Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Zengin, Gokhan(26)
- Erten, Fusun(20)
- Orhan, Cemal(17)
- Sahin, Kazim(17)
- Gul, Muhammet(15)
- Benzer, Fulya(12)
- Kocabaş, Mehmet(12)
- Aglar, Erdal(11)
- Serdar, Osman(11)
- Akkurt, Nevzat(10)
- Topal, Murat(10)
- Yeşiltepe, Akgün(10)
- Yucesan, Melih(10)
- Danabas, Durali(9)
- Er, Besir(9)
- Kutlu, Banu(9)
- Mahomoodally, Mohamad Fawzi(9)
- Uba, Abdullahi Ibrahim(9)
- Yildirim, Ozal(9)
- Öbek, Erdal(9)
- Acharya, U. Rajendra(8)
- Alp Dal, Nursel(8)
- Cakilcioglu, Ugur(8)
- Kandemir, Fatih Mehmet(8)
- Yildirim, Nuran Cikcikoglu(8)
- Arslan Topal, E. Işıl(7)
- Baloglu, Ulas Baran(7)
- Ozbey, Ulku(7)
- Sahin, Nurhan(7)
- Talo, Muhammed(7)
- Ates, Mehmet(6)
- Attar, Rukset(6)
- Dal, Nursel Alp(6)
- Gümüşsoy, Süreyya(6)
- Gürarslan Baş, Nazan(6)
- Ince, Muharrem(6)
- Kaplan Serin, Emine(6)
- Kutluyer, Filiz(6)
- Ozturk, Burhan(6)
- Aksu, Onder(5)
Yayınlar
- MakaleAçık Erişim2026Scopus SJRQ1Multi-Response Kinetic Modeling of the Maillard Reaction in Milk During Heating at Ultra-High-Temperature Range
Hamzalıoǧlu, Aytül; Aktaǧ, Işıl; Gökmen, Vural
This study developed first a comprehensive multiresponse kinetic model to elucidate the mechanism of the Maillard reaction in milk during ultrahigh-temperature treatment. The model incorporates the alterations in precursors (sugars, amino acids), intermediates (α-dicarbonyl and Amadori compounds) and products (N-ε-carboxymethyllysine, N-ε-carboxyethyllysine) that occur in milk during heating between 110 and 140 °C. Kinetically important reactions steps were identified by multiresponse kinetic modeling. Results indicated that N-ε-carboxymethyllysine and N-ε-carboxyethyllysine were formed predominantly by the oxidation of lactulosyllysine. Among the intermediates, the formation of 1-deoxyglucosone and glucosone, and methylglyoxal from 1-deoxyglucosone and glyoxal from glucosone, were determined to be the kinetically important steps. The rate-limiting step was identified as lactulosyllysine formation, while methylglyoxal generation occurred most rapidly across all heating temperatures. In this study, the multiresponse kinetic modeling approach was applied to milk, offering a comprehensive understanding of the critical pathways leading to the formation of α-dicarbonyl compounds and advanced glycation end-products.
- MakaleAçık Erişim2026Scopus SJRQ1Dietary exposure and health risk assessment of fumonisins through the consumption of maize and maize-based gluten-free products in individuals with celiac disease
Tuyben, Eylem Ezgi; Sevim, Sumeyra; Macit, Arife; Kizil, Mevlude
Introduction: Individuals with celiac disease (CD) must adhere to a gluten-free diet (GFD) and are therefore at high risk of fumonisin exposure due to their high consumption of maize and maize-based products. This study aimed to determine the concentrations of fumonisins (FB1, FB2, and FB3) in packaged gluten-free (GF) maize and maizebased products sold in Turkey and to assess dietary exposure and health risks in adults with CD using a probabilistic approach. Methods: Fumonisin concentrations of 51 GF products were analyzed by Enzyme-Linked Immonosorbent Assay (ELISA) and daily food consumption data were collected from 67 individuals with CD through a food frequency questionnaire. Exposure was estimated using Estimated Daily Intake (EDI) values and probabilistic risk assessment with Monte Carlo simulation. Results: The highest fumonisins concentrations were detected in the pasta/rice/bulgur group, while the flour/starch group was the food group contributed most to total fumonisins exposure due to higher consumption. Although the average EDI values were below the Tolerable Daily Intake (TDI; 1 μg/kg bw/day) set by European Food Safety Authority’s (EFSA) and Provisional maximum tolerable daily intakes (PMTDI; 2 μg/kg bw/day) established by Joint Expert Committee on Food Additives’s (JECFA) values, individuals at the 95th percentile approached 132.88–167.89% of the PMTDI value in the flour/starch group and 79.00–82.38% in the pasta/rice/bulgur group. Discussion: These findings highlight the need for continuous monitoring and stricter regulatory oversight and dietary guidance to protect vulnerable populations.
