaşar; Oliur Rahman, M.; Çakilcioğlu, Uğur
Morphological, anatomical and cytological features of three Turkish taxa of Centaurea L., viz. C. polypodiifolia Boiss. var. polypodiifolia, C. urvillei DC. subsp. urvillei and C. urvillei subsp. armata Wagenitz were investigated. Stem anatomy revealed the presence of a thick cuticle layer outside the stem, and epidermis with dense hairs was observed in the lower part. Investigation on leaf anatomy showed that different types of hairs on the outside of the leaf were very intense. Palisade parenchyma was observed below the upper and lower epidermis. In Centaurea polypodiifolia var. polypodiifolia, chromosome number was found to be 2n=16, while in C. urvillei subsp. urvillei and C. urvillei subsp. armata 2n=20. Total karyotype length of C. polypodiifolia var. polypodiifolia, C. urvillei subsp. urvillei and C. urvillei subsp. armata was 22.9 μm, 37.84 μm and 40.01 μm, respectively. Among the investigated taxa the karyotype asymmetry index was found lowest in C. urvillei subsp. armata. Satellite was detected in C. urvillei subsp. urvillei and subsp. armata, while it was absent in C. polypodiifolia Boiss. var. polypodiifolia.
AtıfScopus15WoS17OpenAlex9İncele - MakaleAçık Erişim2018Scopus SJRQ3Extracellular Synthesis and Characterization of Gold Nanoparticles Using Mycobacterium sp. BRS2A-AR2 Isolated from the Aerial Roots of the Ghanaian Mangrove Plant, Rhizophora racemosa
Camas, Mustafa; Sazak Camas, Anil; Kyeremeh, Kwaku
Through the use of genomes that have undergone millions of years of evolution, marine Actinobacteria are known to have adapted to rapidly changing environmental pressures. The result is a huge chemical and biological diversity among marine Actinobacteria. It is gradually becoming a known fact that, marine Actinobacteria have the capability to produce nanoparticles which have reasonable sizes and structures with possible applications in biotechnology and pharmacology. Mycobacterium sp. BRS2A-AR2 was isolated from the aerial roots of the mangrove plant Rhizophora racemosa. The Mycobacterium was demonstrated for the first time ever to produce AuNPs with sizes that range between 5 and 55 nm. The highest level absorbance of the biosynthesized AuNPs was typical for actinobacterial strains (2.881 at 545 nm). The polydispersity index was measured as 0.207 in DLS and the zeta potential was negatively charged (− 28.3 mV). Significant vibration stretches were seen at 3314, 2358, 1635 and 667 cm−1 in FT-IR spectra. This demonstrated the possible use of small aliphatic compounds containing –COOH, –OH, –Cl and –NH2 functional groups in the stabilization of the AuNPs. The effect of the biosynthesized AuNPs on HUVEC and HeLA cell lines was measured at 48 h. IC50 values were determined at 3500 µg/ml concentration for HUVEC and HeLA cell lines at 45.25 and 53.41% respectively.
AtıfScopus66WoS35OpenAlex58İncele - MakaleYalnız künye2018Scopus SJRQ3Assessment and ICP-MS determination of toxic metal content (Cd, Cr, Ni, and Pb) in Ibrkish chicken meat for use as bioindicator for human health
Karaaslan, Nagihan M.; Yaman, Mehmet
The aim of this study was to determine the toxic metal concentrations in chicken meat consumed by the Turkish population and to establish health risk assessment. The concentrations of cadmium (Cd), chromium (Cr), nickel (Ni), and lead (Pb) in chicken meat produced by seven different suppliers were determined using inductively coupled plasma mass spectrometry (ICP- MS). The Cd concentrations in all samples were found to be lower than the maximum allowable concentration (MAC) of 50 Hg kg-1. The Cr and Ni concentrations in all samples were lower than 700 and 450 μg kg-1, respectively, with the exception of Cr in the samples from one producer and of Ni from two other producers. The Pb concentrations (max. 413 μg kg-1) in the samples from three producers were found to be higher than the MAC of 100 μg kg-1. Although the concentrations of lead in some samples exceed the limits set by the authorities, risk of developing cancer over a human lifetime was found to be not significant (between 3 to 16 per 1,000,000 persons).
AtıfScopus8İncele - MakaleAçık Erişim2018Scopus SJRQ3The chemical and biochemical oxygen demand reduction by armillaria tabescens in malathion supplemented culture medium
Yildirim, N.; Erguven, G.O.; Adar, E.
