Yazarlar
- Gul, Muhammet(35)
- Erten, Fusun(23)
- Zengin, Gokhan(23)
- Benzer, Fulya(22)
- Dal, Nursel Alp(20)
- Sahin, Kazim(20)
- Orhan, Cemal(19)
- Yeşiltepe, Akgün(17)
- Topal, Murat(15)
- Yucesan, Melih(15)
- Yildirim, Ozal(13)
- Öbek, Erdal(13)
- Aksakal, B.(12)
- Gürarslan Baş, Nazan(12)
- Alp Dal, Nursel(11)
- Baloglu, Ulas Baran(11)
- Cakilcioglu, Ugur(11)
- Kandemir, Fatih Mehmet(11)
- Paksoy, Mehmet Yavuz(11)
- Talo, Muhammed(11)
- Celik, Erkan(10)
- Er, Besir(10)
- Say, Yakup(10)
- Yaman, Mine(10)
- Yüksekol, Özlem Doğan(10)
- Aksu, Önder(9)
- Aslan, N.(9)
- Aslan, Naim(9)
- Baş, Kazım(9)
- Erişir, Mine(9)
- Mahomoodally, Mohamad Fawzi(9)
- Acharya, U. Rajendra(8)
- Caprioli, Giovanni(8)
- Karatay, Gülnaz(8)
- Kocabaş, Mehmet(8)
- Macit, Arife(8)
- Parlak Ak, Tuba(8)
- İpek, Yeliz(8)
- Beydağ, Kerime Derya(7)
- Camas, Mustafa(7)
Yayınlar
- Derleme MakaleAçık Erişim2020Healthy Lifestyle Behaviours, Quality of Life and Motivational Interviews in the Menopausal Period
Orhan, Ilksen; Yağmur, Yurdagül
Menopause, as one of the important turning points of women's life, is the permanent cessation of menstruation by the result of the loss of ovarial functions with the marked decrease in estrogen production in ovaries. It is known that, women in the menopausal period experience at least one of the symptoms caused by hormonal changes. Providing information about menopause to the women in the menopausal period by the healthcare professionals who have received special training, and providing health education and counseling to meet the basic needs of women will contribute in improving the healthy lifestyle behaviours of women and increasing their quality of life. Motivational interviews are an alternative communication technique that can be used to cope with menopausal complaints and to improve the quality of life by developing a healthy lifestyle for menopause. Nurses’ alternative communication technique usage by using their educational, counselor, researcher, practitioner and supportive roles is very important in solving the problems of women in the menopausal period. For this reason, in the review, the conceptual framework regarding motivational interviews in supporting healthy lifestyle behaviours and quality of life has been examined in line with the literature.
AtıfOpenAlex16TR Dizin1
İncele - MakaleAçık Erişim2020Trace Metal Profiles of Human Hair and Nail Samples Collected from Urban and Rural Areas of Zonguldak, Turkey
Ören, Muhammet; Çabuk, Hasan; Alataş, Mevlüt; Uyar, Güray; Uyar, Aysel
Hair and nail samples were collected during a period of October to December 2012 from 63 healthy humans whohave been living in Zonguldak for at least ten consecutive years. The humans aged over 30 years and having noserious health problems were participated in the study. The methodology involved the collection, ultrasoniccleaning and microwave digestion of samples. The measurements of trace metals (As, Cu, Zn, Se, Cd, Pb, Cr, Feand Ni) in samples were performed with ICP-MS. The predominant metals determined in the both hair and nailsamples were the essential metals with the decreasing concentrations in the order of Zn>Fe>Cu. Other metalsdetermined in the hair samples followed the concentration order of Pb>Se>Ni>Cr>As>Cd, whereas in the nailsamples, the order was Se>Ni>Cr>Pb>As>Cd. Subgroups were formed according to location and gender. Se andFe concentrations in hair samples obtained from urban residents were significantly higher. With regard to nailsamples, the rural residents exhibited more elevated Fe levels significantly. Gender had a significant influence onthe concentration of Zn and Cu in hair samples with females presenting higher values. However, the effect ofgender on the trace metal concentrations in nail samples was negligible. The metal concentrations obtained forZonguldak were within or below the values reported worldwide.
