Yazarlar
- Gul, Muhammet(35)
- Erten, Fusun(23)
- Zengin, Gokhan(23)
- Benzer, Fulya(22)
- Dal, Nursel Alp(20)
- Sahin, Kazim(20)
- Orhan, Cemal(19)
- Yeşiltepe, Akgün(17)
- Topal, Murat(15)
- Yucesan, Melih(15)
- Yildirim, Ozal(13)
- Öbek, Erdal(13)
- Aksakal, B.(12)
- Gürarslan Baş, Nazan(12)
- Alp Dal, Nursel(11)
- Baloglu, Ulas Baran(11)
- Cakilcioglu, Ugur(11)
- Kandemir, Fatih Mehmet(11)
- Paksoy, Mehmet Yavuz(11)
- Talo, Muhammed(11)
- Celik, Erkan(10)
- Er, Besir(10)
- Say, Yakup(10)
- Yaman, Mine(10)
- Yüksekol, Özlem Doğan(10)
- Aksu, Önder(9)
- Aslan, N.(9)
- Aslan, Naim(9)
- Baş, Kazım(9)
- Erişir, Mine(9)
- Mahomoodally, Mohamad Fawzi(9)
- Acharya, U. Rajendra(8)
- Caprioli, Giovanni(8)
- Karatay, Gülnaz(8)
- Kocabaş, Mehmet(8)
- Macit, Arife(8)
- Parlak Ak, Tuba(8)
- İpek, Yeliz(8)
- Beydağ, Kerime Derya(7)
- Camas, Mustafa(7)
Yayınlar
- MakaleAçık Erişim2018Scopus SJRQ4Effects of Different Plant Oils Having Different Oxygen Radical Absorbance Capacity (ORAC) on Hematological Parameters of Rainbow Trout (Oncorhynchus mykiss) at High Stocking Density
Aksu, Önder; Altınterim, Başar; Kutluyer Kocabaş, Filiz
In this study, macerated oils of different plant [sunflower (Helianthus annuus), onion (Allium cepa), garlic (Allium sativum), basil (Ocimum basilicum), opium poppy (Papaver somniferum), ginger (Zingiber officinale), turmeric (Curcuma longa)] were obtained. The study was conducted at a total of 7 groups, including the control group (sunflower oil), in 30 liter aerated tanks without water circulation during a week. Twenty rainbow trout per tank (14.6±1.0 g) were stocked at high density. Macerated oils were applied to the skin of the fish along the lateral line on the first day. For determination of effects of macerated oils on water and fish, oxidationreduction potential (ORP) of water and hematological parameters [granulocyte (GRAN), white blood cell (WBC), red blood cell (RBC), hemoglobin (HGB), mean corpuscular hemoglobin (MCH), red cell distribution width (RDW-SD), mean platelet volume (MPV), platelet distribution width (PDW), platelet large cell ratio (P-LCR)] were examined in fish. The results indicated that decreases were determined in ORP level of water. It was determined that the highest survival rate was in the application of basil oil. At the end of 7 days, the highest WBC, LYM, HGB, MCV, MCH, MPV values were determined in the application of ginger oil (ORAC: 28.811). It was determined that the highest RBC value was in the application of turmeric oil (ORAC: 159.277), the highest GRAN value was in the application of poppy oil (ORAK: 481), the highest HCT, PLT values was in the application of basil oil (ORAC: 67.553). At the end of the study, it was determined that the macerated oil application to lateral line induced blood parameters.
