Yazarlar
- Gul, Muhammet(35)
- Erten, Fusun(23)
- Zengin, Gokhan(23)
- Benzer, Fulya(22)
- Dal, Nursel Alp(20)
- Sahin, Kazim(20)
- Orhan, Cemal(19)
- Yeşiltepe, Akgün(17)
- Topal, Murat(15)
- Yucesan, Melih(15)
- Yildirim, Ozal(13)
- Öbek, Erdal(13)
- Aksakal, B.(12)
- Gürarslan Baş, Nazan(12)
- Alp Dal, Nursel(11)
- Baloglu, Ulas Baran(11)
- Cakilcioglu, Ugur(11)
- Kandemir, Fatih Mehmet(11)
- Paksoy, Mehmet Yavuz(11)
- Talo, Muhammed(11)
- Celik, Erkan(10)
- Er, Besir(10)
- Say, Yakup(10)
- Yaman, Mine(10)
- Yüksekol, Özlem Doğan(10)
- Aksu, Önder(9)
- Aslan, N.(9)
- Aslan, Naim(9)
- Baş, Kazım(9)
- Erişir, Mine(9)
- Mahomoodally, Mohamad Fawzi(9)
- Acharya, U. Rajendra(8)
- Caprioli, Giovanni(8)
- Karatay, Gülnaz(8)
- Kocabaş, Mehmet(8)
- Macit, Arife(8)
- Parlak Ak, Tuba(8)
- İpek, Yeliz(8)
- Beydağ, Kerime Derya(7)
- Camas, Mustafa(7)
Yayınlar
- MakaleAçık Erişim2021Scopus SJRQ1Magnesium picolinate improves bone formation by regulation of rank/rankl/opg and bmp-2/runx2 signaling pathways in high-fat fed rats
Sahin, Emre; Orhan, Cemal; Balci, Tansel Ansal; Erten, Fusun; Sahin, Kazim
Magnesium (Mg) deficiency may affect bone metabolism by increasing osteoclasts, de-creasing osteoblasts, promoting inflammation/oxidative stress, and result in subsequent bone loss. The objective of the present study was to identify the molecular mechanism underlying the bone protective effect of different forms of Mg (inorganic magnesium oxide (MgO) versus organic magnesium picolinate (MgPic) compound) in rats fed with a high-fat diet (HFD). Forty-two Wistar albino male rats were divided into six group (n = 7): (i) control, (ii) MgO, (iii) MgPic, (iv) HFD, (v) HFD + MgO, and (vi) HFD + MgPic. Bone mineral density (BMD) increased in the Mg supplemented groups, especially MgPic, as compared with the HFD group (p < 0.001). As compared with the HFD + MgO group, the HFD + MgPic group had higher bone P (p < 0.05) and Mg levels (p < 0.001). In addition, as compared to MgO, MgPic improved bone formation by increasing the levels of osteo-genetic proteins (COL1A1 (p < 0.001), BMP2 (p < 0.001), Runx2 (p < 0.001), OPG (p < 0.05), and OCN (p < 0.001), IGF-1 (p < 0.001)), while prevented bone resorption by reducing the levels of RANK and RANKL (p < 0.001). In conclusion, the present data showed that the MgPic could increase osteogenic protein levels in bone more effectively than MgO, prevent bone loss, and contribute to bone formation in HFD rats.
AtıfScopus21WoS20OpenAlex21
İncele - MakaleYalnız künye2021Scopus SJRQ1Toxicological effects of di-(2-ethylhexyl) phthalate in Gammarus pulex: a biochemical and histopathological assessment
Yildirim, Nuran Cikcikoglu; Ak, Tuba Parlak; Samasas, Omer
This study aimed to reveal the toxic characteristics of di-(2-ethylhexyl) phthalate (DEHP) by examining the biochemical and histopathological changes in Gammarus pulex, exposed to different doses of DEHP. For this purpose, the lethal concentration 50 (LC50) value of the DEHP was determined by using a static test and found to be 0.079 ± 0.01 ppm. Three subletal doses of DEHP were applied to the G. pulex for 24 and 96 h. Superoxide dismutase (SOD), catalase (CAT), cytochrome P450 1A1 (CYP1A1), and glutathione S-transferase (GST) activities were measured using commercial ELISA kits. The caspase method, which is an immunohistochemical analysis method, was used to determine the apoptosis that occurred in the G. pulex. The results showed that the CYP1A1 activities decreased in the groups exposed to different doses of DEHP compared to the control group (p > 0.05). CAT activity was found to increase in the application groups at the 24 and 96 h compared to the control group. In addition, it was found that SOD and GST activities increased at the 96 h compared to the control group. In light of the microscope examination of the model organism, hemolymphatic lacunae filled with hemolymph and reduction or absence of hemolymphatic ducts were observed especially in the G. pulex gills. Collapse of the gills and hyperplasia were observed after 96 h. As a result, it is suggested that changes in SOD, CAT, and GST activities can potentially be used as sensitive biomarkers for risk assessment in the environment and increased immunoreactivity in G. pulex caused by DEHP depending on increased application doses and application times.
