Yazarlar
- Aglar, Erdal(14)
- Benzer, Fulya(14)
- Kocabaş, Mehmet(13)
- Sabanci, Serdal(12)
- Özçiçek, Esin(12)
- Icier, Filiz(10)
- Karaca Sanyürek, Nesrin(10)
- Kutluyer, Filiz(10)
- Kuzgun, Nermin Karaton(10)
- Topal, Murat(9)
- Aksu, Önder(8)
- Can, Erkan(8)
- Cevik, Mutlu(8)
- Kayim, Murathan(8)
- Dikici, Abdullah(7)
- Karakavuk, Emrah(7)
- Kizak, Volkan(7)
- Kocabas, Mehmet(7)
- Macit, Arife(7)
- Ozturk, Burhan(7)
- Öbek, Erdal(7)
- Erişir, Mine(6)
- Ertekin, Özlem(6)
- Gundogdu, Muttalip(6)
- Ince, Muharrem(6)
- Omac, Basri(6)
- Sabancı, Serdal(6)
- Yaman, Mehmet(6)
- Aydın, Sevinç(5)
- Erguven, Gokhan Onder(5)
- Erisir, Mine(5)
- Erol, Nida Demirtas(5)
- Goksu, Ali(5)
- Kizil, Mevlude(5)
- Kutluyer Kocabaş, Filiz(5)
- Serdar, Osman(5)
- Yilmaz, Ökkeş(5)
- Çimen, Murat(5)
- Şeker, Engin(5)
- Altınterim, Başar(4)
Yayınlar
- MakaleAçık Erişim2023Scopus SJRQ3The effect of different boron compounds on nutrient digestibility, intestinal nutrient transporters, and liver lipid metabolism
Şahin, Emre; Orhan, Cemal; Erten, Füsun; Şahin, Fikrettin; Şahin, Nurhan; Şahin, Kazim
Background/aim: Gastrointestinal health is essential for maintaining a healthy lifestyle. Improving nutrient absorption and energy metabolism are the critical targets for intestinal health. This study aimed to determine the effects of different boron (B) derivatives on nutrient digestibility, intestinal nutrient transporters, and lipid metabolism in rats. Materials and methods: Twenty-one rats were allocated to three groups (n = 7) as follows: (i) Control, (ii) Sodium pentaborate pentahy-drate (SPP), and (iii) boric acid (BA). The rats were fed a chow diet (AIN-93M) and supplemented with 8 mg/kg elemental B from SPP (45.2 mg/kg BW) and BA (42.7 mg/kg BW) via oral gavage every other day for 12 weeks. The nutrient digestibility of rats in each group was measured using the indigestible indicator (chromium oxide, Cr2 O3, 0.20%). At the end of the experiment, animals were decapitated by cervical dislocation and jejunum, and liver samples were taken from each animal. The nutrient transporters and lipid-regulated transcription factors were determined by RT-PCR. Results: The nutrient digestibility (except for ash) was increased by SPP and BA supplementation (p < 0.05). SPP and BA-supplemented rats had higher jejunal glucose transporter 1 (GLUT1), GLUT2, GLUT5, sodium-dependent glucose transporter 1 (SGLT1), fatty acid transport protein-1 (FATP1), and FATP4 mRNA expression levels compared to nonsupplemented rats (p < 0.0001). BA-supplemented rats had remarkably higher peroxisome proliferator-activated receptor gamma (PPARγ) levels than nonsupplemented rats (p < 0.0001). In contrast, sterol regulatory element-binding protein 1c (SREBP-1c), liver X receptor alpha (LxR-α), and fatty acid synthase (FAS) levels decreased by SPP supplementation compared to other groups (p < 0.05). Conclusion: SPP and BA administration enhanced nutrient digestibility, intestinal nutrient transporters, and liver lipid metabolism in rats.
AtıfScopus8WoS7OpenAlex9TR Dizin1
İncele - Derleme MakaleAçık Erişim2023Scopus SJRQ3Obtaining haploid plants by irradiated pollen culture in oil seed crops
Yaman, Hümeyra; Sanyürek, Nesrin Karaca
Haploid plant production is of great importance to shorten the breeding period in plant breeding programs. Obtaining pure lines in plant growing programs require an intensive work with huge labor and time. Obtaining one hundred percent homozy-gous pure lines is a key point for the improvement and development of new cultivars. Haploid plants with a single set of homozygous chromosomes have become a valuable tool in plant breeding. Dihaploid plants that are homozygous at all loci with dou-bling of their chromosomes can be propagated by seed and reach full homozygosity in a single generation. Traditional methods take seven years to reach homozygosity. Dihaploidization methods provide significant advantages in terms of gaining homozy-gosity in a short period of one year and bringing pure lines into agriculture. Anther culture and irradiated pollen technique are among the most widely used techniques in this respect; where physical or chemical agents are used to induce mutated pollen grains and anthers that are subsequently employed to develop dihaploids through in vitro cultures. These techniques are a good source to facilitate gene mapping, cyto-genetic research, and evolutionary studies. Irradiated pollen culture techniques have been applied to many oilseed crops to obtain pure lines. This study highlights some salient features of producing dihaploids using irradiated pollen grains and their maintenance.