AtıfOpenAlex3TR Dizin3İncele - MakaleAçık Erişim2020Sexual health problems in obstetrics and gynecology outpatient clinics: A retrospective study
Dal, Nursel Alp; Ozdemir, Cagdas
OBJECTIVE: With this study, it was aimed to retrospectively examine the individuals who applied to obstetrics and psychiatry outpatient clinics of a public hospital between 2007–2019 due to sexual health problems. MATRERIAL and METHODS: Medical records of all individuals who applied to obstetrics and gynecology outpatient clinics between 2007– 2019 for sexual health problems were included in the study. Medical records of a total of 428 patients were examined using a form that assesses the socio-demographic and medical characteristics of individuals. RESULTS: 89.3% of the applicants were male, 42.9% of the men and 50% of the women were between the ages of 32–42. While 65.2% of women applied for non-organic vaginusmus, 51.6% of men applied with the diagnosis of premature ejaculation. Considering the application date of women, 47.8% applied between 2011 and 2014, while 66.5% of men applied between 2015 and 2019. While 69.6% of women applied from the city center, 58.4% of men applied from the city center. While no result was specified in 80.4% of women, no result was reported in 91.1% of men. CONCLUSION: Sexual health problems are the most non-organic vaginismus in women, while premature ejaculation in men. Examining the applications due to sexual health problems is important in terms of recognizing, formulating and treatment problems that may arise later
- MakaleAçık Erişim2020Bir Devlet Üniversitesi Hemşirelik Bölümü Öğrencilerinde Malpraktis Eğilimi
Durmaz, Yadigar Çevik; Doğan, Runida
Bu araştirma hemşireliköğrencilerinin tıbbi uygulama hatası eğilimlerini belirlemek amacıyla tanımlayıcı tipte yapıldı.Araştırmanın evrenini bir devlet üniversitesi hemşirelik bölümü 2.sınıf, 3.sınıf ve 4.sınıf öğrencileri, araştırmanın örneklemini ise bu öğrenciler arasından araştırmaya katılmaya gönüllü öğrenciler oluşturdu. Araştırma verileri 1 Ocak 2018-30 Ocak 2018 tarihleri arasında toplandı(n:322). Verilerin toplanmasında Kişisel Bilgi Formu ve Malpraktis Eğilim Ölçeği kullanıldı. Toplanan veriler;yüzde, ortalama, t-testi, ANOVA ve Pearson korelasyon testleri kullanılarak analiz edildi. Bu çalışma‘agree’adında bir uygulama yönergesi kullanılarak bildirilmiştir (Bkz.Ek.1).Araştırmaya katılan hemşirelik öğrencilerinin Malpraktise Eğilim Ölçeği’ndenaldıkları toplam puan ortalamasının 195,7±24,5 olduğu ve tıbbi hata yapma eğilimlerinin düşük düzeyde olduğu belirlendi. Hemşirelik öğrencilerinin Malpraktis Eğilim Ölçeği’nin alt boyutlarından en az hata eğilimine sahip oldukları alt boyutun “ilaç ve transfüzyon uygulamaları”, en fazla hata eğilimine sahip oldukları alt boyutun ise “düşmeler” olduğu belirlendi. Kadın öğrencilerin malpraktis eğiliminin erkek öğrencilere göre daha düşük olduğu ve meslekten memnuniyet düzeyi arttıkça malpraktis eğiliminin düştüğü belirlendi (p˂0.05).Araştırma sonunda hemşirelik öğrencilerinin malpraktis eğilimlerinin düşük olduğu belirlendi. Bununla birlikte öğrencilerin “düşmeler” hata eğilimi daha yüksek olduğu için bu konuların müfredatta hasta güvenliği ve tıbbi hatalarla ilgili olarak gözden geçirilmesi önerilmektedir.
