Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleAçık Erişim2025Scopus SJRQ1
    Assessing Motor Performance and Ankle Mobility in Pre-Adolescent Male Fencers

    Aydin, Yalcin; Tokgoz, Gurkan; Yilmaz, Nurkan; Coskun, Ilgin Ali; Beykumul, Aysegul; Colak, Enes; Aygoren, Caner; Koc, Samet; Cinarli, Fahri Safa

    Ankle mobility plays a critical role in dynamic stability and propulsion during fencing-specific actions. However, its relationship to performance metrics in young athletes remains unclear. This study aimed to investigate the relationship between ankle range of motion (ROM), acceleration, and jump height in pre-adolescent male fencers, as well as to examine bilateral differences in ankle mobility between the front and rear foot. Fifteen fencers (age 10.86 ± 0.91 years) were assessed for ankle ROM (dorsiflexion, plantar flexion, inversion, eversion) using a goniometer. Performance tests included a 7 m sprint lunge (acceleration) and countermovement jump. Significantly large correlations were observed between front and rear foot ankle plantar flexion range of motion and both acceleration (r = 0.625–0.628, p < 0.05) as well as vertical jump height (r = 0.579–0.647, p < 0.05). Rear foot ankle plantar flexion range of motion significantly predicted acceleration (r2 = 0.335, p < 0.05) and jump height (r2 = 0.418, p < 0.05). In contrast, no meaningful associations were found between dorsiflexion, inversion, or eversion range of motion and performance metrics. Additionally, bilateral comparisons revealed significantly greater dorsiflexion in the front foot ankle and greater eversion in the rear foot ankle (p < 0.05). Plantar flexion ROM is a key contributor to acceleration and jump capacity in youth fencers. Incorporating ankle mobility training may support physical development in this population.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus2WoS2OpenAlex2
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2025Scopus SJRQ1
    Effects of Integrated Extracts of Trigonella foenum-graecum and Asparagus racemosus on Hot Flash-like Symptoms in Ovariectomized Rats

    Erten, Fusun; Er, Besir; Ozmen, Ramazan; Tokmak, Muhammed; Gokdere, Ebru; Orhan, Cemal; Morde, Abhijeet A.; Padigaru, Muralidhara; Sahin, Kazim

    Vasomotor symptoms, such as hot flashes (HFs), commonly affect women during menopause, leading to a reduced quality of life. The current study evaluates the combined effect of active components Asparagus racemosus (AR) and Trigonella foenum-graecum (TFG) in a single oral formulation (IAT) for alleviating menopausal symptoms in ovariectomized rats. Following bilateral ovariectomy, the animals were randomly assigned to nine groups: (1) Control, (2) Ovariectomy (OVX), (3) OVX+TA1 (TA: Combination of Trigonella and Asparagus; TFG 30 mg/kg + AR 30 mg/kg), (4) OVX+TA2 (TFG 30 mg/kg + AR 15 mg/kg), (5) OVX+TA3 (TFG 15 mg/kg + AR 30 mg/kg), (6) OVX+TA4 (TFG 40 mg/kg + AR 30 mg/kg), (7) OVX+TA5 (TFG 30 mg/kg + AR 40 mg/kg), (8) OVX+IAT1 (IAT: Integrated Asparagus and Trigonella; TFG+AR integrated extract, 30 mg/kg), and (9) OVX+IAT2 (TFG+AR integrated extract, 60 mg/kg). On the 8th day of treatment, tail and skin temperatures were recorded every 30 min for 24 h. Ovariectomized rats exhibited menopausal symptoms, such as hormonal imbalances and elevated skin temperature. Administration of AR, TFG, and IAT significantly decreased serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), and cortisol while increasing estradiol, progesterone, and dopamine (p < 0.0001), effectively alleviating hot flash-like symptoms. Additionally, they mitigated ovariectomy-induced oxidative stress by lowering malondialdehyde (MDA) levels and restoring antioxidant enzyme activity. Ovariectomized rats exhibited increased expression of a proto-oncogene (c-FOS), gonadotropin-releasing hormone (GnRH), Kisspeptin, Neurokinin B (NKB), and Transient receptor potential vanilloid 1 (TRPV1), along with reduced expressing brain-derived neurotrophic factor (BDNF) levels, which were reversed by treatment, especially with the IAT2 combination. The AR and TFG combination, particularly in IAT formulations, showed strong potential in alleviating menopausal symptoms in ovariectomized rats. These findings suggest that the combination of AR and TFG extracts could be a natural alternative for managing postmenopausal symptoms by restoring reproductive hormone levels, regulating lipid profiles, and enhancing antioxidant defense systems.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus8WoS8OpenAlex6
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2025Scopus SJRQ1
    Psychological effects of the COVID-19 pandemic on primary healthcare professionals in Turkey: One year into the pandemic