AtıfOpenAlex3TR Dizin7
İncele - MakaleYalnız künye2018Lifelong learning tendencies of classroom teachers
Karakaya Cirit, Didem; Gökyer, Necmi
The aim of this research is to determine the lifelong learning tendencies of classroom teachers and to compare them with various variables. In the research, the following questions have been answered.1. What is the level of life-long learning tendencies of classroom teachers? 2. Do the lifelong learning attitudes of the teachers differ significantly according to their gender, seniority, level of education, age, and place of work? 3. Is there a meaningful relationship between subscales of the scale? This research is in the instant scanning model. The universe of the research constitutes a total of 1116 classroom teachers who are in primary schools in the centre of Elazığ and its districts in the academic year of 2017-2018. The sample is composed of 291 teachers determined by simple random sampling. In the research, the scale of "Lifelong Learning Trends" (YBÖEÖ) developed by Diker Coşkun and Demirel (2009) is used as data collection tool. In this study, the internal consistency coefficient of the scale was found as .87. The internal consistency coefficient of the motivation sub-dimension of the scale was .92, the internal consistency coefficient of the persistence sub-dimension was .93, the internal consistency coefficient of the deprivation sub- dimension was .83 and the internal consistency coefficient of the curiosity deprivation sub-dimension was .94. According to findings of this study; the life-long learning tendencies of the class teachers are at the level of “partially fits” in the sub-dimensions of motivation, persistence, lack of curiosity and in the whole scale; but in the sub-dimension of lack of regulation of learning at the level of “little fits”. According to the gender variable, in all sub-dimensions, the lifelong learning tendencies of women class teachers are higher than that of men.
AtıfOpenAlex4TR Dizin2İncele - MakaleAçık Erişim2018Bir Kamu Üniversitesi Çalışanlarında Aktif ve Pasif Sigara İçicilik Durumu, Bağımlılık Düzeyi ve Değişimin Aşamaları
Karatay, Gülnaz; Gürarslan Baş, Nazan
Amaç: Bu çalışmanın amacı bir kamu üniversitesinde çalışanların aktif ve pasif sigara içicilik durumunu,bağımlılık düzeyini ve içinde bulunduğu değişimin aşamasını değerlendirmektir. Yöntem: Tanımlayıcı türdenyapılan bu çalışmanın evrenini 2015-2016 öğretim yılında Türkiye’nin doğusunda bir üniversitede görev yapanakademik, idari ve diğer personeller oluşturdu. Evrenin tamamı örneklem kapsamına alınmış olup, 230 (evrenin%57.5’i) çalışandan elde edilen veriler değerlendirmeye alındı. Araştırmanın verileri “Üniversite ÇalışanlarındaSigara Bağımlılığı Soru Formu”, “Fagerström Nikotin Bağımlılık Testi” ve sigara için uyarlanmış “DeğişimAşamaları Testi ” kullanılarak toplandı. Elde edilen veriler, bilgisayar destekli SPSS 18.0 programında sayı,yüzdelikler ve önemlilik testi olarak da ki-kare kullanılarak analiz edildi. Bulgular: Çalışmaya katılan bireylerin%16.5’i ara sıra, %30.4 ünün düzenli olarak sigara içtiğini, %10.4’ü ev ortamında, %23.9’u ise iş yerinde pasifsigara dumanına maruz kaldığını ifade etti. Kadınlarda ve akademisyenlerde sigara içme oranları daha fazla iken,diğer çalışanların pasif sigara dumanına daha fazla maruz kaldığı görüldü (p<.05). Katılımcıların %37.6’sındaorta düzeyde, %16.8’inde ise ileri düzeyde nikotin bağımlılığı olduğu ve %42.4’ünün sigara bırakma ile ilgili niyetöncesi aşamada ve %32.7’sinin niyet aşamasında olduğu saptandı. Sonuç: Bu çalışmada elde edilen bulgulara göreüniversite çalışanlarının yarıya yakını aktif sigara içicisi olup, yaklaşık her beş çalışandan birinin pasif sigaradumanına maruz kaldığı, kadınlarda ve akademisyenlerde sigara bağımlılığının daha fazla olduğu görüldü.
AtıfOpenAlex1TR Dizin1İncele - MakaleYalnız künye2018Scopus SJRQ1In vitro biological properties and predicted DNA-BSA interaction of three new dicyanidoargentate(I)-based complexes: synthesis and characterization
Karadag, Ahmet; Korkmaz, Nesrin; Aydin, Ali; Tekin, Saban; Yanar, Yusuf; Yerlif, Yusuf; Korkmaz, Sengul Aslan
AtıfOpenAlex13
İncele - MakaleYayıncıda açık erişim2018Scopus SJRQ2Cancer treatment model with the Caputo-Fabrizio fractional derivative
Ali Dokuyucu, Mustafa; Celik, Ercan; Bulut, Hasan; Mehmet Baskonus, Haci
In this article, a model for cancer treatment is examined. The model is integrated into the Caputo-Fabrizio fractional derivative first, to examine the existence of the solution. Then, the uniqueness of the solution is investigated and we identified under which conditions the model provides a unique solution.
