Yazarlar
- Gul, Muhammet(35)
- Erten, Fusun(23)
- Zengin, Gokhan(23)
- Benzer, Fulya(22)
- Dal, Nursel Alp(20)
- Sahin, Kazim(20)
- Orhan, Cemal(19)
- Yeşiltepe, Akgün(17)
- Topal, Murat(15)
- Yucesan, Melih(15)
- Yildirim, Ozal(13)
- Öbek, Erdal(13)
- Aksakal, B.(12)
- Gürarslan Baş, Nazan(12)
- Alp Dal, Nursel(11)
- Baloglu, Ulas Baran(11)
- Cakilcioglu, Ugur(11)
- Kandemir, Fatih Mehmet(11)
- Paksoy, Mehmet Yavuz(11)
- Talo, Muhammed(11)
- Celik, Erkan(10)
- Er, Besir(10)
- Say, Yakup(10)
- Yaman, Mine(10)
- Yüksekol, Özlem Doğan(10)
- Aksu, Önder(9)
- Aslan, N.(9)
- Aslan, Naim(9)
- Baş, Kazım(9)
- Erişir, Mine(9)
- Mahomoodally, Mohamad Fawzi(9)
- Acharya, U. Rajendra(8)
- Caprioli, Giovanni(8)
- Karatay, Gülnaz(8)
- Kocabaş, Mehmet(8)
- Macit, Arife(8)
- Parlak Ak, Tuba(8)
- İpek, Yeliz(8)
- Beydağ, Kerime Derya(7)
- Camas, Mustafa(7)
Yayınlar
- MakaleAçık Erişim2026Scopus SJRQ4Effectiveness of organic tomato (Solanum lycopersicum L.) extracts added to yeast Cell Culture against H2O2 Toxicity; [Eficácia de extratos de tomate orgânicos adicionados à cultivos de células de levadura contra la toxicidad por H2O2]
Gonayli, Selahattin; Temizer, Ibrahim Akin; Aydin, Sevinq; Kirmizikaya, Gorkem; Okutan, Tuba; Yilmaz, Okke$
Growing tomatoes in season and organically are an important factor in terms of carrying higher levels of antioxidant molecules. This study aimed to demonstrate the protective effect of extracts obtained from naturally grown tomatoes, which are widely used as food, against oxidative damage caused by hydrogen peroxide on yeast cells (Saccharomyces cerevisiae L.). Lipophilic vitamins, phytosterol content, gluathione and oxidised gluathione content were analyzed by Shimadzu brand high performance liquid chromatography, while fatty acid analysis was performed by Shimadzu GC 2010 Plus Gas Chromatography. Protein content was analyzed spectrophotometrically. The study groups were designed as control, hydrogen peroxide, tomato and tomato + hydrogen peroxide. In all groups added with hydrogen peroxide and tomato extract compared to the hydrogen peroxide group; it was observed that vitamin D2, α-Tocopherol, β-Sitosterol and Stigmasterol contents increased significantly. Again, it was observed that ergosterol level increased significantly in the D + hydrogen peroxide group compared to the hydrogen peroxide group. When the fatty acid analysis results were examined, it was determined that in all groups added to the cultured yeast with hydrogen peroxide and tomato extracts (except the B + hydrogen peroxide group), there were increases in 16:0, 16:1, n-7, 17:0, 17:1 and 18:0 fatty acid levels compared to the hydrogen peroxide group. On the other hand, when its effect on protein and gluathione levels was examined, more significant increases were determined in all groups with tomato extract addition compared to the hydrogen peroxide group. At the end of the study, it was observed that tomato extracts had positive effects against hydrogen peroxide toxicity in yeast cells, although at different levels in terms of fatty acid, vitamin and phytosterol contents.
- MakaleAçık Erişim2026Scopus SJRQ2Cadmium-induced changes in haemato-immunological, oxidative stress and antioxidant parameters of Cyprinus carpio: Protective role of curcumin
Pala, Ayşegül; Eroğlu, Mücahit; Mişe Yonar, Serpil; İspir, Ünal; Yonar, Muhammet Enis
This study examined the adverse effects of sublethal concentrations of cadmium (Cd) and the potential of curcumin (CUR) to mitigate Cd-induced toxicity. We administered 1.5 and 3 mg/L of Cd and 100 mg/kg of CUR to fish (Cyprinus carpio) separately and in combination over 14 days. At the end of the experiments, various haematological and immunological parameters, oxidative stress levels and antioxidant parameters of fish were measured, and the differences between the groups were evaluated. Simultaneous CUR treatment with Cd reversed the changes in haematological parameters in fish, increased immune responses, reduced oxidative stress and normalized the impaired antioxidant enzyme activities. In summary, our study showed that dietary supplementation with CUR may be an effective strategy to reduce the toxic effects of Cd in carp.