- MakaleAçık Erişim2026Scopus SJRQ2Tribological Performance of SPS-Fabricated Cu-HEA/Gr Composites Under Current-Carrying Sliding Contact
Ozkaya, Serdar; Çelebi, Müslim; Yanar, Harun; Karabacak, Abdullah Hasan; Çelik, Ertuğrul; Güler, Onur; Coskun, Abdulkadir; Sekban, Dursun Murat
Cu-based hybrid composites reinforced with AlCrFeCuNi high-entropy alloy (HEA) particles and graphene were successfully fabricated by spark plasma sintering (SPS) to investigate the combined effects of microstructure, mechanical properties, and tribological performance under electrical current. Microstructural observations revealed a dense and homogeneous distribution of HEA particles within the Cu matrix, while the addition of 2.0 wt.% graphene promoted noticeable grain refinement due to its grain boundary pinning effect. Although graphene addition provided beneficial effects in terms of grain refinement and electrical conductivity, it also increased the porosity from 2.49% to 5.08%. Consequently, the beneficial contribution of graphene to mechanical strengthening was substantially offset by the adverse effect of increased porosity, resulting in only a marginal increase in hardness from 127 HB to 129 HB. The addition of 2.0 wt.% graphene led to a pronounced change in the tribological behavior of the composites. The Cu–HEA exhibited relatively stable friction behavior but experienced a higher wear rate under all test conditions. In comparison, the Cu–HEA–2.0 Gr composite demonstrated a lower coefficient of friction and wear rate at 0–10 A, which is consistent with the possible formation of a graphene-rich lubricating surface layer. A clear transition occurred at 30 A, where the coefficient of friction and wear rate began to increase, while at 50 A, further increases in both parameters were observed, suggesting progressive disruption of the proposed protective surface layer under the investigated current-carrying sliding conditions.
- MakaleAçık Erişim2026Scopus SJRQ1EBA-Net: A hybrid EfficientNetB3-BiLSTM-Attention model for species-level diatom classification
Balo Utku, Esen Damla; Kutlu, Banu; Utku, Anil
Species identification in diatoms is important for assessing water bodies, determining environmental quality, and analyzing biodiversity. Nonetheless, diatom classification has proven difficult due to intra-class variation, interclass similarity, and data imbalance in microscopic images. In this regard, we propose a new deep learning approach for species-level diatom classification. Various deep learning models, including traditional convolutional neural networks or CNNs (ResNet50, DenseNet121), state-of-the-art CNNs (EfficientNetB3, Xception, MobileNetV3), transformer-based architectures (ViT-B16, Swin-Tiny), and our proposed EBA-Net (EfficientNetB3-BiLSTM-Attention Network), were extensively compared under identical experimental settings. The EBA-Net integrates the advantages of convolutional feature extraction, sequence modeling, and an attention mechanism to improve classification accuracy. It first uses the EfficientNetB3 model as the backbone network to obtain higher-level features, followed by a BiLSTM layer to capture dependencies among the extracted features. Then, it applies the attention mechanism to the BiLSTM output to highlight the most informative features. Experimental results showed that the proposed EBA-Net model outperforms other models considered in the study, yielding 95.8% accuracy and 85.1% macro F1-score. In addition, Top-3 (98.9%) and Top-5 (99.6%) accuracies confirmed the efficiency of the proposed model for classifying objects from visually similar classes. An analysis of the model's interpretability was conducted using Gradient-weighted Class Activation Mapping, showing that the proposed model's attention is concentrated on relevant morphological features of diatoms. To the best of our knowledge, the suggested approach achieves state-of-the-art accuracy on the data set of diatoms used.