AtıfScopus241OpenAlex244
İncele - MakaleYalnız künye2018Scopus SJRQ1The Effect of Therapeutic Clowning on Handwashing Technique and Microbial Colonization in Preschool Children
Arıkan, Duygu; Gürarslan Baş, Nazan; Kurudirek, Fatma; Baştopcu, Ayşe; Uslu, Hakan
Purpose: This study aimed to determine the effect of therapeutic clowning on handwashing technique and microbial colonization in preschool children. Design: This randomized controlled trial was conducted using pre-test and post-test experimental and control groups. Methods: The study was conducted between March and June 2016 in two kindergartens in eastern Turkey. The study was completed with a total of 195 students, including 90 students in the experimental group and 105 students in the control group. A questionnaire was used for data collection. This questionnaire included sections about the subjects’ descriptive characteristics and the results of the bacterial cultures of their hand swabs. For the collection of these swabs, the subjects were informed in advance, and samples were collected at predetermined times. The swabs were analyzed to determine the bacterial colonization of the subjects’ hands. Clowns and video activities were used as intervention tools in the study. Findings: In the post-test, the microbial growth was ≤103 in 68.9% and >103 in 31.1% of the subjects in the experimental group. In contrast, the growth was ≤103 in 34.3% and >103 in 65.7% of the control group subjects. The difference in the post-test microbial growths of the two groups was statistically significant (p <.000). Conclusions: The hygienic handwashing technique taught in the therapeutic clowning and videos reduced the bacterial colonization on the preschool children's hands by 50%. Moreover, this method was effective in reducing the growth rate of coliform bacteria that indicate undesirable, poor hygiene of the hands. Clinical Relevance: Considering these results, we recommend that pediatric healthcare professionals use entertaining methods such as those involving clowns to teach and guide children regarding hygienic handwashing techniques.
AtıfScopus11WoS10OpenAlex12
İncele - MakaleYalnız künye2018Scopus SJRQ2Fuzzy rule-based Fine–Kinney risk assessment approach for rail transportation systems
Gul, Muhammet; Celik, Erkan
Rail transportation is one of the most crucial public transportation types for big and crowded cities. In rail transportation systems, stakeholders face serious issues involved in workshops, stations, lines and their environments, and general office buildings. In order to reach an increased awareness and better occupational health and safety (OHS) management, a new risk assessment approach is proposed in this study. This approach includes a combination of Fine–Kinney method and a fuzzy rule-based expert system. It captures nonlinear causal relationships between Fine–Kinney parameters. Since there is a high level of vagueness involved in the OHS risk assessment data, the rule-based expert system is developed for probability (P), exposure (E), and consequence (C) for evaluating risk score. A case study is carried out in a rail transportation system in Istanbul/Turkey, and a comparison with the classical Fine–Kinney method is discussed. Results of the case study reveal risk clusters and corresponding control measures that should be taken into consideration. The study methodologically contributes to risk assessment in the knowledge, while case study in a real rail transportation system offers an insight into public transport industry in safety improvement.