- MakaleAçık Erişim2026Scopus SJRQ2Electrochemical analysis of tetracycline in drug formulations with glutardialdehyde-Fe2O3 modified glassy carbon electrode
Koçak, Berna; İpek, Yeliz
In this study, a glutardialdehyde-Fe2O3 modified glassy carbon electrode (GA2–Fe2O3/GCE) was used as a sensor for the electrochemical analysis of tetracycline (TC) in drug formulations. The electrochemical behavior of TC on GA2-Fe2O3/GCE was investigated using cyclic voltammetry (CV), while the quantitative determination was performed via differential pulse voltammetry (DPV). After optimizing the experimental conditions, the linear working range, limit of (LOD) detection, and limit of quantification (LOQ) of the GA2-Fe2O3/GCE electrode developed for the electrochemical analysis of TC were found to be 1.0 × 10−6–2.0 × 10−5 M and 2.0 × 10−5–9.9 × 10−6 M; 4.78 × 10−7 M; 1.59 × 10−6 M, respectively. In the sensor application study conducted on a Tetra® Gensenta tablet to demonstrate the applicability of the developed method, the linear working range, LOD, and LOQ values of the sensor were found to be 1.0 × 10−6–14.8 × 10−5 M; 5.72 × 10−7 M and 1.74 × 10−6 M, respectively. The applicability of the method was demonstrated through tablet recovery studies, and the tablet recovery ratio was determined to be 100.94%.
- MakaleAçık Erişim2026Scopus SJRQ2Pollution estimation and health risks assessment related to the agricultural application of mussel shell-derived chitosan as organic amendment
Arslan Topal, E. Işil; Topal, Murat; Çelik, Erdal; Öbek, Erdal
In this study, estimation of pollution and assessment of health risks related to the agricultural application of mussel shell–derived chitosan as organic amendment were evaluated. Furthermore, considering WHO maximum permissible levels in soil, the application rates of chitosan to agricultural soils were calculated. Geo-accumulation index (Igeo), enrichment factor (EF), contamination factor (CF), pollution load index (PLI), and ecological risk index (ERI) were calculated. Mussel shell-derived chitosan generally did not contribute to soil metal loading when evaluated in terms of those indices. The highest hazard quotient for ingestion (HQing) across male (ML), female (FML), and children (CL) followed the order Cr > Ni > Mn >Pb >Zn >Cu, while maximum HQing among metals was observed in the order CL > FML > ML. For inhalation exposure, highest HQinh for all metals was also found in the order CL > FML > ML, with individual metal contributions following Mn > Ni > Cr >Zn >Pb >Cu. Maximum HQder exhibited the trend ML > FML > CL, and the metal-specific order for HQder was Cr > Pb > Ni >Zn >Mn >Cu. Hazard Index (HI) and Total HI for ingestion, inhalation and dermal exposure were all less than 1. Cancer risk was less than 1 × 10−6. Consequently, there were no pollution and health risks associated with the use of musselshell‑derived chitosan in agriculture as organic amendment.
- MakaleAçık Erişim2026Scopus SJRQ1Post-disaster psychological effects: identifying earthquake-induced trauma in athletes
Uğurlu, Fatih Mehmet; Güler, Muhammed; Albayrak, Veysel; Aygören, Caner
Natural disasters not only cause physical destruction but also lead to various psychological problems affecting the mental health of individuals. This study was conducted to determine the levels of post-earthquake trauma in athletes who experienced earthquakes and whether certain variables made a difference in this situation. The sample of the study consisted of 359 athletes living in 11 provinces affected by the earthquakes centered in Kahramanmaraş, Turkey, on February 6, 2023. Participants were reached using the Snowball Sampling Method. The Sociodemographic Information Form and the Post-Earthquake Trauma Level Determination Scale were used to collect data. As a result of the descriptive statistics, it was seen that athletes experienced above-average earthquake trauma (M = 65.84). When examined in terms of sociodemographic variables, it was found that women showed more symptoms of earthquake trauma than men, those who experienced the loss of relatives showed more symptoms than those who did not, and those who experienced the loss of a home showed more symptoms than those who did not. In conclusion, while exercise and physical activity are methods used to cope with trauma, being an athlete alone is not sufficient to cope with earthquake trauma. Women, whether athletes or not, experience more earthquake trauma than men. Losing relatives exacerbates the trauma caused by the earthquake. Furthermore, the loss of a home, which prevents individuals from meeting some basic physiological needs, is a significant factor in earthquake trauma.