- MakaleAçık Erişim2026Scopus SJRQ1Impact of Postharvest Oxalic Acid Treatments on Quality Properties and Biochemical Composition of Medlar (Mespilus germanica L.) Fruit
Çolak, Ayşen Melda; Gündoğdu, Özlem; Aglar, Erdal; Sezgin, Nevzat; Orman, Erdal; Gundogdu, Muttalip
This study was conducted to investigate the effects of oxalic acid (OA) applications at different concentrations on the quality traits and biochemical components of medlar (Mespilus germanica L.) fruit. Fruits harvested in Bolu province in 2024 were subjected to control (0) and 0.5, 1.0, and 1.5 mM OA applications and stored at 4°C and 90% ± 5% relative humidity for 45 days. Samples were taken from the fruits at certain intervals (0, 15, 30, and 45 days) and analyzed. Specifically, 1.0 and 1.5 mM OA applications significantly reduced fruit weight loss and decay rates. OA also inhibited increases in fruit respiration rate and pH and slowed the decline in total acidity, soluble solids content (SSC), vitamin C, phenolic compounds, and organic acids. Malic, citric, succinic, tartaric, and fumaric acids, vitamin C, and important phenolic compounds (chlorogenic acid, gallic acid, quercetin, catechin) were protected by OA applications, and this protection was most pronounced at 1.5 mM OA dose. The correlation analyses revealed significant relationships between quality parameters and biochemical contents. The weight loss and decay rate were negatively correlated with bioactive compounds such as gallic acid and ascorbic acid, indicating that quality deterioration progressed in parallel with the decrease in nutrient content. A strong positive correlation was found between titratable acidity and malic and citric acids. In principal component analysis (PCA), malic and citric acids were prominent in the early storage period, while weight loss, decay, and increased respiration became dominant in the late storage period. Phenolic compounds decreased significantly with storage time, and antioxidant capacity decreased. Heat map analysis visually supported the increase in spoilage parameters with the decrease in ascorbic acid and phenolic compounds. OA applications maintained the quality of medlar fruit and increased biochemical stability, extending postharvest life. 1.5 mM OA, in particular, stands out as an effective postharvest preservation method. These results demonstrate that OA offers significant potential for increasing the commercial value of perishable fruits like medlar and for developing preservation technologies.
AtıfScopus1OpenAlex1
İncele - MakaleAçık Erişim2026Scopus SJRQ1Optimization of scours downstream of conduit aerators
Arici, Erdinc; Tuna, M. Cihat; Aytac, Ayca; Acar, Ramazan; Tunc, Mustafa
Dams, wastewater treatment plants, and aquaculture areas often require aeration, making it crucial for hydraulic engineers to predict the physical properties of scour holes occurring on the downstream side of conduits. Conduit systems that provide high aeration performance necessitate multiple optimization studies to simultaneously maximize the scour parameters and the system’s physical properties. In this study, the physical parameters of conduit systems and downstream scour parameters were optimized using Artificial Neural Networks (ANN). The optimum system parameters were identified based on the experimental results through ANN-based optimization. Additionally, the real and optimal effects of the parameters on aeration performance and scour were determined. The results of the study demonstrated that ANN can be effectively used in studies aimed at optimizing the aeration performance and scour values of conduits. This study is the first to apply ANN for the simultaneous optimization of both aeration efficiency (Qa/Qw) and scour characteristics (dmax and δ) in a conduit-based hydraulic system. Previous studies have typically focused on either scour or aeration individually; this study integrates both through a multi-objective ANN model. The findings provide novel insights for the design and retrofitting of energy-dissipating conduit structures in high-head dam applications. Unlike traditional empirical or regression-based approaches, the ANN model captures complex, nonlinear relationships among multiple interacting hydraulic variables. It identified optimal parameter combinations — such as 70% gate opening, 1.30–1.50 m conduit length, and 9 mm air hole diameter — that improve both aeration and scour behavior. These outcomes offer direct applicability for real-world hydraulic system optimization.
AtıfOpenAlex1İncele - MakaleAçık Erişim2026Scopus SJRQ1Influence of apple pomace and asparaginase on acrylamide levels in cookies and behavior during simulated gastric digestion: risk assessment perspectives
Sevim, Sumeyra; Macit, Arife; Farıa, Miguel A.; Viegas, Olga; Cunha, Sara C.; Kizil, Mevlude; Ferreira, Isabel M.P.L.V.O.
Cookies are widely consumed baked products; however, their contribution to dietary acrylamide (ACR) intake raises increasing health concerns. This study investigated the effects of apple pomace addition and asparaginase treatment on ACR levels in cookies, the fate of ACR during simulated gastric digestion using the INFOGEST semi-dynamic model, and the associated health risks of ACR exposure from cookie consumption. Risk assessment was conducted for adults (18–65 years) and children (3–10 years) using Monte Carlo simulation. Three formulations were evaluated: a control cookie, a cookie in which wheat flour was partially replaced with apple pomace, and a cookie containing asparaginase. Cookies formulated with apple pomace contained significantly lower ACR levels than the control (132 ± 8 μg/kg vs. 215 ± 11 μg/kg; p < 0.05), although the reduction was less pronounced than in cookies containing asparaginase (65 ± 14 μg/kg). During gastric digestion, ACR exhibited formulation-dependent release kinetics. Nevertheless, the total ACR released at the end of digestion was similar for control and pomace cookies, likely due to additional ACR formation in the stomach, despite differences in release patterns throughout digestion. Margin of Exposure (MOE) values for children remained well below 10,000, indicating a potential carcinogenic risk, although reductions of up to 59% were observed for control and pomace cookies after digestion. Target Hazard Quotient (THQ) values showed a slight increase after digestion in both age groups but remained below 1, suggesting no concern for chronic toxicity. Control cookies indicated a potential carcinogenic risk for children (ILCR = 1.56 × 10−4), whereas pomace and asparaginase formulations reduced this risk (ILCR = 9.59 × 10−5 and 4.72 × 10−5, respectively). However, simulated gastric digestion increased ILCR values for both control and pomace cookies (2.24 × 10−4 and 2.33 × 10−4, respectively). These findings indicate that dietary exposure to ACR cannot be assessed solely based on its concentration in food, and that digestive kinetics should be incorporated into health risk assessment.