    Yücel, Ummahan; Erkal Aksoy, Yasemin; Yaşar Yetişmiş, Habibe; Gök, Çiğdem

    Aim and Objectives: This study aimed to determine the psychological effects of the COVID-19 pandemic on healthcare professionals working in primary care settings in the first year of the pandemic. Background: The healthcare industry has faced an unprecedented burden in the COVID-19 pandemic. Primary care professionals experienced the high level of psychological problems. Design and Methods: A total of 793 healthcare professionals from different regions of Turkey participated in this cross-sectional study. The STROBE (Strengthening the reporting of observational studies in epidemiology) checklist was used in the study. Data were collected online. Results: It has been found that more than half of healthcare professionals experienced severe depression, three-quarters experienced anxiety, and almost half experienced stress. It was also found that about half of the participants experienced a high degree of acute and chronic fatigue, and one-fifth experienced low inter-shift recovery. Conclusion: The effects of the COVID-19 pandemic on the mental health of primary care professionals, especially nurses and midwives, are alarming. The problems that arise from the flawed healthcare delivery models and gender inequality, which worsen the usual psychological effects of the pandemic on primary care professionals, should be addressed urgently. Relevance to Clinical Practice: Psychological support and rehabilitative services should be expanded to eliminate the short- and long-term psychological effects of the pandemic on healthcare professionals.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    • SDG 8 · İnsana Yakışır İş ve Ekonomik Büyüme
    AtıfScopus1WoS1OpenAlex1
    ScopusWeb of SciencePubMedİncele
  • Derleme MakaleAçık Erişim2025Scopus SJRQ2
    Ghrelin and LEAP2: Their Interaction Effect on Appetite Regulation and the Alterations in Their Levels Following Bariatric Surgery

    Alic, Nese; Ayaz, Aylin

    Background and Objectives: Ghrelin plays key roles in appetite regulation, involving both homeostatic and hedonic pathways. In obesity, its metabolism is affected by alterations in neural and hormonal responses. Liver-Enriched Antimicrobial Peptide 2 (LEAP2), recently identified as an endogenous ghrelin receptor antagonist, has emerged as a potential regulator of appetite and energy balance, and bariatric surgery is known to induce changes in this system. In this review, we aimed to evaluate the roles of acyl ghrelin, des-acyl ghrelin, and LEAP2 in food intake regulation and summarize findings on the alterations in their levels after bariatric surgery. Materials and Methods: We conducted a narrative review of human and animal studies published in the literature investigating the roles of acyl ghrelin, des-acyl ghrelin, and LEAP2 in food intake regulation, as well as changes in their levels in obesity and following bariatric surgery. Results: Alterations in the ghrelin system, i.e., the acyl ghrelin and des-acyl ghrelin isoforms and LEAP2, in obesity have been reported. Experimental studies have shown that LEAP2 administration reduces food intake and body weight by suppressing ghrelin-induced food intake. Most studies have found marked reductions in fasting acyl ghrelin after sleeve gastrectomy, more so than after Roux-en-Y gastric bypass. Conclusions: In obesity, altered neural and hormonal responses to food also affect ghrelin metabolism, with significant deviations in acyl ghrelin levels and impaired appetite regulation mechanisms. Unlike ghrelin, LEAP2 levels tend to be elevated in obesity. While changes in acyl ghrelin and des-acyl ghrelin isoforms, particularly after sleeve gastrectomy, are well documented, data on LEAP2 remain limited. Further research is needed to better define the role of LEAP2 in ghrelin-mediated food intake and its potential as a therapeutic target in obesity.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus6WoS5OpenAlex7
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2025Scopus SJRQ1
    Validation and adaptation of a Turkish version of the dietarian identity questionnaire