- MakaleAçık Erişim2026Scopus SJRQ1Dietary exposure and health risk assessment of fumonisins through the consumption of maize and maize-based gluten-free products in individuals with celiac disease
Tuyben, Eylem Ezgi; Sevim, Sumeyra; Macit, Arife; Kizil, Mevlude
Introduction: Individuals with celiac disease (CD) must adhere to a gluten-free diet (GFD) and are therefore at high risk of fumonisin exposure due to their high consumption of maize and maize-based products. This study aimed to determine the concentrations of fumonisins (FB1, FB2, and FB3) in packaged gluten-free (GF) maize and maizebased products sold in Turkey and to assess dietary exposure and health risks in adults with CD using a probabilistic approach. Methods: Fumonisin concentrations of 51 GF products were analyzed by Enzyme-Linked Immonosorbent Assay (ELISA) and daily food consumption data were collected from 67 individuals with CD through a food frequency questionnaire. Exposure was estimated using Estimated Daily Intake (EDI) values and probabilistic risk assessment with Monte Carlo simulation. Results: The highest fumonisins concentrations were detected in the pasta/rice/bulgur group, while the flour/starch group was the food group contributed most to total fumonisins exposure due to higher consumption. Although the average EDI values were below the Tolerable Daily Intake (TDI; 1 μg/kg bw/day) set by European Food Safety Authority’s (EFSA) and Provisional maximum tolerable daily intakes (PMTDI; 2 μg/kg bw/day) established by Joint Expert Committee on Food Additives’s (JECFA) values, individuals at the 95th percentile approached 132.88–167.89% of the PMTDI value in the flour/starch group and 79.00–82.38% in the pasta/rice/bulgur group. Discussion: These findings highlight the need for continuous monitoring and stricter regulatory oversight and dietary guidance to protect vulnerable populations.
- MakaleAçık Erişim2026Scopus SJRQ1Influence of apple pomace and asparaginase on acrylamide levels in cookies and behavior during simulated gastric digestion: risk assessment perspectives
Sevim, Sumeyra; Macit, Arife; Farıa, Miguel A.; Viegas, Olga; Cunha, Sara C.; Kizil, Mevlude; Ferreira, Isabel M.P.L.V.O.
Cookies are widely consumed baked products; however, their contribution to dietary acrylamide (ACR) intake raises increasing health concerns. This study investigated the effects of apple pomace addition and asparaginase treatment on ACR levels in cookies, the fate of ACR during simulated gastric digestion using the INFOGEST semi-dynamic model, and the associated health risks of ACR exposure from cookie consumption. Risk assessment was conducted for adults (18–65 years) and children (3–10 years) using Monte Carlo simulation. Three formulations were evaluated: a control cookie, a cookie in which wheat flour was partially replaced with apple pomace, and a cookie containing asparaginase. Cookies formulated with apple pomace contained significantly lower ACR levels than the control (132 ± 8 μg/kg vs. 215 ± 11 μg/kg; p < 0.05), although the reduction was less pronounced than in cookies containing asparaginase (65 ± 14 μg/kg). During gastric digestion, ACR exhibited formulation-dependent release kinetics. Nevertheless, the total ACR released at the end of digestion was similar for control and pomace cookies, likely due to additional ACR formation in the stomach, despite differences in release patterns throughout digestion. Margin of Exposure (MOE) values for children remained well below 10,000, indicating a potential carcinogenic risk, although reductions of up to 59% were observed for control and pomace cookies after digestion. Target Hazard Quotient (THQ) values showed a slight increase after digestion in both age groups but remained below 1, suggesting no concern for chronic toxicity. Control cookies indicated a potential carcinogenic risk for children (ILCR = 1.56 × 10−4), whereas pomace and asparaginase formulations reduced this risk (ILCR = 9.59 × 10−5 and 4.72 × 10−5, respectively). However, simulated gastric digestion increased ILCR values for both control and pomace cookies (2.24 × 10−4 and 2.33 × 10−4, respectively). These findings indicate that dietary exposure to ACR cannot be assessed solely based on its concentration in food, and that digestive kinetics should be incorporated into health risk assessment.