- MakaleAçık Erişim2026Scopus SJRQ2Radiation shielding performance of CeO2-reinforced ternary nanocomposites based on biodegradable polymers and waste-derived polystyrene
Pekdemir, Mustafa Ersin; Yilmaz, Demet; Selçuk Pekdemir, Sibel; Gülhan, Aleyna; Yalçin Kuzu, Serpil; Altun, Sedanur; Taşgin, Yahya
The development of sustainable polymer-based materials for radiation shielding has attracted increasing interest, particularly for lightweight and flexible applications. In this study, ternary nanocomposites based on poly (hydroxyalkanoate) (PHA), poly (ε-caprolactone) (PCL), and polystyrene (PS) were prepared and reinforced with cerium oxide (CeO2) nanoparticles (5–15 wt%) to enhance radiation shielding performance. Structural characterization confirmed the preservation of polymer chemical structures and the successful incorporation of crystalline CeO2, while SEM observations revealed a relatively homogeneous nanoparticle dispersion within the ternary matrix, particularly at intermediate filler loadings. Thermal analysis demonstrated enhanced thermal stability with increasing CeO2 content, as evidenced by an increase in residual mass from 0.42% for the neat blend to 11.21% for the nanocomposite containing 15 wt% CeO2, along with a shift of degradation onset temperatures toward higher values. Photon shielding performance was experimentally evaluated in the energy range of 13.37–59.54 keV. The incorporation of 15 wt% CeO2 increased the mass attenuation coefficient (MAC) from 1.277 to 12.366 cm2 g−1 at 13.37 keV, corresponding to an approximately ninefold enhancement, while significantly reducing the half-value layer (HVL) and mean free path (MFP). Neutron shielding analysis showed a slight decrease in thermal neutron attenuation due to hydrogen dilution within the polymer matrix, whereas fast neutron attenuation and neutron removal cross sections exhibited only minor variations; the fast neutron removal cross section increased modestly from 0.1014 to 0.1047 cm−1 with 15 wt% CeO2 addition. Overall, the results highlight clear structure–property–performance relationships in CeO2-reinforced PHA/PCL/PS nanocomposites, demonstrating their potential as lightweight radiation shielding materials for low energy protection with improved thermal stability and shielding efficiency.
AtıfScopus2OpenAlex1İncele - MakaleYalnız künye2026Scopus SJRQ1Feeding problems in Turkish children with down syndrome and parental quality of life: A cross-sectional study
Okyar, Ferit; Kemer, Duygu
Background Children with Down syndrome (DS) often have feeding problems, which may negatively affect the quality of life (QoL) of their parents. This study aimed to identify feeding problems in children with DS and to examine the relationship between these feeding problems and parental QoL. Methods This cross-sectional study included 105 parents of children aged 10–18 years with DS in Turkey. Data were collected through face-to-face interviews using the Screening Tool of Feeding Problems (STEP) and the SF-36 Health Survey (SF-36). Results This study indicated that the mean STEP scale scores were below the average level across all frequency × severity subscales. Parents' mean scores on the SF-36 QoL scale were above the reference mean (x̄ = 50.00) for the physical functioning, vitality, mental health, social functioning, pain, and general health perception subscales, whereas scores for the physical role limitation and emotional role limitation subscales were below the reference mean. In this study, a moderate negative correlation was found between STEP subscale scores and parents' mean SF-36 subscale scores ( p ≤ 0.05). Conclusions In this study, a significant negative correlation was found between the STEP subscale scores and the parents' mean SF-36 subscale scores. Implications to practice: Routine feeding assessments using the STEP scale should be conducted for children with DS, and nurse-led parent education programs addressing feeding problems should be implemented.