AtıfOpenAlex2TR Dizin2İncele - MakaleAçık Erişim2020Üniversite Öğrencileri Arasındaki Hemşirelik Mesleği İmajınınBelirlenmesi
Serin, Emine Kaplan; Orhan, Ilksen
Amaç: Bu çalışma, üniversite öğrencilerinin hemşirelik mesleği imajını belirlemek amacıyla yapıldı. Gereç ve Yöntemler: Tanımlayıcı ve kesitsel nitelikte ki araştırma, 2019-2020 eğitim-öğretim yılında Türkiye’nin doğusunda bir devlet üniversitesi’nin merkez kampüsü içinde bulunan fakülte ve yüksekokullara kayıtlı 447 lisans öğrencisi ile yürütüldü. Araştırmada örneklem seçimine gidilmezken, verilerin toplanmasında araştırmacılar tarafından oluşturulan “Kişisel Bilgi Formu” ve “HİÖ (Hemşirelik İmajı Ölçeği)” kullanıldı. Verilerin değerlendirilmesinde tanımlayıcı istatistikler; sayımla belirlenen değişkenler için sayı ve yüzde, ölçümle belirlenen değişkenler için ortalama ± standart sapma şeklinde gösterildi. Bağımsız gruplarda t testi, varyans analizi (ANOVA), Kruskal Wallis testi, Mann Whitney-U testi, LSD Post Hoc testi ve Pearson korelasyon analizi kullanıldı. İstatistiksel anlamlılık düzeyi 0.05 olarak kabul edildi. Bulgular: Araştırmaya katılan bireylerin yaş ortalamasının 21,98±2.35 olduğu, %53,5’inin erkek ve %61,5’inin ailesinde veya yakın çevresinde hemşire olduğu saptandı. Bireylerin HİÖ “genel görünüm” alt boyutu puan ortalaması10,13±2,01, “iletişim” alt boyutu puan ortalaması 10,70±3,27, “mesleksel ve eğitimsel nitelikler” alt boyut puan ortalaması 24,43±5,72 ve HİÖ toplam puan ortalaması 45,28±8,79 olarak bulundu. HİÖ toplam puan ortalaması ile cinsiyet, gelir durumu, geldiği coğrafi bölge, en uzun yaşanılan yer, aile veya yakın çevresinde hemşire ve erkek hemşire varlığı, daha önce hemşireden hizmet alma durumu, hemşire olmayı isteme durumu, hemşirelik mesleğinin hangi cinsiyete özgü olduğu düşüncesi arasında istatistiksel olarak önemli fark olduğu saptandı (p<0,05). Sonuç: Çalışmaya katılan bireylerdeki hemşirelik imajının orta düzeyde olumlu olduğu, gelir durumu düşük ve erkek bireylerde hemşirelik imajının daha yüksek düzeyde olumlu olduğu saptandı.
AtıfOpenAlex1TR Dizin2İncele - MakaleAçık Erişim2020The Effect of N-Acetylcysteine on Oxidant/Antioxidant Status in Irradiated Rats
Baykara, Murat; Özçelik, Mehtap; Erisir, Mine; Guler, Osman
N-Acetylcysteine (NAC) is both a strong antioxidant and a glutathione precursor. The effect of NAC on the oxidant/antioxidant status of some tissues of the irradiated rats was investigated. Twenty one rats were assigned to 3 groups; the control group, the irradiation group, for which physiological saline solution was administered as i.p. for three days and then, 9 Gy gamma irradiation was applied, and 3rdirradiation + NAC group for which NAC was adminis-tered as i.p. for three days as 300 mg/kg body weight and then the same dose of irradiation was applied. Upon irradia-tion, the increase determined in malondialdehyde (MDA) was significant in the liver, kidney, and brain tissues of the rats (P˂0.05). While glutathione peroxidase (GSH-Px) activity decreased in all of the tissues and superoxide dismutase (SOD) activity only in the liver (P˂0.01), glutathione (GSH) levels significantly increased in the kidney and ovarium tissues (P˂0.001). While NAC administration returned the increased MDA levels in the kidney and brain as a result of irradiation to normal levels (P˂0.05), it was determined that it did not return the increased MDA levels in the liver tissue to the normal level (P˂0.001). While NAC addition led to a significant increase in GSH levels of the liver, heart, spleen, brain and ovarium tissues compared to both control and irradiation groups, it caused a significant decrease in the kid-ney tissue compared to irradiation group (P˂0.001). As a result of NAC addition, a significant decrease was determined in spleen GSH-Px activity, heart and ovarium SOD activity compared to control and irradiation groups (P˂0.05). It can be asserted that GSH increasing by the addition of NAC is the main antioxidant that has a role in decreasing oxidative stress occurring as a result of irradiation. In the examination of MDA values, it was found that the addition of NAC pro-tected the kidney and brain against the oxidative damage induced by irradiation but NAC addition could remain insuffi-cient for the liver.