AtıfScopus1OpenAlex2TR Dizin1İncele - MakaleAçık Erişim2023Scopus SJRQ1Evaluation of pea/rice and amylopectin/chromium as an alternative protein source to improve muscle protein synthesis in rats
Ozdemir, Oguzhan; Erten, Fusun; Er, Besir; Orhan, Cemal; Komorowski, James R.; Sylla, Sarah; Perez Ojalvo, Sara; Sahin, Kazim
Background: A preclinical study reported that the combination of an amylopectin/chromium complex (ACr) of branched-chain amino acids (BCAA) significantly enhanced muscle protein synthesis (MPS). This study was conducted to determine the effects of the addition of ACr complex to a pea/rice (PR) protein on MPS, insulin, muslin levels, and the mTOR pathway in exercised rats. Methods: Twenty-four rats were divided into three groups: (i) exercise (Ex); (ii) Ex + PR 1:1 blend (0.465 g/kg BW); (iii) Ex + PR + ACr (0.155 g/kg BW). On the day of single-dose administration, after the animals were exercised at 26/m/min for 2 h, the supplement was given by oral gavage. The rats were injected with a bolus dose (250 mg/kg BW, 25 g/L) of deuterium-labeled phenylalanine to determine the protein fractional synthesis rate (FSR) one h after consuming the study product. Results: The combination of PR and ACr enhanced MPS by 42.55% compared to the Ex group, while Ex + PR alone increased MPS by 30.2% over the Ex group (p < 0.0001) in exercised rats. Ex + PR plus ACr significantly enhanced phosphorylation of mTOR and S6K1 (p < 0.0001), and 4E-BP1 (p < 0.001) compared to the Ex (p < 0.0001). PR to ACr also significantly increased insulin and musclin levels (p < 0.0001) in exercised rats. Additionally, compared to Ex + PR alone, Ex + PR + ACr enhanced mTOR (p < 0.0001) and S6K1 (p < 0.0001) levels. Conclusion: These data suggested that PR + ACr may provide an alternative to animal proteins for remodeling and repairing muscle by stimulating MPS and mTOR signaling pathways in post-exercised rats. More preclinical and clinical human studies on combining pea/rice and amylopectin/chromium complex are required.
AtıfScopus4OpenAlex4İncele - MakaleYalnız künye2023Scopus SJRQ1Acrylamide formation in apple juice concentrates during storage
Aktağ, Işıl Gürsul; Gökmen, Vural
This study investigated the acrylamide formation in model systems, laboratory-scale produced apple juice concentrates obtained from different stages of process, and commercial apple juice concentrates at different Brix levels during the storage. Changes in the concentrations of reducing sugars, asparagine, 5-hydroxymethylfurfural, 3-deoxyglucosone, and acrylamide were monitored. In addition, Schiff bases of 3-deoxyglucosone and 5-hydroxymethylfurfural with asparagine were confirmed using high-resolution mass spectrometry in order to understand the contribution of intermediates to acrylamide formation. The results revealed that acrylamide formed in both acidic-aqueous model systems and laboratory-scale apple juice concentrates during production. The concentrations of 3-deoxyglucosone, 5-hydroxymethylfurfural, and acrylamide increased significantly (p < 0.05) with the increase in Brix levels whereas asparagine levels decreased in commercial apple juice concentrates during storage. The concentration of acrylamide reached at the maximum level of 0.30 ± 0.02 µmol/kg dry matter in 70°Bx of the concentrates. The findings showed that long-term storage of apple juice concentrates at high Brix levels contributes the acrylamide formation even in unsuitable systems such as acidic and high moisture medium. The confirmation of Schiff base of 3-deoxyglucosone and 5-hydroxymethylfurfural with asparagine demonstrated that the acrylamide formation was attributed to the accumulation of intermediates leading to the conversion of asparagine to acrylamide.