AtıfScopus6WoS3OpenAlex5İncele - MakaleYalnız künye2021Scopus SJRQ3Enhanced Adhesion and Corrosion Properties of Boron Doped Bioceramic Coated 316L Implants
Aksoy, M.E.; Aksakal, B.; Aslan, N.; Dikici, B.
Abstract: In order to provide an effective prevention to 316L implants, a synthesized bioceramic was coated by using electrophoretic deposition (EPD). The effect of boron addition into hydroxyapatite (HA) on surface morphology, adhesion and corrosion resistance of the implant has been examined. Boron doped HA (B–HA) was synthesized by a simple chemical acid-base method with 5, 10, and 15 wt % boron additions to coat on 316L implants. The synthesized B-HA was coated on the substrates and the coated surfaces with and without B additions. Sintering took place at different temperatures and sintering rates. The coatings were characterized by X-ray diffractometer (XRD), Fourier transform infrared spectroscopy (FT–IR) and scanning electron microscope (SEM). Furthermore, adhesion and in vitro corrosion tests were conducted. The influence of boron additons on adhesion and corrosion resistance of 316L have been revealed for the coated substrates at different B additions. It was shown that boron addition increased the adhesion and corrosion resistance of the bioceramic coatings. Furthermore, the sintering effect on adhesion was also evaluated and the highest adhesion as 25.8 MPa has been reached at 750°C for 90 s and 5°C min–1 sintering conditions. It was found that using iodine as EPD dispersant has increased the charging ability of the B–HA powders in the suspension and hence eased deposition rate. The study revealed that boron-containing hydroxyapatite coatings can provide crack-free surfaces that providing high adhesion and hence increase the corrosion resistance of metallic implants. Through the results, it was also shown that the network between powders was improved and hence adhesion was increased with increasing B addition.
AtıfScopus10WoS9OpenAlex12İncele - MakaleYalnız künye2021Scopus SJRQ4Reflections of nature-oriented outdoor sports activities on coronavirus-19 phobia during the pandemic process
Sandikç, Muhammed Bahadır; Önen, Cihan
Study Objectives: This study was carried out to evaluate the impact of participation in nature-oriented outdoor sports activities on Coronavirus-19 phobia during the pandemic process. Methods: The population of the cross-sectional study consists of 289 people who were engaged in nature-oriented outdoor sports activities in the Tunceli region between 28.06.2021 and 20.07.2021. Results: COVID-19 phobia was statistically higher in women, people under 35, singles, those with high school or lower education, and those who do not have children. Although many nature sports activities reduce the phobia of COVID-19, there was especially a statistically significant decrease in COVID-19 phobia among those who engage in rock climbing. Besides, those who practiced outdoor sports with fear of death and quarantine had a statistically higher COVID-19 phobia score. There was a weakly significant negative relationship between the years of experience, the number of types of outdoor sports activities that the individuals engage in, and the COVID-19 phobia score. As the years of experience in these activities and their types increased, the COVID-19 phobia decreased, albeit weakly. Conclusion: Performing nature-oriented outdoor sports activities from different fields can be beneficial, even partially, in reducing the phobia caused by COVID-19. In pandemics, such as COVID-19, which have a wide range of negative effects on society, individuals can be directed to nature sports against COVID-19 phobia.