AtıfScopus81WoS71OpenAlex86İncele - MakaleYayıncıda açık erişim2018Scopus SJRQ3Spectral, thermal and antimicrobial properties of novel mixed ligand-metal complexes derived from saccharinate complexes and azo dye ligand
Adiguzel, Ragip; Turan, Nevin; Buldurun, Kenan; Korkoca, Hanifi
Background and Objective: Saccharin and saccharinate (sac) complexes and its anion have critical importance with biological, biochemical and pharmacological properties. The main objective of this study was to synthesize the novel mixed ligand complexes from the complexes [M(Sac)2(H2O)4]·2H2O [M: Mn(II), Co(II), Ni(II), Cu(II) and Cd(II)] with a second neutral ligand [L:(mmppa): 5-Methyl-4-(4-methylphenylazo)-2H-pyrazole-3-ylamine]. Methodology: The structures of the complexes were characterized by elemental analysis, magnetic susceptibility, FT-IR, mass and electronic spectral studies and thermal analysis. Antimicrobial (antibacterial and anticandidal) activities of the complexes were tested against Enterococcus faecalis ATCC 51299, Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 35218, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 700603 and Candida albicans ATCC 64548. Results: According to the experimental results, it was determined that in Mn(II), Co(II) and Cd(II) complexes, two coordinated H2O molecules are replaced with two neutral ligands, on the other hand, in Ni(II) and Cu(II) complexes, all coordinated H2O molecules are replaced with four neutral ligands. It was established that the second neutral ligand was coordinated to the metal ions via nitrogen atom of-NH2 group in pyrazole ring. In antimicrobial activity, study was determined to occur significant inhibition zones (20-24 mm) against Candida albicans ATCC 64548 strain. Conclusion: As a result, mononuclear and monomeric structure in octahedral geometry including both saccharin and azo dye ligands were synthesized and their characterizations were accomplished. The result of this study shows that novel mixed ligand-saccharinate complexes can be utilized for the development of anticandidal agents.
AtıfScopus11WoS10OpenAlex11İncele - MakaleYalnız künye2018Scopus SJRQ2Arrhythmia detection using deep convolutional neural network with long duration ECG signals
Yıldırım, Özal; Pławiak, Paweł; Tan, Ru-San; Acharya, U. Rajendra
This article presents a new deep learning approach for cardiac arrhythmia (17 classes) detection based on long-duration electrocardiography (ECG) signal analysis. Cardiovascular disease prevention is one of the most important tasks of any health care system as about 50 million people are at risk of heart disease in the world. Although automatic analysis of ECG signal is very popular, current methods are not satisfactory. The goal of our research was to design a new method based on deep learning to efficiently and quickly classify cardiac arrhythmias. Described research are based on 1000 ECG signal fragments from the MIT - BIH Arrhythmia database for one lead (MLII) from 45 persons. Approach based on the analysis of 10-s ECG signal fragments (not a single QRS complex) is applied (on average, 13 times less classifications/analysis). A complete end-to-end structure was designed instead of the hand-crafted feature extraction and selection used in traditional methods. Our main contribution is to design a new 1D-Convolutional Neural Network model (1D-CNN). The proposed method is 1) efficient, 2) fast (real-time classification) 3) non-complex and 4) simple to use (combined feature extraction and selection, and classification in one stage). Deep 1D-CNN achieved a recognition overall accuracy of 17 cardiac arrhythmia disorders (classes) at a level of 91.33% and classification time per single sample of 0.015 s. Compared to the current research, our results are one of the best results to date, and our solution can be implemented in mobile devices and cloud computing.
AtıfScopus801OpenAlex854İncele - MakaleYalnız künye2018Scopus SJRQ2Trace Metal Levels in Rainbow Trout (Oncorhynchus mykiss) Cultured in Net Cages in a Reservoir and Evaluation of Human Health Risks from Consumption
Varol, Memet; Kaya, Gülderen Kurt; Alp, Sumru Anık; Sünbül, Muhammet Raşit
Although fish consumption has positive health effects, metals accumulated in fish can cause human health risks. In this study, the levels of ten metals in rainbow trout (Oncorhynchus mykiss) farmed in the Keban Dam Reservoir, which has the biggest rainbow trout production capacity in Turkey, were determined and compared with the maximum permissible levels (MPLs). Also, human health risks associated with rainbow trout consumption were assessed. The metal concentrations in rainbow trout were found below the MPLs. The estimated daily intake of each metal was much lower than the respective tolerable daily intake. The target hazard quotient (THQ) for individual metal and total THQ for combined metals did not exceed 1, indicating no health risk for consumers. The cancer risk (CR) value for inorganic arsenic was within the acceptable lifetime risk range of 10−6 and 10−4. For carcinogenic and non-carcinogenic effects, the maximum allowable fish consumption rates were high enough to ensure the human health. According to these results, the consumption of rainbow trout farmed in the Keban Dam Reservoir does not pose a risk on human health.