The extensive use of pesticides for controlling insects has been widely used in agricultural activities. However, the indiscriminate use of the pesticides has inflicted serious harmful problems to humans in the ecosystem. Our study aims to evaluating the capacity of Armillaria tabescens to remove the chemical oxygen demand (COD) and biochemical oxygen demand (BOD5) at different concentration of malathion insecticide (50, 100 and 150 ppm) under agitated (130 rpm) submerged culture conditions at 27 °C after 8 and 15 days. According to our results, A. tabescens has achieved COD reduction as 52.39, 27.24, and 38.30% at concentration of 50, 100 and 150 ppm respectively on 15 days. The BOD5 reduction rates were found as 78.2, 74.76 and 81.26% at 50, 100 and 150 ppm concentration respectively at the end of the 15th days. At the end of this time period, the dried biomass of A. tabescens was weighted and we have suggested that malathion in medium reduced the biomass production compared the control group (Sabouraud dextrose broth + A. tabescens). Our experiments have focused that; A. tabescens could be an alternative and useful fungus for bioremediation of wastewater containing malathion insecticide.
AtıfScopus3WoS3OpenAlex4İncele - MakaleAçık Erişim2018Scopus SJRQ1Topic recommendation for authors as a link prediction problem
Aslan, Serpil; Kaya, Mehmet
Recently, link prediction studies on large-scale and complex networks have particularly become the focus of interest for researchers in various scientific fields. Many complex networks created from the real-world data contain bipartite structure by nature. Bipartite networks are a kind of complex networks that represent the interactions between the different node groups. Almost all of the previous studies on link prediction in bipartite networks focus on using the properties of projection networks to predict the relations between the node pairs. In this study, a novel similarity-based link prediction method based on strengthening weighted projection is proposed to predict the potential links between the authors and the topics in the large-scale bipartite academic information network created from the real-world data. Since information loss occurs when bipartite networks are converted to unimodal networks, it should be noted that when making a link prediction in this paper, both the bipartite network and the information on strengthening unimodal network obtained from the bipartite network are used. To evaluate the proposed method, a bipartite network was first created from a real dataset consisting of authors and their work. Then the method was tested on this network. Experimental results demonstrate that it is possible to obtain faster and more accurate link prediction results by the proposed method.
AtıfScopus35WoS25OpenAlex34İncele - MakaleAçık Erişim2018Scopus SJRQ3Traditional honey production and bee flora of Espiye, Turkey
Karaköse, Mustafa; Polat, Ridvan; Rahman, M. Oliur; Çakilcioglu, Ugur
This paper presents potential honey bee plants in Espiye (Giresun) which can be considered as a guide for beekeepers and researchers. A total of 149 taxa belonging to 125 genara and 48 families were recorded as pollen and nectary sources for honey bee colonies at Espiye (Giresun) region. Among the recorded taxa 58 were Phanerophytes, 57 taxa Hemicryptophytes, 19 taxa Therophytes, 13 taxa Cryptophytes and 2 taxa Chamaephytes. Updated nomenclature along with the families, local names, life form, flowering period and ecological status have been furnished under 94 herbs, 28 shrubs and 27 trees.
AtıfScopus10WoS13OpenAlex18İncele - MakaleAçık Erişim2018Scopus SJRQ3Anesthetic efficiency of 2-phenoxyethanol on broodstock of salmo munzuricus, a new trout species originating from munzur stream; [Munzur akarsuyu orijinli yeni bir alabalık türü olan salmo munzuricus’un anaç bireyleri üzerinde 2-fenoksietanol’ün anestezik etkinliği]
Can, Erkan; Başusta, Asiye; Karataş, Bilal
Salmo munzuricus is a newly-named species of trout that spreads through rivers flowing along the Munzur Valley National Park. The efficacy of anaesthetic 2-phenoxyethanol was evaluated in indigenous brown trout in the present study. Fish were divided into three weight classes: 100-200 g (W1), 200-400 g (W2) and 400-600 g (W3) and they were exposed to four concentrations of anaesthetic (0.2, 0.3, 0.4 and 0.5 mL L-1). The lowest induction time was identified in the group W3 while the highest one was in the group W1. The lowest recovery time occurred after 73.2±3.83 sec in the group W3 and the highest one was 136±31.46 sec in the group W1. The recovery times were increased with increasing the concentration of 2-phenoxyethanol in the group W1. However, recovery times in the groups W2 and W3 were significantly longer than observed in W1, generally. Besides, it was indicated that fish size affected induction times and recovery times. As a result of the present study, the most appropriate concentrations were determined as 0.4 mL L-1 at weights of 100-400 g while 0.5 mL L-1 at weights of 400-600 g for 2-phenoxyethanol in Salmo munzuricus broodstock.