AtıfOpenAlex1İncele - MakaleAçık Erişim2021Scopus SJRQ1Comprehensive biological and chemical evaluation of two seseli species (S. gummiferum and s. transcaucasicum)
Zengin, Gokhan; Stojković, Dejan; Mahomoodally, Mohamad Fawzi; Jugreet, Bibi Sharmeen; Paksoy, Mehmet Yavuz; Ivanov, Marija; Gašić, Uroš; Gallo, Monica; Montesano, Domenico
Seseli L. is one of the largest genera of the Apiaceae family widely known for their traditional uses as herbal remedies. In the present study, the methanolic and water extracts of two Seseli species, S. gummiferum and S. transcaucasicum were evaluated for their bioactive contents and biological activities. The total phenolic and flavonoid contents in the extracts ranged from 19.09 to 24.33 mg GAE/g and from 0.45 to10.09 mg RE/g, respectively. Moreover, while narcissin was detected as the most abundant component in the methanolic extract of S. transcaucasicum (261.40 µg/g), chlorogenic acid was identified as the major component in all the other extracts, although a high amount was also present in the methanolic S. transcaucasicum extract (107.48–243.12 µg/g). The total antioxidant capacity was also determined by the phosphomolybdenum assay (0.66–1.18 mM TE/g). Other antioxidant assays such as the radical scavenging assays (DPPH: 5.51–11.45 mg TE/g; ABTS: 43.46–51.91 mg TE/g), reducing assays (CUPRAC: 41.67–53.20 mg TE/g; FRAP: 31.26–34.14 mg TE/g), as well as the metal chelating activity assay (14.38–38.57 mg EDTAE/g) were conducted. All the extracts showed inhibitory potential against the enzyme’s amylase (0.12–0.78 mM ACAE/g), acetyl-and butyryl-cholinesterase (0.15–9.71 mg GALAE/g), while only the methanolic extracts acted as inhibitors of tyrosinase (107.15 and 109.37 mg KAE/g) and only the water extract of S. gummiferum displayed anti-glucosidase activity (0.13 mM ACAE/g). Interestingly, the methanolic extracts of both Seseli species showed lower cytotoxicity towards HaCaT cells (IC50: >500 µg/mL), compared to the water extracts (IC50: 267.8 and 321.41 µg/mL). Besides, only the methanolic extracts showed a slight wound healing effect (28.21 and 31.23%). All extracts showed antibacterial action against Staphylococcus lugdunensis (minimum inhibitory and bactericidal concentrations: 0.025–2 mg/mL). S. gummiferum methanolic extract, which exhibited the highest antibacterial potency was found to inhibit adhesion and invasion of S. lugdunensis to HaCaT cells as well. Taken together, this study demonstrated the two Seseli species to harbour interesting bioactive components, in particular polyphenolics and to exhibit several biological properties that could be further investigated for their potential exploitation as healing agents as supported by various traditional medicinal uses.
AtıfScopus16OpenAlex15İncele - Kitap BölümüYalnız künye2021A Risk Prioritization Method Based on Interval-Valued Pythagorean Fuzzy TOPSIS and Its Application for Prioritization of the Risks Emerged at Hospitals During the Covid-19 Pandemic
Gul, Muhammet; Yucesan, Melih
AtıfScopus2İncele - MakaleYalnız künye2021Scopus SJRQ2Boron-Doped Hydroxyapatite Coatings on NiTi Alloys Using the Electrophoretic Deposition Method: Enhanced Corrosion and Adhesion Performances
Aksoy, M.E.; Aksakal, B.; Aslan, N.; Dikici, B.
Metallic implants are functionalized with coatings due to the need to protect against biological corrosion in the body. Hydroxyapatite (HAp) has desirable biocompatibility and structural properties, but poor mechanical properties limit its use as a standalone coating. In this study, boron-doped hydroxyapatite (B-HAp) biocomposites containing 5, 10, and 15% boron by weight were synthesized by the sol-gel method and applied as a coating to NiTi using electrophoretic deposition (EPD). The deposition was carried out for 60, 90, and 120 s, and sintering at 750 °C for 75 minutes under vacuum. The coated substrates were then characterized by XRD, SEM, and FT-IR, and their adhesion strengths and in-vitro corrosion behaviors in simulated body fluid were compared with uncoated samples. The results showed that the microporous powders formed well-bonded structures, which positively affect adhesion strength. The highest adhesion strength (30 MPa) and corrosion resistance were achieved with 15 wt.% B-HAP coating at 120 s deposition time and 76.5 μm coating thickness.