- MakaleAçık Erişim2026Scopus SJRQ1Pomological and Biochemical Characterization of Autochthonous Grape Varieties Grown in Türkiye
Karasu, Yakup; Dogan, Adnan; Aykut, Semih; Ozturk, Burhan; Aglar, Erdal
Grapevine (Vitis vinifera L.) is an important fruit crop with considerable morphological and biochemical diversity, and autochthonous genotypes represent valuable genetic resources for breeding and conservation programs. Many local varieties remain underexplored in terms of pomological and antioxidant traits. Eighteen indigenous grape genotypes collected from Muş province (Eastern Anatolia, Türkiye) were evaluated using morphological and biochemical parameters, including berry traits, phenolic composition, vitamin C, and antioxidant activity. Multivariate analyses including PCA, HCA, and Pearson correlation were performed to classify genotypes and determine trait relationships. The first two PCA components explained 51.9% of the total variation. Antioxidant-related traits mainly contributed to PC1, whereas berry size and anthocyanin content influenced PC2. HCA grouped the genotypes into distinct clusters according to antioxidant capacity and pomological characteristics. Correlation analysis showed significant positive relationships among antioxidant-related parameters. Berry size traits were positively correlated with each other, but negatively associated with seed number and skin thickness. The combined use of pomological, biochemical, and multivariate analyses proved useful for genotype classification. The identification of antioxidant-rich genotypes may support future breeding and conservation studies. The results highlight the importance of indigenous grape germplasm for sustainable viticulture.
- DüzeltmeYayıncıda açık erişim2026Scopus SJRQ1Correction: Comprehensive Biological and Chemical Evaluation of Two Seseli Species (S. gummiferum and S. transcaucasicum) (Antioxidants, (2021), 10, 10, (1510), 10.3390/antiox10101510)
Zengin, Gokhan; Stojković, Dejan; Mahomoodally, Mohamad Fawzi; Jugreet, Bibi Sharmeen; Paksoy, Mehmet Yavuz; Ivanov, Marija; Gašić, Uroš; Gallo, Monica; Montesano, Domenico
In the original publication [1], there was a mistake in Figure 1 as published. The figure, as published, did not include the appropriate statistical information. We have revised the figure accordingly, and the corrected version of “Figure 1” is presented below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
- MakaleAçık Erişim2026Scopus SJRQ1The Efficacy of Structured Exercise Program Versus Aerobic Exercise in Tension-Type Headache: A Randomised Clinical Trial
Ataş, Kübra; Mutlu, Ebru Kaya
Background: Despite the widespread use of exercise in managing tension-type headache, there remains a lack of research on the effectiveness of combined structured exercise programs. The aim of this study was to investigate the effects of a structured exercise program versus aerobic exercise of equal duration on tension-type headache (TTH). Methods: Fifty-four female participants aged between 18 and 55 years were randomised to receive a 12-week exercise program, conducted twice a week for 45 min per session. The Structured Exercise Group (SEG) participated in a combination of aerobic, strengthening, and stretching exercises, whereas the Aerobic Exercise Group (AEG) performed only aerobic exercises. The primary outcome measure was the Headache Impact Test (HIT-6), a quality-of-life questionnaire. Secondary outcome measures included headache intensity, disability level, pressure pain threshold, proprioception, muscle strength, cervical posture, exercise capacity, anxiety, and depression. Results: Both groups showed statistically significant improvements in quality of life, pain intensity, disability, anxiety, depression, exercise capacity, pressure pain threshold, and proprioception (p < 0.05). Between-group comparisons revealed that the SEG demonstrated significantly greater improvements in quality of life, pressure pain threshold, proprioception, muscle strength, and posture (p < 0.05), whereas the AEG showed superior gains in exercise capacity (p < 0.05). Conclusion: Both exercise programs appear similarly effective for self-reported outcomes. Based on clinical measurement results, we recommend incorporating strengthening and stretching exercises into the aerobic exercise program and extending the duration to 12 weeks for additional benefits. Significance Statement: This study highlights the clinical value of supervised, physiotherapist-led exercise and the integration of personalised, multi-component strategies in managing tension-type headache. While both structured and aerobic programs improved pain, activity, and participation, the structured approach provided additional benefits in pressure pain threshold, proprioception, muscle strength, and posture. Tailoring interventions to individual clinical needs and extending the duration beyond 8 weeks may further enhance outcomes.