    Gumus, Damla; Macit, Arife; Demirci, Senol; Kizil, Mevlude

    Dietarian identity reflects an individual’s cognitive, emotional, and behavioral orientation toward the consumption or avoidance of animal-based foods, including red meat, poultry, fish, eggs, and dairy. This study aimed to adapt and validate the Dietarian Identity Questionnaire (DIQ) for Turkish-speaking populations by establishing its cultural and linguistic suitability and examining dietarian identity profiles among different dietary patterns. The DIQ was adapted into Turkish and administered via a webbased survey to 487 Turkish-speaking adults (Mean age=28.9±10.7 years; 34.7% male, 64.1% female, and 1.2% non-binary). Participants were categorized as omnivores, vegetarians, or vegans based on self-reported dietary exclusions. Structural validity was assessed using Confirmatory Factor Analysis, while internal consistency, composite reliability, and convergent and discriminant validity were evaluated through Cronbach’s alpha and average variance extracted. Group differences across dietary identity profiles were examined using ANOVA, and interrelationships among the DIQ-Turkish (DIQ-T) subscales were explored through Pearson correlation analysis. The results indicated that the eight-factor DIQ-T demonstrated a strong model fit (χ2 (465) =1841.45, p<0.001, CFI=0.924, TLI=0.914, RMSEA=0.078, SRMR=0.050), confirming its structural validity. Reliability analysis indicated high internal consistency across all subscales, and significant differences were observed between omnivores and vegan/vegetarian groups across multiple dimensions (p<0.001), highlighting distinct psychological and motivational patterns associated with dietarian identity. These findings support DIQ-T as a valid and reliable instrument for assessing dietarian identity, providing a valuable tool for researchers and health professionals investigating dietary behaviors and their potential implications for public health and nutrition interventions.

    • SDG 2 · Açlığa Son
    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2025Scopus SJRQ1
    Evaluation of aerobic and anaerobic capacity in pubertal karate athletes: performance analysis and development strategies

    Korkmaz, Kübranur; Aygören, Caner; Düzova, Halil

    Background: This study investigated the effects of gender’s foot arch structure (normal arch vs. pes planus) on aerobic and anaerobic performance in pubertal karate athletes. Method: Children with chronic cardiovascular and musculoskeletal diseases were excluded from the study. Participants included boys with normal foot arches (B-nfa, n = 7), boys with pes planus (B-pp, n = 11), girls with normal foot arches (G-nfa, n = 16), and girls with pes planus (G-pp, n = 11). Aerobic capacity was evaluated using the 6-Minute Walk Test, while anaerobic performance was assessed through the Vertical Jump Test and sprint tests (10 m and 30 m). The height of the foot arch was measured using the Navicular Drop test. Nonparametric data were analyzed using the Kruskal–Wallis test and Dunn's post-hoc test to identify significant differences. Parametric data were analyzed using one-way ANOVA and Tukey's post hoc test. Pearson's test was used for parametric correlation, while Spearman's test was used for nonparametric correlation. The significance threshold was set at p < 0.05. Results: Individuals in the G-nfa group exhibited higher anaerobic power than those in the G-pp group (p = 0.0452). There was a strong negative correlation between arch pes planus and Spear equations (r = 0.63, p = 0.0004). B-nfa participants performed faster than both B-pp (p = 0.0015) and G-pp (p = 0.0015). The G-nfa completed the 10 m sprint test faster than both B-pp and G-pp (p = 0.0052). B-nfa outperformed G-pp in the 30 m sprint (p = 0.036) and covered greater distances in the six-minute walk test compared to B-pp (p = 0.034) and G-pp (p = 0.002). Conclusion: In this study, we concluded that flat feet do not negatively affect the development of aerobic capacity in prepubertal children undergoing professional karate training. Still, they may significantly impact the growth of anaerobic power.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2025Scopus SJRQ1
    The effect of nursing services management efficiency on nurses’ professional commitment: A cross-sectional study

    Arslan Seker, Sevda; Coskun Palaz, Simge

    Aim: To determine the effect of nurses' perceptions of the effectiveness of nursing services management on their professional commitment. Background: Effective healthcare management is crucial for improving patient care quality. Understanding nurses' perspectives on nursing services management and their commitment provides valuable insights for management strategies, improving well-being and healthcare outcomes. Methods: This descriptive, cross-sectional, and correlational study involved 265 state hospital nurses. Data were collected between November 2020 and June 2021 using descriptive characteristic form, Nursing Services Management Effectiveness Scale, and Nursing Professional Commitment Scale. This study adhered to the STROBE checklist. Results: Nurses' views on the effectiveness of nursing services management and their professional commitment were found to be influenced by age, professional experience, and institutional positions. The average scores for nursing services management perception and professional commitment were 2.65 ± 0.72 and 66.63 ± 12.40, respectively. A statistically significant positive and low-level correlation was observed between nurses' nursing services management perception and professional commitment scores. Nurses' positive perception of nursing services management explains 17.1% of the variance in nurses' professional commitment levels. Discussion and conclusion: This study outlines how nurses' views on effective nursing services management can enhance their professional commitment. Managers should contribute to increase nursing services management efficacy by eliminating deficiencies in management practices to make their institutions successful and to increase their employees’ professional commitment level. Implications for nursing and health policy: Assuming positive perceptions of nursing management increase nurses' professional commitment, developing policies to boost organizational support is vital. Managers should focus on improving nursing services management to increase organizational success, increase nurses' professional commitment, and achieve the best health outcomes by eliminating management deficiencies.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfOpenAlex2
    ScopusWeb of SciencePubMedİncele
  • MakaleYayıncıda açık erişim2025Scopus SJRQ1
    Effectiveness of flipped classroom model in distance education: An experimental study in Turkish language course