AtıfScopus18WoS16OpenAlex19İncele - MakaleAçık Erişim2021Scopus SJRQ1Next‐generation ultrasol curcumin boosts muscle endurance and reduces muscle damage in treadmill‐exhausted rats
Sahin, Emre; Orhan, Cemal; Erten, Fusun; Er, Besir; Acharya, Manutosh; Morde, Abhijeet A.; Padigaru, Muralidhara; Sahin, Kazim
Curcumin positively affects performance during exercise and subsequent recovery. However, curcumin has limited bioavailability unless consumed in larger doses. In the current study, we examined the impact of a new formulation of curcumin, Next‐Generation Ultrasol Curcumin (NGUC), which is relatively more bioavailable than natural curcumin on exhaustion time, grip strength, muscle damage parameters, and serum and muscle proteins. A total of 28 rats were randomly grouped as control (C, non‐supplemented), exercise (E, non‐supplemented), E+NGUC100 (supplemented with 100 mg/kg BW NGUC), and E+NGUC200 (supplemented with 200 mg/kg NGUC). Grip strength and exhaustion time were increased with NGUC supplementation (p < 0.0001). Creatine kinase (CK), lactate dehydrogenase (LDH), lactic acid (LA), myoglobin, malondialdehyde (MDA) concentrations were reduced in serum, and muscle tissue in NGUC supplemented groups (p < 0.05). In contrast, NGUC supplementation elevated the antioxidant enzyme levels compared to the non‐supplemented exercise group (p < 0.01). Additionally, inflammatory cytokines were inhibited with NGUC administration (p < 0.05). NGUC decreased PGC‐1α, p‐4E‐BP1, p‐mTOR, MAFbx, and MuRF1 proteins in muscle tissue (p < 0.05). These results indicate that NGUC boosts exercise performance while reducing muscle damage by targeting antioxidant, anti‐inflammatory, and muscle mass regulatory pathways.
AtıfScopus9WoS9OpenAlex9İncele - MakaleAçık Erişim2021Scopus SJRQ1Investigation of perceived fear of COVID-19 and vaccine hesitancy in nursing students
Yeşiltepe, Akgün; Aslan, Sinan; Bulbuloglu, Semra
This study aims to investigate the perceived fear of COVID-19 and vaccine hesitancy in nursing students. This study was conducted as a cross-sectional study with the participation of 1167 nursing students. Personal Information Form, Vaccine Hesitancy Scale and Fear of COVID-19 Scale were used for data collection. The reasons for the vaccine hesitancy of the students were listed as follows: 57.6% of them stated that it had side effects, 17.7% stated there was no conclusive evidence that the vaccine was effective, and 12.6% stated it was not reliable. A positive correlation was found between fear of COVID-19 and vaccine hesitancy.
AtıfScopus19WoS19OpenAlex30İncele - MakaleAçık Erişim2021Scopus SJRQ3The protective effects of lupine (Lupinus albus) fruit extract against to destructive effects of hyperglycemia in type I diabetic rats
Aydın, Sevinç; Kaya, Tubay; Erman, Orhan; Yılmaz, Ökkeş
Background: Lupinus albus is a member of the Fabaceae family. As a natural or cultivat-ed plant, Lupinus albus is distributed in Europe, the Balkans and Turkey, especially in Marmara and Aegean regions. The lupine is a nutritious and protective plant against diabetes. Objective: In the present study, the effects of Lupinus albus fruits on malondialdehyde (MDA), reduced glutathione (GSH), total protein, ADEK vitamins, and cholesterol values, which are the indi-cators of oxidative damage and antioxidant defense. In this regard, muscle, liver, renal, and brain tissues of STZ-induced type I diabetes rats were studied. Methods: The analyzes of ADEK vitamins and cholesterol levels in tissues were performed via Shimadzu HPLC device. The lipid peroxidation levels were measured at 532 nm in spectrophotome-ter. Determination of GSH was read at 412 nm against blank, and for the total protein levels Lowry method was applied. Results: According to the results obtained, it was determined that among the rats with induced type I diabetes, the group applied lupine fruit extract was found to have increased GSH level and decreased MDA levels in all the tissues. The protein values were increased in liver tissues but decreased in the other tissues. The level of vitamins was significantly increased in almost all the tissues in the diabetic group. Conclusion: In the present study, it was shown that the lupine reduced the devastating effects of type I diabetes by decreasing the fasting blood glucose and lipid peroxidation values and increasing the glutathione level in comparison to the diabetic group.