- MakaleAçık Erişim2026Scopus SJRQ4Protective effects of Sodium Tetraborate on fatty acid profiles in rat hearts subject to Lead toxicity; [Efecto protector del tetraborato de sodio sobre los perfiles de ácidos grasos en el corazon de ratas, expuestas a toxicidad por plomo]
Aydin, Sevinç
This study was designed to observe the effects of sodium tetraborate on preventing lead metal toxicity damage to fatty acids in rat heart tissue. After the heart tissues were homogenized with Tris-HCl buffer, the separated pellet part was prepared for fatty acid analysis. The fatty acids in the obtained lipid extract were converted to methyl ester form and analyzed with SHIMADZU GC 2010 PLUS gas chromatography. When comparing the lead group with the lead + sodium tetraborate group, partial increases were observed in saturated fatty acid levels such as myristic acid (14:0), pentadecanoic acid (15:0), and palmitic acid (16:0), while varying increases were seen in some monounsaturated fatty acid levels such as palmitoleic acid (16:1, n-7), and oleic acid (18:1, n-9). Moreover, demonstrated varying levels of increases in all polyunsaturated fatty acids excluding the arachidonic acid (20:4, n-6) and adrenic acid (22:4, n-6) fatty acids. As the most notable fatty acid change in our study, arachidonic acid (20:4, n-6) fatty acid increasing in the lead group while decreasing in the sodium tetraborate group demonstrates that sodium tetraborate decreased the negative effects of oxidative stress on fatty acids. The results of this study provide supporting evidence for the potential use of sodium tetraborate in drug design to prevent the toxic effects of lead.
- MakaleYalnız künye2026Scopus SJRQ1Feeding problems in Turkish children with down syndrome and parental quality of life: A cross-sectional study
Okyar, Ferit; Kemer, Duygu
Background Children with Down syndrome (DS) often have feeding problems, which may negatively affect the quality of life (QoL) of their parents. This study aimed to identify feeding problems in children with DS and to examine the relationship between these feeding problems and parental QoL. Methods This cross-sectional study included 105 parents of children aged 10–18 years with DS in Turkey. Data were collected through face-to-face interviews using the Screening Tool of Feeding Problems (STEP) and the SF-36 Health Survey (SF-36). Results This study indicated that the mean STEP scale scores were below the average level across all frequency × severity subscales. Parents' mean scores on the SF-36 QoL scale were above the reference mean (x̄ = 50.00) for the physical functioning, vitality, mental health, social functioning, pain, and general health perception subscales, whereas scores for the physical role limitation and emotional role limitation subscales were below the reference mean. In this study, a moderate negative correlation was found between STEP subscale scores and parents' mean SF-36 subscale scores ( p ≤ 0.05). Conclusions In this study, a significant negative correlation was found between the STEP subscale scores and the parents' mean SF-36 subscale scores. Implications to practice: Routine feeding assessments using the STEP scale should be conducted for children with DS, and nurse-led parent education programs addressing feeding problems should be implemented.
- MakaleAçık Erişim2026Scopus SJRQ1Ajuga vestita Boiss: a “natural gold mine” for the design of novel nutraceuticals and phytopharmaceuticals
Cetiz, Mehmet Veysi; Zengin, Gokhan; Leyva-Jiménez, Francisco Javier; Fernández-Ochoa, Álvaro; de la Luz Cádiz-Gurrea, Maria; Custódio, Luísa; Rodrigues, Maria João; Pereira, Catarina G.; Lazarova, Irina; Balos, Mehmet Maruf
Members of the Ajuga genus are of significant interest due to their traditional applications in various countries, and have therefore been the subject of phytochemical research investigating their natural bioactive compounds. The aim of this study was to determine the chemical composition and biological activities of various Ajuga vestita extracts (ethyl acetate, ethanol, ethanol/water and water). The biological effects assessed included antioxidant, enzyme inhibition and cytotoxic activities. The extracts were chemically profiled using ultra-high-performance liquid chromatography – electrospray ionization – quadrupole time-of-flight mass spectrometry (UHPLC-ESI-QTOF-MS), which identified 121 compounds, including iridoids, flavonoids, and phenolic acids. The ethanol/water extract exhibited superior radical scavenging activity (2,2-Diphenyl-1-picrylhydrazyl (DPPH): 43.13 mg Trolox equivalent (TE)/g; 2,2-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS): 45.37 mg TE/g) and reducing power (cupric reducing antioxidant capacity (CUPRAC): 103.43 mg TE/g; ferric reducing antioxidant power (FRAP): 45.29 mg TE/g). Regarding enzyme inhibition, the ethanol extract exhibited the greatest inhibition of acetylcholinesterase (AChE), butyrylcholinesterase (BChE), glucosidase, and tyrosinase, whereas the ethyl acetate extract was most effective against amylase. Regarding cytotoxicity, the ethyl acetate extract exhibited the strongest effect, significantly reducing cell viability in all cell lines and having a particularly strong impact on murine bone marrow stromal (S17) cells, with viability at 30.8 ± 2.7% at a concentration of 100 µg/mL. By contrast, the aqueous extract exhibited low cytotoxicity, maintaining high cell viability (over 94% at 50 µg/mL and over 74% at 100 µg/mL). Additionally, network pharmacology, molecular docking and molecular dynamics simulations were employed to investigate the multi-target mechanisms and binding stability of A. vestita phytochemicals. These findings provide new, detailed insights into A. vestita and suggest its potential as a raw material for developing health-promoting nutraceutical and pharmaceutical products.