    Aslan, Seda Aktı; Turgut, Yigit Emrah; Ünlü, Gökhan; Allison, Jordan

    This study investigates the impact of the Flipped Classroom Model (FCM) on university students’ learning achievement, self-directed learning skills (SLS), and course interaction within the context of live online classes (LOC). Employing a 14-week quasi-experimental design, the research involved an experimental group (n = 34) exposed to the FCM and a control group (n = 25) taught through traditional methods. Pre-tests indicated that the groups were not statistically different at baseline. Post-intervention analyses revealed no statistically significant differences between the groups in terms of immediate learning achievement or course interaction. However, results from a delayed post-test indicated that students in the experimental group demonstrated significantly higher retention of learning content compared to their counterparts. No significant improvements were observed in self-directed learning skills, suggesting that the FCM, as implemented, may not effectively foster such competencies across all learners. Furthermore, the model did not significantly enhance student interaction in the online classroom environment. These findings suggest that while the FCM may support long-term retention, its overall impact on achievement, interaction, and the development of SLS in LOC settings is limited and may be moderated by students’ existing self-regulatory capacities.

    • SDG 4 · Nitelikli Eğitim
  • MakaleYalnız künye2025Scopus SJRQ1
    Using Camelina Seed Mucilage as a Fat Replacer in the Production of Cookies and Its Effect on Physicochemical and Technological Properties

    Ozcan, Yasemin; Ozdemir-Orhan, Necla; Eroglu, Zeynep; Yilmaz, Merve Silanur

    In this study, for the first time, camelina (Camelina sativa (L.) Crtz.) seed mucilage (CM) was used as a fat substitute in a cookie formula, and the physicochemical, textural, and functional properties of mucilage-incorporated cookies were investigated. The moisture, protein, ash, fat, and carbohydrate content of the CM was 6.46% ± 0.35%, 17.44% ± 0.62%, 11.49% ± 0.39%, 1.27% ± 0.10%, and 63.16% ± 0.58%, respectively. Fourier transform infrared (FTIR) spectroscopy identified acidic (–COOH) functional groups in the CM. Four distinct cookie samples were examined: The control-cookie, 20% CM-cookie, 40% CM-cookie, and 60% CM-cookie were prepared by replacing shortening with CM at 0%, 20%, 40%, and 60% levels, respectively. The mucilage-incorporated doughs were softer, springy, cohesive, and resilient compared to the control dough (p < 0.05). As for the cookies, the fat content of the 20% CM-cookie, 40% CM-cookie, and 60% CM-cookie samples decreased by 12.52%, 31.49%, and 50.12%, respectively, compared to the control-cookie. The control-cookie had the lowest baking loss (p < 0.05), and the baking loss values of the mucilage-incorporated cookies increased with increasing fat replacement level. The highest spread ratio was recorded in the 20% CM-cookie, followed by the control-cookie (p < 0.05). The highest hardness and brittleness values (70.68 ± 3.37 N and 11.52 ± 0.34 mm) belonged to the 60% CM-cookie, whereas the lowest (19.42 ± 1.42 N and 8.80 ± 0.26 mm) belonged to the control-cookie (p < 0.05). Incorporating mucilage into the cookie formula increased the total phenolic compound content but decreased the antioxidant activity. These results show that CM has potential utility as a fat substitute in cookie production without significant quality loss.

    • SDG 2 · Açlığa Son
    AtıfScopus3WoS2OpenAlex3
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2025Scopus SJRQ2
    Associations Between Pulmonary Function and Muscle Strength in Turkish National Karate Athletes

    Tokgoz, Gurkan; Cinarli, Sena; Akyol, Betül; Aygoren, Caner; Beykumul, Aysegul; Larsen, Malte Nejst; Krustrup, Peter; França, Cíntia; Gouveia, Élvio Rúbio; Cinarli, Fahri Safa