AtıfOpenAlex2İncele - MakaleAçık Erişim2020Deneysel Otizm Spektrum Bozukluğu Modeli Oluşturulan Sıçanlarda Likopenin Beyin IL–6, IL–10, FGF–2 ve NGF Düzeyleri Üzerine Etkisi
Sahin, Kazim; Erten, Fusun; Gencoglu, Hasan
Otizm spektrum bozukluğu (OSB), batılı ve gelişmiş toplumlarda artan bir sorundur. Doğası gereği büyük ölçüde genetik olmasına rağmen,birçok çevresel faktör hassas popülasyonlarda OSB'yi tetiklemede rol oynayabilmektedir. Propiyonik asit (PPA) uygulaması, anormal nöralhücre organizasyonunu ve ardından otizm benzeri nörodavranışları içeren kritik değişiklikleri indükleyebilmektedir. Likopen vemetabolitleri beyinde kontrol edilebildiğinden, likopenin merkezi sinir sisteminde nöroprotektif etkileri olabileceği ve başlıca beyin biyobelirteçleri üzerinde modülasyona neden olabileceği düşünülmektedir. Bu çalışmada, 35 adet üç haftalık yaşta Sprague Dawley ırkı erkeksıçan 5 gruba ayrıldı: i) Kontrol. ii) PPA; (500 mg/kg/ip). iii) PPA+LI (PPA’ya ek olarak, 5 mg/kg/gün intragastrik likopen verilen grup), iv)PPA+LII; (PPA’ya ek olarak, 10 mg/kg/gün intragastrik likopen verilen grup), v) PPA+LIII, (PPA’ya ek olarak, 20 mg/kg/gün intragastriklikopen verilen grup). Çalışma sonunda hayvanlar dekapite edildi ve beyin dokuları alınarak homojenize edildi ve SDS-PAGE ve westernblot teknikleriyle beyinde enflamatuar sitokinler interlökin 6 ve 10 (IL6/IL10) ile temel fibroblast büyüme faktörü (FGF-2) ve sinir büyümefaktörü (NGF) düzeylerinin değişimi tespit edildi. Elde edilen sonuçlara göre 35 günlük uygulama sonunda likopenin, PPA ile OSB modelioluşturulan sıçanlarda, PPA’ya bağlı olarak artan IL–6 ve IL-10 düzeylerini özellikle PPA+LIII ve PPA+LII grubunda düşürdüğü tespit edildi.Bununla birlikte, FGF–2 ve NGF düzeyleri de her üç likopen grubunda da belirgin olarak PPA verilen gruba göre artış gösterdi (P<0,0001).Sonuç olarak, likopen, PPA ile indüklenen OSB benzeri nöropatolojik bozuklukları beyin inflamatuar sitokinleri ve büyüme faktörleriniregüle ederek azaltabilir.
- MakaleAçık Erişim2020Scopus SJRQ4Meslekyüksekokulu öğrencilerinin covid 19 pandemi sürecinde çevrimiçi öğrenmeye ilişkin hazır bulunuşluk ve tutum düzeyleri arasındaki ilişkinin çeşitli değişkenler açısından incelenmesi
Gömleksiz, Mehmet Nuri; Pullu, Emine Kübra
Bu araştırmanın amacı meslek yüksekokulu öğrencilerinin Covid-19 pandemi sürecinde çevrimiçi öğrenmeye ilişkin hazırbulunuşluk ve tutum düzeyleriarasındaki ilişkiyi ortaya koymaktadır. Araştırmanın çalışma grubunu Türkiye’de İç Anadolu Bölgesi’ndeki bir üniversitenin meslek yüksekokulu öğrencileri oluşturmaktadır. Araştırmada veri toplama aracı olarak “Çevrimiçi ÖğrenmeHazırbulunuşluk Ölçeği” ve “Çevrimiçi Öğrenme Tutum Ölçeği” kullanılmıştır.Ölçek 264 kadın ve 48 erkek olmak üzere toplam 312 öğrenciye uygulanmıştır.Verilerin çözümlenmesinde öncelikle Kolmogorov-Smirnov testi uygulanarakverilerin normal dağılım gösterdiği belirlenmiştir. Daha sonra veriler cinsiyet, sınıf düzeyi, teknoloji kullanma düzeyi ve internet kotası değişkenleri için bağımsız gruplar t testi; bölüm ve sisteme bağlanmak için kullanılan teknolojik cihazdeğişkenleri için ise varyans testi kullanılarak analiz edilmiştir. Öğrencilerin çevrimiçi öğrenmeye ilişkin hazırbulunuşluk düzeyi ile tutumları arasındaki ilişkiyiölçmek için Pearson Korelasyon katsayısı kullanılmıştır. Araştırma sonucundaöğrencilerin çevrimiçi öğrenmeye ilişkin hazırbulunuşluk düzeyleri ile çevrimiçiöğrenmeye ilişkin tutumlarını birbirlerini pozitif yönde etkilediği belirlenmiştir.