AtıfScopus4WoS4OpenAlex4İncele - Kitap BölümüYalnız künye2021Fine–kinney-based occupational risk assessment using interval type-2 fuzzy qualiflex
Gul, Muhammet; Mete, Suleyman; Serin, Faruk; Celik, Erkan
In this chapter, we improved Fine–Kinney occupational risk assessment approach with interval type-2 fuzzy QUALIFLEX (IT2FQUALIFLEX). QUALIFLEX is an outranking multi-attribute decision-making method proposed by an extension of the Paelinck’s (Pap Reg Sci Assoc 36:59–74,[1]), generalized Jacquet-Lagreze’s permutation method. Similar to other outranking solution-based approaches, it considers the solution which is a comparison of hazards. In this chapter, we adapted the interval type-2 fuzzy sets (IT2FSs) into QUALIFLEX as it reflects the uncertainty well in decision-making. IT2FQUALIFLEX algorithm under the Fine–Kinney concept provides a useful and solid approach to the occupational health and safety risk assessment. In addition to proposing this new approach, a case study is performed in the chrome plating unit. A validation is also performed in this study. Finally, the proposed approach is implemented in Python.
AtıfScopus7OpenAlex7İncele - MakaleAçık Erişim2021Scopus SJRQ1The effect of ethnocentrism and moral sensitivity on intercultural sensitivity in nursing students, descriptive cross-sectional research study
Kaya, Yunus; Arslan, Sevda; Erbaş, Atiye; Yaşar, Beril Nisa; Küçükkelepçe, Gülhan Erkuş
Background: Factors affecting intercultural sensitivity and care are becoming an increasingly important issue due to ethnic diversity. Nurses play a crucial role in care and therefore should keep up with this trend and improve their intercultural sensitivity. Objective and design: This descriptive cross-sectional study investigated the effects of ethnocentrism and moral sensitivity on intercultural sensitivity in nursing students. Methods and participants: Data were collected using a demographic characteristics questionnaire and the Intercultural Sensitivity Scale, Generalized Ethnocentrism Scale, and Moral Sensitivity Scale. The sample consisted of 1343 nursing students. The Pearson correlation coefficient was used to determine correlations between scale scores. Multiple linear regression was used to determine the effects of ethnocentrism, moral sensitivity, and demographic characteristics on intercultural sensitivity. Results: Intercultural sensitivity was found to be negatively correlated with ethnocentrism and positively correlated with moral sensitivity. Ethnocentrism predicted intercultural sensitivity more than moral sensitivity. Ethnocentrism and moral sensitivity explained 16.8% of the total variance of intercultural sensitivity. However, ethnocentrism affected intercultural sensitivity more than moral sensitivity did (beta = −0.406). Conclusion: Nursing education should adopt strategies to reduce ethnocentrism by helping students develop cultural competence and intercultural sensitivity. Such education can equip nurses to provide higher quality care to patients of different cultural backgrounds.
AtıfScopus48OpenAlex54İncele - MakaleAçık Erişim2021Scopus SJRQ4Perceptions and experiences of older people regarding the covid-19 pandemic process: A phenomenological study
Akkuş, Yeliz; Parlak, Ayşe Gül; Karacan, Yasemin; Karatay, Gülnaz
Introduction: From the start of the coronavirus disease 2019 (COVID-19) outbreak in 2020 to the present, older people have been the worst affected among all age groups. This study was conducted to examine thoroughly the perceptions and experiences of older people regarding the COVID-19 outbreak. Materials and Methods: A qualitative study was conducted using a semi-structured, in-depth interview method with 16 older people living in the east of Turkey. The interviews were conducted through the mobile application WhatsApp, as the older people were in the risk group for infection. The sample group was reached using the snowball method. When the data obtained from the participants reached the saturation level, two more interviews were conducted, and then the interviews were ended. After the recorded interviews were transcribed, they were subjected to conventional content analysis. Results: Four main themes emerged from the interviews in line with the purpose of this study. These themes are The Meaning of COVID-19, Outcomes of COVID-19, Need for Support and Resources, and Attitudes toward Vaccination. Conclusion: It was determined that the older people experienced fear during the COVID-19 pandemic; the social restrictions affected them psychologically, physiologically, and economically and they could not get enough support and felt lonely in this process; but nevertheless, they were hopeful about the vaccine. To address these findings, this study suggested support for home care of older people and the development of psychosocial and economic support programs for them.