- MakaleYalnız künye2026Scopus SJRQ2Postural control impairment in chronic obstructive pulmonary disease (COPD): The role of respiratory muscle weakness and spinal curvature
Topcuoğlu, Ceyhun; Ozel, Alp; Tutun Yumin, Eylem; Sertel, Meral; Tug, Tuncer
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with respiratory muscle dysfunction, postural alterations and balance impairment. However, the impact of respiratory muscle weakness on postural control and its relationship with spinal curvature and mobility remain insufficiently clarified. OBJECTIVES: The objectives of this study were to compare postural control in individuals with COPD with and without respiratory muscle weakness; to examine the relationship among spinal curvature, spinal mobility, postural control and respiratory muscle strength; and to determine the effect of respiratory muscle strength on postural control. METHODS: This cross-sectional study included 41 clinically stable individuals with COPD aged 40–75 years. Respiratory muscle strength was assessed using a mouth pressure measurement device. Postural control and balance were evaluated with the Biodex Balance System and functional tests. Higher stability index values indicate greater postural sway and poorer balance performance, whereas lower values reflect better postural stability. Spinal curvature and mobility were assessed using the Spinal Mouse®. RESULTS: Individuals with respiratory muscle weakness showed significantly higher overall, anterior–posterior and medial–lateral stability indices, as well as worse eyes-open and eyes-closed firm-surface indices compared to those without weakness (p < 0.05). In participants with severe and very severe COPD, thoracic kyphosis angle was significantly associated with MIP, MIP% and multiple balance indices under different surface and visual conditions (p < 0.05). CONCLUSIONS: Respiratory muscle weakness is associated with impaired postural control and balance performance in individuals with COPD, and thoracic spinal curvature appears to be linked to both respiratory muscle strength and balance outcomes.
- MakaleAçık Erişim2026Scopus SJRQ1The Efficacy of Structured Exercise Program Versus Aerobic Exercise in Tension-Type Headache: A Randomised Clinical Trial
Ataş, Kübra; Mutlu, Ebru Kaya
Background: Despite the widespread use of exercise in managing tension-type headache, there remains a lack of research on the effectiveness of combined structured exercise programs. The aim of this study was to investigate the effects of a structured exercise program versus aerobic exercise of equal duration on tension-type headache (TTH). Methods: Fifty-four female participants aged between 18 and 55 years were randomised to receive a 12-week exercise program, conducted twice a week for 45 min per session. The Structured Exercise Group (SEG) participated in a combination of aerobic, strengthening, and stretching exercises, whereas the Aerobic Exercise Group (AEG) performed only aerobic exercises. The primary outcome measure was the Headache Impact Test (HIT-6), a quality-of-life questionnaire. Secondary outcome measures included headache intensity, disability level, pressure pain threshold, proprioception, muscle strength, cervical posture, exercise capacity, anxiety, and depression. Results: Both groups showed statistically significant improvements in quality of life, pain intensity, disability, anxiety, depression, exercise capacity, pressure pain threshold, and proprioception (p < 0.05). Between-group comparisons revealed that the SEG demonstrated significantly greater improvements in quality of life, pressure pain threshold, proprioception, muscle strength, and posture (p < 0.05), whereas the AEG showed superior gains in exercise capacity (p < 0.05). Conclusion: Both exercise programs appear similarly effective for self-reported outcomes. Based on clinical measurement results, we recommend incorporating strengthening and stretching exercises into the aerobic exercise program and extending the duration to 12 weeks for additional benefits. Significance Statement: This study highlights the clinical value of supervised, physiotherapist-led exercise and the integration of personalised, multi-component strategies in managing tension-type headache. While both structured and aerobic programs improved pain, activity, and participation, the structured approach provided additional benefits in pressure pain threshold, proprioception, muscle strength, and posture. Tailoring interventions to individual clinical needs and extending the duration beyond 8 weeks may further enhance outcomes.