AtıfScopus33WoS32OpenAlex33İncele - MakaleAçık Erişim2018Scopus SJRQ3Cypermethrin-induced in vitro alterations on oxidative stress and quality of salmo coruhensis spermatozoa
Kutluyer, Filiz; Kocabaş, Mehmet; Erişir, Mine; Benzer, Fulya
The use of insecticides has been increasing along with increasing agriculture activities and has caused deleterious environmental impacts. Non-target organisms in particular, including fish, are affected by pesticides. In this work, the impacts of cypermethrin (CYP) on sperm oxidative stress markers and sperm motility were investigated in vitro. The CYP concentrations were 0 μg L-1 control, ethanol), 1.025 μg L-1, 2.05 μg L-1 and 4.1 μg L-1. Lipid peroxidation [Malondialdehyde (MDA)], non-enzymatic antioxidants [glutathione (GSH)] and enzymatic [superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT)] activities in sperm cells were examined for determination of oxidative stress status. Our findings showed that motility and survival of sperm cells significantly decreased with exposure to CYP. Biochemical assays revealed that CAT activity and levels of MDA and, GSH increased in spermatozoa based on CYP concentration while activity of GSH-Px and SOD decreased. Consequently, spermatozoa were highly sensitive to CYP exposure. It can be deduced that CYP has the potential to disrupt sperm quality and to cause to oxidative stress in sperm cells of S. coruhensis.
AtıfScopus3WoS3OpenAlex3İncele - MakaleYalnız künye2018Scopus SJRQ1Evaluation of anesthetic potential of rosewood (Aniba rosaeodora) oil as a new anesthetic agent for goldfish (Carassius auratus)
Kizak, Volkan; Can, Erkan; Danabaş, Durali; Can, Şafak Seyhaneyildiz
The aim of this research was to investigate the efficacy of rosewood (Aniba rosaeodora) essential oil (EO) as a new herbal anesthetic compared with camphor (Cinnamomum camphora) EO and commonly used chemical agent 2-phenoxyethanol (2-PE) on goldfish (Carassius auratus). The anesthetic efficacies of these herbal EOs and 2-PE were evaluated in goldfish with mean body weight of 7.36 ± 0.77 g. Fish were exposed to each anesthetic concentrations and the lowest effective concentrations (LECs) were established according to deep anesthesia (AD < 3 min) and full recovery (RF < 5 min) times. RD and CP showed anesthetic characteristics and induced AD. The LECs for each anesthetic were established at 250 μl L−1 for RD (AD; RF → 171 ± 2.28 s; 297 ± 7.69 s), 250 μl L−1 for CP (AD; RF → 129 ± 4.18 s; 291 ± 2.81 s) and 700 μl L−1 for 2-PE (AD; RF → 177 ± 2.35 s; 214 ± 4.93 s). At concentrations of 50, 100, 150, 200 μl L−1 for RD, 50, 100, 150 μl L−1 for CP and 400, 500 μl L−1 for 2-PE failed to induce AD in goldfish. There were significantly differences found among RD, CP and 2-PE concentrations in terms of induction and recovery times (p < 0.05). The fastest AD and RF were obtained by 300 μl L−1 CP (120 ± 1.94 s) and 600 μl L−1 2-PE (190 ± 4.34 s), respectively. Fish exposed to 300 μl L−1 RD and 800 μl L−1 2-PE took slightly longer to achieve AD than 300 μl L−1 CP. Induction and recovery times for EOs and 2-PE were significantly dependent on concentrations. Negative relationships was recorded between AD and RF for all anesthetics. No mortality or adverse effects occurred and fish stayed calm during trials. Results showed that RD was found to be an effective anesthetic as well as CP for goldfish and can be used at least 3-fold lower concentrations than 2-PE. In conclusion, rosewood (Aniba rosaeodora) EO, as a new potential anesthetic for fish, proved to be an effective natural agent resulting in rapid induction and recovery.