    Background: Respiratory efficiency is considered important in karate due to its role in sustaining muscular performance during high-intensity actions. This study examined the association between pulmonary function and isometric muscle strength in national-level karate athletes. Methods: A total of 23 elite karate athletes (mean age: 23.0 ± 2.3 (mean ± SD) years) participated in the study. Pulmonary function was assessed using a digital spirometer, while isometric handgrip, lower back, and leg strength were measured using a dynamometer. The correlation between pulmonary function and isometric strength was analyzed, and linear regression was employed to examine the predictive capacity of pulmonary parameters for muscle strength. Results: The results revealed significant correlations, ranging from large to very large, between pulmonary function and isometric muscle strength, with correlation coefficients from 0.639 to 0.812 (p < 0.01). Pulmonary function was strongly associated with isometric strength, accounting for 27% to 67% of the variance (p < 0.05). Multiple regression analysis revealed that pulmonary function parameters accounted for 71% of the variance in handgrip strength, 47% in leg strength, and 71% in back strength (p < 0.05). Conclusions: These findings highlight the strong associations between pulmonary function and isometric muscle strength in elite karate athletes. The results emphasize the importance of pulmonary health and respiratory muscle function in athletic performance, particularly for sports requiring high-intensity, dynamic movements like karate. Future longitudinal studies are needed to explore the mechanisms underlying the association and potential implications, and for training and performance optimization.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2025Scopus SJRQ1
    Quality preservation of jujube fruit during cold storage: effect of maturity stage and modified atmosphere packaging

    Gun, Sefa; Ozturk, Burhan; Aglar, Erdal; Karakaya, Orhan

    Bacground: This study, which examines the effect between the maturity stage and modified atmosphere packaging (MAP) in order to prevent post-harvest quality losses and extend the storage life of jujube (Ziziphus jujuba Mill.) fruit, offers an important contribution to supply chain management. The fruits harvested at different maturity stages were stored at 0 ± 0.5 °C and 90 ± 5 RH in MAP and control conditions for 42 d and changes in quality, physiological and biochemical parameters were evaluated. Results: The lowest value was recorded in the early maturity (M-1) + MAP group for weight loss. Respiration rate decreased with advancing maturity, MAP treatments slowed down this process. Oxygen consumption and CO₂ production changed according to maturity level, MAP applications balanced gas exchange. MAP maintained brightness and color intensity of the fruit better. It also slowed down the firmness loss. The highest soluble solid content (SSC) was determined in the late maturity (M-3) + MAP group. Titratable acidity (TA) showed lower increase in MAP treatments. MAP significantly reduced the losses of vitamin C. Total phenolic, total flavonoids and antioxidant activity decreased during storage, while MAP treatments limited this decrease. Conclusions: The findings revealed that packaging jujube fruit with MAP, especially in early and mid-maturity stages, better preserves its quality parameters. Accordingly, MAP applications appropriate to the ripeness stage are recommended as an effective strategy to extend the fresh consumption period of jujube fruit and preserve its bioactive compounds.

    • SDG 2 · Açlığa Son
    AtıfScopus6WoS5OpenAlex5
    ScopusWeb of SciencePubMedİncele
  • MakaleYalnız künye2024Scopus SJRQ1
    Nutrification and fat reduction of deep-fried protein isolates

    Erol, Nida Demirtas; Cakli, Sukran; Szymczak, Mariusz; Shen, Cangliang; Matak, Kristen E.; Jaczynski, Jacek

    Deep-fried (DF) foods are considered nutritionally-inferior due to increased fat content, although they are popular with consumers due to desirable sensory characteristics. This study attempted to reduce fat of DF surimi, DF fish-protein-isolate (FPI), and DF chicken-protein-isolate (CPI) by pre-baking or pre-roasting. Surimi, FPI, and CPI were also nutrified with ω-3-rich oil, fiber, and KCl-based salt substitute. Pre-baking decreased (p < 0.05) fat content, while pre-roasting increased (p < 0.05) it. Pre-baking resulted in less (p < 0.05) changes to cook loss, moisture loss, expressible moisture, water-holding-capacity, whiteness, and texture when compared to pre-roasting. Pre-baking also better maintained ω-3 PUFAs concentration than pre-roasting, resulting in higher (p < 0.05) concentration of α-linolenic (ALA, 18:3ω3), eicosapentaenoic (EPA, 20:5ω3), and docosahexaenoic (DHA, 22:6ω3) FAs as well as unsaturated FAs and total ω-3 FAs in DF surimi, DF FPI, and DF CPI. Pre-baking in combination with nutrification using ω-3 PUFAs improved nutritional value of DF foods, while causing minimal quality changes.

    • SDG 2 · Açlığa Son
    AtıfScopus3WoS3OpenAlex3
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2024Scopus SJRQ2
    Is Cladophora fracta an efficient tool of accumulating critical raw materials from wastewater and there a potential health risk of use of algae as organic fertilizer?