- MakaleYalnız künye2025Scopus SJRQ2Green synthesis of environmentally friendly Ag/AgCl nanoparticles for use as solid phase extraction materials
Kurnaz Yetim, Nurdan; Hasanoğlu Özkan, Elvan; Aslan, Naim; Koç, Mümin Mehmet; Nartop, Dilek; Özcan, Cemile
Green synthesis is a prominent procedure used to easily and environmentally friendly fabricate nanostructures and nanoparticles (NPs), without complex instrumentation, intricate procedures, and harmful chemicals. This study investigated the green synthesis of silver NPs (AgNPs), with Aronia melanocarpa fruit extract as the reducing agent. Following synthesis optimization, AgNPs were characterized using a range of analytical techniques, including UV–Vis, XRD, SEM-EDX, BET, and TEM analyses. Based on the characterization results, an Ag/AgCl hybrid structure was formed. The Ag/AgCl NPs obtained were utilized as adsorbents to remove Cd(II) and Pb(II) heavy metals. The experimental factors that were optimized included pH (5.5), sample volume (5 mL), eluent type and concentration (2 M HNO3), adsorbent amount (5 mg), and extraction time (30 min). Under optimized conditions, the limits of detection were determined to be 9.6 and 4.8 µg/L for Pb(II) and Cd(II), respectively. These limits were established within a concentration range of 50–3,000 µg/L.
AtıfScopus3WoS3OpenAlex3İncele - Derleme MakaleYalnız künye2025Scopus SJRQ2Is sexual function impaired in patients with primary headaches? A systematic review of observational studies
Ataş, Kübra; Kaya Mutlu, Ebru
Introduction: Primary headaches, particularly migraine and tension-type headaches, as chronic and painful conditions, have a significant impact on individuals' health and overall quality of life, including aspects such as sexual health parameters. Objectives: The aim of this study was to review observational studies and to summarize the presence of sexual dysfunction in patients with primary headache and to discern whether it is more common in patients with primary headache than in healthy control subjects. Methods: Observational studies published between January 1, 2000, and May 21, 2023 were searched in Medline (PubMed), Web of Science, Scopus, and EBSCO. This review included 23 observational studies that evaluated sexual dysfunction with or without comparison with healthy control subjects. Results: As a result, the mean Female Sexual Function Index score, a score of <26.55 indicating sexual dysfunction, ranged from 19.25 ± 8.18 to 27.5 ± 7.5 in patients with primary headache. The prevalence of sexual dysfunction and erectile dysfunction was found to be between 10.7% and 93.75% in female patients and between 54.83% and 80% in male patients. Both migraineurs and tension-type headache sufferers had statistically significantly lower sexual function scores in females and lower erectile function scores in males compared with healthy control subjects. Conclusion: Sexual function is significantly affected in patients with primary headache, which is a chronic painful disorder. Therefore, it is very important to ask these patients about their sexual health and, if necessary, to seek support from a sexual health professional. Additionally, future studies may prioritize tension-type headaches and male patients due to the limited amount of research available on these subjects.
AtıfScopus1WoS1OpenAlex1İncele - MakaleAçık Erişim2025Scopus SJRQ2Maximizing performance in child footballers: chronotype and time of day study
Kaba, Ilknur; Engin Çelikel, Baha; Adanur, Oğuzhan; Yılmaz, Coşkun; Yonca Sezer, Süreyya; Tan, Çetin; Durhan, Tebessüm Ayyıldız; Özer, Uğur; Ceylan, Tülay
Background: A limited number of studies have investigated the effects of circadian rhythm-based running exercise interventions on physical fitness in child athletes. This study aimed to investigate the effects of an eight-week morning and evening running program on lower extremity strength, agility and respiratory function in 10–12-year-old male footballers. Methods: Participants visited the laboratory three times, with one-day intervals before and after the training program. The assessments included maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and the FEV1/FVC ratio. Additionally, agility and functional performance tests (FPTs) were conducted for both the dominant and non-dominant legs. Results: The findings indicated that morning running was more effective than evening running in enhancing respiratory function. Morning running also showed superior results in lower extremity strength tests, particularly in the single-leg (SL) and triple-leg (THD) crossover hop for distance tests (CHDs) and the 6-m timed-hop test (6 m THT). Furthermore, the agility performance of the morning running group was significantly better than that of the evening and control groups. Conclusion: Consequently, morning running interventions had a positive impact on key physical fitness parameters, including respiratory muscle strength, respiratory function, agility, and lower extremity strength in child footballers.