AtıfScopus25WoS20OpenAlex23İncele - MakaleAçık Erişim2018The antiiflammatory effect of Ginkgo biloba in lipopolysaccharide-induced rat sepsis model
Ilhan, Nevin; Susam, Solmaz; Ak, Tuba Parlak; Baykalir, Burcu Gul
Background: Sepsis is characterized dysregulated inflammatory response and is the leading cause of organ failure or injury and death in critical care units. Ginkgo biloba extract 761 (EGb 761) is characterized by antioxidant activity. There is no clear data in the functional role of EGb 761 that inhibiting of proinflammatory cytokines exist in sepsis. The purpose of this study was to investigate the antiinflammatory effect of EGb 761 on the levels of vascular endothelial growth factor (VEGF), matrix metalloproteinase-9 (MMP-9) and inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS) induced rat sepsis model. Methods: The animals were randomly divided into the following six groups: the control, LPS, flunixin meglumine (FM), EGb 761, LPS + FM and LPS + EGb 761 groups. Enzyme-linked immunosorbent assay (ELISA) analysis was applied to measure serum levels of VEGF, MMP-9, and iNOS. Results: Serum iNOs (p < 0.05), VEGF (p < 0.01) and MMP-9 (p < 0.05) levels were significantly higher in the sepsis group. Treatment with EGb 761 decreased serum iNOs levels (p < 0.01), VEGF and MMP-9 levels decreased significantly (p < 0.05). Also, treatment with FM decreased iNOs (p < 0.01), VEGF and MMP-9 levels significantly (p < 0.05). Conclusions: It is suggested that sepsis may lead to increase serum iNOs, MMP-9, and VEGF levels and treatment of EGb 761 may have a potential antiinflammatory effect against LPS-induced sepsis.
AtıfOpenAlex1İncele - MakaleYalnız künye2018Scopus SJRQ1Comparative evaluation of toxicological effects and recovery patterns in zebrafish (Danio rerio) after exposure to phosalone-based and cypermethrin-based pesticides
Korkmaz, Volkan; Güngördü, Abbas; Ozmen, Murat
This study evaluated the toxic effects and recovery patterns in zebrafish (Danio rerio) after exposure to phosalone-based (PBP) and cypermethrin-based (CBP) pesticides. Initially, the 96 h LC50 values of the pesticides were calculated as being 5.35 µg of active ingredient (AI) L−1 for CBP and 217 µg AI L−1 for PBP based on measured concentrations. Accordingly, experimental groups were exposed to three sublethal concentrations of pesticides for 96 h, separately, and then zebrafish were transferred to pesticide-free conditions for 10 and 20 days recovery periods. Biochemical markers were assessed including carboxylesterase (CaE), acetylcholinesterase (AChE), glutathione S-transferase (GST), lactate dehydrogenase, glutathione peroxidase, catalase, alanine and aspartate aminotransferase (ALT, AST) activities after the exposure and recovery periods. Also, the pesticide concentrations in test water were quantified by high-performance liquid chromatography (HPLC) analysis. Our results showed that AChE and CaE activities were significantly inhibited and GST was induced by both pesticides after 96 h exposure. For PBP exposure, the decreases for GST induction and CaE inhibition showed a partial recovery in pesticide-free conditions. However, the decreases in AChE activity for CBP exposure and insufficient increases in same enzyme activity for PBP exposure after 20 days in pesticide-free conditions indicated that the projected recovery period was not enough to the recovery of AChE activities and for the improvement of fish health.