    Arslan Topal, E. Işıl; Öbek, Erdal; Topal, Murat

    In this study investigation of accumulations of critical raw materials (cobalt (Co), antimony (Sb), vanadium (V), lanthanum (La) and tungsten (W)) from wastewater by using C. fracta were aimed. Besides, assessment of the potential health risks in terms of the use of organic fertilizer obtained from the macroalga to be harvested from the treatment were also aimed. Highest Co, Sb, V, La and W accumulations by algae in reactor were 125±6.2%, 201.25±10%, 318.18±15%, 357.97±18%, and 500±25%, respectively. When compared with control, Co, Sb, V, La and W in algae increased 2.25, 3.01, 4.18, 4.58, and 6 times, respectively. The algae was very high bioaccumulative for Co and La. Highest MPI was calculated as 3.94. Non-carcinogenic risk of CRMs according to different exposure types (ingestion, inhalation, and dermal) were calculated for man, woman and child. There is not any non-carcinogenic risk from the investigated exposure ways of algae as organic fertilizer.

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus2WoS2OpenAlex2
    ScopusWeb of SciencePubMedİncele
  • MakaleYalnız künye2024Scopus SJRQ2
    Synthesis and characterization of TiNbZrMo medium-entropy bio-composites: Microstructure, mechanical properties, and in vitro degradation

    Say, Yakup

    This study reports the synthesis and characterization of hydroxyapatite (HA)-based bio-composites reinforced with varying amounts (by weight, 1–15 wt.%) of bio-medium entropy alloy (BioMEA) for load-bearing implant applications. BioMEA powders consisting of Ti, Nb, Zr, and Mo were mechanically alloyed for 100 h and subsequently added to HA using powder metallurgy techniques. To show the effect of BioMEA, the microstructure, density, and mechanical tests have been conducted and the synthesized BioMEA was characterized by scanning electron microscope (SEM), x-ray diffractometer (XRD), and Fourier-transform infrared spectroscopy (FTIR) analysis. In addition, in vitro degradation behavior and bioactivity analyses of bio-composites have been conducted. XRD analysis revealed the formation of BioMEA after 20 h of mechanical alloying. The highest density value of 2.47 g/cm3 was found in 15 wt.% BioMEA-reinforced bio-composite. The addition of BioMEA reinforcement led to a significant increase in hardness and tensile strength values, with the highest values observed at 15 wt.% reinforcement. Compression tests demonstrated a significant increase in compressive strength and deformation capability of the bio-composites with the highest values observed at 15 wt.% BioMEA addition. The highest toughness of 7.68 kJ/m2 was measured in 10 wt.% MEA-reinforced bio-composites. The produced bio-composite materials have an elastic modulus between 3.5–5.5 GPa, which may provide a solution to the stress shielding problems caused by the high elastic modulus of metallic implant materials. The most severe degradation occurred in 15 wt.% MEA-reinforced bio-composites, and the effect of degradation caused a decrease in Ca and an increase in Ti-Ni-Zr-Mo in all bio-composites. These findings suggest that HA/BioMEA bio-composites have the potential to be developed as advanced biomaterials with moderate mechanical and biological properties for load-bearing implant applications.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus2WoS1OpenAlex3
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2024Scopus SJRQ2
    Genotypic diversity and antagonistic activities of enterococci isolated from pastırma

    Ertekin, Özlem; Kaban, Güzin; Kaya, Mükerrem

    The biodiversity of enterococci from pastırma (a traditional Turkish dry-cured meat product) by genotypic identification and the antagonistic activities of strains were investigated. Pastırma samples taken from 20 different small-scale factories were subjected to microbiological and physicochemical analysis. A hundred enterococci isolates were identified by 16S rRNA gene sequence analysis. To determine antagonistic activity of strains, Listeria monocytogenes and Staphylococcus aureus were used. The lactic acid bacteria and Micrococcus/Staphylococcus counts were ≥ 6 log cfu/g in 55% of the samples and 75% of the samples, respectively. Enterobacteriaceae was generally below the detectable level (< 2 log cfu/g). The enterococci count was higher than 6 log cfu/g in 30–35% of the samples, depending on the medium used. The enterococci isolates (100 isolates) were identified as E. faecium (80 strains), E. faecalis (19 strains) and E. hirae (1 strain) in genotypic identification. The nine E. faecium strains showed antagonistic activity against L. monocytogenes in the well diffusion test. In contrast, in the same antagonistic activity test, all of the strains had no antagonistic activity against S. aureus. Further studies could be planned to characterize E. faecium strains that show antagonistic activity against L. monocytogenes.