AtıfScopus9WoS8OpenAlex9İncele - MakaleYalnız künye2023Scopus SJRQ1Effect of type and concentration of cryoprotectant on the motility, viability, and fertility of climbing perch Anabas testudineus Bloch, 1792 (Pisces: Anabantidae) sperm
Maulida, Siti; Eriani, Kartini; Fadli, Nur; Kocabaş, Filiz Kutluyer; Siti-Azizah, Mohd Nor; Wilkes, Martin; Muchlisin, Zainal Abidin
The climbing perch, Anabas testudineus is a freshwater fish that has economic value in Indonesia. It is cultured in the country, but the breeding technology, specifically sperm storage, is not well developed. Sperm cryopreservation is one of the preservation methods that need to be developed to support fish breeding technology. The type of cryoprotectants and its concentration are species-dependent and determines the success of this approach. Therefore, this study is aimed at determining the optimal type and concentration of cryoprotectant for sperm cryopreservation of A. testudineus. Four separate study series were performed, each of which evaluated one type of cryoprotectant at five concentration levels. The cryoprotectants used were DMSO, methanol, glycerol, and ethanol, and the tested concentrations were 0%, 5%, 10%, 15%, and 20%, which were combined with 5% egg yolks. Each treatment was conducted with three replications. The results showed that the type of cryoprotectant and its concentration significantly affected sperm motility, viability, and fertility of climbing perch (P < 0.05). The best outcome was obtained in DMSO, and methanol at a concentration of 10%, glycerol at 5%, and ethanol at 15%. However, the highest motility, viability, and fertility values were observed at 10% DMSO, indicating it is the best type and concentration for sperm cryopreservation of climbing perch A. testudineus.
AtıfScopus10WoS7OpenAlex11İncele - MakaleYalnız künye2023Scopus SJRQ3Comprehensive Evaluation of the Relationships Between Grape Skin Color/Ripening Time and Antioxidative Capacity, Some Phytochemicals, and Fatty Acid Compositions of Their Seeds
Çakır, Atilla; Odabaşıoğlu, Mehmet İlhan; Karaca Sanyürek, Nesrin; Aydın, Sevinç
It has been proven that grapes, which are widely cultivated around the world, have positive health effects. However, the phytochemical composition of lesser-known local varieties of Vitis vinifera L., which has a very wide range of varieties, is still being studied. The aim of this study was to determine the effects of skin color and ripening time on the phytochemical compositions of grape seeds. As a plant material local grape varieties cultivated in Southeastern Anatolia (Turkey) were used. The results showed that grape skin color has an effect on vitamin K1, vitamin K2, vitamin D3, δ‑tocopherol, stigmasterol, ergosterol, myristic acid, oleic acid, trans-elaidic acid, and the monounsaturated fatty acid (MUFA) and saturated fatty acid (SFA) contents of seeds. The seeds of grape varieties with colored skins were richer in K2, D3, stigmasterol, oleic acid, trans-elaidic acid, and MUFAs, while the seeds of grape varieties with white skins were richer in K1, δ‑tocopherol, ergosterol, and SFAs. The ripening time of the grapes was found to have a partial effect on the fatty acid compositions of the seeds, but without any effect on linoleic acid contents. As the ripening time was delayed, there was an increase in oleic acid and MUFA contents of the seeds, while there was a decrease in SFA contents. In general, increased vitamin K1 contents of the seeds were parallel to decreases in vitamins K2, D2, and D3, as well as α‑tocopherol content and antioxidant activity. The seeds of grape varieties that have colored skins were found to have more suitable compound compositions for use in the production of functional foods that support human and animal health. In addition, it was concluded that grape berries that ripen late may be more favorable for grapeseed oil production.
AtıfScopus3WoS4OpenAlex3İncele - MakaleYalnız künye2023Scopus SJRQ1Energy, exergy and cost analysis of different hemispherical solar distillers: A comparative study
Hadi Attia, Mohammed El; Hussein, Ahmed Kadhim; Radhakrishnan, Ganesh; Vaithilingam, Sivakumar; Younis, Obai; Akkurt, Nevzat
The experimental study of the results of reflective aluminum foils, metal sheets, and phosphate granules on the productivity and efficiency of hemispherical solar stills was given throughout this work under the solar conditions of the city of El-Oued (Algeria). Solar stills were designed, manufactured, and tested in August 2020. A standard hemispherical solar still was made of wood and coated with black silicon. It was considered a traditional solar still. Although it was compared to traditional solar stills, it was improved by covering its side walls with reflective aluminum foil, zinc metal sheets, and copper sheets. It had been found that the productivity of the modified still was 8.67%, 29.08%, and 42.35%, respectively, on top of that of the traditional solar still. This could be due to the activity of the foils and metals, which reflect more radiation and store energy, increasing the temperature of the salt water in the basin. In the second experiment, three modified solar stills in line with aluminum foil and phosphate granules (30 g/L), zinc metal sheet and phosphate granules, and copper metal sheet and phosphate granules were collectively used. It had been found that the productivity of the modified solar still with aluminum foil and phosphate granules (the improvement rate is 30.61%) was on the far side of that with zinc metal sheets and phosphate granules (the improvement rate is 49.961%) and copper metal sheets and phosphate granules (the improvement rate is 62.24%).