AtıfScopus56WoS50OpenAlex59İncele - MakaleAçık Erişim2018Scopus SJRQ3Maslinic acid as an effective anticancer agent
Lin, Xiukun; Ozbey, Ulku; Uteuliyev, Yerzhan Sabitaliyevich; Attar, Rukset; Ozcelik, Beraat; Zhang, Yuanyan; Guo, Mingyue; Liu, Minghua; Alhewairini, Saleh S.; Farooqi, Ammad Ahmad
Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid) is a naturally occurring pentacyclic triterpenic compound. Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. In this review we will focus on chemopreventive properties of Maslinic acid against different cancers. Seemingly, available data is limited and we have yet to unravel how Maslinic acid therapeutically targeted oncogenic cell signal transduction cascades in different cancers. Moreover, there are visible knowledge gaps about the ability of Maslinic acid to modulate oncogenic and tumor suppressor microRNAs in various cancers.
AtıfScopus20OpenAlex17İncele - MakaleYayıncıda açık erişim2018Scopus SJRQ3The effects of common yarrow (Achillea millefolium Linnaeus), cinnamon (Cinnamomum zeylanicum Blume) and rosemary (Rosemarinus officinalis Linnaeus) hydrosols on the some immunological and hematological parameters of common carp (Cyprinus carpio L., 1758) against to Yersinia ruckeri
Altinterim, Basar; Danabas, Durali; Aksu, Onder
In this study, the effects of some plant hydrosols (distilled plant waters) based upon some hematological parameters and Nitroblue Tetrazolium (NBT) activities in the common carp (Cyprinus carpio Linnaeus, 1758) infected with Yersinia ruckeri were investigated. In the trial, it was utilized totally 200 common carps with 54.3±6.7 g mean live weight and 15.7±1.8 cm mean total lenght. The 10% rate of the common yarrow (Achillea millefolium Linnaeus) hydrosol; 0.5% rate of the cinnamon (Cinnamomum zeylanicum Blume) hydrosol; and 5% rate of the rosemary (Rosemarinus officinalis Linnaeus) hydrosol were applied to fish as a bath treatment. The erythrocyte (RBC), leukocyte count (WBC), hematocrit value (HCT), haemoglobin amount (Hg), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), and activities of NBT in the blood samples taken from the caudal vena of the control and experimental fish groups were analyzed in the 7 th , 14 th , and 21 st days of the exposure treatment. At the end of the research, HCT, Hg, RBC, WBC, MCH and MCV values decreased in the C-2 Group (the control group contain pathogen) compared to the C-1 Group (the control group no contain pathogen), except MCHC value. The NBT activities in the C-1 Groups increased at the 14 th day, but decreased quite a few at the 21 st day. It has been consequently reached the conclusion that the bath treatments of the some plant hydrosols might be beneficial in increasing of antibacterial properties and in strengthening of defense mechanisms of common carp against Y. ruckeri pathogen.
AtıfScopus4WoS4OpenAlex8İncele - MakaleAçık Erişim2018Scopus SJRQ3Effect of Tunceli garlic on some immunological parameters in Cyprinus carpio exposed to chlorpyrifos
Pala, Ayşegül; Şeker, Engin; Yonar, M. Enis
In this study, the effect of Tunceli garlic (Allium tuncelianium) on hemoglobin (Hb) level, oxidative radical production of neutrophils (Nitoblue tetrazolium assay-NBT activity) and total immunoglobulin (TI) content in carp (Cyprinus carpio) exposed to chlorpyrifos (CPF) was investigated. The 96 hour LC50 value of CPF on C. carpio was calculated to as 0.230 mg/L. The fishes were exposed to sublethal concentration of chlorpyrifos (1/8 of LC50 value: 0.029 mg/L), and Tunceli garlic (20 and 40 g/kg diet) was simultaneously administered for 21 days. Blood samples were taken from the fishes at 7, 14 and 21 days and analysed to determine the Hb levels, the NBT activity and the TI content. There was a significant decrease in the Hb level, the NBT activity and the TI content of CPF-treated fish. However, Tunceli garlic reversed the Hb level, the NBT activity and the TI content. In conclusion, this study demonstrated that CPF had a negative effect on the immunological values of the fish. The simultaneous administration of Tunceli garlic was neutralised CPF-induced toxicity.