    • SDG 2 · Açlığa Son
    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus2WoS2OpenAlex1
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2024Scopus SJRQ1
    Ensemble Learning Framework for DDoS Detection in SDN-Based SCADA Systems

    Oyucu, Saadin; Polat, Onur; Türkoğlu, Muammer; Polat, Hüseyin; Aksöz, Ahmet; Ağdaş, Mehmet Tevfik

    Supervisory Control and Data Acquisition (SCADA) systems play a crucial role in overseeing and controlling renewable energy sources like solar, wind, hydro, and geothermal resources. Nevertheless, with the expansion of conventional SCADA network infrastructures, there arise significant challenges in managing and scaling due to increased size, complexity, and device diversity. Using Software Defined Networking (SDN) technology in traditional SCADA network infrastructure offers management, scaling and flexibility benefits. However, as the integration of SDN-based SCADA systems with modern technologies such as the Internet of Things, cloud computing, and big data analytics increases, cybersecurity becomes a major concern for these systems. Therefore, cyber-physical energy systems (CPES) should be considered together with all energy systems. One of the most dangerous types of cyber-attacks against SDN-based SCADA systems is Distributed Denial of Service (DDoS) attacks. DDoS attacks disrupt the management of energy resources, causing service interruptions and increasing operational costs. Therefore, the first step to protect against DDoS attacks in SDN-based SCADA systems is to develop an effective intrusion detection system. This paper proposes a Decision Tree-based Ensemble Learning technique to detect DDoS attacks in SDN-based SCADA systems by accurately distinguishing between normal and DDoS attack traffic. For training and testing the ensemble learning models, normal and DDoS attack traffic data are obtained over a specific simulated experimental network topology. Techniques based on feature selection and hyperparameter tuning are used to optimize the performance of the decision tree ensemble models. Experimental results show that feature selection, combination of different decision tree ensemble models, and hyperparameter tuning can lead to a more accurate machine learning model with better performance detecting DDoS attacks against SDN-based SCADA systems.

    • SDG 7 · Erişilebilir ve Temiz Enerji
    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
    AtıfScopus36OpenAlex27
    ScopusWeb of SciencePubMedİncele
  • MakaleYalnız künye2024Scopus SJRQ1
    The effects of listening to lullabies and self-selected music at home on prenatal stress and anxiety in nulliparous pregnant women: A randomized-controlled study

    Baltacı, Nazlı; Doğan Yüksekol, Özlem; Koç, Emine; Ulucan, Mihriban

    To compare the effects of nulliparous pregnant women listening to lullabies and self-selected music on reducing the anxiety and antenatal stress. This was a randomized controlled study. Lullaby group (LG) (n = 40) listened to the lullaby chosen by the researcher, mixed music group (MG) (n = 40) listened to self-selected music and control group (CG) (n = 40) received general care. Post-test anxiety and stress levels was lower in two intervention groups versus CG (p < 0.01). Post-test anxiety was lower in the MG versus LG (p < 0.01), however post-test stress levels were similar. Pregnant women listening to self-selected music at home is more effective in reducing anxiety.

    AtıfScopus6WoS7
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2024Scopus SJRQ3
    Exploring Sorbus torminalis Leaves: Unveiling a Promising Natural Resource for Diverse Chemical and Biological Applications

    Ak, Gunes; Tüfekci, Enis Fuat; Mustafa, Ahmed M.; Caprioli, Giovanni; Altunoglu, Yasemin Celik; Baloglu, Mehmet Cengiz; Cakılcıoglu, Ugur; Polat, Rıdvan; Darendelioglu, Ekrem; Zengin, Gokhan

    Sorbus torminalis (L.) Crantz has a rich history of versatile applications spanning the fields of medicine and nutrition. It is noteworthy that the decoction obtained from S. torminalis leaves is a traditional treatment method against both diabetes and stomach disorders. Phytochemical profiling determined by HPLC/MS-MS. The effects of the extracts on cell viability were investigated using the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) method against MDA-MB-231 cell line (human breast adenocarcinoma).The ethanol/water extract contained more concentration of total phenolic (91.41 mg gallic acid (GAE) equivalent /gr) and flavanoid (29.10 mg rutin (RE) equivalent/gr) in the tested extract (p<0.05). Resulting of HPLC analysis, the chemical constituents varied depending on the solvents and chlorogenic acid, hyperoside, isoquercetin, delphindin-3,5-diglucoside, procyanidin B2, epicatechin, neochlorogenic acid, 3,5-dicaffeoylquinic acid were identified in all extracts. Overall, ethanol, n-hexane and ethyl acetate extracts showed the highest inhibition for the tyrosinase enzyme. The effect of leaf extracts of S. torminalis on antimicrobial, biofilm inhibitory, and anticancer activities was examined. Based on outcomes of our study recognize this plant as a critical source of medically active chemicals for feasible phytopharmaceutical and nutraceutical applications, providing the first scientific insight into the detailed biological and chemical profiles of S. torminalis.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus7OpenAlex5
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2024Scopus SJRQ2
    Leachate treatment via electrocoagulation–coal-based powdered activated carbon process: Efficiencies, mechanisms, kinetics, and costs