AtıfScopus37OpenAlex34İncele - MakaleYalnız künye2023Scopus SJRQ2Genotoxic effect of iron oxide (Fe2O3) nanoparticles on Triticum aestivum (wheat)
Tasar, Neslihan
Industrial activities and unconscious consumption of natural resources cause environmental pollution with the rapid increase in the world population. As a result of the widespread use of iron oxide nanoparticles (Fe2O3 NP) with nano-industrial activities, it is predicted that this NP will accumulate in the air, water, and soil. In the present study, the purpose was to find out the genotoxic effects on root meristem cells of the Triticum aestivum L. plant, which is an indicator organism exposed to 20–40 nm Fe2O3 NPs at different concentrations (100, 200, and 400 ppm). The amount of Fe2O3 NP accumulated in T. aestivum used in the study was determined with x-ray diffraction (XRD) spectroscopy, scanning electron microscopy (SEM), SEM element map, and EDS characteristic spectrum. All concentrations of Fe2O3 NP caused significant decreases in the mitotic index. Fe2O3 NPs significantly increased the frequency of mitotic abnormalities in T. aestivum root tip cells at all treatment times and all concentrations when compared to the control. Fe2O3 NPs were formed by various mitotic abnormalities such as loss of genetic material, deconstructed prophase, adhesion, chromosome groupings in metaphase, deconstructed metaphase, C-Metaphase, chromosomal loss, chromosomal fracture, polyploidy, deconstructed anaphase, lagging chromosome, fragment, polar deviation, bridging, propagation, asynchronous division, star anaphase, multipolarity, and deconstructed telophase. All these results show that Fe2O3 NPs are genotoxic and clastogenic and may also cause DNA damage. Briefly, these data show that Fe2O3 NPs taken by organisms may pose a danger to the organism and the upper consumer. These findings also show that the production and use of Fe2O3 NPs, which affect organisms, must be controlled, and ultimately, be safely disposed of to reduce their bioaccumulation. Research Highlights: In the present study, the purpose was to find out the genotoxic effects on root meristem cells of the Triticum aestivum L. (bread wheat) plant, which is an indicator organism exposed to 20–40 nm Fe2O3 NPs at different concentrations (100, 200, and 400 ppm). The amount of Fe2O3 NP accumulated in T. aestivum used in the study was determined with x-ray diffraction (XRD) spectroscopy, scanning electron microscopy (SEM), SEM element map, and EDS characteristic spectrum. The mitotic index was calculated to reveal the genotoxic effect. “Loss of genetic material, deconstructed prophase, adhesion, chromosome groupings in metaphase, deconstructed metaphase, C-Metaphase, chromosomal loss, chromosomal fracture, polyploidy, deconstructed anaphase, lagging chromosome, fragment, polar deviation, bridging, propagation, asynchronous division, star Chromosomal abnormalities such as anaphase, multipolarity, and deconstructed telophase” were visualized. Fe2O3 NPs are genotoxic and clastogenic and may also cause DNA damage.
AtıfScopus10WoS7OpenAlex11İncele - MakaleAçık Erişim2022Zebra Midye (Dreissena polymorpha)'de Malathionun Akut Toksisitesi (LC50)’nin Belirlenmesi
Serdar, Osman; Ödün, Neşe Akçanal
Sunulan çalışmada, zebra midye (Dreissena polymorpha) bireyleri, LC50 değerlerinin belirlenmesi için, konsantrasyon düzeyleri farklı olan, malathion etken maddesini içeren pestisitin bu organizma üzerindeki akut toksik etkisi araştırılmıştır. Bu amaçla aralık belirleme ve deneysel tasarım kurgulanmıştır. Tüm deneyler (aralık belirleme dahil) 2 litre hacimli cam kaplar içerisine 1 litre su katılarak yapılmıştır. Her akvaryum içerisine, 10’ar adet D. polymorpha bireyi eklenerek, deneme çalışması hazırlanmıştır. LC50 değerinin belirlenmesi için gözlem periyodu olarak, 24 saatlik zaman dilimindeki D. polymorpha bireylerinin canlılık durumları incelenerek kayıt altına alınmıştır. Canlılık özelliğini yitiren D. polymorpha bireyleri deneme ortamından çıkarılmıştır. Bu şekilde 3 tekrarlı olarak yürütülen çalışmada, malathion etken maddeli pestisitin D. polymorpha için LC50 değeri 120,11 ± 19,32 mg/l olarak belirlenmiştir.