AtıfScopus5WoS4OpenAlex6İncele - MakaleYalnız künye2018Scopus SJRQ1A comparative outline for quantifying risk ratings in occupational health and safety risk assessment
Gul, Muhammet; Ak, M. Fatih
The concept of risk assessment has been introduced as an examination of safety in the workplace to enable assessments as to whether sufficient precautions have been taken or if more should be done to prevent potential harm. Hazardous industries have faced serious fatalities related to work, workplaces, and workers as a consequence of their high-risk processes. Therefore, in this work, a novel and comparative methodology for quantifying risk ratings in occupational health and safety risk assessment is proposed. A 5 × 5 risk matrix is initially determined, and the fuzzy technique for order preference by similarity to ideal solution (FTOPSIS) method is then applied to rank identified hazards. As a novelty to the knowledge, two parameters of the 5 × 5 matrix method, likelihood and severity, are subjectively assessed by occupational health and safety experts, and then importance levels for these parameters are determined using the Pythagorean fuzzy analytic hierarchy process (PFAHP). In the proposed approach, analysts use linguistic terms and Pythagorean fuzzy sets, which provide greater independence in their evaluations. An outline that enables comparison of the results of this study with the circumcenter of centroids method and the fuzzy AHP-fuzzy VIKOR integrated method in quantifying risk ratings is also provided. In order to present the practicality of this work, a case study in an underground copper and zinc mine is carried out.
AtıfScopus194WoS153OpenAlex211İncele - MakaleAçık Erişim2018Scopus SJRQ2Weaning practices of mothers in eastern Turkey; [Práticas maternas de desmame no leste da Turquia]
Gürarslan Baş, Nazan; Karatay, Gülnaz; Arikan, Duygu
Objective: The study aimed to determine the practices used by breastfeeding mothers to wean their children from the breast. Method: This qualitative–quantitative research was conducted with mothers whose children were registered the pediatric clinics of a state hospital between June and September 2016. In accordance with a purposeful sampling method, 232 mothers of children between the ages of 2 and 5 years were included in the study. Data were collected through face-to-face interviews using a questionnaire with demographic characteristics of mothers as well as their weaning practices. The data obtained were analyzed with a computer-assisted program using number and percentage distributions. Results: The mean breastfeeding duration was 19.00 ± 7.11 months. It was determined that the majority of mothers (56.5%) used traditional methods for weaning their children. These included applying substances with a bad taste (58.1%) to their breasts, covering their breasts with various materials (26.2%) to make the child not want to nurse anymore, and using a pacifier or feeding bottle (9.2%) to substitute for the mother's breast. Conclusions: It was observed that more than half of the mothers were used some traditional practices that could cause trauma in their children, instead of natural weaning.
AtıfScopus18WoS19OpenAlex26İncele - MakaleAçık Erişim2018Investigation of mineral components and antioxidant properties of a healthy red fruit: Cornelian Cherry (Cornus mas L.)
Karaaslan, Merve Goksin; Karaaslan, Nagihan M.; Ates, Burhan
The mineral components of the foodstuff consumed by an individual are important in the growth and development of a human being. In recent years red fruits, because of their potential beneficial health effects, are getting attention of both consumers and manufacturers. One of the red fruits, Cornelian cherry (Cornus mas L.), was investigated in terms of both mineral components and antioxidant properties. The mineral components include calcium (Ca), iron (Fe), potassium (K), magnesium (Mg), and zinc (Zn) in this fruit were determined using flame atomic absorption spectrometry (FAAS). The antioxidant activity tests were applied to the extracts obtained using different solvents to examine the antioxidant properties of this fruit. Statistical analysis indicated that while the best results were obtained from acetone extracts, the lowest results were obtained from water extracts for all antioxidant activity tests (p<0.05). The best average values for DPPH and ABTS radical scavenging capacity, reducing power, total phenolic content and total flavonoid content in acetone extracts were found to be 1053.72±38.12 mg TEAC/100 g FW and 2907.34±152.05 mg TEAC/100 g FW, 5894.99±251.05 mg TEAC/100 g FW, 2979.25±69.40 mg GAE/100 g FW and 255.75±14.92 mg QE/100 g FW, respectively.
AtıfScopus14OpenAlex13TR Dizin3İncele