    Ogedey, Aysenur; Oguz, Ensar

    This study aims to improve COD, NH3-N, and turbidity removal from Bingöl's leachate using a single-reactor integrated electrocoagulation (EC)–coal-based powdered activated carbon (CBPAC) process under various experimental conditions. In the EC-CBPAC process, three stainless-steel cathodes and three aluminum electrodes were connected to the negative and positive terminals of the power supply, respectively. The initial concentrations in the leachate were 1044 mg O2/L for COD, 204 mg/L for NH3-N, and 57 NTU (or 71.25-mg (NH2)2H2SO4/L) for turbidity, respectively. After a 40-min EC-CBPAC process, with a CBPAC dosage of 5 g/L and pH of 5 for COD and turbidity, and 9.5 for NH3-N, the optimum removal efficiencies for COD, NH3-N, and turbidity were achieved at 92%, 40%, and 91%, respectively. When the EC process was applied without CBPAC under the same experimental conditions, the removal efficiencies of COD, NH3-N, and turbidity were 87%, 28%, and 54%, respectively. Before and after the EC-CBPAC process, the Brunauer–Emmett–Teller (BET) surface area, pore volume, and mean pore diameter of the CBPAC were found to be (888 m2/g, 0.498 cm3/g, and 22.28 Å) and (173 m2/g, 0.18 cm3/g, and 42.8 Å), respectively. The optimum pseudo-first-order (PFO) rate constants for COD, turbidity, and NH3-N were determined to be 3.15 × 10−2, 4.77 × 10−2, and 8.8 × 10−3 min−1, respectively. With the current density increasing from 15 to 25 mA/cm2, energy consumption, unit energy consumption, and total cost increased from 68.7 to 122.4 kWh/m3, 6.948 to 15.226 kWh/kg COD, and 0.85 to 1.838 $/kg COD, respectively. Practitioner points: EC-CBPAC process has greater COD, NH3-N, and turbidity removal efficiency than EC process. COD and turbidity achieved their optimum disposal efficiencies at 92% and 91%, respectively, at pH 5 The most efficient disposal efficiency for NH3-N was observed to be 40% at pH 9.5. EC-CBPAC process increased removal efficiencies for COD, NH3-N, and turbidity by 20%, 19%, and 38%, respectively, compared with EC alone. The turbidity, NH3-N, and COD disposal fitted PSO model due to high correlation values (R2 0.94–0.99).

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus3WoS3OpenAlex3
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2024Scopus SJRQ1
    Work stress and obsessive-compulsive symptoms in nurses and office workers: a comparative study

    Kuzu Durmaz, Ayşe; Çiçekoğlu Öztürk, Pınar; Çevik Durmaz, Yadigar

    Objectives. This study aims to compare the work stress and obsessive-compulsive symptoms of nurses and office workers and to determine the relationship between work stress and obsessive-compulsive symptoms. Methods. A total of 127 nurses and 127 office workers participated in the cross-sectional study and comparative study. Data were collected using the perceived work stress scale and the Maudsley obsessive-compulsive inventory. Results. Nurses had higher work stress scores (p = 0.003) in general than office workers. In particular, nurses with a low (p < 0.039) and average (p < 0.007) economic status, nurses who had been employed for 1–10 years (p < 0.001) and nurses working 40 h per week (p < 0.042) had higher work stress scores than office workers. There was no difference (p > 0.05) between obsessive-compulsive symptom scores. There was a positive significant relationship (p < 0.001) between work stress and obsessive-compulsive symptom scores of nurses and office workers. Work stress explains 6.1% of the obsessive-compulsive symptoms in nurses and 12.4% in office workers. Conclusion. The results of this study concluded that work stress of nurses is higher than that of office workers and work stress affects the obsessive-compulsive symptoms in both groups.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    • SDG 8 · İnsana Yakışır İş ve Ekonomik Büyüme
    AtıfScopus4WoS3OpenAlex3
    ScopusWeb of SciencePubMedİncele