AtıfOpenAlex1İncele - MakaleAçık Erişim2022An Ethnobotanical Research on Plants Used for Food Purposes in Bigadiç (Balıkesir-Turkey)
Cakilcioglu, Ugur; Satıl, Fatih; Tanaydın, Gökhan
In this study, the ethnobotanical properties of the plants used by the local people for food in Bigadiç province were investigated. The study was carried out in fifteen rural neighborhoods and two district markets. A total of 104 resource persons, 76 men and 28 women, were interviewed. These plants, which are used among the people, were also identified and collected in their natural environments and their herbariums were made. As a result of the research, it was determined that a total of 51 taxa belonging to 26 families in the region were used for food purposes. The first five families of plants used as food are as follows: Rosaceae (18%), Lamiaceae (12%), Cucurbitaceae (7%), Fabaceae (7%), Moraceae (7%) and others (%41). The first five genera, which are most commonly used by the public, are listed as follows: Triticum (21), Sesamum (19), Origanum (17), Portulaca (14) and Vitis (14). Mostly fruit/seed (32), leaf (17) and root/stem (3) parts of these plants are used by the public. In the study, the plants that people use as food mostly; eating in the kitchen (22), fruit and fruit juice (21), spice (7), medicinal tea (5), oil (4) and molasses/jam (3). As a result of the study, more diversity was observed in the use of wild plants as food, especially in rural.
AtıfOpenAlex7TR Dizin2İncele - MakaleAçık Erişim2022Dimethoate ve Malathion Pestisitlerinin Dreissena polymorpha (Pallas, 1771) Üzerindeki Kombine Etkisinin Sitokrom P450 ve Asetilkolinesteraz Kullanılarak Belirlenmesi
Serdar, Osman; Yildirim, Nuran Cikcikoglu; Yildirim, Numan
Bu çalışmada, Dreissena polymorpha’da organofosforlu dimethoate ve malathion etken maddeli insektisit karışımlarının toksisitesini ortaya çıkarmak için sitokrom P450 (CYP1A1) ve Asetilkolinesteraz (AchE) aktiviteleri ölçülmüştür. Dimethoate ve malathion'un öldürücü konsantrasyonu (LC50) 96 saat maruziyet sonunda 40,82±2,54 mg/L olarak hesaplanmıştır. D. polymorpha dimethoate ve malathionun üç subletal konsantrasyonuna (LC50 değerine 1/16, 1/8 ve 1/4 oranla) 24 saat ve 96 saat boyunca maruz bırakılmıştır. CYP1A1 ve AChE seviyeleri, ticari kit kullanılarak mikroplaka okuyucuda ölçülmüştür. AChE aktivitelerinin kontrol grubuna göre 96 saat sonra tüm maruziyet gruplarında düştüğü gözlenmiştir. Maruziyet süreleri karşılaştırıldığında 96. saat sonunda enzim aktivitelerinde istatistiksel olarak anlamlı bir değişiklik olmadığı belirlenmiştir. Tüm gruplarda 24 saatin sonunda CYP1A1 seviyelerinde istatistiksel olarak anlamlı bir değişiklik olmamıştır, ancak kontrol grubuna kıyasla 96 saat sonra azalma görülmüştür (p0,05). Dimethoate ve malathion kombinasyonunun toksik yanıtı konsantrasyonlarına bağlı olarak değişebildiği tespit edilmiştir. Sonuç olarak, dimethoate ve malathion karışımlarının, D. polymorpha'da AChE ve CYP1A1 aktivitelerini inhibe ettiği ve bu enzimlerin etkili bir biyobelirteç olarak kullanılabileceği ortaya konmuştur.