AtıfScopus2WoS3OpenAlex4TR Dizin1
İncele - MakaleAçık Erişim2021Scopus SJRQ2Investigation of the potential human health risk of toxic mercury determined in the grapevine exposed to mine gallery waters
Topal, Murat
In the present study, mercury was selected because of its toxicity. It was detected in the grapevines exposed to mine gallery waters. The potential health risk of mercury in leaves of grapevine those are consumed by human worldwide was investigated. The grapevines were harvested and separated into organs of roots, stems, and leaves. The concentrations of mercury were determined in roots, stems, and leaves. The translocation and bioconcentration factors were calculated. Maximum concentrations of mercury were stem < root < leaf. The health risk potential of mercury on human health was calculated. The estimated daily exposure doses of mercury followed an order for children and adults: dietary > ingestion > inhalation > dermal. The HQ values calculated for exposure ways of dietary, ingestion and inhalation were male < female < children. As a result, it was determined that grapevine exposed to mine gallery waters that cause environmental contamination may cause non-carcinogenic risks on human health.
AtıfScopus1OpenAlex1İncele - MakaleAçık Erişim2021Scopus SJRQ1Assessment of potential health risk associated with the use of Cladophora fracta as mulch
Öbek, Erdal; Topal, E. Işıl Arslan; Topal, Murat
In this study, cadmium, copper, nickel, zinc, chromium, manganese and lead were determined in Cladophora fracta present in Lake Hazar (Turkey). The health risks (non-carcinogenic and carcinogenic) of heavy metals associated with the use of Cladophora fracta as mulch were also determined. Bioconcentration factor (BCF) and metal pollution index (MPI) were calculated. When compared with reference value (1.5 mg/kg for Cr and 200 mg/kg for Mn), the highest accumulation by Cladophora fracta was seen in the month of June as 1442 ± 7.2% (23.13 mg/kg) for Cr and the lowest accumulation calculated in the month of July as 5 ± 0.2% (210 mg/kg) for Mn. In our study, the highest MPI value was 13.69 in September. The magnitude of MPI values of heavy metals determined during April to September appeared in the following order September > August > July > June > May > April. The HQing (hazard quotient due to ingestion) and HQinh (hazard quotient due to inhalation) in all months were chidren > female > male while the order of HQder (hazard quotient due to dermal) was determined as male > female > children. Non-carcinogenic risk (HQ) and Hazard Index (HI) values in terms of ingestion, inhalation and dermal ways were lower than 1. Also, total HI values were < 1. As a result, there was not non-carcinogenic and carcinogenic risks associated with usage of Cladophora fracta as mulch.
AtıfScopus4WoS4OpenAlex4İncele - MakaleAçık Erişim2020Investigation of Air Quality in Terms of Microbiological Density in Some Regions of the European Side of Istanbul Province
Erguven, Gokhan Onder; Aydin, Sumeyye; Bayhan, Hurrem; Ikizoglu, Bahar
Microbial fauna of the outdoor ambient air of Istanbul has been determined in European side of Istanbul province at four differentdistricts (Bakirkoy, Fatih, Basaksehir and Esenler) by active and passive sedimentation sampling methods. In addition tometeorological factors, the effect of urbanization and traffic density for the air microbial load is also determined. Outdoor airsampling was performed between April 2014 and November 2015. The sedimentation method was done by standart plate count agar(PCA) opening the cover of the petri dishes containing a prepared medium. Standart plate count agar (PCA) medium was used for thedetermination of total bacteria while malt extract agar (MEA) was used for fungi. The colonies formed at the end of this period werecounted and total number of bacteria and fungi per unit volume and area were determined. Air temperature, relative humidity, windspeed and direction were also recorded. As a result of the active sampling method, the most counted units of bacteria was determinedat 35°C in Basaksehir station as 222 CFU(Colony forming unit)/m³, maximum fungal was determined as 286 CFU/m³at 20°Cincubation temperature. The maximum amount of bacteria in the passive sampling method results at 35°C was in Bakirkoy station as9250 CFU/m³.