- MakaleAçık Erişim2025Çocuk Görüşme Merkezleri: “Yararlanıcıların Perspektifinden Bir İnceleme”
Akgül, Ceylan Sülü; Berk, Cansu
Sosyal hizmet uygulamaları açısından çocuğun üstün yararını gözeten, ebeveynlerin ve çocukların iyilik halini ve refah düzeyini arttıran, çocuğun temel haklarını koruma altına alan Çocuk Görüşme Merkezleri (ÇGM) sosyal hizmet alanında 2022 yılı Nisan ayından beri uygulanmaktadır. Bu çalışma kapsamında Çocuk Görüşme Merkezlerinden hizmet alan 10 ebeveyn ve 1 birinci derece yakın (anneanne) ile derinlemesine görüşmeler yapılarak elde edilen bulgular MAXQDA programı ile analiz edilmiştir. Elde edilen bulgular hizmetten yararlanan bireylerin; Hizmet Hakkındaki Düşünceleri-Eski Eşle Karşılaşmamak, İcra Yoluyla Çocuğun Alınmaması, Kurum Adı ve Kurum Tarafından Aranmak, Hizmeti Nasıl Öğrendikleri, Hizmete Başvurma Nedenleri, ÇGM’ ye İlişkin Değerlendirmeleri- Olumlu Yanlar, Görev Yapan Personel, Fiziki Yapı, ÇGM’nin Çocuk ve Ebeveyn Üzerindeki Etkisi- Ebeveynler/Çocuklar Üzerindeki Etkisi ve Öneriler ana tema ve alt temalarına ayrılarak tematik analiz yöntemiyle deşifre edilmiştir. Elde edilen bulgularda hizmetin olumlu yanları bilhassa eski eş ile karşılaşmama, mahkeme tarafından belirlenen gün ve saatlerde çocuğu düzenli olarak görebilme, çocuğu diğer ebeveynden görevli uzman aracılığıyla güvenli bir ortamda alma ve çocuğun üstün yararını göz ardı eden icra uygulamasının son bulması yönündeki anlatılar öne çıkmıştır. Gerek hizmetin Türkiye için yeni olması gerekse de hizmetten yararlanan ebeveynler perspektifinden kaleme alınan ilk eser olması nedeniyle bu çalışmanın alana önemli bir katkı sağlayacağı ve büyük bir boşluğu dolduracağı düşünülmektedir.
AtıfTR Dizin1
İncele - MakaleAçık Erişim2025Pandemi Döneminde Hemşire Ebeveynin Çocuğu Olmak: Nitel Bir Çalışma
Durmaz, Yadigar Çevik; Kuzu, Ayşe; Öztürk, Pınar Çiçekoğlu
Amaç: Bu çalışma hemşire ebeveynlerin çocuklarının COVID-19 pandemi algısı ve pandemi dönemindeki deneyimlerinin incelenmesi amacıyla yapılmıştır. Yöntem: Nitel araştırma yöntemlerinden fenomenoloji deseni kullanılarak yapılan bu çalışma, 1 Ocak–1 Mart 2021 tarihleri arasında pandemi sürecinde çalışan, 3-7 yaş grubunda çocuğu olan hemşireler ve onların çocukları ile gerçekleştirilmiştir. Ebeveynlere kartopu örnekleme yöntemi ile ulaşılmış 23 ebeveyn-çocuk çifti (23 ebeveyn ve 23 çocuk) ile çalışma tamamlanmıştır. Çalışmanın verileri ebeveynler ve çocuklar için geliştirilmiş yarı yapılandırılmış formlar aracılığı ile toplanmıştır. Verilerin analizinde MAXQDA 2022 bilgisayar programı kullanılmıştır. Bulgular: Ebeveynler ve çocuklarla yapılan görüşmeler sonunda iki ana tema belirlenmiştir. Birinci tema olan değişen ebeveyn çocuk ilişkisi, pandemiden önce ebeveyn çocuk ilişkisi ve pandemiden sonra ebeveyn çocuk ilişkisi olmak üzere iki alt temadan oluşmaktadır. İkinci tema olan pandeminin çocuklar üzerindeki etkileri ise çocuklar için koronavirüsün anlamı, ebeveynin gözünden çocukların yaşamında korona virüs, çocukların yetkililerden isteği ve ebeveynlerin gözünden çocukların duygu ve davranışları olmak üzere dört alt temadan oluşmaktadır. Sonuç: Bu çalışmanın sonucunda, pandemi döneminde çocukların hemşire ebeveynleri ile geçirdiği zamanın azaldığı, ilişkinin şeklinin değiştiği ve çocukların duygu ve davranışlarında olumsuz değişimler meydana geldiği belirlenmiştir.