AtıfOpenAlex1İncele - MakaleAçık Erişim2022Investigation of Antigenotoxic Effects of Althaea officinalis L. in Drosophila Melanogaster
Karabulut, Aygul Kılıç
In this study, the antigenotoxic effect of Althaea officinalis L., which is a medicinal plant and is widely used in the treatment of many diseases, was studied. For this reason, the Drosophila wing spot test (SMART), an in vivo test that measures somatic mutation and recombination, was used. The antigenotoxic effect of A. officinalis against the mitomycin C (MMC) mutagen was investigated. After application studies, it was determined that 5 mg, 15 mg and 45 mg doses of dried herba of A. officinalis, could suppress DNA damage caused by MMC. As a result of the application of 5mg, 15mg and 45mg doses it was determined that the total number of spots induced by MMC was inhibited by 3.66%, 1.83% and 2.03%, respectively. According to the data obtained, it is thought that A. officinalis contains some antigenotoxic factors.
- MakaleAçık Erişim2022Endemik Stachys tundjeliensis Kit Tan & Sorger (Lamiaceae)’ in Uçucu Yağ Bileşenleri ve Kemotaksonomik Bir Yaklaşım
Yüce, Ebru
Bu araştırmada, Tunceli’ de doğal olarak yetişen endemik Stachys tundjeliensis Kit Tan & Sorger bitkisinin toprak üstü kısımlarından su distilasyonu ile elde edilen uçucu yağ bileşenlerinin tespiti yapılmıştır. Çalışma ile bitkinin uçucu yağ bileşenlerini tespit ederek tür ve cinsin taksonomisine katkıda bulunmak amaçlanmıştır. Çalışma materyali 2021 yılında Tunceli-Ovacık arasında çiçekli olarak toplanarak kurutulup hazır hale getirilmiştir. 100 g bitki örneğinden su distilasyonu yöntemi ile Clevenger aparatı kullanılarak 3 saat distile işlemi sonucu uçucu yağ elde edilmiştir. Analiz için GC/MS (Gaz Kromatografi/Kütle Spektrometresi) cihazı kullanılmıştır. Elde edilen uçucu yağda toplam 29 bileşen belirlenmiştir. Okaliptol (%28.9), timol (%14.3), 4 karvomethanol (%12.5), d-piperiton (%11.2), pinen (%6.3) ve terpineol (%5.7) yüksek orandaki bileşenlerdir. Bu bileşenlerden okaliptol/timol kemotip olarak düşünülebilir.
AtıfOpenAlex1İncele - MakaleAçık Erişim2022Enzymatic and Bibliometric Analysis of Bifidobacterium sp. of Probiotic Origin in The Based Digestive Tract of Honey Bees
Yazdıç, Fadime; Kar, Bülent; Karaman, Altuğ; Yücel, Halit; Ekinci, Kübra
Honey bees (Apis mellifera) are a unique super organism that produces products such as honey, pollen, royal jelly, propolis, beeswax and bee venom and serves as a vector for pollination of many natural and industriyal plants. The effect of intestinal microflora and, accordingly, the immune system come to the fore among the causes of colony losses that have occurred recently. The diversity and densities of bacteria in the digestive tube of bees are affected by their immune systems. In order for this effect to be positive, the intestinal microflora must be natural and balanced. The enzyme activity of the probiotic-derived Bifidobacterium sp., which has an important place among the bacterial populations in the intestine, has a critical effect on both other symbiont microorganisms and the nutrition of the host. Therefore, in this study, both glikozide hidrolase enzyme activity analysis and bibliometric analysis were performed to emphasize the importance of Bifidobacterium sp. Different pH, temperature and substrates were preferred to calculate the optimum enzyme activity. As a result of the analysis of the enzyme activity, the glycoside hydrolase activity (pH 5.0 and 30oC) of Bifidobacterium sp. was determined. Further use of inulin substrate has shown that it is a natural prebiotic source for this probiotic microorganism. At the same time, the hydrolysis of xylan, which is known as a new generation prebiotic source, has also taken place. For bibliometric analysis, correlation links in Web of Science and Scopus database were concluded with the help of VOS viewer software
AtıfOpenAlex2TR Dizin1İncele - MakaleAçık Erişim2022Tunceli Uzunçayır Baraj Gölü’ndeki Kababurun (Chondrostoma regium, (Heckel, 1843)) Balıklarının Et Veriminin Belirlenmesi
Yüksel, Fahrettın; Demirol, Ferhat; Kurt Kaya, Gülderen; Gündüz, Fatih
Bu çalışma, Uzunçayır Baraj Gölü’nden avlanan kababurun balığı (Chondrostoma regium, (Heckel, 1843))’nın et verimliliğini belirlemek amacıyla yürütülmüştür. Bu amaçla çalışmada, C. regium türüne ait yaşları I-VIII arasında dağılım gösteren 100 adet balık kullanılmış olup, et verimliliği ile farklı vücut kısımları arasındaki ilişkiler incelenmiştir. İncelenen örneklerde, ortalama yüzgeç ağırlığı, omurga ağırlığı, deri ağırlığı, baş ağırlığı, iç organ ağırlığı ve tüketilebilir kısımların vücut ağırlığına göre yüzde oranları sırasıyla %1,72, %3,57, %7,50, %10,55, %9,94 ve %66,72 olarak belirlenmiştir. Çalışmanın sonunda kababurun örneklerinde en yüksek tüketilebilir et oranının III. yaş grubunda (%67,91), en düşük et oranının ise I. yaş (%62,04) grubunda olduğu belirlenmiştir.