- MakaleAçık Erişim2020Üniversite öğrencilerine verilen meme kanseri ve kendi kendine meme muayenesine yönelik eğitimin öğrencilerin kaygı düzeyine ve sağlık inançlarına etkisi
Durmaz, Yadigar Çevik; Doğan, Runida; Polat, Hilal Türkben; Uzun, Ela; Şakar, Hüseyin; Önder, Eylem Yalçınkaya
Amaç: Araştırmanın amacı meme kanseri ve kendi kendine meme muayenesi eğitiminin öğrencilerin kaygı seviyesi ve sağlıkinançları üzerine etkisini incelemektir.Yöntem: Bu çalışma tek grup öntest-sontest desenli, yarı deneysel türde bir çalışmadır. Örneklem seçiminde kolay ulaşılabilirdurum örneklemesi yöntemi kullanılmıştır. Araştırmanın evrenini Türkiye’nin Doğu Anadolu Bölgesi’nde bulunan bir devletüniversitesinin kız öğrencileri, örneklemini ise bu öğrencilerden araştırmaya katılmayı kabul edenler oluşturmuştur.Çalışmaya gönüllülük esasıyla toplamda 126 öğrenci katılmıştır. Veri toplama araçları olarak; “Kişisel Bilgi Formu”,“Champion’un Sağlık İnanç Modeli Ölçeği” ve “Hamilton Anksiyete Derecelendirme Ölçeği” kullanılmıştır.Bulgular: Öğrencilerin % 84.1’inin kendi sağlığını iyi olarak değerlendirdiği, % 93.7’sinin ailesinde meme kanseri olmadığıbelirlenmiştir. Eğitim sonrasında, öğrencilerin sağlık inançlarında gelişme görülürken, kaygı düzeylerinde azalma tespitedilmiştir. Sağlık İnanç Modeli Ölçeğinin alt boyut toplam puanları incelendiğinde, eğitim sonrasında, algılanan duyarlılık vealgılanan güven alt boyut puanlarının istatistiksel olarak anlamlı düzeyde arttığı, algılanan engel puanının istatistiksel olarakanlamlı düzeyde azaldığı görülmüştür (p˂0.05).Sonuç: Meme kanseri ve kendi kendine meme muayenesi eğitiminin öğrencilerin kaygı düzeyi ve sağlık inançları üzerinde etkiliolduğu belirlenmiştir. Eğitim sonrasında öğrencilerin kaygı düzeyinde düşme gözlenirken, sağlık inançlarının geliştiğibelirlenmiştir.
AtıfOpenAlex5TR Dizin2İncele - MakaleAçık Erişim2020Çeşitli Pekmez Türlerinde Farklı Yöntemlerle Tespit Edilen Antioksidan Aktivitelerin Karşılaştırılması
Benzer, Fulya; Tüzün, Sabri; Baş, İsa; Karaca Sanyürek, Nesrin; Karakavuk, Emrah
Bu çalışmada piyasadan alınmış olan Nar (Punica granatumL.), Keçiboynuzu (Ceratonia siliqua L.), Karadut (Morus nigraL.), Dut (Morus albaL.) ve farklı bölgelerden alınan Üzüm (Vitis viniferaL.) pekmezlerinin farklı yöntemlerle antioksidan aktivitelerinin ölçümü yapılmıştır. Pekmez çeşitlerinin radikal süpürme gücü DPPH ve ABTS yöntemleri ile, Toplam Fenolik Madde tayini ise Folin metoduyla belirlenmiştir. Çalışma sonucunda yapılan istatistiksel analizlerde ABTS yok etme aktivitesi bakımından Nar, Keçiboynuzu, Mardin Üzüm pekmezi, Batman Üzüm pekmezi ve Karadut sırasıyla % 99.34±0.18, % 99.22±0.2, % 98.92±0.45, % 98.71±0.13, % 97.77± 0.4 ile yüksek aktivite gösterirken, Dut pekmezi % 94.65± 0.2ile en düşük aktiviteyi göstermiştir. DPPH radikal giderme aktivitesi bakımından en yüksek değer % 82.32±0.6 ile Nar, en düşük değer ise % 43.33±0.8 ile Üzüm pekmezidir. Toplam fenolik madde açısından en yüksek aktiviteye 748.74±14.43 mg GAE/100 g ileKeçiboynuzu pekmezi sahip iken, en düşük aktiviteye ise 166.14±6.8 mg GAE/100 g ile Mardin üzüm pekmezinin sahip olduğu tespit edilmiştir. Yapmış olduğumuz bu çalışmada Keçiboynuzu pekmezinin toplam fenolik madde içeriğinin diğer pekmezlerin değerinin iki katından daha fazla olması bu pekmezin antioksidan aktivitesinin daha güçlü olduğunu ortaya koymaktadır.