AtıfOpenAlex16TR Dizin9İncele - MakaleAçık Erişim2020Study of The Relationship Between Emotional Intelligence and Goal Commitment Levels in Athletes
Göral, Kemal; Özcan, Ecesu
The aim of the study is to investigate the relationship between emotional intelligence and goal commitment levels in athletesdoing individual and team sports. The study group of the research consists of 427 licensed athletes who study at SportsSciences Faculties of 6 universities in Aegean Region of Turkey in 2018-2019 academic year. In order to measure the level ofgoal commitment and emotional intelligence in athletes ‘Emotional Intelligent Scale’ and ‘Goal Commitment Scale’ wereused in the current study. In order to find answers to the sub-problems of the study, t-Test, Pearson correlation coefficientanalysis and Cohen’s d analysis wereused. The results obtained from the analyses revealed that the goal commitment andemotional intelligence mean scores of the female athletes doing individual or team sports are higher than those of the maleathletes. Moreover, the mean scores of the athletes doing team sports were found to be higher than those of the athletes doingindividual sports and the emotional intelligence mean score of the professional athletes doing individual sports was found tobe higher than that of the amateur athletes. According to the results of the correlation analysis, there is a significant correlationbetween the goal commitment and emotional intelligence mean scores of both the athletes doing individual sports and theathletes doing team sports. As a conclusion, regardless of being engaged in an individual sport or a team sport, increasingemotional intelligence was found to be leading an increase in goal commitment in both of the groups. This positive correlationis believed to make important contributions to literature and academicians working in this field, coaches, conditioners andsports psychologists to achieve high level of achievement and performance.
AtıfOpenAlex4İncele - MakaleAçık Erişim2020Screening of Antimicrobial Effect against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea saligna (C. Koch) Wagenitz from Turkey
Cakilcioglu, Ugur; Sönmez, Pınar Erecevıt
In this study, the antimicrobial effect researched on microorganisms threatening to human health of extract including methanol of Centaurea saligna that is endemic and used for therapy of many diseases. For disk diffusion method, this related extract is highly effective on the gram negative bacteria by its 20.3±0.5 mm inhibition area. Again to relation bacteria, gram positive bacteria are highly effective by 18.3±0.57 mm and 20.3±0.5 mm inhibition area. It has a effect against Candida species and Epidermophyton sp., the superficial skin infections are caused, by 9.6±0.5 mm and 13.6±1.5 mm inhibition area. On the other hand, for findings, this related extract is extremely effective against Trichophyton sp. that is one of dermatophyte fungi by 24.6±1.5 inhibition area. This natural extract shows its antimicrobial effect namely, by minimal inhibition value (MIC): 6.25 µL its lowest inhibition value against development of all the bacteria and dermatophyte fungi. This plant has a potential to be a natural antimicrobial agent to be used as a medicine for human health and life quality.
AtıfOpenAlex5TR Dizin2İncele - MakaleAçık Erişim2020SARS CoV-2 nsp1 Mutasyonlarının Protein Yapıda Ortaya Çıkardığı Değişimler
Akbulut, Ekrem; Kar, Bülent
Şiddetli akut solunum yolu sendromu koronavirüsü 2 (SARS CoV-2) pozitif polariteli ve tek iplikli bir RNA virüsüdür. Virüsün sebep olduğu COVID19 hastalığı on ay gibi kısa bir sürede 900 binden fazla insanın ölümüne neden oldu. Virüs ile mücadelede etkin ve spesifik bir ilaç ve aşı henüz bulunmamaktadır. İlaç ve aşı geliştirme çalışmaları virüsün yapısal ve fonksiyonel özelliklerinin kapsamlı bir şekilde anlaşılmasını gerekli kılmaktadır. Hızlı yayılım gösteren virüsün yüksek mutasyon hızı geliştirilecek aşı ve ilaçların etkinliklerini sürdürebilmelerinin önündeki en büyük engellerden biridir. Hücresel boyutta viral enfeksiyonun başlangıcında yer alan SARS CoV-2 yapısal olmayan protein 1 (nsp1) önleyici tedavi için potansiyel hedef proteindir. Konak hücre translasyonunu engelleyen nsp1’in yapısının bilinmesi önemlidir. Bu çalışmada 222 Avrupa izolatında görülen nsp1 mutasyonlarının protein yapıda ortaya çıkarabileceği değişimler yapay zekâ tabanlı bir modelleme yazılımı olan trRosetta kullanılarak modellenmiştir. NCBI Virüs veritabanından elde edilen dizi bilgileri MAFFT çoklu dizi hizalama programı ile hizalanmıştır. Mutasyon analizleri RDP4 yazılımı ile yapılmıştır. Mutant protein primer yapı MegaX yazılımı ile oluşturulmuştur. Protein kalite skorları QMEAN algoritması kullanılarak analiz edilmiştir. Proteinleri fizikokimyasla özellikleri ProtParam ExPAsy programı ile yapılmıştır. Elde edilen protein yapıların konformasyonel analizleri PyMOL ile yapılmıştır. SARS CoV-2 Avrupa izolatlarında görülen nsp1 mutasyonlarının protein sekonder ve tersiyer yapısında konformasyonel ve topolojik değişimlere neden olabileceği tespit edilmiştir. SARS CoV-2 katalitik bölgeyi içine alan P153 ve N178 rezidüleri arasında kalan bölgede görülen değişimin proteinin fonksiyonel özelliklerini etkileyebileceği düşünülmektedir. Elde edilen verilerin önleyici ve tedavi edici yaklaşımlara önemli veriler sunabileceği düşünülmektedir.