- MakaleAçık Erişim2022Türkiye’ de Yayılış Gösteren Hypericum L. Cinsine Ait 3 Taksonun Uçucu Yağ Bileşenleri
Gedik, Osman; Kurşat, Murat; Tasar, Neslihan
Bu çalışmada ülkemizin biyolojik zenginliklerinin önemli bir parçası olan ve doğal habitatlarından toplanan Hypericum L. cinsine ait Hypericum uniglandosum Hausskn. ex Bornm., Hypericum microcalycinum Boiss. & Heldr. ve Hypericum scabroides N. Robson & Poulter türleri uçucu yağ bileşenleri yönünden araştırılmıştır. Bu türlerden Hypericum uniglandosum ve Hypericum scabroides türleri endemik türdür. Çalışmada kullanılan bitkiler temmuz- ağustos ayında çiçekli dönemde iken toplanarak uçucu yağ bileşenleri yönünden araştırılmıştır. Analiz sonuçlarına göre 14 farklı bileşen tespit edilmiştir. Bitki örnekleri ile yapılan analiz sonuçlarına göre en çok bulunan bileşen; H. uniglandosum’ da; % 90.25, H. microcalycinum’ da; % 91.46 ve H. scabroides’te; % 91.77 olarak alpha-pinene olmuştur. Bu bileşenden başka değişik oranlar olmakla birlikte beta-pinene, beta-myrcene, limonene, cymene gibi çeşitli bileşenler de analiz sonuçlarına göre rapor edilmiştir. Çalışma materyalimizi oluşturan bitkiler üzerinde farklı oranlarda, farklı bileşenler tespit edilmiştir. Ayrıca çalışmamızı oluşturan H. uniglandosum ve H. scabroides türleri endemik tür olduğu için uçucu yağ analizlerinin belirlenmesinin önem arz ettiği düşünülmektedir.
- MakaleYalnız künye2022Comparison of Some Physical and Chemical Properties of Kefir Obtained from Different Kefir Cultures and Brands of Milk
Ince, Muharrem; Ince, Olcay Kaplan; Eryilmaz, Haydar
In this study, three different kefir cultures were used to ferment five different brands of milk samples. pH, the dry matter, ash amount, carbon dioxide (CO2) amount, titratable acidity, 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging capacity, the reducing power, the Fe(II) ions chelating capacity, the total phenolic content (TPC), copper(II) ion reductive antioxidant capacity (CUPRAC) and mineral matter contents were investigated in kefir samples and results were evaluated statistically. When kefirs’ CUPRAC, TPC, DPPH free radical scavenging capacity, Mg, Zn, and Na concentrations are evaluated in terms of kefir culture, KC1, KC2, KC3, KC1, KC1, and KC1, had the highest values (p<0.05), respectively. If it is evaluated in terms of different brands of milk, kefirs’ CUPRAC, TPC, DPPH free radical scavenging capacity and Na concentrations were found highest (p<0.05) which were produced by M5, M2, M1, and M4, respectively. The data obtained from the experimental studies it was determined that the kefir cultures and milk used had an effect on the quality of the kefir.