AtıfOpenAlex10TR Dizin2İncele - MakaleAçık Erişim2020Hematopoetik Kök Hücre Alıcılarının Taburculuk Aşamasında Öğrenme Gereksinimleri
Ister, Emine Derya; Serin, Emine Kaplan; Bayir, Berna; Erkurt, Mehmet Ali
Bu araştırma, hematopoetik kök hücre nakli uygulanan hastaların taburculuk aşamasında öğrenme gereksinimlerini belirlemek amacıyla yapılmıştır. Araştırmanın örneklemini Türkiye’de bir üniversite hastanesinin Kök Hücre Nakil Ünitesinde 2018 yılında nakil olan 100 hasta oluşturmuştur. Araştırmada veri toplama aracı olarak “Hasta Bilgi Formu” ve “Hasta Öğrenme Gereksinimleri Ölçeği” kullanılmıştır. Araştırmada veriler hasta taburcu olamadan 2-48 saat önce toplanmıştır. Hastaların ölçek toplam puan ortalaması 212.93±29.37 olup, hastaların genel olarak öğrenme gereksinimleri yüksektir. Tedavi ve Komplikasyonlar alt boyut puan ortalaması 4.40±0.61 olup hastaların öğrenme gereksinimlerinin en yüksek olduğu boyuttur. Bunu sırasıyla yaşam kalitesi, ilaçlar, yaşam aktiviteleri, toplum ve izlem, cilt bakımı ve duruma ilişkin duygular izlemektedir. Ölçek toplam puan ortalamasını cinsiyet, medeni durum, çalışma durumu, mevcut kronik hastalık, eğitim düzeyi, nakil tipi etkilememektedir (p>0.05). Hematopoetik kök hücre nakli uygulanan her hastanın öğrenim gereksinimlerinin yüksek olduğu sonucuna ulaşılmıştır.
AtıfOpenAlex3TR Dizin2İncele - MakaleAçık Erişim2020Investigation of midwifery and nursing students' attitudes towards evidence-based nursing
Serin, Emine Kaplan; Dal, Nursel Alp; İkde Öner, Özlem
The objective of this study is to explore the midwifery and nursing students’ attitudes towards evidence-based nursing. The sample of this descriptive and cross-sectional study included 626 undergraduate students studying midwifery/nursing at a state university in the Eastern Anatolia Region of Turkey. The data were collected using the “Descriptive Form for Students” and the “Evidence-Based Nursing Attitude Questionnaire (EBNAQ).” The mean total score of the students in EBNAQ was 55.46±9.92, their mean score in the subscale “Beliefs and Expectations About Evidence-Based Nursing” was 27.24±5.87, their mean score in the subscale “Evidence-Based Practice Intention” was 13.83±3.00, and their mean score in the subscale “Sentiments on Evidence-Based Nursing” was 14.38±4.01. A significant relationship was determined between gender, academic year of study, liking the profession, doing research, duration of internet usage and duration of medical information acquisition and the mean total scores in EBNAQ (p<0.05). The results demonstrated that the students had highly positive attitudes toward evidence-based practices. Determination of the attitudes of students regarding evidence-based practices will help development of strategies towards increasing evidence-based midwifery and nursing practices through education.
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