AtıfOpenAlex1TR Dizin2İncele - MakaleAçık Erişim2020The Effect of the Level of Self-Efficacy Confidence of the Nurses on Their Performance: Example of Elazig Province
Düsükcan, Muhammet; Sezgin, Eray Ekin
With this study, it was aimed to determine the level of self-efficacy beliefs and how these beliefs affect their performance of nurses working in hospitals in the city of Elazig. Nurses of hospitals operating in the city of Elazig constitute the universe of research. There are a total of 8 hospitals including 4 public and 4 private in Elazig. A total of 1,535 nurses are employed in these hospitals. The sample consists of 309 randomly selected nurses representing the universe. In this study, the quantitative research method has been used and data obtained through the face -to-face survey technique. In this study, the main statistical analyses used are descriptive statistics, reliability analysis and regression. The study findings showed that the nurses' self-efficacy belief levels (X=4.27; sd=0.52) and performances (X=4.11; sd=0.64) was high. Self-efficacy belief levels was found to have a positive low effect on employee performance. Self-efficacy may be effective at a rate of 6% on employee performance (r=0.253; r2=0.064; p<0.001).
AtıfOpenAlex20TR Dizin11İncele - Derleme MakaleAçık Erişim2020A Study on Historical/Social Traumas and the Forms of Intergenerational Transmission
Karatay, Gülnaz
Historical/social traumas such as war, migration, natural disasters and genocide have multidimensional devastating effects on the survivors. However, subsequent generations also absorb the experiences of their parents in different ways, even if they were not directly exposed to trauma, and their stress-response systems may become vulnerable. This situation, which indicates the contagious nature of social traumas, is expressed in the concepts such as “secondary traumatization” or “intergenerational transmission of trauma”. In the past two decades, there have been an increasing interest in, and modelling studies on the forms of intergenerational transmission of trauma. Scientific studies reveal that, despite some disadvantages of the retrospective method, social/historical traumas continue to affect subsequent generations through psychodynamic, environmental, cultural and epigenetic mechanisms. It is stated that intra-family communication patterns play an important role especially in the processes of trauma transmission and the generation effect may be experienced more heavily in the families who failed to achieve posttraumatic growth. This review article, discussing intergenerational transmission of trauma, aims to create a perspective on the phenomenon by reviewing the literature on the forms of intergenerational transmission of trauma and concordantly, to contribute to a better understanding of the cost of social traumas.
AtıfOpenAlex8TR Dizin7İncele - MakaleAçık Erişim2020Determination of the tendency of imprudent behavior and malpractice in nursing students of a state university
Işık, Kevser; Çevik Durmaz, Yadigar; Doğan, Runida; Serin, Emine Kaplan
Aim: This study was conducted to determine the tendency of imprudent behavior and malpractice in nursing students of a stateuniversity.Material and Methods: The sample of this descriptive cross-sectional study consisted of 103 students.Results: The vast majority of the students indicated factors such as small number of nurses working, high workload, fatigue, stressand loading nurses with off-duty jobs as causes of medical malpractice.Conclusion: The majority of medical malpractices occur due to preventable imprudent behavior. Although the tendency of nursesto perform medical malpractice appears to be low, providing trainings on reducing medical malpractices may contribute to raisingawareness on patient safety.