- MakaleAçık Erişim2025Scopus SJRQ3Establishing a link between the chemical composition and biological activities of Gladiolus italicus Mill. from the Turkish flora utilizing in vitro, in silico and network pharmacological methodologies
Zengin, Gokhan; Cetiz, Mehmet Veysi; Abul, Nurgul; Gulcin, Ilhami; Caprioli, Giovanni; Piatti, Diletta; Ricciutelli, Massimo; Koyuncu, Ismail; Yuksekdag, Ozgur; Bahşi, Muammer
Objectives: Five solvent extracts (n-hexane, ethyl acetate, ethanol, ethanol/water (70%), and water) of Gladiolus italicus Mill. from Turkey were evaluated for chemical and biological properties. Methods: Antioxidant activities, inhibitory properties against key enzymes involved in the etiology of chronic diseases were tested, as well as cytotoxic effects on different cell lines. Chemical characterization was also carried out to determine the most abundant compounds of each extract. Results: The highest total phenolic content (TPC) was observed in the water extract while highest TFC in ethanol/water extract. The most abundant compounds in the extracts were hyperoside (69041.06 mg kg−1), isoquercitrin (46239.49 mg kg−1), delphindin-3,5-diglucoside (42043.81 mg kg−1), myricetin (21486.61 mg kg−1), and kaempferol-3-glucoside (21199.76 mg kg−1). Molecular dynamic (MD) simulations confirmed the structural stability and dynamic conformational integrity of these complexes over a period of 100 ns. In network pharmacology, A total of 657 unique target genes were screened: 52 associated with programmed cell death-1 (PD-1), 85 with vascular endothelial growth factor receptor-2 (VEGFR2), and 130 with fibroblast growth factor receptor-2 (FGFR2), identifying crucial gene interactions for these proteins. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were conducted, revealing significant interactions and pathways such as the advanced glycation end products (AGE) and their receptors (RAGE) signaling pathway in diabetic complications and T- helper 17 (Th17) cell differentiation, among others. This elucidation of complex networks involving key genes like AKT Serine/Threonine Kinase 1 (AKT1), MYC proto-oncogene (MYC), tumor protein 53 (TP53), Interleukin 6 (IL6), and tumor necrosis factor (TNF) provides a promising foundation for the development of targeted therapies in the treatment of non-communicable diseases. Conclusion: These results show that G. italicus could be a natural source of potent antioxidants and enzyme inhibitors which need to be further explored for the development of biopharmaceuticals.
AtıfScopus15OpenAlex13İncele - MakaleAçık Erişim2025Scopus SJRQ1Muay Thai exercises improve quality of life, love of life and self-control
Şahin, Oktay; Yılmaz, Coşkun; Sezer, Süreyya Yonca; Şahin, Fatma Neşe; Ceylan, Levent; Çelikel, Baha Engin; Tan, Çetin; Akkuş Uçar, Mine; Kirikoğlu, Nagihan
Background: The existing research on Muay Thai sports has focused predominantly on the physiological effects of training, with limited attention devoted to the study of quality of life, love of life and self-control. The present study examined the effects of Muay Thai exercises on quality of life, love of life and self-control scores in healthy male subjects. Methods: The present study comprised 50 healthy sedentary male subjects. The subjects were randomly divided into two groups: one group engaged in Muay Thai training (MTT), while the other group served as a control group (CON). The sample sizes for the MTT and CON groups were both 25. The MTT group participated in basic Muay Thai training, while the CON group continued their normal life regime. The SF-12 quality of life scale, love of life scale and multidimensional self-control scale were administered before and after the six-week training period. Results: The study concluded that the six-week Muay Thai training program had a significant effect on quality of life levels, with 13.23% (p = 0.003) and 21.93% (p < 0.001) of participants demonstrating improvements in physical and mental scores, respectively. In terms of self-control levels, the program was found to have a significant effect on initiation and inhibition scores, with increases of 23.78% (p = 0.001) and 24.69% (p < 0.001), respectively. It was concluded that had a significant effect on the sub-dimensions of the Love of Life scale with increases of Positive Attitude Toward Life (PAWL) 18.63% (p < 0.001), Happy Results of the Love of Life (HRLL) 20.11% (p < 0.001) and Meaningfulness of Life (ML) 15.62% (p < 0.001), respectively. However, no significant differences were detected in any of the scales within the control group. Conclusion: Muay Thai exercises had a positive effect on quality of life, love of life and self-control levels in healthy male subjects. By providing valuable insights into how Muay Thai exercise affects quality of life, love of life, and self-control, this research can guide future intervention and program design in the context of sport psychology.
AtıfScopus7OpenAlex8İncele - MakaleYayıncıda açık erişim2025Scopus SJRQ2Effect of pre-freezing on motility, viability and abnormality of Nile tilapia fish Oreochromis niloticus sperm post cryopreservation
Muchlisin, Z.A.; Hasibuan, R.R.; Maulida, S.; Eriani, K.; Fadli, N.; Muhammadar, A.A.; Handayani, L.S.; Suharman, I.; Kocabas, M.; Kocabas, F.K.