AtıfScopus4WoS4OpenAlex1İncele - MakaleYalnız künye2018Scopus SJRQ1Comparative evaluation of toxicological effects and recovery patterns in zebrafish (Danio rerio) after exposure to phosalone-based and cypermethrin-based pesticides
Korkmaz, Volkan; Güngördü, Abbas; Ozmen, Murat
This study evaluated the toxic effects and recovery patterns in zebrafish (Danio rerio) after exposure to phosalone-based (PBP) and cypermethrin-based (CBP) pesticides. Initially, the 96 h LC50 values of the pesticides were calculated as being 5.35 µg of active ingredient (AI) L−1 for CBP and 217 µg AI L−1 for PBP based on measured concentrations. Accordingly, experimental groups were exposed to three sublethal concentrations of pesticides for 96 h, separately, and then zebrafish were transferred to pesticide-free conditions for 10 and 20 days recovery periods. Biochemical markers were assessed including carboxylesterase (CaE), acetylcholinesterase (AChE), glutathione S-transferase (GST), lactate dehydrogenase, glutathione peroxidase, catalase, alanine and aspartate aminotransferase (ALT, AST) activities after the exposure and recovery periods. Also, the pesticide concentrations in test water were quantified by high-performance liquid chromatography (HPLC) analysis. Our results showed that AChE and CaE activities were significantly inhibited and GST was induced by both pesticides after 96 h exposure. For PBP exposure, the decreases for GST induction and CaE inhibition showed a partial recovery in pesticide-free conditions. However, the decreases in AChE activity for CBP exposure and insufficient increases in same enzyme activity for PBP exposure after 20 days in pesticide-free conditions indicated that the projected recovery period was not enough to the recovery of AChE activities and for the improvement of fish health.
AtıfScopus56WoS50OpenAlex59İncele - MakaleAçık Erişim2018Scopus SJRQ1A practical application of human reliability assessment for operating procedures of the emergency fire pump at ship
Akyuz, Emre; Celik, Erkan; Celik, Metin
This paper aims to conduct a practical application for human reliability assessment during operating procedures of an emergency fire pump on-board ship. A systematic human error prediction is performed for designated tasks during operational procedures of the emergency fire pump since human error can be regarded as one of the major factors contributing accidents at sea. Hence, human reliability performance is evaluated to enhance fire safety management in operational level on-board ship. In the paper, marine-specific error producing conditions are adopted under fuzzy sets environment. To enhance consistency of research and minimise subjectivity during expert's judgement stage, the paper is supported with a dominance factor which is used to adjust the impact level of expert's judgments in the aggregation stage of the methodology. The outcomes of the paper provide valuable contributions to the safety managers and technical superintends to monitor fire safety management and crew reliability performance.
AtıfScopus44WoS38OpenAlex42İncele - MakaleAçık Erişim2018Scopus SJRQ3Maslinic acid as an effective anticancer agent
Lin, Xiukun; Ozbey, Ulku; Uteuliyev, Yerzhan Sabitaliyevich; Attar, Rukset; Ozcelik, Beraat; Zhang, Yuanyan; Guo, Mingyue; Liu, Minghua; Alhewairini, Saleh S.; Farooqi, Ammad Ahmad
Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid) is a naturally occurring pentacyclic triterpenic compound. Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. In this review we will focus on chemopreventive properties of Maslinic acid against different cancers. Seemingly, available data is limited and we have yet to unravel how Maslinic acid therapeutically targeted oncogenic cell signal transduction cascades in different cancers. Moreover, there are visible knowledge gaps about the ability of Maslinic acid to modulate oncogenic and tumor suppressor microRNAs in various cancers.
AtıfScopus20OpenAlex17İncele - MakaleAçık Erişim2018Scopus SJRQ3Karyological investigation on seven centaurea L. (Asteraceae) Taxa from Turkey
Tasar, Neslihan; Dogan, Gulden; Kiran, Yasar
The somatic chromosome numbers and karyotypes were examined in seven species of genus Centaurea L. distributed in Turkey. The chromosome numbers were determined as 2n=2x=16 in C. behen L. and C. solstitialis L.; 2n=2x=18 in C. cynarocephala Wagenitz and C. agregata Fisch. & Mey. ex DC. ssp. agregata; 2n=2x=20 in C. iberica Trev. ex Sprengel; 2n=2x=26 in C. balsamita Lam.; 2n=4x=36 in C. virgata Lam. All of the chromosomes had centromeres at median point (M), median region (m), and submedian region (sm). Satellite chromosomes (sat-chromosomes) were observed only in C. virgata. The findings for each of the analyzed taxa are compared each other and with the results of previous studies.
AtıfScopus5WoS3OpenAlex1İncele