AtıfOpenAlex3TR Dizin1İncele - MakaleYalnız künye2020Scopus SJRQ3The Use of Astacus leptodactylus (Eschscholtz, 1823) as a Test Species for Toxicity Evaluation of Municipal Wastewater Treatment Plant Effluents
Yildirim, Cikcikoglu N.; Aksu, O.; Tatar, S.; Yildirim, N.
This study evaluated the responses of biochemical biomarkers in Astacus leptodactylus exposed to treated municipal effluents discharged into Keban Dam Lake, Elazig Elazig, Turkey. A. leptodatyclus were exposed to treated municipal effluents and Catalase (CAT), Superoxide dismutase (SOD) activity and lipid peroxidation (TBARS), glutathione (GSH) levels were measured as oxidative stress biomarkers. SOD activity was increased after exposing to treated municipal effluents for 24th and 96th h. CAT activities were decreased from 25.29 to 14.12 nmol/min/ml compared to control in the group exposed to treated municipal effluents for 24 h but it increased after 96 h exposure. GSH levels were decreased from 9.08 to 3.77 mu M compared to control, but MDA levels were increased both at 24 th h and 96 th h after exposure to treated municipal effluents. CAT, SOD activities and MDA and GSH levels in the hepatopancreas of A. leptodactylus are sensitive and suitable biochemical biomarkers for evaluating the toxicity of the treated municipal effluent complex mixtures. Treated municipal effluents exposure was found to cause sub-lethal responses in A. leptodactylus suggesting oxidative stress.
AtıfWoS2OpenAlex3
İncele - MakaleYalnız künye2020Scopus SJRQ2Metallic nanoparticles as X-Ray computed tomography (CT) contrast agents: A review
Aslan, Naim; Ceylan, Burhan; Koç, Mümin Mehmet; Findik, Fehim
X-ray computed tomography vastly used in both medical purposes and in the research of biological and non-biological materials/samples. Some of the medical applications performed in the clinics requires special protocols where contrast agents may be needed to enhance the contrast. Iodine based contrast agents are commonly used in such applications. Iodine based contrast agents were found hazardous to the environment and some patients has iodine in tolerance due to thyroid origin diseases. Scientists from different fields try to develop contrast agents which can be an alternative to iodine based contrast agents. Metallic nanoparticles have potential to be used as CT contrast agent since metals has high X-ray attenuation and high density. Metal nanoparticles considered as toxic to the living organisms. Covering nanoparticles with organic molecule often reduce toxicity and enhance the biocompatibility. Decoration of nanoparticles with function groups give them targeting properties where special organ and/or tissue can be targeted. Up to now, different studies illustrated the importance of the multipurpose properties of the metallic nanoparticles. In this report, we assessed the metal nanoparticles reported as X-ray computed tomography contrast agent. For the first time in the literature we listed in vivo contrast enhancement, targeted drug delivery and dual/multipurpose imaging properties of each metallic nanoparticles. Therapeutic effects of metallic nanoparticles such as photothermal therapy and magnetic hyperthermia were also addressed. A chart showing relative contrast enhancement properties of the nanoparticles were produced.
AtıfScopus127OpenAlex134
İncele - MakaleYalnız künye2020Scopus SJRQ1A deep convolutional neural network model for automated identification of abnormal EEG signals
Yıldırım, Özal; Baloglu, Ulas Baran; Acharya, U. Rajendra
Electroencephalogram (EEG) is widely used to monitor the brain activities. The manual examination of these signals by experts is strenuous and time consuming. Hence, machine learning techniques can be used to improve the accuracy of detection. Nowadays, deep learning methodologies have been used in medical field to diagnose the health conditions precisely and aid the clinicians. In this study, a new deep one-dimensional convolutional neural network (1D CNN) model is proposed for the automatic recognition of normal and abnormal EEG signals. The proposed model is a complete end-to-end structure which classifies the EEG signals without requiring any feature extraction. In this study, we have used the EEG signals from temporal to occipital (T5–O1) single channel obtained from Temple University Hospital EEG Abnormal Corpus (v2.0.0) EEG dataset to develop the 1D CNN model. Our developed model has yielded the classification error rate of 20.66% in classifying the normal and abnormal EEG signals.