- MakaleAçık Erişim2025The Relationship between Copper Tolerance and Antibiotic Susceptibility of Vagococcus salmoninarum Isolated from Kılavuzlu Dam Lake
Gokhan, Haci Bayram; Ispır, Ünal; Özcan, Mikail; Şeker, Engin
The contamination of aquatic ecosystems by heavy metals has been identified as a significant environmental hazard for aquatic animal species, including fish. The objective of this study was to investigate the tolerance of Vagococcus salmoninarum bacteria to copper and the impact of copper exposure on antibiotic susceptibility. The bacterial isolates, comprising six strains, were obtained from rainbow trout reared in cage culture at Kılavuzlu Dam Lake. The initial assessment of antibiotic susceptibility was conducted using the Kirby-Bauer disc diffusion method, which was subsequently validated through the determination of minimum inhibitory concentration (MIC). The broth microdilution method was employed, with the bacterial isolates exposed to concentrations of copper sulphate ranging from 0.1 to 1 mM. The resistance to multiple antibiotics was altered to be significantly altered following exposure to copper sulphate. The minimum inhibitory concentration (MIC) value of copper was observed to be 0.4 mM against V. salmoninarum. It was noted that V. salmoninarum, which has been exposed to copper in its natural environment, has developed the capacity to withstand stress and has undergone a change in its physiological status.
- MakaleAçık Erişim2025The effect of peer bullying on the academic achievement of university students
Korkmaz, Mehmet; Yildirim, Hasan Şahin
The aim of the research is to reveal the relationship between peer bullying experienced by university students and their academic achievements according to the views of the university students. The study group determined by criterion sampling method consists of 372 university students studying at Munzur University in the 2023-2024 academic year in Tunceli province. "Peer Bullying Identification Scale-Adolescent Form" and "Personal Information Form" were used in the research. SPSS 27 and Lisrel 8.8 software packages were used for the scale's validity and reliability analyses. According to the findings of the research, it was concluded that the average scores of university students for experiencing bullying and bullying others were low. As a result of the Spearman’ Rho test, which was conducted to determine the relationship between peer bullying experienced by students and their academic achievement, a negative, significant and low level relationship was revealed between peer bullying and academic achievement.
AtıfOpenAlex2TR Dizin1İncele - MakaleAçık Erişim2025The Relationship between COVID-19 Phobia and Fear of Death among Women: A Web-Based Correlational Descriptive Study from Türkiye
Taşçı Beydağ, Kerime Derya; Dal, Nursel Alp; Gumussoy, Sureyya
Objective: This study was conducted to determine the COVID-19 phobia and fear of death levels in women during the COVID-19 pandemic period. Methods: This descriptive-correlational study was carried out using the snowball sampling method by sharing questionnaires through social media sites and social networks, with 2040 women in Türkiye who agreed to participate in the study. Results: The data were obtained with the COVID-19 Phobia Scale (C19P-S) and the "one's own death" subscale of the Collett-Lester Fear of Death Scale (CL-FODS). A moderate, positive, significant linear relationship was observed between the participants’ fear of death and COVID-19 phobia scores. Conclusions: As a result of this study, it was determined that fear of death increased as COVID-19 phobia increased, and the participants who knew individuals in their immediate environment who had experienced the disease or died of it were affected more negatively by the pandemic period.