AtıfOpenAlex3TR Dizin2İncele - MakaleAçık Erişim2022Etkili Girdi Parametrelerinin Çoklu Regresyon ile Belirlendiği Su Sertliğinin ANFIS Yöntemi ile Tahmin Edilmesi
Acar, Ramazan; Saplioglu, Kemal
Su sertliği; özellikle içme suları, endüstri suları ve hizmet suyu alanlarında kullanım hususunda önemli bir kalite özelliğidir. Kalsiyum (Ca), magnezyum (Mg) ve bikarbonat (HCO3) tuzları ile suyun geçici sertliği; klor (CL), fosfat (PO43), nitrat (NO3), sülfat (SO4) ve silikat tuzlarıyla da suyun kalıcı sertliği oluşmaktadır. Çalışmada, Fırat Havzası üzerinde bulunan 2119 nolu Kemahboğazı akım gözlem istasyonu (AGİ) için Anfis modelleri ile su sertliğinin tahmin edilmesi amaçlanmıştır. Bu amaçla Na, K, CO3, HCO3, CL, SO4, EC, sıcaklık (T), pH ve su miktarı (SM) verileri girdi olarak kullanılmıştır. Ancak modeller oluşturulurken parametre sayısının fazla olması kurulacak Anfis modellerinin sayısını arttırmakta ve bu modeller içerisinden en iyi modeli seçmeyi de zorlaştırmaktadır. Bu zorluğun üstesinden gelebilmek için Anfis modellerinde kullanılacak etkili parametrelerin belirlenebilmesi için çoklu regresyon modeli kurulmuştur. Oluşturulan çoklu regresyon modeline her parametre sırası ile eklenerek Düzeltilmiş R² değerlerindeki değişmeler gözlemlenerek Anfis modelinde kullanılacak etkili parametreler belirlenmiştir. Çoklu regresyon sonucu girdi parametrelerinin CL, EC, HCO3 ve SO4 olarak seçilmesine karar verilmiştir. Çalışmanın ikinci kısmında bu parametrelerin farklı kombinasyon ve alt küme sayıları ile Anfis modellemeleri oluşturulmuştur. Tüm sonuçlar eğitim ve test verileri için R², ağırlıklı karesel hata ve Wilcoxon testi değerleri belirlenmiş ve su sertliğinin belirlenmesinde kullanılabilecek modeller gösterilmiştir.
AtıfOpenAlex8TR Dizin5İncele - MakaleAçık Erişim2022Immunomodulation function of Tunceli garlic (Allium tuncelianum) oil in Rainbow Trout (Oncorhynchus mykiss)
Ispır, Ünal; Özcan, Mikail; Şeker, Engin
The effects of injectable Tunceli garlic oil (Allium tuncelianum) on serum response of rainbow trout were examined. Influence of intraperitoneal (i.p.) injection administration of Tunceli garlic oil (TGO) was evaluated on some immunological factors of rainbow trout. Fish weight 40 g were i.p. injected TGO at doses of 1% and 10%. Serum lysozyme activity, bactericidal activity, myeloperoxidase, protein and immunoglobulin levels were measured on days 3, 7, 14 and 21 after the TGO administration. All the immune parameters assayed remained affected when TGO was i.p. administered. Serum bactericidal activity was consistently achieved by immunizing fish with TGO. Levels of serum myeloperoxidase activity were increased in the groups of fish injected with TGO. Myeloperoxidase and bactericidal activities peaked at 14 and 21 days post-injection, respectively. Lysozyme activity was significantly increased throughout experiment in the all groups. Total protein and immunoglobulin levels increased in the 21 days post-injection although no statistically significant differences. In conclusion, these results suggest that there are functionally effects of TGO on the immune mechanisms of rainbow trout.
AtıfOpenAlex2TR Dizin1İncele - MakaleAçık Erişim2022Anatomical, Micromorphological, Karyological and Biochemical study of Scutellaria orientalis subsp. virens and Scutellaria salviifolia
Acar, Mikail; Tasar, Neslihan; Akbulut, Guelcin Beker
In this study, the anatomical and micromorphological structure, karyological characteristics and biochemical content of Scutellaria orientalis subsp. virens and endemic Scutellaria salviifolia, whose distributions areas overlap, were compared. Some anatomical and micromorphological differences were observed on the taxa; scleranchymatic pericycle layer on the stem, stomata density, distribution of trichomes, as well as the main vascular bundle and general shape of the petiole. The chromosome numbers of both taxa were determined as 2n = 22. However, there was a difference between chromosome length range and total chromosome length. The chromosome numbers and chromosome morphologies of these species have been defined for the first time in this paper. Differences in biochemical content were observed between species. Chlorophyll a (Chl a), total chlorophyll (Total Chl), total carbohydrate and malondialdehyde (MDA) contents were determined higher in leaf and stem samples of S. orientalis subsp. virens than S. salviifolia. There was no significant difference between the two taxa in terms of chlorophyll b (Chl b) content. Carotenoid (Car) content was detected higher in leaves samples of S. orientalis subsp. virens, but no significant difference was found between stems samples. Also, the effect of taxa on biochemical contents in relation to the habitat they live in is given in this study.
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