AtıfScopus164OpenAlex211İncele - MakaleAçık Erişim2020Scopus SJRQ1Evaluation of hospital disaster preparedness by a multi-criteria decision making approach: The case of Turkish hospitals
Ortiz-Barrios, Miguel; Gul, Muhammet; López-Meza, Pedro; Yucesan, Melih; Navarro-Jiménez, Eduardo
Considering the unexpected emergence of natural and man-made disasters over the world and Turkey, the importance of preparedness of hospitals, which are the first reference points for people to get healthcare services, becomes clear. Determining the level of disaster preparedness of hospitals is an important and necessary issue. This is because identifying hospitals with low level of preparedness is crucial for disaster preparedness planning. In this study, a hybrid fuzzy decision making model was proposed to evaluate the disaster preparedness of hospitals. This model was developed using fuzzy analytic hierarchy process (FAHP)-fuzzy decision making trial and evaluation laboratory (FDEMATEL)-technique for order preference by similarity to ideal solutions (TOPSIS) techniques and aimed to determine a ranking for hospital disaster preparedness. FAHP is used to determine weights of six main criteria (including hospital buildings, equipment, communication, transportation, personnel, flexibility) and a total of thirty-six sub-criteria regarding disaster preparedness. At the same time, FDEMATEL is applied to uncover the interdependence between criteria and sub-criteria. Finally, TOPSIS is used to obtain ranking of hospitals. To provide inputs for TOPSIS implementation, some key performance indicators are established and related data is gathered by the aid of experts from the assessed hospitals. A case study considering 4 hospitals from the Turkish healthcare sector was used to demonstrate the proposed approach. The results evidenced that Personnel is the most important factor (global weight = 0.280) when evaluating the hospital preparedness while Flexibility has the greatest prominence (c + r = 23.09).
AtıfScopus87WoS69OpenAlex97
İncele - MakaleAçık Erişim2020Scopus SJRQ11D-CADCapsNet: One dimensional deep capsule networks for coronary artery disease detection using ECG signals
Butun, Ertan; Yildirim, Ozal; Talo, Muhammed; Tan, Ru-San; Rajendra Acharya, U.
Purpose: Cardiovascular disease (CVD) is a leading cause of death globally. Electrocardiogram (ECG), which records the electrical activity of the heart, has been used for the diagnosis of CVD. The automated and robust detection of CVD from ECG signals plays a significant role for early and accurate clinical diagnosis. The purpose of this study is to provide automated detection of coronary artery disease (CAD) from ECG signals using capsule networks (CapsNet). Methods: Deep learning-based approaches have become increasingly popular in computer aided diagnosis systems. Capsule networks are one of the new promising approaches in the field of deep learning. In this study, we used 1D version of CapsNet for the automated detection of coronary artery disease (CAD) on two second (95,300) and five second-long (38,120) ECG segments. These segments are obtained from 40 normal and 7 CAD subjects. In the experimental studies, 5-fold cross validation technique is employed to evaluate performance of the model. Results: The proposed model, which is named as 1D-CADCapsNet, yielded a promising 5-fold diagnosis accuracy of 99.44% and 98.62% for two- and five-second ECG signal groups, respectively. We have obtained the highest performance results using 2 s ECG segment than the state-of-art studies reported in the literature. Conclusions: 1D-CADCapsNet model automatically learns the pertinent representations from raw ECG data without using any hand-crafted technique and can be used as a fast and accurate diagnostic tool to help cardiologists.
AtıfScopus100OpenAlex96İncele - MakaleAçık Erişim2020Scopus SJRQ1Enhanced corrosion properties of biological NiTi alloy by hydroxyapatite and bioglass based biocomposite coatings
Say, Y.; Aksakal, B.
Enhanced corrosion resistance is always an obligatory property in biomedical applications. For this purpose, the surfaces of NiTi alloy were duplex coated both by Hydroxyapatite (HA)/Silver (Ag) and BioGlass (BG)/Silver (Ag) using the sol-gel method. The surface morphologies, and corrosion behaviours of the coatings were examined via SEM, EDS, XRD, and mechanically, by means of hardness as well as adhesion and corrosion tests. SEM analyses showed that the homogenous and crack-free structures were obtained in the biocomposite coatings. Spherical-like structures in the coatings were observed and pitting type of corrosion was formed in the biocomposite coated NiTi surfaces. After the corrosion tests, enhanced corrosion resistance was observed in both HA- and BG- based coatings. However, HA-based HA/Ag coatings on NiTi alloys were obtained to have higher adhesion strength as well as higher corrosion resistance compared to the BG-based biocomposite coatings. The findings in the present study can help the design of future implants with higher corrosion resistance.
AtıfScopus38WoS37OpenAlex42İncele