Nile tilapia Oreochromis niloticus is a popular freshwater fish that has been extensively and intensively cultured worldwide. However, cryopreservation of its sperm, especially pre-freezing procedure, has not been properly developed. Therefore, the study aimed to determine the best pre-freezing procedure for cryopreservation of Nile tilapia Oreochromis niloticus sperm. The completely randomized design with five treatments and four replications was employed in this study. The tested treatments were T1=4°C → 0°C →-4°C →-10°C →-79°C →-196°C, T2=4°C→ 0°C →-4°C →-10°C →-196°C, T3=4°C → 0°C →-4°C →-196°C, T4=4°C → 0°C →-196°C), and T5=4°C →-196°C, with a 10 min equilibration at each respective temperature. Furthermore, sperm was cryopreserved for two weeks in liquid nitrogen (-179oC). The results of the ANOVA test showed that pre-freezing had a significant effect on sperm motility, and viability (P<0.05), but had no considerable impact on sperm abnormality (P>0.05). Treatment T4 exhibited higher motility and viability, but these values were not significantly different from T3 and T5. Based on practical consideration, it was recommended to utilize the T5 pre-freezing procedures (4°C →-196°C) for cryopreservation of Nile tilapia sperm. Considering these results, Nile tilapia sperm can be directly cryopreserved into liquid nitrogen after equilibration at 4°C for 10 min.
AtıfScopus1İncele - MakaleAçık Erişim2025Scopus SJRQ1The effect of 12 weeks of basic soccer training on violence tendency, psychological resilience, social anxiety in 12–14 years old children
Özcan, Büşra; Çelikel, Baha Engin; Erdoǧan, Ramazan; Karadaǧ, Mustafa; Aydoǧdu, Volkan; Uǧurlu, Fatih Mehmet; Bozkurt, Eyüp; Turan, Mehmet; Koçal, Meryem; Orhan, Serdar
Background: Regular exercise during childhood impacts not only physical development but also emotional stability, social adaptation, and behavioral control. Therefore, the present study aimed to examine the effects of a 12-week introductory football training programme on violent tendencies, psychological resilience, and social appearance anxiety in children aged 12–14. Methods: A randomized controlled design was used, with 40 children assigned to an experimental group (n = 20) or a control group (n = 20). The experimental group completed 60-min football sessions three times a week, while the control group did not participate in structured activity. The program included a 20-min warm-up, technical and tactical exercises, game-based activities, and a cool-down, targeting physical, technical, tactical, and psychosocial development. Data were collected using the VTS, PRS, and SAAS scales.Statistical analyses were performed using SPSS version 25 (IBM Corp., Armonk, NY, USA), with mixed-design ANOVA, significance set at p < 0.05, and effect sizes reported as partial eta-squared (ηp2). Results: No significant difference was observed in violence tendency scores in the experimental group (p = 0.939). However, a decrease was observed in psychological resilience scores in comparison to pre-test values, and this decrease approached the threshold of significance with a medium effect size (p = 0.153, ηp2 = 0.053). This finding suggests that the intervention may have a limited effect on psychological resilience. While no significant change was detected in the social appearance anxiety variable in the experimental group (p = 0.120), a significant decrease in anxiety levels was observed in the control group (p = 0.029). This finding suggests that factors other than the experimental intervention may have been effective in the control group. Conclusions: In conclusion, the 12-week football training programme demonstrated no significant short-term effect on violent tendencies or social appearance concerns, but may have a temporary effect on psychological resilience. The findings indicate that the impact of sports participation on psychosocial development in children is multifaceted and contingent on individual differences.
AtıfScopus3OpenAlex4İncele - MakaleAçık Erişim2025Scopus SJRQ1Investigating the relationship between digital citizenship levels and cyberbullying attitudes of university students
Karayol, Metin; Murathan, Talha; Erdoğan, Ramazan; Akarsu, Mehmet; Baş, Muhammet; Norman, Göktuğ
Background: This study examines the relationship between the levels of digital citizenship and attitudes toward cyberbullying among prospective physical education and sports teachers. Methods: This quantitative study adopted the relational survey model within its research framework. The sample consists of prospective physical education and sports teachers who studied in the Physical Education and Sports Teaching departments at universities during the 2022–23 academic year. The sample was determined using the convenience sampling method. The sample was administered a personal information form created by the researchers, as well as the Digital Citizenship Scale and the Cyberbullying Attitude Scale. Results: According to the MANOVA results for the Digital Citizenship and Cyberbullying Attitude scales, significant differences were found in the Digital Law, Digital Rights and Responsibilities, Approval and Anxiety subscales based on gender. However, the Pearson correlation analysis revealed no significant relationship between age and the subscales of the Digital Citizenship and Cyberbullying Attitude scales. However, the Pearson correlation analysis of the Digital Citizenship and Cyberbullying Attitude subscales revealed significant positive and negative relationships. Conclusion: The results of the path analysis of the digital citizenship scale and its subscales (identity concealment, enjoyment, approval and anxiety) showed that digital citizenship significantly predicted identity concealment, enjoyment, approval and anxiety.
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