- Derleme MakaleAçık Erişim2025Covid-19 Pandemisinde Neoliberal Politikalar: Sosyal Devletin Sağlıkta Eşitlik ve Hakkaniyeti Sağlamadaki Rolü
Baş, Kazım
Sağlık hizmetlerinde eşitsizliklerin azaltılması ve hakkaniyetin sağlanması, devletler için her zaman zorlu bir mücadele süreci olmuştur. Neoliberal ekonomik politikaların etkisiyle bu durum daha da karmaşık hale gelmiştir. Bu çalışmada, Covid-19 pandemi sürecinde, dünya genelinde etkili olan neoliberal politikaların etkisinde sosyal devletin sağlıkta eşitlik ve hakkaniyeti sağlamadaki rolü literatür kapsamında değerlendirilmiştir. Ülkeler arası ve ülkeler içinde sağlıkta eşitsizliklerin oluşumunda; sağlığın sosyal belirleyicileri olarak bilinen bireysel, sosyal, ekonomik ve çevresel faktörlerin yer aldığı bildirilmiştir. Sağlıklı bir topluma ulaşmada eşitlik ve hakkaniyet, temel unsurlar arasında yer almakta olup, devletin, sağlık hizmetlerinde, sosyal politikalar aracılığıyla hakkaniyeti sağlama ve sağlık eşitsizliklerini azaltmada rolü önemlidir. Ancak neoliberal politikalar sosyal devletin sağlık hizmetlerindeki rolünü olumsuz etkileyerek sınırlandırdığından, sağlık hizmetlerindeki eşitsizliklerin daha da arttığı görülmektedir. Neoliberal politikaların devletin sağlık alanındaki düzenleyici ve sosyal refahı gözeten rolünü zayıflatması, çoğu ülkede, Covid-19 salgın yönetiminde ciddi yetersizliklere yol açmıştır. Covid-19 sağlık krizinin aşılmasında, devletin yeniden sosyal rolü üstlenerek salgın yönetimi ve kontrolünde etkin baş aktör olduğu görülmüştür.
AtıfOpenAlex1İncele - MakaleAçık Erişim2025Covid-19 Salgının Türkiye’de Uzun Dönemli İşsizliğe Etkileri
Acun, Serdar
COVID-19 salgını, küresel iş gücü piyasasında büyük değişimlere neden olmuştur. Salgın döneminde işsizlik artarken istihdam azalmış, 2020 yılında çalışma süreleri 2019’un son çeyreğine kıyasla 255 milyon tam zamanlı işe eşdeğer bir kayıp yaşamıştır. Bu kayıp, 2008 küresel finansal krizindekinin dört katı büyüklüğündedir. İş arama süreleri uzamış ve uzun dönemli işsizlik oranları ciddi oranda yükselmiştir. Türkiye’de 2019 yılında uzun dönemli işsizler toplam işsizlerin %23’ünü oluştururken, bu oran 2022 sonunda %31’e ulaşmıştır. Bu çalışmada, salgın öncesi ve sonrası uzun dönemli işsizliğin belirleyicileri incelenmiştir. 2019-2023 verilerine dayalı lojistik regresyon analizinde bağımlı değişken olarak uzun dönemli işsizlik; bağımsız değişkenler olarak cinsiyet, yaş, eğitim, iş deneyimi gibi faktörler kullanılmıştır. Türkiye emek piyasasının en önemli sorunlarından biri olan emek arzının niteliğiyle emek talebinin niteliği arasındaki uyuşmazlık bu çalışmada da görülmüştür. Eğitimli nüfusun uzun dönemli işsizlikte olma olasılığı daha fazladır. Türkiye emek piyasasının kadına iş yaratmadaki sıkıntısı bu çalışmada da ortaya çıkmış ve kadınların uzun dönemli işsizlikte olma olasılığı erkeklere göre daha fazla olduğu bulunmuştur.
- MakaleAçık Erişim2025Türkiye in the Framework of the Preston Curve and Wilkinson Hypothesis: The Transformation of Income Growth, Income Distribution, and Life Expectancy
Sarı, Sacit
This study examines the validity of the Preston Curve and Wilkinson Hypothesis in the context of the Turkish economy, analyzing the impact of per capita income, income inequality, and public health expenditures on life expectancy. Using data from 1960 to 2022, graphical analysis and time series methods were employed to investigate the relationships between these variables. The key findings indicate that the Preston Curve is valid for Türkiye, as higher per capita income increases life expectancy, but the effect diminishes beyond a certain income level. A negative and statistically significant relationship was found between income inequality and life expectancy, supporting the Wilkinson Hypothesis. Additionally, public health expenditures positively and significantly influence life expectancy, highlighting the importance of government investments in healthcare. The findings suggest that the impact of economic growth on health indicators is not solely determined by rising income levels but also by the reduction of income inequality and increased public health expenditures. Policy recommendations include expanding healthcare spending, implementing social policies to mitigate income inequality, and addressing regional disparities in healthcare access.
